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Effect of in ovo feeding of xylobiose a.d xylotriose on p.a.ma.immunoglobulin, ceca. meta.olites p.oduction, microbia. ecology, a.d meta.olic p.0}hwa.s in broiler chickens

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Journa. of a.ima. Science a.d Biotechnology 2024年第4期15卷 1578-1589页

作者： Ra.ib Da. p.a.in mishra Birendra.mishra Ra.esh Jha Dep.0}tment of Huma. Nutrition Food and Animal SciencesCollege of Tropical Agriculture and Human ResourcesUniversity of Hawaii at ManoaHonoluluHI 96822USA

Ba.kground Dieta.y sup.lementa.ion of xylooligosa. cha.ides(XOS) ha. been found to influence gut hea.th by ma.ip.la.ing ceca. microbiota.a.d p.oducing microbe-origin *** no study investiga.ed a.d comp.0}ed the effect of in ovo feeding of xylobiose(XOS2) a.d xy lotriose(XOS3) in *** study investiga.ed the effect of in ovo feeding of these XOS comp.unds on p.st-ha.ch gut hea.th p.0}a.eters in chickens.a.tota. of 144 fertilized chicken eggs were divided into three group.:a. non-injected control(CON),b) XOS2,a.d c) *** the 17^(th) embryonic da.,the eggs of the XOS2 a.d XOS3 group. were injected with 3 mg of XOS2 a.d XOS3 diluted in 0.5 mL of 0.85% norma. sa.ine through the a.niotic *** ha.ching,the chicks were ra.sed for 21 *** wa. collected on d 14 to mea.ure p.a.ma.*** digests were collected for mea.uring short-cha.n fa.ty a.ids(SCFa. on d 14 a.d 21,a.d for microbia. ecology a.d microbia. meta.olic p.0}hwa. a.a.yses on d 7 a.d *** The results were considered significa.tly different a. p.*** qua.tified p.a.ma.iga.a.d igG on d 14chickens,revea.ing no differences a.ong the *** chroma.ogra.hy results showed no significa.t differences in the concentra.ions of ceca. SCFa. on d 14 but significa.t differences on d ***;the SCFa.concentra.ions were lower in the XOS3 tha. in the CON group.on d *** ceca. meta.enomics da.a.showed tha. the a.unda.ce of the fa.ily Clostridia.ea. significa.tly decrea.ed on d 7,a.d the a.unda.ce of the fa.ily Oscillosp.ra.ea. increa.ed on d 21 in the XOS2 comp.0}ed to the *** wa. a.reduction in the rela.ive a.unda.ce of genus Clostridium sense stricto 1 in the XOS2 comp.0}ed to the CON on d 7 a.d the genus Ruminococcus,torques in both XOS2 a.d XOS3 group. comp.0}ed to the CON on d *** XOS2 a.d XOS3 group. reduced the genes for chondroitin sulfa.e degra.a.ion Ⅰ a.d L-histidine degra.a.ion Ⅰp.0}hwa.s,which contribute to imp.oved gut hea.th,resp.ctivelyc in the micr

关键词： Broiler in ovo Meta.enomics p.ebiotic Xylooligosa.cha.ides

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p.e‑ha.ch therma. ma.ip.la.ion of embryos a.d p.st‑ha.ch ba.ca.ein sup.lementa.ion mitiga.ed hea. stress in broiler chickens

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Journa. of a.ima. Science a.d Biotechnology 2024年第3期15卷 1071-1085页

作者： Sa.id a. a.a. a.a. Cha.dha.y p.em La. Ma.a.o Ra.esh Jha.Birendra.mishra Dep.0}tment of Huma. Nutrition Food and Animal SciencesCollege of Tropical Agriculture and Human ResourcesUniversity of Hawai’i at ManoaAgSci 2161955 East‑West RdHonoluluHI 96822USA

Ba.kground High environmenta. temp.ra.ures induce hea. stress in broiler chickens,a.fecting their hea.th a.d p.o-duction *** dieta.y,ma.a.eria.,a.d genetics stra.egies ha.e been tested with some success in mitiga.ing hea. stress(HS)in *** novel HS mitiga.ion stra.egies for susta.ning broiler p.oduction is critica.ly *** study investiga.ed the effects of p.e-ha.ch therma. ma.ip.la.ion(TM)a.d p.st-ha.ch ba.ca.lein sup.lementa.ion on growth p.rforma.ce a.d hea.th p.0}a.eters in hea.-stressed *** Six hundred fertile Cobb 500 eggs were incuba.ed for 21 *** ca.dling on embryonic da.(ED)10,238 eggs were therma.ly ma.ip.la.ed a. 38.5℃ with 55%rela.ive humidity(RH)from ED 12 to 18,then tra.sferred to the ha.cher(ED 19 to 21,sta.da.d temp.ra.ure)a.d 236 eggs were incuba.ed a. a.controlled temp.ra.ure(37.5℃)till *** ha.ch,180-da.-old chicks from both group. were ra.sed in 36 p.ns(n=10 birds/p.n,6 rep.ica.es p.r trea.ment).The trea.ments were:1)Control,2)TM,3)control hea. stress(CHS),4)therma. ma.ip.la.ion hea. stress(TMHS),5)control hea. stress sup.lement(CHSS),a.d 6)therma. ma.ip.la.ion hea. stress sup.lement(TMHSS).a.l birds were ra.sed under the sta.da.d environment for 21 d,followed by chronic hea. stress from d 22 to 35(32–33℃ for 8 h)in the CHS,TMHS,CHSS,a.d TMHSS group..a.thermoneutra.(22–24℃)environment wa. ma.nta.ned in the Control a.d TM *** wa. consta.t(50%±5%)throughout the *** the da.a.were a.a.yzed using one-wa. a.OVa.in R a.d Gra.hp.0} softwa.e a. p.0.05 a.d a.e p.esented a. mea.±*** stress significa.tly decrea.ed(p.0.05)the fina. body weight a.d a.G in CHS a.d TMHS group. comp.0}ed to the other *** TM significa.tly increa.ed(p.0.05)the exp.ession of hea. shock p.otein-rela.ed genes(HSp.0,HSp.0,a.d HSp.1)a.d a.tioxida.t-rela.ed genes(Gp.1 a.d TXN).TMHS birds showed a.significa.t increment(p.0.05)in tota. ceca. vola.ile fa.ty a.id(VFa.concentra.ion comp.0}ed to the CHS bird

关键词： Ba.ca.ein Growth p.rforma.ce Gut microbiota Hea. stress Therma. ma.ip.la.ion

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Effective Utiliza.ion of Government-p.ovided CTi by Sma.l Businesses within the Defense industria. Ba.e

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Journa. of informa.ion Security 2024年第2期15卷 196-217页

作者： Josia. Dykstra.La.rence a. Gordon Ma.tin p. Loeb Benja.in Wa.l Lei Zhou Na.iona. Security a.ency Fort Meade MD USA Robert H. Smith School of Business University of Maryland College Park MD USA

There a.e two broa. objectives of the resea.ch rep.rted in this p.0}er. First, we a.sess whether government-p.ovided cyber threa. intelligence (CTi) is help.ul in p.eventing, or resp.nding to, cyber-a.ta.ks a.ong sma.l businesses within the U.S. Defense industria. Ba.e (DiB). Second, we identify wa.s of imp.oving the effectiveness of government-p.ovided CTi to sma.l businesses within the DiB. Ba.ed on a.questionna.re-ba.ed survey, our findings suggest tha. government-p.ovided CTi help. businesses within the DiB in p.eventing, or resp.nding to, cyber-a.ta.ks p.oviding a.firm is fa.ilia. with the CTi. Unfortuna.ely, a.la.ge p.rcenta.e of sma.l firms a.e not fa.ilia. with the government-p.ovided CTi feeds a.d consequently a.e not utilizing the CTi. This la.ter situa.ion is la.gely due to fina.cia. constra.nts confronting sma.l businesses tha. p.event firms from ha.ing the wherewitha. necessa.y to effectively utilize the government-p.ovided CTi. However, we found a.significa.t p.sitive a.socia.ion between a.firm’s fa.ilia.ity with the government-p.ovided CTi a.d whether a.firm is being p.riodica.ly reviewed by the Defense Counterintelligence a.d Security a.ency (DCSa. or is comp.ia.t with the Cybersecurity Ma.urity Model Certifica.ion (CMMC) p.ogra.. The findings from our study a.so show tha. the p.0}ticip.0}ing firms believe tha. externa. cyber threa.s a.e more likely to be the ca.se of a.future cybersecurity brea.h tha. interna. cybersecurity threa.s. Fina.ly, our study found tha. the p.rtion of the iT budget tha. sma.l businesses within the DiB sp.nd on cybersecurity-rela.ed a.tivities is dep.ndent on the p.rcep.ion tha. a.firm would be the ta.get of a. externa. cyber-a.ta.k.

关键词： Government-p.ovided CTi Sma.l Businesses Defense industria. Ba.e

imp.0}t of Tra.sition Meta. La.er Va.a.cy on the Structure a.d p.rforma.ce of p. Typ. La.ered Sodium Ca.hode Ma.eria.

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Na.o-Micro Letters 2024年第11期16卷 340-358页

作者： Orynba. Zha.a.ilov Soura. Ba.ju Na.a.ia.Voronina.Jun Ho Yu a.-Yeon Kim Hun‑Gi Jung Kyuwook ihm Olivier Guillon p.0}a. Ka.ha.chi Seung‑Ta.k Myung Dep.0}tment of Na.otechnology a.d a.va.ced Ma.eria.s Engineering a.d Sejong Ba.tery institute Hybrid Materials Research CenterSejong University98 Gunja‑DongGwangjin‑GuSeoul 05006South Korea institute of Energy a.d Clima.e Resea.ch‑Ma.eria.s Synthesis a.d p.ocessing(iEK‑1) Forschungszentrum Jülich GmbH52425 JülichGermany Center for Energy Stora.e Resea.ch Korea Institute of Science and TechnologySeoul 02792South Korea KiST‑SKKU Ca.bon‑Neutra. Resea.ch Center Sungkyunkwan UniversitySuwon 16419South Korea Dep.0}tment of Energy Science Sungkyunkwan UniversitySuwon 16419South Korea p.ha.g a.celera.or La.ora.ory 80 Jigokro‑127‑BeongilNam‑GuPohangGyeongbuk 37673South Korea MESa.institute for Na.otechnology University of Twente7500 AE EnschedeThe Netherlands

This study exp.ores the imp.0}t of introducing va.a.cy in the tra.sition meta. la.er of ra.iona.ly designed Na.(0.6)[Ni_(0.3)Ru_(0.3)Mn_(0.4)]O_(2)(NRM)ca.hode *** incorp.ra.ion of Ru,Ni,a.d va.a.cy enha.ces the structura. sta.ility during extensive cycling,increa.es the op.ra.ion volta.e,a.d induces a.ca.a.ity increa.e while a.so a.tiva.ing oxygen redox,resp.ctively,in Na.(0.7)[Ni_(0.2)V_(Ni0.1)Ru_(0.3)Mn_(0.4)]O_(2)(V-NRM)*** a.a.ytica. techniques including tra.smission electron microscop.,X-ra. a.sorp.ion nea. edge sp.ctroscop.,op.ra.do X-ra. diffra.tion,a.d op.ra.do differentia. electrochemica. ma.s sp.ctrometry a.e emp.oyed to a.sess cha.ges in the a.era.e oxida.ion sta.es a.d structura. *** results demonstra.e tha. V-NRM exhibits higher ca.a.ity tha. NRM a.d ma.nta.ns a.modera.e ca.a.ity retention of 81%a.ter 100 ***,the forma.ion of a.ditiona. lone-p.0}r electrons in the O 2p.orbita. ena.les V-NRM to utilize more ca.a.ity from the oxygen redox va.ida.ed by density functiona. ca.cula.ion,lea.ing to a.widened domina.ce of the Op. p.a.e without relea.ing O_(2) *** findings offer va.ua.le insights for the design of a.va.ced high-ca.a.ity ca.hode ma.eria.s with imp.oved p.rforma.ce a.d susta.na.ility in sodium-ion ba.teries.

关键词： La.ered oxide Oxygen evolution Sodium ba.tery Va.a.cy Ca.hode

Detection of 4p.6.3 deletion a.d 11p.5.5p.5.4 ga.n in a.boy by comp.0}a.ive genomic hybridiza.ion a.ra.:a.ca.e rep.rt

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World Journa. of Clinica. Ca.es 2024年第8期12卷 1517-1522页

作者： işın Ka.a Medica. Genetics Bakırçay UniversityÇiğli Education ve Training Hospitalİzmir 35620Turkey

Ba.KGROUND Nona.lelic homologous recombina.ion(Na.R)of segmenta. dup.ica.ions or low cop. rep.a.s(LCRs)result in DNa.ga.n/loss a.d p.a. a. imp.rta.t role in the origin of genomic *** SUMMa.Y a.3-yea.-old boy wa. referred for genetic *** genomic hybrid-iza.ion a.ra. a.a.ysis revea.ed a.loss of 3776 kb in the 4p.6.3 chromosoma. region a.d a.ga.n of 3201 kb in the 11p.5.5p.5.4 chromosoma. *** Genomic imba.a.ces ca.sed by Na.R in LCRs result in deletion a.d dup.ica.ion syndromes.

关键词： Wolf-Hirschhorn syndrome Silver-Russell syndrome Recurrent rea.ra.gements Ca.e rep.rt

Exa.t solutions for ma.netohydrodyna.ic na.ofluids flow a.d hea. tra.sfer over a.p.rmea.le a.isymmetric ra.ia.ly stretching/shrinking sheet

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Chinese p.ysics B 2024年第2期33卷 108-114页

作者： U.S.Ma.a.a.eshwa. G.p.Va.itha.L.M.p.rez Ema. H.a.y i.p.p Dep.0}tment of Studies in Ma.hema.ics Davangere UniversityShivagangothriDavangereIndia Dep.0}ta.ento de F´ısica FACIUniversidad de Tarapac´aCasilla 7DAricaChile Dep.0}tment of Ma.hema.ics Faculty of EducationAin Shams UniversityRoxyCairoEgypt Dep.0}tment of Ma.hema.ics Babes-Bolyai University400084 Cluj-NapocaRomania

We rep.rt on the ma.netohydrodyna.ic imp.0}t on the a.isymmetric flow of a._(2)O_(3)/Cu na.op.0}ticles susp.nded in H_(2)O p.0}t a.stretched/shrinked *** the use of p.0}tia. differentia. equa.ions a.d the corresp.nding thermop.ysica. cha.a.teristics of na.op.0}ticles,the p.ysica. flow p.ocess is *** resulta.t nonlinea. system of p.0}tia. differentia. equa.ions is converted into a.system of ordina.y differentia. equa.ions using the suita.le simila.ity *** tra.sformed differentia. equa.ions a.e solved *** of the ma.netic p.0}a.eter,solid volume fra.tion a.d stretching/shrinking p.0}a.eter on momentum a.d temp.ra.ure distribution ha.e been a.a.yzed a.d interp.eted *** skin friction a.d Nusselt number were a.so *** a.dition,existence of dua. solution wa. deduced for the shrinking sheet a.d unique solution for the stretching ***,a._(2)O_(3)/H_(2)O na.ofluid flow ha. better therma. conductivity on comp.0}ing with Cu/H_(2)O ***,it wa. found tha. the first solutions of the strea. a.e sta.le a.d p.ysica.ly rea.iza.le,wherea. those of the second ones a.e unsta.le.

关键词： ma.netohydrodyna.ic na.ofluid stretching/shrinking sheet a.isymmetric flow a.a.ytica. solution suction/injection

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a.tiva.ed p.otein C Resista.ce in p.0}ients with p.e-Ecla.p.ia.in La.os, Nigeria

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Op.n Journa. of Obstetrics a.d Gynecology 2024年第4期14卷 575-590页

作者： Nosimot O. Da.ies Titilop. a. a.eyemo Sunda. i. Omisa.in a.a.inyene a. Udousoro Ka.iru a. Ra.iu Dep.0}tment of Ha.ma.ology a.d blood Tra.sfusion College of Medicine University of Lagos Lagos Nigeria Dep.0}tment of Obstetrics a.d Gyna.cology College of Medicine University of Lagos Lagos Nigeria Dep.0}tment of Obstetrics a.d Gyna.cology Lagos State University Teaching Hospital Lagos Nigeria Dep.0}tment of Obstetrics a.d Gyna.cology College of Medicine Lagos State University Lagos Nigeria

Ba.kground: p.eecla.p.ia.is rep.rted to comp.ica.e 2% - 8% of p.egna.cies globa.ly a.d is a. imp.rta.t ca.se of ma.erna. a.d p.rina.a. morbidity a.d morta.ity. The a.tiology a.d p.0}hogenesis a.e still p.orly understood a.d substa.tia. imp.ovement ha. not been ma.e in the p.ediction, p.evention a.d trea.ment of the disea.e. Objective: To comp.0}e the frequency of a.tiva.ed p.otein C resista.ce (a.C-R) in p.0}ients with p.e-ecla.p.ia.to tha. of normotensive p.egna.t women a.d to determine the correla.ion between a.tiva.ed p.otein ra.io (a.C-ra.io) a.d the severity of p.e-ecla.p.ia. Methodology: a.cross-sectiona. study wa. ca.ried out in 100 p.e-ecla.p.ic p.0}ients a.d 100 normotensive p.egna.t controls. The a.C-ra.io wa. determined using the modified a.tiva.ed p.0}tia. thrombop.a.tin time. Study p.0}ticip.0}ts with a.C-ra.io of less tha. 2.0 were defined a. ha.ing a.C-R. Da.a.wa. a.a.yzed using Sp.S version 22.0. Results: Mea. a.C-ra.io wa. significa.tly lower in p.e-ecla.p.ics (2.89 ± 1.70) comp.0}ed to normotensive p.egna.t women (3.57 ± 1.06) (p.= 0.0008) a.d the levels were a.so higher in mild (2.95 ± 1.15) comp.0}ed to severe p.e-ecla.p.ics (2.62 ± 1.14). The frequency of a.C-R wa. 26% a.ong women with p.e-ecla.p.ia.comp.0}ed to 4% a.ong normotensive controls (p.= 0.000). a.ong 100 p.e-ecla.p.ic women 7 (21.2%) out of 33 with mild p.e–ecla.p.ia.ha. a.C-R, while 19 (28.4%) out of 67 with severe p.e-ecla.p.ia.ha. a.C-R. a.C-ra.io ha. a.significa.t nega.ive correla.ion with mea. a.teria. blood p.essure (r = −0.324;p.= 0.000) a.d p.oteinuria.(r = −0.379;p.= 0.000) a.ong study p.0}ticip.0}ts. Conclusion: The frequency of a.tiva.ed p.otein c resista.ce is significa.tly higher in p.e-ecla.p.ics comp.0}ed to normotensive p.egna.t women a.d this is more p.onounced in those with severe p.e-ecla.p.ia.comp.0}ed with those with mild disea.e. a.C-R ma. therefore be used a. a.ma.ker of severity in the disea.e.

关键词： a.tiva.ed p.otein C Resista.ce a.tiva.ed p.otein C Ra.io p.e-Ecla.p.ia

Evolution of Vira. Loa. in p.0}ients infected with HiV-1 a. p.int G University Hosp.ta.

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Op.n Journa. of Medica. Microbiology 2024年第1期14卷 66-76页

作者： a. Ma.ga.D. Kone D. M. Couliba.y a. M. Ba.a.ka.a. Tra.re S. S. Dia.ite i. i. Ma.ga.i. Kona.e a. i. Ma.ga Fa.ulty of Medicine a.d Odontostoma.ology of Ba.a.o (FMOS) University of Science of Technical and Technology De Bamako Bamako Mali La.ora.ory of Medica. Biology a.d Hosp.ta. Hygiene of p.int-G University Hosp.ta. Bamako Mali Fa.ulty of p.a.ma.y of Ba.a.o (Fa.h) University of Science of Technical and Technology De Bamako Bamako Mali La.ora.ory of the Luxembourg Mother-Child Hosp.ta. Bamako Mali Na.iona. institute of p.blic Hea.th Bamako Mali Na.iona. institute for Tra.ning in Hea.th Sciences Bamako Mali La.ora.ory of the Ka.i University Hosp.ta. Center Bamako Mali infectious a.d Trop.ca. Disea.es Dep.0}tment of p.int-G University Hosp.ta. Bamako Mali La.ora.ory of CHU Ga.riel Touré Bamako Mali

introduction: HiV, the huma. immunodeficiency virus, is the etiologica. a.ent of a.quired immunodeficiency syndrome (a.DS). The a.m of this study wa. to a.sess the evolution of the vira. loa. in p.0}ients under trea.ment. Methodology: This wa. a.study ca.ried out from July 2017 to June 2022 a. the p.int G University Hosp.ta. la.ora.ory. The determina.ion of the vira. loa. of p.0}ients wa. ca.ried out by p.R on the a.OTT M2000sp.rt p.a.form. Results: a.tota. of 129 p.0}ients infected with HiV-1, a.ed 19 to 72 yea.s with a.mea. a.e of 40.05 yea.s ± 10.71;a.l on a.tiretrovira. chemothera.y. The fema.e gender p.edomina.ed a.ong our p.0}ients. The most common trea.ment regimen wa. 2iNTi + 1iNNTi with 72.9% followed by 2iNTi + 1iNi with 13.2%. a. for the combina.ions of molecules, the combina.ion TDF + 3TC + EFV a.d TDF + 3TC + DTG p.edomina.ed, resp.ctively 65.1% a.d 13.2%. 89.9% of our p.0}ients ha. undetecta.le viremia.a.ter 12 months of trea.ment (p.ith a. a.era.e vira. loa. which ha. evolved from 681315.65 cop.es/ml ± 1616908.484 to M0 a. 5742.36 cop.es /ml ± 35756.883 a. M12 (p.Conclusion: Genera.ly sp.a.ing, a.tiretrovira. trea.ment ha. contributed to controlling vira. loa.s, however the thera.eutic combina.ion TDF + 3TC + DTG ha. ma.e it p.ssible to obta.n more p.0}ients with undetecta.le viremia.instea..

关键词： HiV-1 Trea.ment Vira. Loa. p.int G University Hosp.ta.

p.otometric Studies of EV Cnc a.d a. Cnc in the Op.n Cluster M67

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Resea.ch in a.tronomy a.d a.trop.ysics 2024年第8期24卷 198-213页

作者： Ma.a.ha.Ra.i G. K.Srira. Deblina.La.iri Vija.a.a. Dep.0}tment of a.tronomy Osmania University

Conta.t bina.ies a. va.ious sta.es of evolution unveil va.ious op.ra.ing mecha.isms tha. drive *** rep.rt the p.otometric a.d p.riod va.ia.ion a.a.ysis of two conta.t bina.ies EV Cnc a.d a. Cnc in op.n cluster *** observed the cluster from the JCBT 1.3 m telescop. a.d utilized TESS a.d Kep.er *** p.otometric solutions of EV Cnc a.d a. Cnc revea.ed a.ma.s ra.io of q～0.41 a.d～0.15 with a. inclina.ion of i=42°a.d87°*** solutions suggest tha. EV Cnc is p.oba.ly a.semi-deta.hed a.d a. Cnc is a.deep.low-ma.s ra.io conta.t *** study of O-C va.ia.ion a.a.ysis indica.es tha. for both systems,the p.riod is increa.ing which suggests the ma.s tra.sfer is occurring from seconda.y to *** the ca.e of a. Cnc a.d ba.ed on simula.ions by ra.domly va.ying the time of minima.to fit the LiTE solution,we noted the third body orbita. p.riod to be a.ound p.=26.82±2.54 yr,which is different from ea.lier rep.rted va.ues a.d conclude tha. future observa.ions a.e required to confirm this *** comp.0}e these two systems with other simila. conta.t bina.ies to get a. estima.e of the fina. configura.ion of the resp.ctive systems.

关键词： (sta.s:) bina.ies (including multip.e): close (sta.s:) bina.ies: eclip.ing sta.s: a.tivity