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Green carbonization of waste coffee grounds into porous C/Fe hybrids for broadband and high-efficiency microwave absorption

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Journal of Materials Science & Technology 2024年第3期170卷 1-10页

作者： Xin Wen Cui Li Hui Liu Guohua fan Yanan Tang Chuncheng Hao Lili Ma Pingan Song Institute of Advanced Electrical Materials College of Materials Science and EngineeringQingdao University of Science and TechnologyQingdao 266042China Center for Future Materials University of Southern QueenslandSpringfieldQLD 4300Australia School of Agriculture and Environmental Science University of Southern QueenslandSpringfieldQLD 4300Australia

Recently great effort s have been focused on designing high-performance microwave absorbers using sustainable biomass resources,but there remains a lack of green and efficient fabrication ***,inspired by natural porous character of biomass waste,we demonstrated a green one-step route to convert waste coffee grounds into porous C/Fe hybrids,and further explored their potential applications for broadband and high-efficiency microwave *** this design,the WCG-20-750(incorporated 20 wt%Fe(C_(5)H_(7)O_(2))_(3)catalyst and carbonized at 750℃)exhibited porous microstructure with the highest char yield of 55.45 wt%.Furthermore,the as-prepared C/Fe hybrids from WCG-20-750 displayed excellent microwave absorption ***,the minimum reflection loss(RL_(min))reached to-52.86 dB and the widest effective absorption bandwidth(EAB)was 6.40 GHz at the thickness of 3.0 *** work provides an economically viable and environmentally friendly strategy to convert biomass wastes into value-added microwave absorbers,ultimately making contributions to the upcycling of renewable biomass resources and the fostering of sustainable environment.

关键词： Waste recycling Microwave absorption Green carbonization Porous carbon Biomass

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RCEP与亚太地区重叠式自由贸易区整合

东北亚论坛 2024年第2期33卷 114-126,128页

作者：范存祺莫敏中国人民大学国际关系学院北京100872 广西民族大学东盟学院南宁530004

以东盟为轴心、“10+1”自由贸易协定为辐条的“东盟+”的自由贸易区网络是当前亚太地区重叠式自由贸易区的显著特征,然而重叠式自由贸易区安排会造成亚太区域经济合作碎片化和复杂化的困局。RCEP作为亚太地区进阶的巨型自由贸易协定,... 详细信息

以东盟为轴心、“10+1”自由贸易协定为辐条的“东盟+”的自由贸易区网络是当前亚太地区重叠式自由贸易区的显著特征,然而重叠式自由贸易区安排会造成亚太区域经济合作碎片化和复杂化的困局。RCEP作为亚太地区进阶的巨型自由贸易协定,在顶层设计上可以有效覆盖多个多边、双边自由贸易安排,通过制度融合与规则对接、政治互信与文明互鉴、经济重塑与话语权提升等三大路径,可有效降低亚太区域经济合作碎片化和复杂化风险,推动亚太地区重叠式自由贸易区整合和实现更高质量的区域经济一体化。中国应该从近期、中期、远期入手,深度参与RCEP等亚太区域经济合作,形成更深层次的对外开放格局,为亚太地区重叠式自由贸易区建设提供增长动力。

关键词： RCEP 重叠式自由贸易区区域经济合作亚太区域经济一体化中国应对

Trialkylsilyl-thiophene-conjugated acceptor for efficient organic solar cells compatible with spin-coating and blade-coating technologies

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Science China Chemistry 2024年

作者： Tengfei Li Qiang Wu Zefan Yao Hairui Bai Wenyan Su Rui Sun Lingxiao Tang Zhaozhao Bi Xiaojun Li Weiguo Zhu Jie min Qunping fan Wei Ma State Key Laboratory for Mechanical Behavior of Materials Xi'an Jiaotong University College of Chemistry and Molecular Engineering Peking University School of Materials Science and Engineering Xi'an University of Science and Technology Jiangsu Engineering Research Center of Light-Electricity-Heat Energy-Converting Materials and Applications School of Materials Science and Engineering and Changzhou University The Institute for Advanced Studies Wuhan University Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Organic Solids Institute of Chemistry Chinese Academy of Sciences

Sidechain engineering as an efficient and convenient strategy has been widely used to optimize molecular structure of photovoltaic materials for boosting power conversion efficiency(PCE) of organic solar cells(OSCs). Herein, a new Y-series acceptor named Y-ThSi with trialkylsilyl-substituted thiophene as conjugated sidechain is developed. Compared with its parental Y6 with multiple intermolecular interactions, Y-ThSi has a unitary molecular packing due to the additional steric hindrance from twodimensional(2D)-conjugated trialkylsilyl-thiophene. Therefore, Y-ThSi shows an obviously blue-shifted absorption with an onset of ～850 nm but significantly up-shifted lowest unoccupied molecular orbital energy level. For the PM6:Y-ThSi pair, the spin-coating OSCs achieve a decent PCE of 14.56% with an impressively high photovoltage(VOC) of 0.936 V. Inspired by its high VOCand narrow absorption, Y-ThSi is introduced into near-infrared absorbing binary PM6:BTP-eC9 host to construct ternary OSCs. Thanks to the complementary absorption, optimized morphology, and minimized energy loss properties, the PM6:BTP-eC9:Y-ThSi-based OSCs offer a higher PCE of 18.34%. Moreover, our developed strategy can overcome the commonly existed PCE drop when the blade-coating towards large-scale printing is used instead. Therefore, a comparable PCE of 18.34% is achieved, which is one of the best values for the blade-coating OSCs so far.

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Licorice-saponin A3 is a broad-spectrum inhibitor for COVID-19 by targeting viral spike and anti-inflammation

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Journal of Pharmaceutical Analysis 2024年第1期14卷 115-127页

作者： Yang Yi Wenzhe Li Kefang Liu Heng Xue Rong Yu Meng Zhang Yang-Oujie Bao Xinyuan Lai Jingjing fan Yuxi Huang Jing Wang Xiaomeng Shi Junhua Li Hongping Wei Kuanhui Xiang Linjie Li Rong Zhang Xin Zhao Xue Qiao Hang Yang min Ye State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityBeijing100191China Yunnan Baiyao International Medical Research Center Peking UniversityBeijing100191China CAS Key Laboratory of Pathogen Microbiology and Immunology Institute of MicrobiologyChinese Academy of SciencesBeijing100101China CAS Key Laboratory of Special Pathogens and Biosafety Center for Biosafety Mega-ScienceWuhan Institute of VirologyChinese Academy of SciencesWuhan430071China University of Chinese Academy of Sciences Beijing100049China Department of Microbiology and Infectious Disease Center School of Basic Medical SciencesPeking University Health Science CenterPeking UniversityBeijing100191China Hubei Jiangxia Laboratory Wuhan430000China Shenzhen Children's Hospital ShenzhenGuangdong518036China

Currently,human health due to corona virus disease 2019(COVID-19)pandemic has been seriously *** coronavirus severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)spike(S)protein plays a crucial role in virus transmission and several S-based therapeutic approaches have been approved for the treatment of ***,the efficacy is compromised by the SARS-CoV-2 evolvement and *** we report the SARS-CoV-2 S protein receptor-binding domain(RBD)inhibitor licorice-saponin A3(A3)could widely inhibit RBD of SARS-CoV-2 variants,including Beta,Delta,and Omicron BA.1,XBB and ***,A3 could potently inhibit SARS-CoV-2 Omicron virus in Vero E6 cells,with EC50 of 1.016μ*** mechanism was related to binding with Y453 of RBD determined by hydrogen-deuterium exchange mass spectrometry(HDX-MS)analysis combined with quantum mechanics/molecular mechanics(QM/MM)***,phosphoproteomics analysis and multi fluorescent immunohistochemistry(mIHC)respectively indicated that A3 also inhibits host inflammation by directly modulating the JNK and p38 mitogen-activated protein kinase(MAPK)pathways and rebalancing the corresponding immune *** work supports A3 as a promising broad-spectrum small molecule drug candidate for COVID-19.

关键词： COVID-19 Inflammation Licorice-saponin A3 Receptor-binding domain(RBD) SARS-CoV-2

METTL14 downregulation drives S100A4^(+)monocyte-derived macrophages via MyD88/NF-κB pathway to promote MAFLD progression

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Signal Transduction and Targeted Therapy 2024年第5期9卷 2176-2192页

作者： Yue-fan Wang Wen-li Zhang Zhi-xuan Li Yue Liu Jian Tan Hao-zan Yin Zhi-chao Zhang Xian-jie Piao min-hao Ruan Zhi-hui Dai Si-jie Wang Chen-yang Mu Ji-hang Yuan Shu-han Sun Hui Liu Fu Yang The Third Department of Hepatic Surgery Eastern Hepatobiliary Surgery Hospital Affiliated to Naval Medical University200438 ShanghaiChina The Department of Medical Genetics Naval Medical University200433 ShanghaiChina Translational Medicine Research Center Medical Innovation Research Division and Fourth Medical Center of the Chinese PLA General Hospital100048 BeijingChina The Department of Pharmaceutical Analysis School of PharmacyNaval Medical University200433 ShanghaiChina Key Laboratory of Biosafety Defense Ministry of Education200433 ShanghaiChina Shanghai Key Laboratory of Medical Biodefense 200433 ShanghaiChina

Without intervention,a considerable proportion of patients with metabolism‐associated fatty liver disease(MAFLD)will progress from simple steatosis to metabolism‐associated steatohepatitis(MASH),liver fibrosis,and even hepatocellular ***,the molecular mechanisms that control progressive MAFLD have yet to be fully ***,we unraveled that the expression of the N6-methyladenosine(m6A)methyltransferase METTL14 is remarkably downregulated in the livers of both patients and several murine models of MAFLD,whereas hepatocyte-specific depletion of this methyltransferase aggravated lipid accumulation,liver injury,and ***,hepatic Mettl14 overexpression alleviated the above pathophysiological changes in mice fed on a high-fat diet(HFD).Notably,in vivo and in vitro mechanistic studies indicated that METTL14 downregulation decreased the level of GLS2 by affecting the translation efficiency mediated by YTHDF1 in an m6A-depedent manner,which might help to form an oxidative stress microenvironment and accordingly recruit Cx3cr1^(+)Ccr2^(+)monocyte-derived macrophages(Mo-macs).In detail,Cx3cr1^(+)Ccr2^(+)Mo-macs can be categorized into M1-like macrophages and S100A4-positive macrophages and then further activate hepatic stellate cells(HSCs)to promote liver *** experiments revealed that CX3CR1 can activate the transcription of S100A4 via CX3CR1/MyD88/NF-κB signaling pathway in Cx3cr1^(+)Ccr2^(+)*** of METTL14 or GLS2,or interfering with this signal transduction pathway such as inhibiting MyD88 could ameliorate liver injuries and *** together,these findings indicate potential therapies for the treatment of MAFLD progression.

关键词： S100A4 MyD88 metabolism

非马尔科夫环境中Werner态的量子非局域关联检验研究

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物理学报 2024年第16期73卷 7-15页

作者：蒋世民贾欣燕樊代和西南交通大学物理科学与技术学院成都610031

以量子信息领域中常使用的Werner态为研究对象,详细地研究了其在两种非马尔科夫相位阻尼环境,即Random-Telegraph(RT)噪声环境、Ornstein-Uhlenbeck(OU)噪声环境,以及非马尔科夫振幅阻尼(AD)环境中演化后的量子非局域关联检验情况.分别... 详细信息

以量子信息领域中常使用的Werner态为研究对象,详细地研究了其在两种非马尔科夫相位阻尼环境,即Random-Telegraph(RT)噪声环境、Ornstein-Uhlenbeck(OU)噪声环境,以及非马尔科夫振幅阻尼(AD)环境中演化后的量子非局域关联检验情况.分别推导了Werner态在RT,OU以及AD环境中密度矩阵随时间的演化结果.基于Clauser-Horne-Shimony-Holt(CHSH)不等式,对演化后的量子态进行了详细的量子非局域关联检验研究.结果表明,Werner态在RT噪声环境和AD环境中存在信息回流现象,导致其量子非局域关联特性存在周期性振荡变化的现象,即随演化时间的增加,量子态能够从不具备量子非局域关联特性重新回到具有量子非局域关联特性的情况.而在OU噪声环境中,由于不存在信息回流现象,量子非局域关联检验值将随演化时间的增加而降低.同时,本文还详细给出了Werner的保真度、量子态与非马尔科夫环境的耦合强度、OU噪声环境和AD环境的线宽、RT环境噪声的翻转率等参数与成功进行量子非局域关联检验的演化时间之间的关系.

关键词：量子非局域关联 Werner态非马尔科夫环境 CHSH不等式相位阻尼振幅阻尼

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Effectiveness and safety of early lens extraction during par plana vitrectomy for proliferative diabetes retinopathy with mild cataract:a randomized clinical trial

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 528-536页

作者： Wei-Bo Feng Lei Zheng Ying-Qi Li Yong-Hao Li Guo-ming Zhang Xian Wang Bing-Qian Liu Ling Jin Yi-Nuo Huang Yang-fan Yang Zi-Dong Chen Da-Hui Ma Qing-Shan Chen Chao-Jun Qin Bing-min Feng Zhu-min Yang Xing Huang Cheng-Jie Yang Sheng-Hui Liu ming-Xing Wu State Key Laboratory of Ophthalmology Guangdong Provincial Key Laboratory of Ophthalmology and Visual ScienceGuangdong Provincial Clinical Research Center for Ocular DiseasesZhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhou 510275Guangdong ProvinceChina Shenzhen Eye Hospital Affiliated to Jinan University Shenzhen 518040Guangdong ProvinceChina The Affiliated Hospital of Guizhou Medical University Guiyang 550004Guizhou ProvinceChina Guangzhou Aier Eye Hospital Guangzhou 510000Guangdong ProvinceChina

●AIM:To evaluate the effectiveness and safety of early lens extraction during pars plana vitrectomy(PPV)for proliferative diabetic retinopathy(PDR)compared to those of PPV with subsequent cataract surgery.●METHODS:This multicenter randomized controlled trial was conducted in three Chinese hospitals on patients with PDR,aged>45y,with mild *** participants were randomly assigned to the combined(PPV combined with simultaneously cataract surgery,i.e.,phacovitrectomy)or subsequent(PPV with subsequent cataract surgery 6mo later)group and followed up for *** primary outcome was the change in best-corrected visual acuity(BCVA)from baseline to 6mo,and the secondary outcomes included complication rates and medical expenses.●RESULTS:In total,129 patients with PDR were recruited and equally randomized(66 and 63 in the combined and subsequent groups respectively).The change in BCVA in the combined group[mean,36.90 letters;95%confidence interval(CI),30.35–43.45]was significantly better(adjusted difference,16.43;95%CI,8.77–24.08;P<0.001)than in the subsequent group(mean,22.40 letters;95%CI,15.55–29.24)6mo after the PPV,with no significant difference between the two groups at *** overall surgical risk of two sequential surgeries was significantly higher than that of the combined surgery for neovascular glaucoma(17.65%vs 3.77%,P=0.005).No significant differences were found in the photocoagulation spots,surgical time,and economic expenses between two *** the subsequent group,the duration of work incapacity(22.54±9.11d)was significantly longer(P<0.001)than that of the combined group(12.44±6.48d).●CONCLUSION:PDR patients aged over 45y with mild cataract can also benefit from early lens extraction during PPV with gratifying effectiveness,safety and convenience,compared to sequential surgeries.

关键词： lens extraction pars plana vitrectomy proliferative diabetic retinopathy cataract simultaneously operations

Serrated flow behavior of GH536 superalloy under different loading rates at room temperature

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Rare Metals 2024年第5期43卷 2317-2323页

作者： Wen-Xiang Gao Dong Ma Li-Li Zhao fan Ye Ling Shao Su-Jun Wu School of Materials Science and Technology Beihang UniversityBeijing100091China

Serrated flow phenomenon has been widely observed among different metals due to the potential influence on their *** tensile tests of nickel-based superalloy GH536 were carried out at loading rates of 0.06,0.60,3.60,and 36.00 mm·min^(-1)at room temperature,*** tensile stress-strain curves demonstrate repetitive and discontinuous yielding behavior,namely serrated *** is observed that the stress-strain curves were dominated by type B serration,and original annealing twin boundaries(TBs)were distorted to various degrees under comparatively different lower tensile *** contrast,the TBs almost disappear,and the type B serrations become smoother and regular under the higher loading *** phenomenon can be attributed to the interactions between TBs and dislocations during tensile *** effects of the mobile and immobile dislocations illustrate the unsteady amplitude of serrations observed in stress-strain *** electron microscope images of tested pieces reveal the interaction of dislocation and TB,with dislocation tangling around the TBs.

关键词： Nickel-based superalloy Serrations Twin boundaries Deformation mechanism

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基于可变元胞与跟驰理论的元胞自动机模型

哈尔滨工业大学学报 2024年第3期56卷 56-67页

作者：贺敏梁鹏刘玖贤杨凡刘杰长安大学公路学院西安710064 公路大型结构安全教育部工程研究中心(长安大学) 西安710064

为准确模拟桥址随机车流荷载,提出基于可变元胞与跟驰理论的元胞自动机(cellular automata,CA)模型。首先,重新定义元胞构成,提出以车辆为核心的动态可变元胞,并将精确的轴间距和轴重信息融入车辆元胞,实现车辆荷载的精确模拟;然后,引... 详细信息

为准确模拟桥址随机车流荷载,提出基于可变元胞与跟驰理论的元胞自动机(cellular automata,CA)模型。首先,重新定义元胞构成,提出以车辆为核心的动态可变元胞,并将精确的轴间距和轴重信息融入车辆元胞,实现车辆荷载的精确模拟;然后,引入跟驰理论,提出基于跟驰理论的状态演化规则,推导每辆车的专有加速度,实现车辆微观交互的模拟;最后,提出基于实测动态称重系统(weigh in motion,WIM)数据的发车规则,依据WIM数据,重构任意时段的实际车队,并建立基于车头时距的发车规则,重现车辆通过WIM时的运动状态。基于所提出的发车规则和动态演化规则,实现车辆从进入道路到驶离道路全过程时空位置的准确模拟,结合融入精确轴载的车辆元胞,实现随机车流荷载的模拟。基于实测WIM数据验证所提模型的可行性和先进性。结果表明:可变元胞可以精确模拟车辆荷载;提出的状态演化规则可以根据不同车辆的运动状态计算得到每辆车的专属加速度,准确模拟每辆车在自由行驶和跟驰行驶时的不同运动状态;新发车规则可以重构任意时段的实测车队,结合新状态演化规则,可以实现桥址任意时段随机车流的模拟。结合精细化车辆荷载模拟和合理的车流模拟,可实现桥址随机车流荷载模拟。

关键词：桥梁工程随机车流模拟新型元胞自动机轴载跟驰理论转换规则