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Splenectomy may facilitate systemic therapy for advanced hepatocellular carcinoma with hypersplenism

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Hepatobiliary Surgery and Nutrition 2023年第1期12卷 137-139页

作者： Er-Lei zhang zun-yi zhang Zhi-Yong Huang Hepatic Surgery Center Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina

Hepatocellular carcinoma(HCC)is the second leading cause of cancer-related deaths globally and is widely considered to be a serious threat to human *** clinical settings,more than 70%of HCCs are unresectable at initial diagnosis and are therefore treated with palliative rather than curative treatment,which severely reduces the overall survival of HCC patients(1).

关键词： diagnosis carcinoma curative

Treatment for hepatocellular carcinoma with tumor thrombosis in the hepatic vein or inferior vena cava:A comprehensive review

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World Journal of Gastrointestinal Surgery 2021年第8期13卷 796-805页

作者： zun-yi zhang Er-Lei zhang Bi-Xiang zhang Xiao-Ping Chen Wei zhang Research Laboratory and Hepatic Surgery Center Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 434000Hubei ProvinceChina

Hepatocellular carcinoma(HCC)is the most common type of liver cancer with a high mortality rate *** percentage of HCC patients with vascular invasion is ***,tumor thrombus in the hepatic vein(HVTT)has a lower incidence than tumor thrombus in the portal vein(PVTT).Conventionally,HCC patients with HVTT are treated the same as HCC patients with PVTT and offered sorafenib or other systemic ***,according to recent studies,it is evident that HCC with HVTT shows different outcomes when classified into different *** this review,we discuss the recent progress and changes in treatment of HCC with HVTT.

关键词： Hepatocellular carcinoma Vascular invasion Surgery Transarterial chemoembolization

Scientific Hepatectomy for Hepatocellular Carcinoma

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Current Medical Science 2023年第5期43卷 897-907页

作者： Jin GU Bin-yong LIANG Er-lei zhang zun-yi zhang Xiao-ping CHEN Zhi-yong HUANG Hepatic Surgery Center Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Hepatobiliary and Pancreatic Surgery the Second Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310009China

With advances in imaging technology and surgical instruments,hepatectomy can be perfectly performed with technical precision for hepatocellular carcinoma(HCC).However,the 5-year tumor recurrence rates remain greater than 70%.Thus,the strategy for hepatectomy needs to be reappraised based on insights of scientific *** evidence has suggested that the main causes of recurrence after hepatectomy for HCC are mainly related to underlying cirrhosis and the vascular spread of tumor cells that basically cannot be eradicated by *** transplantation and systemic therapy could be the solution to prevent postoperative recurrence in this ***,determining the severity of liver cirrhosis for choosing the appropriate surgical modality,such as liver transplantation or hepatectomy,for HCC and integrating newly emerging immune-related adjuvant and/or neoadjuvant therapy into the strategy of hepatectomy for HCC have become new aspects of exploration to optimize the strategy of *** this new area,hepatectomy for HCC has evolved from a pure technical concept emphasizing anatomic resection into a scientific concept embracing technical considerations and scientific advances in underlying liver cirrhosis,vascular invasion,and systemic *** introducing the concept of scientific hepatectomy,the indications,timing,and surgical techniques of hepatectomy will be further scientifically optimized for individual patients,and recurrence rates will be decreased and long-term survival will be further prolonged.

关键词： hepatocellular carcinoma scientific hepatectomy liver cirrhosis vascular invasion immunotherapy

Self-assembly of perovskite nanocrystals:From driving forces to applications

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Journal of Energy Chemistry 2024年第1期88卷 561-578,I0013页

作者： yi Li Fei zhang School of Chemical Engineering and Technology Tianjin UniversityTianjin 300072China Collaborative Innovation Center of Chemical Science and Engineering(Tianjin) Tianjin 300072China

Self-assembly of metal halide perovskite nanocrystals(NCs)into superlattices can exhibit unique collective properties,which have significant application values in the display,detector,and solar cell *** review discusses the driving forces behind the self-assembly process of perovskite NCs,and the commonly used self-assembly methods and different self-assembly structures are ***,we summarize the collective optoelectronic properties and application areas of perovskite superlattice ***,we conclude with an outlook on the potential issues and future challenges in developing perovskite NCs.

关键词： Self-assembly Metal halide perovskite Nanocrystals Driving forces

Msx homeobox gene family and craniofacial development

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Cell Research 2003年第6期13卷 429-442页

作者： SYLVIA ALAPPAT Division of Developmental Biology Department of Cell and Molecular Biology Tulane University New Orleans LA 70118 USA.

Vertebrate Msx genes are unlinked, homeobox-containing genes that bear homology to the Drosophila muscle segment homeobox gene. These genes are expressed at multiple sites of tissue-tissue interactions during vertebrate embryonic development. Inductive interactions mediated by the Msx genes are essential for normal craniofacial, limb and ectodermal organ morphogenesis, and are also essential to survival in mice, as manifested by the pheno typic abnormalities shown in knockout mice and in humans. This review summarizes studies on the expression, regulation, and functional analysis of Msx genes that bear relevance to craniofacial development in humans and mice.

关键词： Msx genes craniofacial tooth cleft palate suture development transcription factor signaling molecule.

Elliptical encirclement control capable of reinforcing performances for UAVs around a dynamic target

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Defence Technology（防务技术） 2024年第2期32卷 104-119页

作者： Fei zhang Xingling Shao yi Xia Wendong zhang National Key Laboratory for Electronic Measurement Technology School of Instrument and ElectronicsNorth University of ChinaTaiyuan030051China

Most researches associated with target encircling control are focused on moving along a circular orbit under an ideal environment free from external ***,elliptical encirclement with a time-varying observation radius,may permit a more flexible and high-efficacy enclosing solution,whilst the non-orthogonal property between axial and tangential speed components,non-ignorable environmental perturbations,and strict assignment requirements empower elliptical encircling control to be more challenging,and the relevant investigations are still *** this line,an appointed-time elliptical encircling control rule capable of reinforcing circumnavigation performances is developed to enable Unmanned Aerial Vehicles(UAVs)to move along a specified elliptical path within a predetermined reaching *** remarkable merits of the designed strategy are that the relative distance controlling error can be guaranteed to evolve within specified regions with a designer-specified convergence ***,wind perturbations can be online counteracted based on an unknown system dynamics estimator(USDE)with only one regulating parameter and high computational *** tool demonstrates that all involved error variables are ultimately limited,and simulations are implemented to confirm the usability of the suggested control algorithm.

关键词： Elliptical encirclement Reinforced performances Wind perturbations UAVs

Influence of the Acoustic Liner in Large Eddy Simulation of Longitudinal Thermoacoustic Instability in a Model Annular Combustor

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Journal of Thermal Science 2024年第2期33卷 710-724页

作者： MENG Sheng zhang Man GAO yi AECC Commercial Aircraft Engine Co. Ltd.Shanghai200241China School of Aeronautics and Astronautics Shanghai Jiao Tong UniversityShanghai200240China

Although extensive efforts have been made to dampen the thermoacoustic instability,successfully controlling the pressure oscillations in modern gas turbines or aeroengines remains *** influence of the acoustic liner on the longitudinal thermoacoustic mode in a model annular combustor is investigated by Large Eddy Simulation(LES) in this *** result of the self-excited longitudinal thermoacoustic instability without the liner agrees well with the frequency and acoustic analysis of the pressure mode based on experimental *** different bias flow velocities of the liner located downstream of the combustor are then *** results reveal that the existence of the liner influences not only the acoustic field but also the flow *** the bias velocity is large,it leads to intense turbulence-induced fluctuations,and the pressure oscillation is modulated *** shows that the weak coupling between flow and pressure oscillations plays a significant role in the onset of the intermittency of a thermoacoustic *** on the dynamic analysis of the thermoacoustic system with the acoustic liner,this intermittency is caused by the influence of the flow field on the flame-acoustic ***,a low-order modeling method based on Van der Pol(VdP) oscillator with additive stochastic forcing is conducted to reproduce the evolving dynamics of the thermoacoustic *** the numerical cases demonstrated in this work are relatively simpler than those in a practical combustion system,the results are helpful for us to understand the effect of the acoustic liner and show the attractive potential to apply this device to suppress thermoacoustic instability.

关键词： thermoacoustic instability acoustic liner Large Eddy Simulation low-order modeling

Accurate Distinction of Weak and Strong AC Grids for Emerging Hierarchical-Infeed LCC-UHVDC Systems

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CSEE Journal of Power and Energy Systems 2024年第2期10卷 772-777页

作者： Hao Xiao Xianzhong Duan yi zhang Department of Electrical and Computer Engineering University of ManitobaWinnipeg R3T 2N2ManitobaCanada State Key Laboratory of Advanced Electromagnetic Engineering and Technology Hubei Electric Power Security and High Efficiency Key LaboratorySchool of Electrical and Electronic EngineeringHuazhong University of Science and TechnologyWuhan 430074HubeiChina RTDS Technologies Inc. Winnipeg R3T 2E1ManitobaCanada

Distinction of weak and strong AC grids for emerging hierarchical-infeed LCC-UHVDC systems is important for planning and operation departments. However, accuracy of earlier distinction methods is limited as they were developed by empirical reasoning without rigorous theoretical analysis. Hence in this letter, hierarchical-infeed interactive effective short-circuit ratio (HIESCR) index is first used for strength evaluation of HIDC systems with complex inter-inverter interactions considered. Boundary HIESCR (BHIESCR) is also introduced in the proposed distinction method of weak and strong AC grids. That is, weak (or strong) AC grids are, respectively, identified when HIESCR is less (or greater) than BHIESCR. Second, it is shown BHIESCR remains almost unchanged as 3.0 versus various system parameters and rated operation variables based on rigorous theoretical analysis. This salient feature makes the proposed method more accurate than earlier methods. Finally, the proposed method is validated by simulations based on the PSCAD/EMTDC program.

关键词： Hierarchical-Infeedinteractive effective short-circuit ratio hierarchical-infeed LCC-UHVDC systems inter-inverter interactions strong AC grids weak AC grids

The stable Auslander-Reiten components of certain monomorphism categories

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Science China Mathematics 2024年第3期67卷 505-526页

作者： Rasool Hafezi yi zhang School of Mathematics and Statistics Nanjing University of Information Science and TechnologyNanjing 210044China

Let Λ be an Artin algebra and let Gprj-Λ denote the class of all the finitely generated Gorenstein projective Λ-modules. In this paper, we study the components of the stable Auslander-Reiten quiver of a certain subcategory of the monomorphism category S(Gprj-Λ) containing boundary vertices. We describe the shape of such components. It is shown that certain components are linked to the orbits of an auto-equivalence on the stable category Gprj. In particular, for the finite components, we show that under certain mild conditions,their cardinalities are divisible by 3. We see that this three-periodicity phenomenon reoccurs several times in the paper.

关键词： monomorphism category almost split sequence Auslander-Reiten quiver Gorenstein projective module