检索结果-南通市图书馆

CD4^(+)T淋巴细胞及身体成分与重庆市老年HIV感染者生理衰弱的关联分析

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华预防医学杂志 2024年第2期58卷 235-240页

作者：陈晨徐杰江震吴国辉张裕强赵燕吴尊友中国疾病预防控制中心性病艾滋病预防控制中心北京102206 重庆市疾病预防控制中心重庆400042 重庆市江津区疾病预防控制中心性病艾滋病预防控制科重庆402260 中国疾病预防控制中心性病艾滋病预防控制中心治疗与关怀室北京102206

目的探索CD4^(+)T淋巴细胞(CD4细胞)计数水平与老年HIV感染者生理衰弱患病的关联关系及体成分指标对二者的修饰作用。方法2022年5—10月于重庆市江津区疾病预防控制中心辖区内7家抗病毒治疗点招募485例接受抗反转录病毒治疗(ART)的老年... 详细信息

目的探索CD4^(+)T淋巴细胞(CD4细胞)计数水平与老年HIV感染者生理衰弱患病的关联关系及体成分指标对二者的修饰作用。方法2022年5—10月于重庆市江津区疾病预防控制中心辖区内7家抗病毒治疗点招募485例接受抗反转录病毒治疗(ART)的老年HIV感染者。采用自制问卷通过面对面调查收集对象基本特征(年龄和性别)、生活习惯(吸烟和饮酒情况)和疾病史情况(包括代谢性疾病、心脑血管疾病、呼吸系统疾病和恶性肿瘤)等资料。采用Fried量表评估研究对象的生理衰弱情况。进行体质(步速、握力、身高和体重)和体成分(骨骼肌量、体脂肪量和基础代谢率)测量。由中国艾滋病综合防治数据信息管理系统获取对象抗反转录病毒治疗资料。计算老年感染者生理衰弱现患率,采用多因素logistic回归探索不同CD4水平对老年HIV感染者生理衰弱的影响,并对体成分指标进行亚组分析探索是否存在交互作用。结果485例对象年龄为(72±5)岁,其中>70岁者占48.2%(234例),男性占70.9%(344例),且已全部启动抗病毒治疗。老年HIV感染者生理衰弱率为7.4%(36/485)。多因素logistic回归模型分析显示:调整年龄、性别、吸烟、饮酒、体成分指标、ART时长、病毒载量和合并症数量等因素后,CD4细胞水平增加与老年HIV感染者生理衰弱患病风险下降相关;CD4细胞每增加5.0×10^(7)个/L,老年感染者生理衰弱患病风险下降12%[OR(95%CI):0.88(0.76~1.01)];与CD4细胞低水平组相比,CD4细胞正常水平组生理衰弱风险下降69%[OR(95%CI):0.31(0.10~0.92)]。体成分指标亚组分析显示:CD4细胞水平与生理衰弱的关联在高骨骼肌量和高基础代谢率感染者中更强(P交互值<0.05)。结论重庆市老年HIV感染者生理衰弱率相对较低;CD4细胞水平、骨骼肌量和基础代谢率与生理衰弱有关联。

关键词： HIV 老年人 CD4^(+)T淋巴细胞身体成分生理衰弱

经男男性行为感染HIV者无保护性行为发生因素的定性研究

在线全文

学校读者我要写书评

暂无评论

中国艾滋病性病 2024年第5期30卷 471-474页

作者：熊勇超徐杰罗巍董薇江震王韶嵘周楚吴尊友中国疾病预防控制中心性病艾滋病预防控制中心北京102206 中国红十字会总会训练中心北京100010

目的探究经男男性行为感染HIV者发生无保护性行为的相关因素。方法2023年5-8月在6个城市的疾病预防控制中心、HIV抗病毒治疗门诊和社会组织,招募2020年1月以后新报告的经男男性行为感染HIV者,采用定性研究的方法进行一对一深入访谈。结... 详细信息

目的探究经男男性行为感染HIV者发生无保护性行为的相关因素。方法2023年5-8月在6个城市的疾病预防控制中心、HIV抗病毒治疗门诊和社会组织,招募2020年1月以后新报告的经男男性行为感染HIV者,采用定性研究的方法进行一对一深入访谈。结果共访谈了65名HIV感染者,其中青年学生18人,<50岁社会男性33人,≥50岁社会男性14人。自报因临时性伴感染40人,因固定性伴感染22人,无法确认感染来源3人。关于与临时性伴发生无保护性行为的相关因素,青年学生以HIV预防措施认知不足和存在较强侥幸心理为主,<50岁社会男性除以上因素,还包括物质滥用,≥50岁社会男性以HIV预防措施认知不足为主。与固定性伴发生无保护性行为的相关因素主要是存在盲目的信任心理。结论预防措施认知不足、侥幸心理、物质滥用、群交行为及对固定性伴的信任是MSM无保护性行为发生的相关因素,不同亚组MSM无保护性行为发生因素有所不同,应根据亚组人群的特点采取针对性的HIV干预措施。

关键词：男男性行为者艾滋病病毒无保护性行为定性研究

A Pilot Program of Pre-Exposure and Post-Exposure Prophylaxis Promotion among Men Who Have Sex with Men-7 Study Sites, China, 2018–2019

在线全文

学校读者我要写书评

暂无评论

China CDC weekly 2020年第48期2卷 917-919页

作者： Xiaofang Wang Jie Xu zunyou wu National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina

Summary What is already known on this topic?Pre-exposure prophylaxis(PrEP)and post-exposure prophylaxis(PEP)had been proved to be effective in HIV prevention among men who have sex with men(MSM)*** of either PrEP or P... 详细信息

关键词： prevention China. Sites

Control of HIV/AIDS can be achieved with multi-strategies

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Global Health Journal 2019年第2期3卷 29-32页

作者： Roger Detels Jing wu zunyou wu Department of Epidemiology Fielding School of Public HealthUniversity of California at Los AngelesCA 90095USA Department of Epidemiology School of Public HealthAnhui Medical UniversityHefei 230032China Division of HIV Prevention National Center for AIDS/STD Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China

Over past three decades,many prevention strategies have been proven effective in reducing human immunodeficiency virus (HIV) ***,none of these strategies alone are effective to stop the spread of *** review discusses a few key prevention strategies,including testing,harm reduction,prevention,prophylaxis,and modern communication *** argue that although there are great challenges remaining to stop HIV transmission via sexual contact and injecting drug use routes,the combination of these effective strategies,control HIV epidemic can be achieved.

关键词： HIV Prevention strategy Control Epidemic

Reported Cases of Respiratory Infectious Diseases--China,January−June,2018−2020

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China CDC weekly 2020年第38期2卷 747-748页

作者： Songwang Wang Yewu Zhang zunyou wu Xuemei Su Information Center Chinese Center for Disease Control and Prevention National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention

FIGURE *** number of respiratory infectious diseases(RID)and non-respiratory infectious diseases(non-RID)in China from January to June in 2018–*** infectious diseases included measles,tuberculosis,epidemic cerebrospinal meningitis,pertussis,scarlet fever,seasonal influenza,diphtheria,infectious atypical pneumonia,avian influenza H7N9,and coronavirus disease 2019(COVID-19).Non-respiratory infectious diseases refer to other notifiable infectious diseases except respiratory infectious diseases.

关键词： H7N9 respiratory diseases

Risks and challenges of HIV infection transmitted via blood transfusion

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biosafety and Health 2019年第3期1卷 124-128页

作者： Sarah Robbins Scott zunyou wu National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention155 Changbai RoadBeijing 102206China

Promoting biosafety regulations and techniques supports human health and protects individuals and groups from harmful *** attention should be paid to those potential infectious hazards associated with blood and other bodily fluids,especially those highly transmitted infectious diseases,such as human immunodeficiency virus(HIV),one of the largest global health *** innovative and adaptive screening and laboratory techniques to reduce the possibility of HIV transmission are integral to managing the *** review here the evolution and success of blood screening techniques for HIV,along with current issues that still need to be *** academic articles and media reports about nosocomial HIV transmission events since 1981 were reviewed to identify current blood screening and transfusion safety trends across the globe,along with specific recommendations from the Chinese *** most initial screening was limited only to antibody and antigen testing,newer screening tests(such as nucleic acid testing),coupled with risk-based screening of donors,have led to reduced risk of HIV transmission and continues to reduce the“window period,”when an HIV-positive individual may test negative though they have been *** examination of current guidelines and regulations across the globe are discussed,in order to understand where critical gaps in screening may *** examination of this data,it is evident that huge strides have been made since the beginning of the epidemic;however improved technical training of staff and streamlined testing guidelines could help promote efficient screening of HIV,while also supporting those providing care.

关键词： Human immunodeficiency virus Blood screening Nosocomial transmission Transfusion-transmitted infection

Epidemiology of HIV/AIDS in China: recent trends

在线全文

学校读者我要写书评

暂无评论

Global Health Journal 2017年第1期1卷 26-32页

作者： Yan Cui Cynthia X.Shi zunyou wu National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and PreventionBeijing 102206China National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and PreventionBeijing 102206China Department of Epidemiology of Microbial Diseases and Center for Interdisciplinary Research on AIDS Yale School of Public Health135 College StreetNew HavenCT 06520USA

We used nationally reported cases (NCAIDS/China CDC,2016) and published literature to summarize up-to the end of 2015 epidemiologic trends in the HIV/AIDS epidemic in ***-positive cases are distributed unevenly with most infections found in southwest China and the most affected population being men who have sex with *** mode of HIV infection has shifted from drug injection to sexual contact,which accounts for 95% of total reported *** thirds of cases are from heterosexual *** pattern varies greatly throughout *** provinces in China reported heterosexual transmission accounted for over 90% of cases while other provinces reported homosexual transmission accounted for over 80% of *** of heterosexually acquired HIV also vary widely,with 80% of cases attributed to commercial sex in some provinces,while in other provinces non-commercial extramarital sex accounted for over 70% of *** increase in HIV infection was observed among young students aged *** has successfully controlled blood transfusion-and injecting drug-related transmissions of *** and non-commercial extramarital heterosexual transmissions have become new challenges for China's HIV/AIDS *** adoption of the UNAIDS/WHO 90-90-90 target will help overcome these new challenges.

关键词： HIV AIDS epidemiology China

Asymptomatic and Pre-Symptomatic COVID-19 in China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Infectious Diseases of Poverty 2020年第3期9卷 1-2页

作者： zunyou wu Jennifer M.McGoogan National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention155 Changbai RoadChangping DistrictBeijing 102206China

As the novel coronavirus disease 2019(COVID-19)pandemic spreads rapidly across the globe many unanswered questions about the basic biology and epidemiology of the disease hamper our response strategies and limit our ability to achieve control and prevent a rebound or so-called“second wave”.One such crucial question is:To what degree do asymptomatic cases contribute to transmission?Early,small studies on this subject have found wide ranging estimates of the prevalence of asymptomatic carriers,and just a handful of studies so far have documented viral shedding by asymptomatic cases[1].We recently re-examined China’s COVID-19 case report data to investigate this question[2].This Editorial aims to describe how asymptomatic cases contribute to transmission and what the implications are for control strategies.

关键词： Novel coronavirus disease 2019 Asymptomatic Pre-symptomatic Transmission

在线全文

学校读者我要写书评

暂无评论

中国防治艾滋病30年主要成就与挑战

中华流行病学杂志 2015年第12期36卷 1329-1331页

作者：吴尊友中国疾病预防控制中心性病艾滋病预防控制中心 102206

自1985年首例艾滋病病例报告至今,艾滋病在我国流行已经整整30年.在过去的30年里,中国艾滋病流行在传播方式、受害人群与波及地域等方面发生了巨大变化.同时,中国应对艾滋病流行的防治策略与措施,发生了从被疫情牵着鼻子走到主动出击、... 详细信息

自1985年首例艾滋病病例报告至今,艾滋病在我国流行已经整整30年.在过去的30年里,中国艾滋病流行在传播方式、受害人群与波及地域等方面发生了巨大变化.同时,中国应对艾滋病流行的防治策略与措施,发生了从被疫情牵着鼻子走到主动出击、围剿歼灭的转变.本文回顾30年来,艾滋病在中国的流行变化,防治工作取得的主要进展及面临的挑战.

关键词：艾滋病防治成就挑战