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芸豆皮多酚制备、纯化、鉴定及抗油脂氧化作用研究

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食品工业科技 2025年第2期46卷 292-300页

作者：孙立兰王坤张友良王若坤左锋黑龙江八一农垦大学食品学院国家杂粮工程技术中心大庆老街基农副产品有限公司粮食副产物加工与利用教育部工程研究中心

为了探究紫花芸豆皮多酚的制备纯化工艺及抗油脂氧化作用，本研究以紫花芸豆皮为原料，采用单因素实验考察了提取溶剂浓度、提取温度、提取时间、料液比和提取次数对芸豆皮多酚提取量的影响；利用HPD600大孔树脂对芸豆皮多酚粗提液进行... 详细信息

为了探究紫花芸豆皮多酚的制备纯化工艺及抗油脂氧化作用，本研究以紫花芸豆皮为原料，采用单因素实验考察了提取溶剂浓度、提取温度、提取时间、料液比和提取次数对芸豆皮多酚提取量的影响；利用HPD600大孔树脂对芸豆皮多酚粗提液进行了纯化，并采用液相色谱质谱联用仪分析酚类物质组成；以过氧化值为指标利用Arrhenius方程建立花生油的货架期预测模型。结果表明，乙醇浓度60%、提取温度70℃、提取时间40 min、液料比1:60(g:mL)、提取次数4次为芸豆皮多酚的最佳提取条件，此时芸豆皮多酚提取量为0.18±0.49 g/g;HPD600大孔树脂对紫花芸豆皮多酚的静态吸附容量、解吸率最大，适合分离纯化紫花芸豆皮多酚，最佳纯化工艺为上样流速1.0 mL/min、洗脱剂乙醇浓度60%和洗脱流速1.0 mL/min，此时芸豆皮多酚纯度为54.68%±1.97%；芸豆皮中含有19种单体酚，其中儿茶素含量最高，为425.952±7.652μg/g；添加芸豆皮多酚或抗氧化剂能有效延缓食用油过氧化值升高，通过模型推算多酚-维生素C复配的花生油在20℃条件下的货架期最长可达193.4 d，对照组货架期为150.3 d，与实测值最大相对误差为8.7%，可准确预测该食用油的货架期。综上，芸豆皮多酚具有较强的抗氧化性，具有安全的天然食品抗氧化剂的潜在用途。

关键词：芸豆皮多酚分离鉴定抗油脂氧化货架期

Helicobacter pylori infection and risk of gastric cancer in Changle County,Fujian Province,China

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World Journal of Gastroenterology 2000年第3期6卷 374-376页

作者： Lin Cai Shun Zhang Yu zuo feng Zhang Department of Epidemiology Fujian Medical UniversityFuzhou 350004Fujian ProvinceChina Department of Epidemiology Shanghai Medical UniversityShanghai 200032China Department of Epidemiology UCLA School of Public HealthLos Angeles CaliforniaUSA

AIM To evaluate the effects of Helicobacterpylori infection and other environmental factorson the development of gastric *** A population-based case-controlstudy was conducted in Changle County,*** primary gastric cancer cases werehistologically confirmed or diagnosed by surgerybetween,January 1996 and March *** were randomly selected and matched byage,sex,and neighborhood of *** of 101 pairs were included in the *** trained interviewers conducted face-to-face interviews with the subjects according toa standardized *** infections were measured by serum IgGantibody to Helicobacter *** Regression analysis was *** The presence of IgG antibody toHelicobacter pylori was 63.7% in studysubjects,56.0% in patients with cardiac cancer,and 60.5% in patients with non-cardiac *** risk factors of gastric cancer inChangle County were identified such as loweducational level[OR=3.864;95% confidenceinterval(95% CI)1.604-9.311],lowconsumption of fresh vegetables(OR=4.925;95%Cl 1.356-17.885),high intake of fish sauce(OR=10.587;95% Cl 2.821-39.738),unscheduled meals(OR=4.254;95%Cl 1.445- 12.552),and Helicobacter pylori infection(OR=3.453;95%Cl 0.901-13.224).CONCLUSION Helicobacter pylori infectionmay be important in the etiology of gastriccancer,but major risk factors other thanHelicobacter pylori are responsible for the highgastric morbidity in Changle County.

关键词： Helicobacter pylori stomach neoplasm risk factors case control studies

Human Factors Analysis in Software Engineering

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Wuhan University Journal of Natural Sciences 2004年第1期9卷 18-22页

作者： XuRen-zuo MaRuo-feng LiuLi-na XiongZhong-wei StateKeyLaboratoryofSoftwareEngineering WuhanUniversityWuhan430072HubeiChina

The general human factors analysis analyzes human functions, effects and influence in a system. But in a narrow sense, it analyzes human influence upon the reliability of a system, it includes traditional human reliability analysis, human error analysis, man-machine interface analysis, human character analysis, and others. A software development project in software engineering is successful or not to be completely determined by human factors. In this paper, we discuss the human factors intensions, declare the importance of human factors analysis for software engineering by listed some instances. At last, we probe preliminarily into the mentality that a practitioner in software engineering should possess. Key words human factors analysis - software engineering - software reliability CLC number TP 311.5 Foundation item: Supported by the National Natural Science Foundation of China (60173013)Biography: Xu Ren-zuo (1946-), male, Professor, research direction: software engineering, software reliability engineering, software safety and software testing.

关键词： human factors analysis software engineering software reliability

Pulmonary diseases induced by ambient ultrafine and engineered nanoparticles in twenty-first century

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National Science Review 2016年第4期3卷 416-429页

作者： Tian Xia Yifang Zhu Lina Mu zuo-feng Zhang Sijin Liu State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of Sciences Division of Nano Medicine Department of MedicineUniversity of California Los Angeles Department of Environmental Health Sciences Fielding School of Public HealthUniversity of California Los Angeles Department of Epidemiology and Environmental Health School of Public Health and Health ProfessionsUniversity at Buffalo Department of Epidemiology Fielding School of Public HealthUniversity of California Los Angeles

Air pollution is a severe threat to public health globally,afecting everyone in developed and developing countries *** diferent air pollutants,particulate mater(PM),particularly combustion-produced ine PM(PM2.5) has been shown to play a major role in inducing various adverse health *** associations have been demonstrated by epidemiological and toxicological studies between increases in PM2.5 concentrations and premature mortality,cardiopulmonary diseases,asthma and allergic sensitization,and lung *** mechanisms of PM-induced toxicological efects are related to their size,chemical composition,lung clearance and retention,cellular oxidative stress responses and pro-inlammatory efects locally and *** in the ultraine range(<100 nm),although they have the highest number counts,surface area and organic chemical content,are oten overlooked due to insuicient monitoring and risk ***,ample studies have demonstrated that ambient ultraine particles have higher toxic potential compared with *** addition,the rapid development of nanotechnology,bringing ever-increasing production of nanomaterials,has raised concerns about the potential human exposure and health *** these add to the complexity of PM-induced health efects that largely remains to be determined,and mechanistic understanding on the toxicological efects of ambient ultraine particles and nanomaterials will be the focus of studies in the near future.

关键词： air pollution particulate mater pulmonary disease ultraine particle nanoparticle

Stable isotopes of water as a tracer for revealing spatial and temporal characteristics of groundwater recharge surrounding Qinghai Lake,China

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Journal of Mountain Science 2022年第9期19卷 2611-2621页

作者： LI Dong-sheng CUI Bu-li ZHAO Yun-duo zuo feng-lin State Key Laboratory of Marine Geology Tongji UniversityShanghai 200092China School of Ocean and Earth Science Tongji UniversityShanghai 200092China School of Resources and Environmental Engineering Ludong UniversityYantai 264025China School of Natural Resources Faculty of Geographical ScienceBeijing Normal UniversityBeijing 100875China Advanced Interdisciplinary Institute of Environment and Ecology Beijing Normal UniversityZhuhai 519087China

Studying spatial and temporal characteristics of regional groundwater recharge will guide the scientific management and sustainable development of regional water *** study investigated stable isotopes(δ^(18)O and δ^(2) H)of precipitation,groundwater,river water and lake water during 2019-2020 in Qinghai Lake Basin to reveal the spatial and temporal characteristics of groundwater *** local meteoric water line was simulated using ordinary least squares regression(δ^(2) H=7.80δ^(18)O+10.60).The local evaporation lines of the river water,lake water and groundwater were simulated asδ^(2) H=6.21δ^(18)O-0.72,δ^(2) H=5.73δ0-3.60 and δ^(2) H=6.59δ0+1.76,*** δ^(2) H and δ^(18)O of river water and groundwater were in more depleted values due to the recharge by precipitation at high altitudes or precipitation effects,and theδ^(2) H andδ^(18)O of the lake water were in more enriched values because of *** relationship between the δ^(2) H and δ^(18)O of groundwater and river water was not significantly different,indicating a strong hydrological connection between the groundwater and river water surrounding Qinghai ***,the maximum values of δ^(18)O and the minimum values of lc-excess of groundwater in most regions were both in August,and the minimum values of δ^(18)O and the maximum values of lc-excess of groundwater in most regions were both in ***,the groundwater was recharged by soil water with strong evaporation in August and recharged by precipitation at high altitudes in *** recharge rate of groundwater was relatively fast in areas with large slopes and large hydraulic gradients(e.g.,south of Qinghai Lake),and in areas with strong hydrological connections between the groundwater and river water(e.g.,the Buha River Valley).Those results can provide data support for protection and utilization of water resources in Qinghai Lake Basin,and provide reference for groundwater research in closed lake basi

关键词： Recharge of groundwater Hydrogen and oxygen stable isotopes Line-conditioned excess Surface water and groundwater Qinghai Lake Basin

Corrosion resistance properties of colored zirconium conversion coating and powder coating on cold-rolled steel

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Rare Metals 2023年第3期42卷 1005-1010页

作者： Ai-Hua Wu Yao-Zu Wang Tong-Kuan Xu Zhi Li Sheng-Ji Luan feng-zuo Qu Shenzhen Key Laboratory of Environment Simulation and Pollution Control PKU-HKUST Shenzhen-HongKong InstitutionShenzhen 518057China Faculty of Light Industry and Chemical Engineering Dalian Polytechnic UniversityDalian 116034China

Jiuhe Corporation developed a new surface pretreatment for producing a phosphate-free and colored zirconium conversion coating on cold-rolled steel(CRS).Scanning electron microscopy(SEM)and energy-dispersive spectroscopy(EDS)were applied to study the surface morphology and elemental composition of the golden yellow-colored conversion *** trochemic al impedance spectroscopy(EIS)was used to investigate the electrochemical performance of the conversion coatings with different *** corrosion resistance properties of the powder coatings were characterized using the neutral salt spray test(NSS)and the tape adhesion *** EIS and NSS results demonstrate that the colored zirconium conversion coatings exhibit excellent corrosion resistance properties compared with the bare *** golden yellow-colored conversion coating has a maximum EIS value(748Ω·cm^(2))and achieves 0 mm degree of corrosion,as stipulated by EN ISO *** paper proposes a hypothesis concerning the ZrO_(2)-(β-FeOOH)-polymer conversion reaction to explain the color changes.

关键词： Surface pretreatment Colored conversion coating Zirconium oxide Powder coating Corrosion protection

Analyzing Influencing Factors of Rural Poverty in Typical Poverty Areas of Hainan Province: A Case Study of Lingao County

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Chinese Geographical Science 2018年第6期28卷 1061-1076页

作者： ZHANG Jinping zuo feng ZHOU Yanmei ZHAI Mengxiao MEI Lin FU Yidi CHENG Yeqing College of Geography and Environmental Sciences Hainan Normal University College of International Education Hainan Normal University

Rural poverty and poverty reduction are not only the focal issues that have attracted worldwide attention, but also the vital issues on people's livelihood that has attached great importance and aimed to be solved by the central and local governments of China. Based on the survey data of 354 farming households, this paper, taking the national poverty county of Lingao County, Hainan Province for an example, examined the characteristics of rural poverty of the county. Moreover, this paper established the spatial lag model(SLM) from five dimensions, namely, status of the household head, household structure, health status, income composition and traffic accessibility, to analyze the main influencing factors of rural poverty according to the values of Moran's I and the diagnosis of spatial dependence of the OLS model. It is found that the poor farming households gathered mainly in five towns in the north and southwest of the county, and the rural poverty have the characteristics of low educational level of the heads, more minor children, high population of farming peasants, high incidence of disease and low proportion of household wage-equivalent income. The results also showed that the variables such as the number of minor children, the number of migrant worker, the number of farming peasants and the proportion of wage-equivalent income have significant effectiveness on rural poverty, while the status of the household head, health status and traffic accessibility have little influence. It is an important way to realize the goal of poverty alleviation by controlling the number of farmers' fertility, strengthening the vocational skills training of farmers, vigorously developing specialization and large-scale agriculture and increasing the employment opportunities of farmers.

关键词： rural poverty targeted poverty alleviation spatial lag model Lingao County China

Misdiagnosis of pancreatic metastasis from renal cell carcinoma:A case report

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World Journal of Clinical Cases 2022年第25期10卷 9012-9019页

作者： Xuan-Kun Liang Lu-Jing Li Ye-Mei He zuo-feng Xu Department of Medical Ultrasonics The Seventh Affiliated Hospital of Sun Yat-sen UniversityShenzhen 518107Guangdong ProvinceChina

BACKGROUND Pancreatic metastases account for only a small proportion of all pancreatic *** pancreatic metastasis from renal cell cancer(isPM-RCC)is extremely rare and may be difficult to differentiate from more common primary neoplasms.A history of nephrectomy is crucial for the *** SUMMARY We report the case of a 64-year-old Asian man who was diagnosed with a mass in the pancreatic head using computed *** had no related symptoms,and his medical history was unremarkable,except for unilateral nephrectomy performed to remove a“benign”tumor 19 years *** preoperative imaging findings suggested a diagnosis of pancreatic neuroendocrine ***,ultrasound-guided biopsy revealed features of clear cell renal cell carcinoma(ccRCC).Re-examination of the specimen resected 19 years ago confirmed that he had a *** pancreatic mass was resected and pathological examination confirmed *** Misdiagnosis of isPM-RCC is common because of its rarity and the long interval from resection of the primary tumor and manifestation of the *** history of the previous surgery may be the only clue.

关键词： Renal cell carcinoma Pancreatic neuroendocrine tumor Pancreatic metastases Case report

Comparative Analysis of Codon Usage Patterns Among Mitochondrion, Chloroplast and Nuclear Genes

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Journal of Integrative Plant Biology 2007年第2期49卷 246-254页

作者： Wen-Juan Zhang Jie Zhou zuo-feng Li Li Wang Xun Gu Yang Zhong Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering School of Life Sciences Fudan University Shanghai 200433 China Department of Genetics and Cell Biology Center for Bioinformatics and Biological Statistics Iowa State University Ames IA 50011 USA Shanghai Center for Bioinformation Technology Shanghai 201203 China

In many organisms, the difference in codon usage patterns among genes reflects variation in local base compositional biases and the intensity of natural selection. In this study, a comparative analysis was performed to investigate the characteristics of codon bias and factors in shaping the codon usage patterns among mitochondrion, chloroplast and nuclear genes in common wheat （Triticum aestivum L.）. GC contents in nuclear genes were higher than that in mitochondrion and chloroplast genes. The neutrality and correspondence analyses indicated that the codon usage in nuclear genes would be a result of relative strong mutational bias, while the codon usage patterns of mitochondrion and chloroplast genes were more conserved in GC content and influenced by translation level. The Parity Rule 2 （PR2） plot analysis showed that pyrimidines were used more frequently than purines at the third codon position in the three genomes. In addition, using a new alterative strategy, 11, 12, and 24 triplets were defined as preferred codons in the mitochondrion, chloroplast and nuclear genes, respectively. These findings suggested that the mitochondrion, chloroplast and nuclear genes shared particularly different features of codon usage and evolutionary constraints.

关键词： chloroplast codon usage mitochondrion neutral mutation nuclear gene selection constraint Triticum aestivum.