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Communications in Theoretical Physics 2020年第1期72卷 66-80页

作者： a d alhaidari Saudi Center for Theoretical Physics PO Box 32741Jeddah 21438Saudi Arabia

We present a formulation of quantum mechanics based on the theory of orthogonal *** wavefunction is expanded over a complete set of square integrable basis where the expansion coefficients are orthogonal polynomials in the energy and physical *** about the corresponding physical systems(both structural and dynamical)are derived from the properties of these *** demonstrate that an advantage of this formulation is that the class of exactly solvable quantum mechanical problems becomes larger than in the conventional formulation(see,for example,table 3 in the text).We limit our investigation in this work to the Askey classification scheme of hypergeometric orthogonal polynomials and focus on the Wilson polynomial and two of its limiting cases(the Meixner–Pollaczek and continuous dual Hahn polynomials).Nonetheless,the formulation is amenable to other classes of orthogonal polynomials.

关键词： tridiagonal representation orthogonal polynomials recursion relation asymptotics energy spectrum phase shift

Reconstructing the Potential Function in a Formulation of Quantum Mechanics Based on Orthogonal Polynomials

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Communications in Theoretical Physics 2017年第12期67卷 711-728页

作者： A.d.alhaidari Saudi Center for Theoretical Physics

In a recent reformulation of quantum mechanics, the properties of the physical system are derived from orthogonal polynomials that make up the expansion coefficients of the wavefunction in a complete set of square integrable basis. Here, we show how to reconstruct the potential function so that a correspondence with the standard formulation could be established. However, the correspondence places restriction on the kinematics of such problems.

关键词： wavefunction potential function orthogonal polynomials recursion relation tridiagonal representations asymptotics

Solution of Spin and Pseudo-Spin Symmetric dirac Equation in (1＋1) Space-Time Using Tridiagonal Representation Approach

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Communications in Theoretical Physics 2018年第3期69卷 241-256页

作者： I.A.Assi A.d.alhaidari H.Bahlouli department of Physics and Physical Oceanography Memorial University of Newfoundland St. John's NL A1B3XT Canada Saudi Center for Theoretical Physics P.O. Box 32741 Jeddah 21438 Saudi Arabia Physics department King Fahd University of Petroleum & Minerals Dhahran 31261 Saudi Arabia

The aim of this work is to find exact solutions of the dirac equation in(1+1) space-time beyond the already known *** consider exact spin(and pseudo-spin) symmetric dirac equations where the scalar potential is equal to plus(and minus) the vector *** also include pseudo-scalar potentials in the *** spinor wavefunction is written as a bounded sum in a complete set of square integrable basis,which is chosen such that the matrix representation of the dirac wave operator is tridiagonal and *** makes the matrix wave equation a symmetric three-term recursion relation for the expansion coefficients of the *** solve the recursion relation exactly in terms of orthogonal polynomials and obtain the state functions and corresponding relativistic energy spectrum and phase shift.

关键词： dirac equation spin and pseudo-spin tridiagonal representations recursion relation orthogonal polynomials

Energy Spectrum for a Short-Range 1/r Singular Potential with a Non-Orbital Barrier Using the Asymptotic Iteration Method

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Journal of Applied Mathematics and Physics 2016年第1期4卷 79-85页

作者： Abdullah J. Sous Abdulaziz d. alhaidari Faculty of Technology and Applied Sciences Al-Quds Open University Tulkarm Palestine Saudi Center for Theoretical Physics Jeddah Saudi Arabia

Using the asymptotic iteration method, we obtain the S-wave solution for a short-range three-parameter central potential with 1/r singularity and with a non-orbital barrier. To the best of our knowledge, this is the first attempt at calculating the energy spectrum for this potential, which was introduced by H. Bahlouli and A. d. alhaidari and for which they obtained the “potential parameter spectrum”. Our results are also independently verified using a direct method of diagonalizing the Hamiltonian matrix in the J-matrix basis.

关键词： Short-Range Three-Parameter Central Potential Asymptotic Iteration Method Potential Parameter Spectrum Method J-Matrix diagonalizing Method Energy Eigenvalues

Biochemical dissection of STAT3 signaling in amyotrophic lateral sclerosis

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Neural Regeneration Research 2025年第11期20卷 3229-3230页

作者： Savina Apolloni Nadia d’Ambrosi department of Biology University of Rome Tor VergataRomeItaly

Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disease characterized by the loss of upper and lower motor neurons,clinically marked by muscle atrophy and *** the clinical course is highly variable,the average time from the onset of symptoms to the need for respiratory support or death is 3-5 *** is the most prevalent motor neuron disease in adults,occurring at a rate of 2 per 100,000 individuals and affecting 5.4 per 100,000 individuals overall.

关键词： STAT3 dissection sclerosis

Anti-amyloid antibodies in Alzheimer’s disease: what did clinical trials teach us?

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Neural Regeneration Research 2025年第4期20卷 1092-1093页

作者： danko Jeremic Lydia Jiménez-díaz Juan d.Navarro-López NeuroPhysiology&Behavior Lab University of Castilla-La ManchaBiomedical Research Center(CRIB)School of Medicine of Ciudad RealCiudad RealSpain

Although many causes of Alzheimer’s disease(Ad)may exist,both the original amyloid cascade and tau hypotheses posit that abnormal misfolding and accumulation of amyloid-β(Aβ)and tau protein is the central event causing the ***,that conclusion could be only partly true,and there is conflicting evidence about the role of both proteins in Ad,being able to precede and influence one *** researchers argue that these proteins are mere executors rather than primary causes of ***,there have been continuing refinements of both hypotheses,with alternative explanations proposed.Aβand tau proteins may be independently involved in specific neurotoxic pathways;yet there may be other crucial processes going on in early ***,accumulating evidence suggests that Aβand tau act synergistically,rather than additively in disease onset(Jeremic et al.,2021,2023a).

关键词： amyloid Alzheimer additive

Remaking a connection:molecular players involved in post-injury synapse formation

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Neural Regeneration Research 2025年第6期20卷 1719-1720页

作者： diogo Tomé Ramiro d.Almeida iBiMEd-Institute of Biomedicine Department of Medical SciencesUniversity of AveiroAveiroPortugal CNC-Center for Neuroscience and Cell Biology University of CoimbraCoimbraPortugal

Functional recovery from central nervous system(CNS)trauma depends not only on axon regeneration or compensatory sprouting of uninjured fibers but also on the ability of newly grown axons to establish functional synapses with appropriate *** several studies have successfully promoted long-distance axonal regeneration in distinct CNS injury models,none of them have resulted in a viable therapeutic approach for patient recovery.A possible reason may be the lack of new synaptogenesis for reestablishing the circuitry lost after ***,we discuss how our understanding of the mechanisms that instruct synapse formation in the injured nervous system may contribute to the design of new strategies to promote functional restoration in traumatic CNS disorders.

关键词： viable injury instru

Automatic Channel detection Using dNN on 2d Seismic data

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Computer Systems Science & Engineering 2021年第1期36卷 57-67页

作者： Fahd A.alhaidari Saleh A.Al-dossary Ilyas A.Salih Abdlrhman M.Salem Ahmed S.Bokir Mahmoud O.Fares Mohammed I.Ahmed Mohammed S.Ahmed Imam Abdulrahman Bin Faisal University College of Computer Science and Information TechnologyDammam34212Saudi Arabia Saudi Aramco Oil Company EXPEC-IIDhahranSaudi Arabia

Geologists interpret seismic data to understand subsurface properties and subsequently to locate underground hydrocarbon *** are among the most important geological features interpreters analyze to locate petroleum ***,manual channel picking is both time consuming and ***,similar to any other process dependent on human intervention,manual channel picking is error prone and *** address these issues,automatic channel detection is both necessary and important for efficient and accurate seismic *** systems make use of real-time image processing techniques for different *** channel detection is a combination of different mathematical methods in digital image processing that can identify streaks within the images called channels that are important to the oil *** this paper,we propose an innovative automatic channel detection algorithm based on machine learning *** new algorithm can identify channels in seismic data/images fully automatically and tremendously increases the efficiency and accuracy of the interpretation *** algorithm uses deep neural network to train the classifier with both the channel and non-channel *** provide a field data example to demonstrate the performance of the new *** training phase gave a maximum accuracy of 84.6%for the classifier and it performed even better in the testing phase,giving a maximum accuracy of 90%.

关键词： deep neural networks deep learning channel detection image processing two-dimensional seismic data

Treating amyotrophic lateral sclerosis with allogeneic Schwann cell-derived exosomal vesicles: a case report

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Neural Regeneration Research 2025年第4期20卷 1207-1216页

作者： Pascal J.Goldschmidt-Clermont Aisha Khan George Jimsheleishvili Patricia Graham Adriana Brooks Risset Silvera Alexander J.P.Goldschmidt damien d.Pearse W.dalton dietrich Allan d.Levi James d.Guest Miller School of Medicine University of MiamiMiamiFLUSA Stem Cell Institute Miller School of MedicineUniversity of MiamiMiamiFLUSA The Miami Project to Cure Paralysis Miller School of MedicineUniversity of MiamiMiamiFLUSA Alzady International LLC MiamiFLUSA Neurological Surgery Miller School of MedicineUniversity of MiamiMiamiFLUSA

Schwann cells are essential for the maintenance and function of motor neurons,axonal networks,and the neuromuscular *** amyotrophic lateral sclerosis,where motor neuron function is progressively lost,Schwann cell function may also be ***,important signaling and potential trophic activities of Schwann cell-derived exosomal vesicles have been *** case report describes the treatment of a patient with advanced amyotrophic lateral sclerosis using serial intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles,marking,to our knowledge,the first instance of such *** 81-year-old male patient presented with a 1.5-year history of rapidly progressive amyotrophic lateral *** initial diagnosis,the patient underwent a combination of generic riluzole,sodium phenylbutyrate for the treatment of amyotrophic lateral sclerosis,and *** patient volunteered to participate in an FdA-approved single-patient expanded access treatment and received weekly intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles to potentially restore impaired Schwann cell and motor neuron *** confirmed that cultured Schwann cells obtained from the amyotrophic lateral sclerosis patient via sural nerve biopsy appeared impaired(senescent)and that exposure of the patient’s Schwann cells to allogeneic Schwann cell-derived exosomal vesicles,cultured expanded from a cadaver donor improved their growth capacity in *** a period of observation lasting 10 weeks,during which amyotrophic lateral sclerosis Functional Rating Scale-Revised and pulmonary function were regularly monitored,the patient received weekly consecutive infusions of 1.54×1012(×2),and then consecutive infusions of 7.5×1012(×6)allogeneic Schwann cell-derived exosomal vesicles diluted in 40 mL of dulbecco’s phosphate-buffered *** of the infusions were associated with adverse events such as infusion reactions(allergic or otherwise)or

关键词： allogeneic amyotrophic lateral sclerosis exosomes infusion neuromuscular junction Schwann cell

Oligodendroglial heterogeneity in health,disease,and recovery:deeper insights into myelin dynamics

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Neural Regeneration Research 2025年第11期20卷 3179-3192页

作者： Pieter-Jan Serneels Julie d.de Schutter Lies de Groef Lieve Moons Steven Bergmans KU Leuven Leuven Brain InstituteDepartment of BiologyAnimal Physiology and Neurobiology DivisionNeural Circuit Development&Regeneration Research GroupLeuvenBelgium KU Leuven Leuven Brain InstituteDepartment of BiologyAnimal Physiology and Neurobiology DivisionCellular Communication&Neurodegeneration Research GroupLeuvenBelgium

decades of research asserted that the oligodendroglial lineage comprises two cell types:oligodendrocyte precursor cells and ***,recent studies employing single-cell RNA sequencing techniques have uncovered novel cell states,prompting a revision of the existing *** forward,the oligodendroglial lineage should be delineated into five distinct cell states:oligodendrocyte precursor cells,committed oligodendrocyte precursor cells,newly formed oligodendrocytes,myelin-forming oligodendrocytes,and mature *** new classification system enables a deeper understanding of the oligodendroglia in both physiological and pathological *** this uniform terminology will facilitate comparison and integration of data across ***,including the consolidation of findings from various demyelinating models,is essential to better understand the pathogenesis of demyelinating ***,comparing injury models across species with varying regenerative capacities can provide insights that may lead to new therapeutic strategies to overcome remyelination ***,by standardizing terminology and synthesizing data from diverse studies across different animal models,we can enhance our understanding of myelin pathology in central nervous system disorders such as multiple sclerosis,Alzheimer's disease,and amyotrophic lateral sclerosis,all of which involve oligodendroglial and myelin dysfunction.

关键词： animal models demyelination fish mammals multiple sclerosis myelin neurodegeneration oligodendrocytes oligodendroglial lineage remyelination