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从肝寒理论探讨偏头痛的中医治疗

现代中医临床 2024年第3期31卷 69-72页

作者：卢恩仕刘祖发何丽云中国中医科学院中医临床基础医学研究所北京100700 中国中医科学院望京医院

偏头痛以一侧或两侧头部交替疼痛为主,易反复发作,属中医“头痛”范畴,病机复杂,以内伤头痛为主。内伤头痛多责之于肝,临床辨证不仅要注重肝阳上亢、肝火上炎等基本病机,还应兼顾肝寒,注重温补肝阳、散寒止痛。肝寒头痛以头部两侧及巅... 详细信息

偏头痛以一侧或两侧头部交替疼痛为主,易反复发作,属中医“头痛”范畴,病机复杂,以内伤头痛为主。内伤头痛多责之于肝,临床辨证不仅要注重肝阳上亢、肝火上炎等基本病机,还应兼顾肝寒,注重温补肝阳、散寒止痛。肝寒头痛以头部两侧及巅顶疼痛为主,常伴胁肋胀满、少腹冷痛、胸闷太息等肝气郁滞的症状,以及呃逆呕吐、腹胀便溏、畏寒肢冷等脾肾阳虚的表现。肝寒头痛的辨证论治包括:(1)肝寒犯胃、浊阴上逆。头痛以巅顶疼痛为主,伴干呕、吐涎沫、畏寒喜暖、手足逆冷等,予吴茱萸汤加减治疗。(2)肝风内动、寒热错杂。以头痛、口干渴、纳呆、自觉气上撞心、便溏等为主,予乌梅丸加减治疗。(3)肝血亏虚、寒凝血瘀。以头痛、手足厥冷、少腹冷痛、脉沉细涩等多见,予当归四逆汤为主治疗。并结合临床病案对基于肝寒理论治疗偏头痛进行介绍。

关键词：偏头痛肝寒论治理论探讨临证经验

A new method based on vitrinite reflectance gradient to determine paleotemperature gradient of a petroleum-bearing basin

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Chinese Science Bulletin 1999年第17期44卷 1593-1596页

作者： Xianming Xiao zufa liu Jiagui Shen Dehan liu Chinese Acad Sci Guangzhou Inst Geochem State Key Lab Organ Geochem Guangzhou 510640 Peoples R China

Based on the Arrhenius equation and Karweil method, a simulation calculation has been made on the thermal maturation of organic matter under a series of assuming paleotem-perature gradients. Results show that there was a positive correlation of vitrinite reflectance gradient with paleotemperature gradient and vitrinite reflectance. According to this, a model

关键词： petroleum-bearing basin paleotemperature gradient vitrinite reflectance gradient vitrinite reflectance.

A new method to reconstruct hydrocarbon-generating histories of source rocks in a petroleum-bearing basin——the method of geological and geochemical sections

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Chinese Science Bulletin 2000年第S1期45卷 35-40页

作者： XIAO Xianming liu zufa liu Dehan SHEN Jiagui FU Jiamo State Key Laborotary of Organic Geochemistry Guangzhou Institute of GeochemistryChinese Academy of SciencesGuangzhou 510640China

Via investigating typical Palaeozoic and Mesozoic petroleum-bearing basins in China by using thermal maturation theories of organic matter to improve the conventional Karweil’s method, a new method to reconstruct hydrocarbon-generating histories of source rocks has been suggested. This method, combining geological background with geochemical information makes the calculated VRo closer to the measured one. Moreover, it enables us to make clear the hydrocarbon generation trend of source rocks during geological history. The method has the merits of simple calculation and objective presentation, especially suitable to basins whose sedimentation and tectonic movements are complicated.

关键词： petroleum-bearing basin hydrocarbon-generating histories organic maturation.

Dating hydrocarbon generation and migration based on bitumen reflectance

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Chinese Science Bulletin 2001年第7期46卷 611-614页

作者： Xianming Xiao Dehan liu Jiamo Fu zufa liu Jiagui Shen Chinese Acad Sci Guanzhou Inst Geochem State Key Lab Organ Geochem Guangzhou 510640 Peoples R China

On the basis of thermal maturation theories of organic matter in sediments and an improved Harweil’s method, a method for dating hydrocarbon generation and migration by means of bitumen reflectance has been suggested. A few representative boreholes in the Tazhong Area of the Tarim Basin was investigated by this method. The results indicate that the three phases of bitumen from the Tazhong Area formed during Middle and Late Ordovician, Late Cretaceous-Early Tertiary, and Late Tertiary, respectively. This implicates that there were three phases of hydrocarbon generation and migration occurring in this area during geological history. This study provided a new idea for the geological application of geochemical data of bitumen.

关键词： bitumen reflectance maturity petroleum generation and migration.

Dating formation of natural gas pools using fluid inclusion data from reservoirs

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Chinese Science Bulletin 2002年第18期47卷 1567-1572页

作者： Xianming Xiao zufa liu Jiaku Mi Dehan liu Jiagui Shen Zhiguang Song Chinese Acad Sci Guangzhou Inst Geochem State Key Lab Organ Geochem Guangzhou 510640 Peoples R China

A method has been suggested which is based on the homogenization temperatures and other data of fluid inclusions from a reservoir rock, with the combination of burial and geothermal history of the hosted rock, to date the gas reservoir formation. On the basis of this, a case study of the Carboniferous-Permian gas pools in the Ordos Basin has been conducted. The results have shown that the reservoir sandstones of the gas pool were filled by gases during 125-150 Ma, earlier in the southern area and later in the northern area, which is consistent with the basin’s geological and geochemical background under which the gas pools formed.

关键词： fluid inclusion Ordos Basin geochronology of gas res-ervoir deep basin gas trap.

Observation of hydrocarbon generation and migration of highly-matured carbonates by means of laser-induced fluorescence microscopy

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Chinese Science Bulletin 2000年第S1期45卷 16-20,113-114页

作者： Dehan liu Xianming Xiao Rongfen Jia Jiagui Shen zufa liu Yunpeng Wang Ansong Geng Chinese Acad Sci Guangzhou Inst Geochem State Key Lab Organ Geochem Guangzhou 510640 Peoples R China

Some important information on hydrocarbon generation, inclusion and migration inhighly-matured carbonates of lower Palaeozoic age from the Ordos Basin and Tarim Basin has been analyzed by a newly-combined laser-induced fluorescence microscope (LFM) designed by our laboratory. The following information has been obtained from the lower Ordovician lamellar carbonates with equivalent vitrinite reflectance (Ro) as high as 1.6%-1.7% and residual TOC of 0.14%-0.35% from the Ordos Basin: wide occurrences of oil and source macerals with strong fluorescence, including *** alginite, lamalginite, telalginite and algae-detrinite; fluorescing asphalt among mineral crystals; some groundmass and spheroid-like reservoir bitumen with high maturation levels in the pores of dolomites. Various kinds of fluorescing organic inclusions and asphalt have been found in the carbonates, calcareous shales and silt-shales with high maturation levels from the Cambrian-Ordovician strata in the Tarim Basin. All this helps us find

关键词： laser-induced fluorescence microscopy highly-matured carbonate hydrocarbon generation and migration organic inclusions.

Reevaluation of the effect of Dianxianning on seizure rate of refractory epilepsy as additive treatment in clinical practice

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Frontiers of Medicine 2011年第2期5卷 229-234页

作者： Liyun He Tiancai Wen Shiyan Yan Runjin Li zufa liu Hui Ren Jinmin liu Fengshan Zhang Jianzhong Wu Jian liu Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China Inner Mongolia People’s Hospital Hohhot 010017China Wangjing Hospital of China Academy of Chinese Medical Sciences Beijing 100102China The First Affiliated Hospital of Kunming Medical College Kunming 650032China Beijing University of Traditional Chinese Medicine Oriental Hospital Beijing 100078China Tongliao Hospital Tongliao 026000China China Association Against Epilepsy Beijing 100044China Kunming Chinese Medicine Factory Co. Ltd.Kunming 650228China

We observed the effect of Dianxianning,which was used as additive treatment to treat 206 epilepsy patients,on the epilepsy seizure *** on a multicenter,prospective,randomized,and controlled clinical trial design,we used the seizure rate of epilepsy as the main *** the treatment group comprising 137 patients,we combined Dianxianning with chemical medicine,which is the basic *** the control group with 69 patients,we added *** results showed that 1)Effect on seizure rate:After a three-month treatment,the seizure rate of the treatment group decreased by 37.84%on average,whereas that of the control group decreased by 13.18%on *** comparing the two groups,there was a significant difference between these groups(P<0.05).2)Effect on seizure frequency:As time passed,the frequency in each group gradually *** a three-month treatment,there was a significant difference between the two groups(P<0.05).3)Comparison between the before and after treatment of each group:There was a very significant difference between the two groups(P<0.0001).The results indicated that,as an additive treatment,Dianxianning has a good effect on controlling the epilepsy seizure rate and frequency *** is more effective than using chemical medicine alone.

关键词： Dianxianning epilepsy seizure evaluation

Stable isotopic composition of riverine dissolved inorganic carbon of the Xijiang River Inner Estuary

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Journal of Geographical Sciences 2008年第3期18卷 363-372页

作者： JIAO Shulin TAO Zhen GAO Quanzhou liu Kun SHE Jianwei DING Jian liu zufa School of Geography and Planning Sun Yat-sen University Guangzhou 510275 China School of Geography and Biology Guizhou Normal University Guiyang 550001 China

For researching the spatio-temporal variation of the stable isotopic composition of the riverine dissolved inorganic carbon（DIC）,we had carried out a survey throughout the hydrologic year during which theδ^13CDIC of the surface water and its physicochemical parameter were examined along the Xijiang River Inner Estuarine waterway from September 2006 to June *** was a striking seasonal variation on the averageδ^13CDIC,as the averageδ^13CDIC in summer（-13.91‰）or autumn（-13.09‰）was much less than those in spring（-11.71‰）or winter（-12.26‰）.The riverineδ13C DIC was controlled by decomposed condition of the riverine organic matter linking the seasonal variation of the physicochemical parameter in the surface water according to the correlation analysis which indicated notable relations betweenδ^13CDIC and water temperature（p=0.000;r=-0.569）or betweenδ^13CDIC and oxide-reduction potential（p=0.000;r=0.646）.The striking positive correlation between δ^13CDIC and the sampling distance happened in the summer rainy season,while striking negative correlation happened in the spring dry season,indicating that river-sea interaction influenced water physicochemical parameters and controlled the riverine DIC property in the survey *** view of the riverineδ^13CDIC decreasing for the decomposition of the terrestrial organic matter in the rainy season in summer and increasing for the briny invaded zone extending in the spring dry season along the waterway from the Makou gauging station to the Modaomen outlet,theδ^13CDIC spatio-temporal variation was closely related to the geographical environment of the Xijiang drainage basin.

关键词： Xijiang River Inner Estuary dissolved inorganic carbon stable isotopic carbon spatio-temporal variation

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珠江三角洲湖库水体嗅味物质分布及其去除

湖泊科学 2019年第1期31卷 113-123页

作者：刘祖发陈记臣卓文珊曾珂梁廖逢刘茹中山大学水资源与环境研究中心广州510275 华南地区水循环与水安全广东省普通高校重点实验室广州510275 中山大学测试中心广州510275

采用固相微萃取-气质联用技术对珠江三角洲9个城市共48个湖库水体中的土臭素(GSM)、2-甲基异茨醇(MIB)和2,3,6-三氯苯甲醚(TCA)等5种嗅味物质进行检测,并探讨污水处理厂和自来水厂处理工艺中嗅味物质的浓度变化规律,同时研究强化混凝沉... 详细信息

采用固相微萃取-气质联用技术对珠江三角洲9个城市共48个湖库水体中的土臭素(GSM)、2-甲基异茨醇(MIB)和2,3,6-三氯苯甲醚(TCA)等5种嗅味物质进行检测,并探讨污水处理厂和自来水厂处理工艺中嗅味物质的浓度变化规律,同时研究强化混凝沉淀工艺对嗅味物质的去除效果.结果表明:珠江三角洲湖库水体中嗅味问题最严重的是广州、佛山、肇庆、东莞、惠州和深圳6个城市,各市湖库的嗅味物质平均浓度为70.93～116.61 ng/L;中山、珠海与江门3个城市的嗅味问题不明显,各市湖库的嗅味物质平均浓度为22.78～58.82 ng/L;珠江三角洲的湖库中浓度最高的嗅味物质是MIB、TCA和GSM,这3种嗅味物质占了嗅味物质总浓度的80.18%～100.00%;污水处理厂和自来水厂中的处理工艺对嗅味物质均有一定的去除效果,嗅味物质的去除主要发生在混凝沉淀阶段;污水处理厂对MIB、TCA和GSM的平均去除率分别为53.55%、57.40%和72.90%;自来水厂对MIB、TCA和GSM的平均去除率分别为64.14%、69.63%和36.86%;强化混凝沉淀实验中,当嗅味物质初始浓度为200 ng/L时,Al2O3投加量为13.75 mg/L可使得混凝沉淀工艺对嗅味物质的去除效果最佳且保证铝盐不超标,嗅味物质浓度增大时Al2O3投加量也需增大;反应体系的p H值处于5～8时,混凝沉淀工艺对嗅味物质的去除效果最佳;混凝搅拌速率越快,嗅味物质的去除率越高且越快达到稳定.

关键词：珠江三角洲湖库强化混凝沉淀嗅味物质固相微萃取-气质联用