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Clinical features and treatment outcomes of major depressive disorder with genital symptoms

Chinese Medical Journal 2024年第5期137卷 622-624页

作者： Xiaohui Wu Yuncheng Zhu Ping Sun Shuo Wang Zhiguo Wu Jia Huang Lan cao Yun Wang Yousong Su Zhijian Yao zuowei Wang Fan Wang Yong Wang Daihui Peng Jun Chen Yiru Fang Department of Clinical Research Center&Division of Mood Disorders Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghai 200030China Department of Mood Disorders Shanghai Hongkou Mental Health CenterShanghai 200083China Department of Psychiatry Nanjing Medical University Affiliated Brain HospitalNanjingJiangsu 210029China Department of Psychiatry&Affective Disorders Center Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China CAS Center for Excellence in Brain Science and Intelligence Technology Shanghai 200031China Shanghai Key Laboratory of Psychotic Disorders Shanghai 200118China

To the Editor:Major depressive disorder(MDD)is a mood disorder characterized by complex patterns of emotional,cognitive,and behavioral symptomology and deficits in daily functioning.Genital symptoms,including a reduction in libido and menstrual disturbances,have been considered to be a classic symptom of MDD for many decades.Previous evidence has reached a broad consensus that the incidence of genital symptoms is higher in patients with MDD than in the general population.A systematic review and meta-analysis found a bidirectional association between MDD and genital symptoms,with patients with MDD showing a 50–70%increased risk of developing genital symptoms,while individuals with genital symptoms had a 130–210%increased risk of developing MDD.^([1])As previously reported,50–70%of people with MDD experience sexual dysfunction.^([2])To date,few studies have focused on the comparison of clinical features between patients with MDD with and without genital symptoms,and the longitudinal prognosis.

关键词： symptoms Clinical features

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Co-transplantation of macaque autologous Schwann cells and human embryonic nerve stem cells in treatment of macaque Parkinson's disease

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Asian Pacific Journal of Tropical Medicine 2012年第1期5卷 7-14页

作者： Ying Xia Chengchuan Jiang zuowei cao Keshan Shi Yang Wang Department of Neurosurgery Haikou HospitalXiangya Medical SchoolCentral South University Department of Neurosurgery Huashan HospitalFudan University Department of Neurosurgery Haikou HospitalXiangya Medical SchoolCentral South Unirersity Department of Anatomy Histology and EmbryologyShanghai Medical CenterFudan University

Objective:To investigate the therapeutic effects of co-transplantation with Schwann cells（SCs） and human embryonic nerve stem cells（NSCs） on macaque Parkinson’s disease（PD）.Methods: Macaque autologous SCs and human embryonic NSCs were adopled for the treatment of macaque PD.Results:Six months after transplantation,positron emission computerized tomography showed that 18F-FP-β-CIT was significantly concentrated in the injured striatum in the cotransplanted group.Immunohistoehemieal staining of transplanted area tissue showed migration of tyrosine hydroxylase positive cells from the transplant area to the surrounding area was significantly increased in the co-transplanted group.Conclusions:Co-transplantation of SCs and NSCs could effectively cure PD in macaques.SCs harvested from the autologous peripheral nerves can avoid rejection and the ethics problems,so it is expected to be applied clinically.

关键词： Schwann cells Nerve stem cells Parkinson’s disease Co-transplantation Macaque

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Association of a complete breast cancer pathologic response with axillary lymph node metastasis via neoadjuvant chemotherapy: Results from the CSBrS-012 study

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中华医学杂志(英文版) 2024年第11期137卷 2023 Oct 25页

作者： Ma Le Gao Pin Liu Zhenzhen Jiao Dechuang Ling Rui Xiao Jingjing Zhao Yi Wang Yitong Yang Hongjian Liu Yunjiang Liu Ke Zhang Jianguo Li Guangyan Mao Dahua Deng Yinglei He Jianjun Amina Maimaitiaili Yu Zhigang Fei Wang Liu Yinhua Fu Peifen Yao Minya Wang Jiandong Zhu Li Jiang Hongchuan Zhao zuowei Tian Xingsong cao Zhongwei Ma Xinyu Wu Kejin Fu Shaomei Song Ailin Wang Yanwei Feng Jin Fan Zhimin Department of Breast Surgery Affiliated Wudang Hospital of Guizhou Medical University Guiyang Guizhou China Department of Breast Surgery The First Affiliated Hospital of Xi’an Jiaotong University Xi’an Shaanxi China Department of Breast Surgery The Second Hospital Cheeloo College of Medicine Shandong University Jinan Shandong China Breast Disease Center Peking University First Hospital Beijing China Department of Breast Surgery The First Affiliated Hospital School of Medicine Zhejiang University Hangzhou Zhejiang China Department of General Surgery The First Medical Center Chinese PLA General Hospital Beijing China Department of Breast Surgery Beijing Chaoyang Hospital Capital Medical University Beijing China Department of Breast Surgery The Second Affiliated Hospital of Dalian Medical University Dalian Liaoning China Department of Breast and Thyroid Surgery Shandong Provincial Hospital Affiliated to Shandong University Jinan Shandong China Department of Thyroid Breast Hernia Surgery The Inner Mongolia Autonomous Region People’s Hospital Hohhot Inner Mongolia Autonomous Region China Department of Breast Surgery General Surgery Center The First Hospital of Jilin University Changchun Jilin China Department of Breast Surgery Obstetrics and Gynecology Hospital of Fudan University Shanghai China Department of General Surgery Lanzhou University Second Hospital Lanzhou Gansu China Department of Breast Surgery The First Hospital of China Medical University Shenyang Liaoning China Department of Breast Disease Henan Breast Cancer Center Affiliated Cancer Hospital of Zhengzhou University &amp Henan Cancer Hospital Zhengzhou Henan China Department of Thyroid Breast and Vascular Surgery Xijing Hospital Fourth Military Medical University Xi’an Shaanxi China Surgical Oncology Department Shengjing Hospital of China Medical University Shenyang Liaoning China Department of Breast Surgery The Cancer Hospital of the University of Chinese Academy of Sciences

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Influence of amplified spontaneous emission and fluorescence of β-carotene on stimulated Raman scattering of carbon disulfide

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Science China(Physics,Mechanics & Astronomy) 2009年第4期52卷 529-533页

作者： MEN ZhiWei SUN XiuPing FANG WenHui LI zuowei cao Biao GAO ShuQin LU GuoHui Department of Physics Jilin UniversityChangchun 130021China Department of Physics Changchun University of Science and TechnologyChangchun 130022China

β-carotene with double fluorescence characteristics and large third-order optical nonlinearities,which is dissolved in the carbon disulfide(CS2) as the core medium of a liquid core optical fiber(LCOF),is applied in the study of the CS2 stimulated Raman scattering(SRS). The results of this study show that when the concentrations of solution are more than 3.72×10-7 mol/L,the amplified spontaneous emis-sion(ASE) of β-carotene is the main factor influencing the threshold and intensity of Stokes lines; when the concentrations of solution are lower than 3.72×10-7 mol/L,the ASE disappears and the fluorescence plays the key role:The high-order Stokes lines may be observed at very low input-laser power,and the Stokes thresholds decrease as the solution concentration increases. The result may be widely used in the study of broadband stimulated radiation laser and seeding laser.

关键词： β-carotene ASE fluorescence SRS LCOF

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Evolution of strontium isotopic composition of sea-water from Late Permian to Early Triassic based on study of marine carbonates,Zhongliang Mountain,Chongqing,China

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Science China Earth Sciences 2008年第4期51卷 528-539页

作者： HUANG SiJing Qing HaiRuo HUANG PeiPei HU zuowei WANG QingDong ZOU MingLiang LIU HaoNian State Key Laboratory of Oil/Gas Reservoir Geology and Exploitation Institute of Sedimentary GeologyChengdu University of TechnologyChengdu 610059China Department of Geology University of ReginaRegina S4S 0A2Canada

Collected from a Late Permian to Early Triassic sedimentary section in the Zhongliang Mountain of Chongqing, Southwest China, sixty marine carbonate samples were measured for the 87Sr/86Sr ratios, and corresponding evolution curve was constructed. The concentrations of SiO2, cao, MgO, Mn and Sr are used to evaluate reservation of strontium isotopic composition for original seawater and the credi-bility of the dissolution method for sample preparation. The results show that most of the samples (except seven samples with the Mn/Sr ratios higher than 2) contain the original geochemistry signa-tures of ancient seawater. Compared to the published 87Sr/86Sr ratios from the Late Permian to Early Triassic, our database reported here is the largest and the curve constructed is the most complete. The strontium isotopic curve from Late Permian to Early Triassic is consistent globally and exhibits a gen-eral trend of steady increase during this period. The minimum of 87Sr/86Sr ratios (0.707011) occurs in the Late Permian (30 m in thickness below the Permian-Triassic boundary), and the maximum (0.708281), near the Early-Middle Triassic boundary. The lack of land plants and the rapid continental weathering result in the increase of 87Sr/86Sr ratios during the interval. The Permian-Triassic boundary in Zhongli-ang Mountain Section has been accepted internationally. The 87Sr/86Sr ratios of six samples near the boundary vary from 0.70714 to 0.70715 with an average of 0.70714, which is consistent with the value of 0.70715 (samples are from articulate brachiopod shells) from Korte et al. published in 2006 (within the error range in experiment). Accordingly, the strontium isotope composition in the Permian-Triassic boundary in this paper is of global significance. It can be confirmed that the 87Sr/86Sr ratios of the sea-water in the Permian-Triassic transition are in the range of 0.70714―0.70715.

关键词： Zhongliang Mountain Chongqing Late Permian-Early Triassic paleoseawater strontium isotope composition

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电渣重熔304NG不锈钢脱氧热力学研究

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中南大学学报（自然科学版） 2023年第11期54卷 4273-4282页

作者：李作伟耿鑫姜周华刘福斌东北大学冶金学院辽宁沈阳110819

以抽锭式电渣重熔304NG不锈钢用Ca F_(2)-Al_(2)O_(3)-Ca O-Mg O-Si O_(2)渣系为研究对象,基于分子离子共存理论(IMCT)和Wagner-Chipman模型进行脱氧热力学研究,分析不同脱氧制度对钢中O、Al、Si及渣中FeO质量分数的影响。研究结果表明... 详细信息

以抽锭式电渣重熔304NG不锈钢用Ca F_(2)-Al_(2)O_(3)-Ca O-Mg O-Si O_(2)渣系为研究对象,基于分子离子共存理论(IMCT)和Wagner-Chipman模型进行脱氧热力学研究,分析不同脱氧制度对钢中O、Al、Si及渣中FeO质量分数的影响。研究结果表明,在无脱氧剂条件下,钢中的Al、Si先后被渣中的FeO氧化,平衡时Al的氧化率为61.3%、Si的氧化率为9.7%,而O的增加量为75.1%;当采用Al,CaSi,Al+CaSi脱氧时,渣中FeO质量分数分别能降低至0.12%,0.24%,0.10%;与单独使用Al,CaSi相比,Al+CaSi复合脱氧剂不仅具有良好的氧势控制能力,而且钢中Al、Si相对于电极原始质量分数变化幅度较小;在电渣重熔过程中,钢中O的质量分数由Al-O平衡决定。

关键词：电渣重熔 304NG 渣系脱氧热力学 Al-O平衡

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聚合物微球与本源微生物的协同驱油效果

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油田化学 2019年第3期36卷 422-427页

作者：韩作为曹丽王晓锋苏明中国石油长庆油田分公司第一采油厂

为深入研究聚合物微球与本源微生物驱油技术在低渗裂缝性油藏的协同驱油效果,研究了聚合物微球对岩心的封堵性,微生物与油藏温度、地层水的配伍性,聚合物微球对菌种繁殖能力影响,并进行了微生物驱和"聚合物微球/复合微生物"驱实验。研... 详细信息

为深入研究聚合物微球与本源微生物驱油技术在低渗裂缝性油藏的协同驱油效果,研究了聚合物微球对岩心的封堵性,微生物与油藏温度、地层水的配伍性,聚合物微球对菌种繁殖能力影响,并进行了微生物驱和"聚合物微球/复合微生物"驱实验。研究结果表明:聚合物微球在低渗岩心中具有较好的注入性,随着聚合物微球在低渗岩心中运移的深入,产生逐级封堵效果。优选的微生物在目标区块储层能很好地生产繁殖,聚合物微球具有良好的协同配伍性,聚合物微球的加入不会影响微生物的繁殖。单独实施本源微生物驱油,油水界面张力可降低47%,驱油效率比水驱提高6.91%;"聚合物微球/复合微生物"驱油体系的驱油效率比水驱提高10.05%,满足了安塞油田王窑区块低渗裂缝油藏的矿场调驱需要。

关键词：聚合物微球本源微生物低渗裂缝性油藏王窑区块调驱

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应用于协议无感知转发交换机的流缓存方法

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电子与信息学报 2018年第11期40卷 2772-2778页

作者：曹作伟陈晓倪宏叶晓舟中国科学院声学研究所国家网络新媒体工程技术研究中心北京100190 中国科学院大学北京100049

协议无感知转发支持任意协议的解析和处理,增强了软件定义网络的可编程能力。为提高转发性能,该文提出一种应用于协议无感知转发交换机的流缓存方法,通过识别匹配和动作的依赖关系,得到匹配字段的绝对位置,用以预先解析报文。为确保流... 详细信息

协议无感知转发支持任意协议的解析和处理,增强了软件定义网络的可编程能力。为提高转发性能,该文提出一种应用于协议无感知转发交换机的流缓存方法,通过识别匹配和动作的依赖关系,得到匹配字段的绝对位置,用以预先解析报文。为确保流缓存的加速效果,根据匹配类型与表项数量选择应用流缓存的流表。此外,该文对比了单流表缓存与多流表缓存对转发性能的提升,并提出了根据网络流量实际情况的自适应切换策略。通过扩展POFSwitch实现所提方法,并用实际规则与骨干网流量进行验证,应用流缓存后,交换机报文转发速率提升了220%。流缓存可以为可编程数据平面提供更高的转发性能。

关键词：软件定义网络协议无感知转发可编程数据平面流缓存

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SiO_(2)对抽锭式电渣重熔渣系物性参数的影响

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钢铁 2023年第12期58卷 54-61页

作者：李作伟耿鑫姜周华刘福斌东北大学冶金学院辽宁沈阳110819

抽锭式电渣重熔用渣系具有合适的物性参数,可保证工艺操作的平顺性和电渣钢优良的表面质量。采用半球法和旋转柱体法测定渣系的熔化温度特性和高温黏度,结合XRD、拉曼光谱仪对渣系的析出相与高温结构进行测定与分析,探究了SiO_(2)对抽... 详细信息

抽锭式电渣重熔用渣系具有合适的物性参数,可保证工艺操作的平顺性和电渣钢优良的表面质量。采用半球法和旋转柱体法测定渣系的熔化温度特性和高温黏度,结合XRD、拉曼光谱仪对渣系的析出相与高温结构进行测定与分析,探究了SiO_(2)对抽锭电渣用CaF_(2)-cao-Al_(2)O_(3)-MgO-SiO_(2)渣系的宏观物性参数和微观结构特征的影响规律。研究结果表明,随着w(SiO_(2))增加,渣中低熔点析晶相CaF_(2)减少,高熔点析晶相Ca_(2)Al_(2)SiO_(7)、CaAl_(4)O_(7)增加,熔渣的半球点温度由1 559 K升高至1 589 K,渣系S2、S3的半球温度和流淌温度很接近,说明该渣系在共晶成分附近,高温稳定性较好;温度T不小于1 673 K时,熔渣黏度值随着w(SiO_(2))增加而增加,温度T小于1 673 K时,熔渣黏度值随着w(SiO_(2))增加而降低,且黏度随温度变化的敏感性降低,具有良好的黏度稳定性,适用于抽锭式电渣重熔工艺。熔渣黏流活化能和四面体中非桥氧数量的拟合与计算结果表明,当w(SiO_(2))由1%增加到6%时,渣系的黏流活化能由63.5 kJ/mol增大到91.5 kJ/mol,表明渣系黏度稳定的温度区间变大,有利于重熔时形成薄而均匀的渣壳,且渣中复杂的阴离子团数量增加;拉曼光谱结果证实,渣中的主要构成QSi1、QSi2由无到有、由弱变强,[Si—O]四面体结构显著提高了熔渣网状结构的稳定性,熔渣的聚合程度增加,高温结构复杂化,使高温下熔渣黏度值升高。

关键词： SiO_(2) 电渣重熔渣系熔化温度特性黏度

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东平湖表层沉积物中有机氯农药(OCPs)污染特征研究

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环境科学与管理 2022年第2期47卷 149-154页

作者：何作伟曹建荣朱成达刘衍君泰安市生态环境局肥城分局山东肥城271600 聊城大学地理与环境学院山东聊城252059 赛飞特工程技术集团有限公司山东青岛266000

以东平湖为研究对象,于2015年7月采集了东平湖16个表层沉积物样品,按照规范和质量控制流程,在山东省黄河三角洲生态环境重点实验室,采用Agilent7890GC-μECD气相色谱仪测试其HCH、DDTs和∑OCPs的数据。在此基础上,分析了本研究区有机氯... 详细信息

以东平湖为研究对象,于2015年7月采集了东平湖16个表层沉积物样品,按照规范和质量控制流程,在山东省黄河三角洲生态环境重点实验室,采用Agilent7890GC-μECD气相色谱仪测试其HCH、DDTs和∑OCPs的数据。在此基础上,分析了本研究区有机氯农药的污染特征,并对其生态风险进行了评价。结果表明东平湖表层沉积物的有机氯农药含量范围分别为73.227~140.257 ng/g;HCH、DDTs还是∑OCPs的含量都呈现出从湖区南部向湖区北部逐渐递增的趋势。DDTs、OCPs含量与TOC含量、HCHs含量与TOC含量、pH的相关系数较低,相关性不显著;DDTs、∑OCPs与pH存在显著的正相关关系。对表层沉积物中有机氯农药进行生态风险评价结果显示,相较于HCHs,DDTs对东平湖生物产生的不利影响的可能性极大,总体来看,东平湖表层沉积物中有机氯农药存在一定的生物毒性风险。

关键词：有机氯农药(OCPs) 污染特征表层沉积物生态风险东平湖

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