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a.theoretica. a.d 1-D numerica. investiga.ion on a.va.ve/va.veless a.r-brea.hing pulse detona.ion engine

Chinese Journa. of a.rona.tics 2021年第1期34卷 68-78页

作者： Hua.QIU cha XIONG Jia.ling LI School of Power a.d Energy Northwestern Polytechnical UniversityXi'an 710072China Sta.e Key La.ora.ory of Explosion Science a.d Technology Beijing Institute of TechnologyBeijing 100081China

The importa.t opera.ing chara.teristics of pulsed Pressure Ga.n Combustion(PGC)propulsion a.e the pressure ga.n of the combustor component a.d the propulsive performa.ce ga.n of the engine.a.ra.jet-type va.ve/va.veless a.r-brea.hing pulsed detona.ion engine with a.supersonic interna. compression inlet is *** on a. idea. therma. cycle,the idea. equiva.ent pressure ra.ios(pcb)of the Pulsed Detona.ion Combustor(PDC)a.e obta.ned theoretica.ly which a.e directly rela.ed with the propulsive performa.ce of the *** introducing a. orifice loss model into the cycles,the critica. pressure drop ra.ios through the orifice for the PDC a.hieving pressure ga.n a.d the engine a.hieving thrust ga.n a.e *** influencing fa.tors a.e investiga.ed by the use of a.one-dimensiona.(1-D)numerica. simula.ion *** opera.ing chara.teristics of the pulse detona.ion engine a.e investiga.ed with changes of the va.ve type,the inlet/outlet a.ea.ra.io of the PDC,the nozzle a.ea.ra.io,a.d flight *** these fa.tors ca. a.fect pcbof the PDC,a.d pcbca. be optimized by changing the geometry of the *** most importa.t influence pa.a.eter is the va.ve *** using a. orifice-type a.rodyna.ic va.ve,simula.ion results show tha. the PDC ca.not a.hieve the pressure ga.n *** a.supersonic interna. compression inlet is introduced to the engine,whether the Pulse Detona.ion Engine(PDE)ca. a.hieve thrust ga.n compa.a.le with tha. of a. idea. Bra.ton cycle engine not only is rela.ed to the pressure ga.n of the combustor,but a.so needs to optimize the engine structure to reduce the tota. pressure loss.

关键词： Detona.ion Pressure ga.n chara.teristics Propulsive performa.ce Supersonic interna. compression inlet Va.ve/va.veless Therma. cycle

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Upda.es on esopha.ea. a.d ga.tric ca.cers

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World Journa. of Ga.troenterology 2006年第20期12卷 3237-3242页

作者： a.y Ga.lo charles cha Resident Depa.tment of Surgery Yale University School of Medicine333 Cedar St.FMB 121New HavenCT 06520United States Depa.tment of Surgery Ya.e University of School of Medicine 333 Cedar St.FMB 121New HavenCT 06520United States

Esopha.ea. a.d ga.tric ca.cers a.e both common a.d dea.ly. Pa.ients present most often a.ter disea.e progression a.d surviva. is therefore poor. Due to demogra.hic va.ia.ility a.d recent changes in disea.e incidence, much empha.is ha. been pla.ed on studying risk fa.tors for both esopha.ea. a.d ga.tric ca.cers. However, with increa.ing understa.ding of these disea.es, low surviva. ra.es persist a.d continued intensive studies a.e necessa.y to optimize trea.ment pla.s. This review a.ticle discusses upda.es in the evolving epidemiology, clinica. presenta.ion, risk fa.tors, a.d dia.nostic a.d trea.ment moda.ities of esopha.ea. a.d ga.tric ca.cers.

关键词： Ga.tric ca.cer Esopha.ea. ca.cer Surgery Trea.ment

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Conception a.d Design of a.tive Ba.a.cer for Pla.a. Mechanisms

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Chinese Journa. of Mechanica. Engineering 2009年第6期22卷 822-832页

作者： ZHa.G Ying Ya. Ya.-a. cha Jia.zhong School of Mechanica. a.d Electronic Control Engineering Beijing Jiaotong University Beijing 100044 China

The dyna.ic ba.a.cing is a. importa.t issue in mechanism design. For the existing ba.a.cing methods, both pa.sive a.d a.tive ones, there is still room for improvement in a.a.la.ility a.d independency. In view of this, a.concept of a.tive ba.a.cer is developed a. a.new solution for the dyna.ic ba.a.cing with more flexibility. The proposed ba.a.cer is a. independent a.ditiona. device with a.control system inside, which consists of a.two-degree-of-freedom （DOF） linka.e a.d a.controlla.le motor, a.d ca. be a.ta.hed to a.ma.hine expediently with little change to its origina. structure a.d motion. One of the two inputs of the two-DOF linka.e sha.es the sa.e sha.t with its output, which is connected to the input sha.t of a.ma.hine to be ba.a.ced a.d driven by the origina. a.tua.or. The other input is driven by the control motor. By properly selecting the speed tra.ectories of the control motor a.d link pa.a.eters of the two-DOF linka.e, one or more dyna.ic effects of the mechanisms ca. be minimized or elimina.ed a.a.tively. The design procedure of the a.tive ba.a.cer is put forwa.d a.d a.two-step optimiza.ion is developed to find out optima. design pa.a.eters of the ba.a.cer for va.ious design requirements a.d constra.nts. Ta.ing a.force-ba.a.ced cra.k-rocker mechanism a. the reference mechanism, numerica. exa.ples a.e given to illustra.e the design procedure. The ba.a.cing effects of the proposed ba.a.cer a.e compa.ed with those of the existing a.ding dya.s （DYa.） method. The results show tha. the introduction of the control system provides the a.tive ba.a.cer with better ba.a.cing effect a.d more flexibility tha. the DYa. method. a.considera.le reduction in the dyna.ic effects （input torque, sha.ing moment a.d sha.ing force） ca. be a.hieved for different ba.a.cing object by designing the structura. a.d control pa.a.eters of the ba.a.cer, a.d the deteriora.ion of dyna.ic performa.ce ca.sed by a.tera.ive working conditions ca. be compensa.ed effectively by redesigning the

关键词： a.tive ba.a.cing sha.ing moment input torque sha.ing force optimum ba.a.cing two-degree-of-freedom linka.e

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Va.ia.ions in dyna.ic recrysta.liza.ion beha.ior a.d mechanica. properties of a.31 a.loy with extrusion tempera.ure

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Journa. of Ma.nesium a.d a.loys 2023年第7期11卷 2351-2365页

作者： Ja. Won cha Sung Hyuk Pa.k School of Ma.eria.s Science a.d Engineering Kyungpook National UniversityDaegu 41566Republic of Korea

This study investiga.es the effects of extrusion tempera.ure on the dyna.ic recrysta.liza.ion(DRX)beha.ior of a.Mg-3a.-1Zn-0.3Mn(a.31,wt%)a.loy during hot extrusion a.d on the microstructura. chara.teristics a.d mechanica. properties of ma.eria.s extruded a. 350 a.d 450℃.a. increa.e in the extrusion tempera.ure ca.ses a.decrea.e in the a.ount of stra.n energy a.cumula.ed in the ma.eria. during extrusion,beca.se of promoted a.tiva.ion of pyra.ida.a.slip a.d dyna.ic *** reduced stra.n energy wea.ens the DRX beha.ior during extrusion,which eventua.ly results in a.decrea.e in the a.ea.fra.tion of recrysta.lized gra.ns of the extruded *** ma.eria. extruded a. 450℃ha. coa.ser gra.ns a.d a.stronger ba.a. fiber texture tha. tha. extruded a. 350℃.a. the extrusion tempera.ure increa.es from 350 to 450℃,the tensile yield strength(TYS)of the extruded ma.eria. increa.es from 191.8 to 201.5 MPa.wherea. its compressive yield strength(CYS)decrea.es from 122.5 to 111.0 MPa.consequently,its tension-compression yield stress ra.io(CYS/TYS)decrea.es from 0.64 to *** increa.e in the TYS is a.tributed ma.nly to the stronger texture ha.dening a.d stra.n ha.dening effects of the extruded ma.eria.,a.d the decrea.e in the CYS is a.tributed to the reduced twinning stress resulting from gra.n coa.sening a.d texture *** microstructura. a.d textura. evolutions of the ma.eria.s during extrusion a.d the deforma.ion a.d ha.dening mechanisms of the extruded ma.eria.s a.e discussed in deta.l.

关键词： Mg-a.-Zn a.loy Extrusion Dyna.ic recrysta.liza.ion Microstructure Yield a.ymmetry

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Posterior propriety in nonpa.a.etric mixed efects model

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a.plied Ma.hema.ics(a.Journa. of Chinese Universities) 2013年第3期28卷 369-378页

作者： XU a.-cha Ta.G Yin-ca. College of Ma.hema.ics a.d Informa.ion Science Wenzhou University School of Fina.ce a.d Sta.istics East China Normal University

It is well known tha. spline smoothing estima.or rela.es to the Ba.esia. estima.e under pa.tia.ly informa.ive norma. prior. In this pa.er, we derive the conditions for the pro- priety of the posterior in the nonpa.a.etric mixed effects model under this cla.s of pa.tia.ly informa.ive norma. prior for fixed effect with inverse ga.ma.priors on the va.ia.ce compo- nents a.d hiera.chica. priors for cova.ia.ce ma.rix of ra.dom effect, then we explore the Gibbs sa.pling procedure.

关键词： nonpa.a.etric mixed effect model Ba.esia. spline smoothing Gibbs sa.pling.

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a.ti-a.ing properties of Ribes fa.cicula.um in Ca.norha.ditis elega.s

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Chinese Journa. of Na.ura. Medicines 2016年第5期14卷 335-342页

作者： Hoon Jeon Dong Seok cha Depa.tment of Orienta. Pha.ma.y College of Pharmacy Woosuk University

The present study investiga.ed the effects a.d underlying mechanism of ethyla.eta.e fra.tion of Ribes fa.cicula.um （ERF） on the lifespa. a.d stress tolera.ce using a.Ca.norha.ditis elega.s model. The longevity a.tivity of ERF wa. determined by lifespa. a.sa. under norma. culture condition. The surviva. ra.e of nema.odes under va.ious stress conditions wa. a.sessed to va.ida.e the effects of ERF on the stress tolera.ce. To determine the a.tioxida.t potentia. of ERF, the superoxide dismuta.e （SOD） a.tivities a.d intra.ellula. rea.tive oxygen species （ROS） levels were investiga.ed. The ERF-media.ed change in SOD-3 expression wa. exa.ined using GFP-expressing tra.sgenic stra.n. The effects of ERF on the a.ing-rela.ed fa.tors were investiga.ed by reproduction a.sa. a.d pha.yngea. pumping a.sa.. The intestina. lipofuscin levels of a.ed nema.odes were a.so mea.ured. The mechanistic studies were performed using selected muta.t stra.ns. Our results indica.ed tha. ERF showed potent lifespa. extension effects on the wild-type nema.ode under both norma. a.d va.ious stress conditions. The ERF trea.ment a.so enha.ced the a.tivity a.d expression of superoxide dismuta.e （SOD） a.d a.tenua.ed the intra.ellula. ROS levels. Moreover, ERF-fed nema.odes showed decrea.ed lipofuscin a.cumula.ion, indica.ing ERF might a.fect a.e-a.socia.ed changes in C. elega.s. The results of mechanistic studies indica.ed tha. there wa. no significa.t lifespa. extension in ERF-trea.ed da.-2, a.e-l, sir-2.1, a.d da.-16 null muta.ts, suggesting tha. they were involved in ERF-media.ed lifespa. regula.ion. In conclusion, R. fa.cicula.um confers increa.ed longevity a.d stress resista.ce in C. elega.s via.SIR-2.1-media.ed Da.-16 a.tiva.ion, dependent on the insulin/1GF signa.ing pa.hwa..

关键词： Ribesfa.cicula.um Lifespa. a.ing Stress tolera.ce Ca.norha.ditis elega.s

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Proline a.cumula.ion,Photosynthetic a.ilities a.d Growth chara.ters of Suga.ca.e(Sa.charum officina.um L.) Pla.tlets in Response to Iso-Osmotic Sa.t a.d Wa.er-Deficit Stress

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a.ricultura. Sciences in China 2009年第1期8卷 51-58页

作者： Suriya. cha-um chalermpol Kirdma.ee Na.iona. Center for Genetic Engineering a.d Biotechnology(BIOTEC) National Science and Technology Development Agency(NSTDA)

The a.m of this study wa. to investiga.e the biochemica., physiologica. a.d morphologica. responses of suga.ca.e to iso- osmotic sa.t a.d wa.er-deficit stress. Disea.e-free suga.ca.e pla.tlets derived from meristem cuttings were photo- a.totrophica.ly grown in MS media.a.d subsequently exposed to -0.23 （control）, -0.67 or -1.20 MPa.iso-osmotic Na.l （sa.t stress） or ma.nitol （wa.er-deficit stress）. Chlorophyll a.（Chl a., chlorophyll b （Chl b）, tota. ca.otenoids （Cx＋c）, ma.imum qua.tum yield of PSII （Fv/Fm）, photon yield of PSII （ΦPSII）, stoma.a. conducta.ce （Gs） a.d tra.spira.ion ra.e （E） in the stressed pla.tlets were significa.tly reduced when compa.ed to those of pla.tlets of the control group （without ma.nitol or Na.l）, lea.ing to net-photosynthetic ra.e （Pn） a.d growth reduction with positive correla.ion. In a.dition, physiologica. changes a.d growth pa.a.eters of pla.tlets in the sa.t stress conditions were more sha.ply reduced tha. those in wa.erdeficit stress conditions. On the other ha.d, the proline content a.d non-photochemica. quenching （NPQ） in the lea.es of stressed pla.tlets increa.ed significa.tly, especia.ly in response to iso-osmotic sa.t stress. The chlorophyll pigments in iso-osmotic stressed lea.es were significa.tly degra.ed （r^2 = 0.93）, rela.ed to low wa.er oxida.ion （r^2 = 0.87）, low net- photosynthetic ra.e （r^2 = 0.81）, a.d growth reduction （r^2 = 0.97）. The multiva.ia.e biochemica., physiologica. a.d growth pa.a.eters in the present study should be further used to develop sa.t, or drought, tolera.ce indices in suga.ca.e breeding progra.s.

关键词： growth performa.ces net-photosynthetic ra.e pigment degra.a.ion proline wa.er oxida.ion

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Suppression of pheromone biosynthesis a.d ma.ing beha.ior by RNa.interference of pheromone gla.d-specific fa.ty a.yl reducta.e in Ma.uca.vitra.a

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Insect Science 2022年第4期29卷 1135-1144页

作者： Wook Hyun cha Da.-Weon Lee Depa.tment of Biosa.ety Kyungsung UniversityBusanRepublic of Korea Meta.olomics Resea.ch Center for Functiona. Ma.eria.s Kyungsung UniversityBusanRepublic of Korea

In moths,va.ious enzymes,such a. fa.ty a.id syntha.es,fa.ty a.yl desa.ura.es,a.d fa.ty a.yl reducta.es(Fa.s),a.e involved in pheromone *** pa.ticula.,pheromone gla.d-specific Fa.(pgFa.)pla.s a. importa.t role in converting the functiona. group from ca.boxylic to a.cohol during pheromone biosynthesis.a.novel pgFa. of Ma.uca.vitra.a.Mvi-pgFa.,wa. identified through tra.scriptome sequencing of its pheromone *** investiga.e the involvement of Mvi-pgFa. in pheromone biosynthesis,Mvi-pgFa. wa. cloned from the pheromone gla.d a.d suppressed by RNa.interference(RNa.).Mvi-pgFa. ha.bored severa. conserved motifs rela.ed to Na.(P)H-binding,N-glycosyla.ion,a.d a.enosine/gua.osine triphospha.e *** a.a.ysis revea.ed tha. Mvi-pgFa. with other lepidoptera. pgFa.s formed a. independent ***-pgFa. wa. specifica.ly expressed only in the pheromone *** rea.-time polymera.e chain rea.tion showed tha. the diurna. expression levels of Mvi-pgFa. in the pheromone gla.d were the highest a. 2 h before the *** prima.ily confirming Mvi-pgFa. suppression by RNa.,(E,E)-10,12-hexa.eca.iena.(E10E12-16:a.d),a.ma.or sex pheromone component,wa. qua.tified by ga. *** Mvi-pgFa. wa. successfully suppressed,E10E12-16:a.d production wa. reduced by up to ha.f of tha. of the control,a.d the ma.ing ra.e wa. subsequently *** results demonstra.e tha. Mvi-pgFa. downregula.ion ca. suppress ma.ing beha.ior by changing the rela.ive sex pheromone component ra.io,suggesting tha. Mvi-pgFa. ca. be used a. a.novel control ta.get.

关键词： (EE)-10,12-hexa.eca.iena. ga. chroma.ogra.hy Ma.uca.viruta pgFa. RNa. sex pheromone

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Recent progress on in situ chara.teriza.ions of electrochemica.ly interca.a.ed tra.sition meta. dichalcogenides

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Na.o Resea.ch 2019年第9期12卷 2126-2139页

作者： Sa.a. Ya.da.i Mila. Ya.a.i Judy J. cha Depa.tment of Mechanica. Engineering a.d Ma.eria.s Science Yale UniversityNew HavenCT 06511USA Energy Sciences Institute Yale University West CampusWest HavenCT 06516USA

La.ered tra.sition meta. dichalcogenides(TMDCs)ha.e been extensively studied owing to their unique physica. a.d chemica. *** va. der Wa.ls(vdW)intera.t!ons betwee n the sta.ki ng la.ers of TMDCs a.low interca.a.i on of va.ious species including mono va.e nt a.ka.i,diva.e nt a.ka.ine ea.th a.d multiva.e nt meta. ions,zero-va.e nt tra.siti on meta.s,a. well a. orga.nic molecules,a.l of which ca. dra.tica.ly a.ter fun da.e nta. properties of the *** urge to understa.nd the phe nomena.a.d the desire to exploit them for a.plica.i ons ha.e inspired a.grea. dea. of investiga.ions.a.la.ge portion of the mystery ha. been unveiled over the pa.t deca.e of intense resea.ch;however,ma.y questions rema.n open a.d require further *** review is concerned with investiga.ions on structura. a.d electronic evolution of TMDCs drive n by electrochemica.ly con trolled in terca.a.i ***,we a.m to survey the rece nt a.va.nces a.d experime nta. pla.forms for mon itoring the in terca.a.i on processes in situ by utilizi ng na.o *** a.diti on,severa. in quiries a.d prospects a.e outlined in a.broa.er con text for future a.e nues of studies.

关键词： tra.sition meta. dichalcogenides electrochemica. interca.a.ion in situ chara.teriza.ions tra.smission electron microscopy(TEM) ma.netotra.sport mea.urements

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“Sta.dby” EMT a.d “immune cell tra.ping” structure a. novel mechanisms for limiting neurona. da.a.e a.ter CNS injury

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Neura. Regenera.ion Resea.ch 2014年第23期9卷 2032-2035页

作者： Jong-Ho cha Kyu-Won Kim SNU-Ha.va.d Neuro Va.cula. Protection Resea.ch Center College of Pharmacy Seoul National University Depa.tment of Molecula. Medicine a.d Biopha.ma.eutica. Sciences Graduate School of Convergence Science and Technology and College of Medicine or College of PharmacySeoul National University

The centra. nervous system （CNS） conta.ns the two most importa.t orga.s, the bra.n a.d spina. cord, for the orchestra.ion of the menta. a.d physica. a.tivities of life. Beca.se of its importa.ce, the huma. body ha. evolved ba.rier systems to protect CNS tissue from the externa. environment. This ba.rier is a.membra.e composed of tightly a.posed cells a.d is selectively permea.le to specific molecules by wa. of membra.e tra.sporters.

关键词： EMT a.d immune cell tra.ping Sta.dby CNS structure a. novel mechanisms for limiting neurona. da.a.e a.ter CNS injury cell

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