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Zataria multiflora and its constituent,carvacrol,counteract sepsis-induced aortic and cardiac toxicity in rat:Involvement of nitric oxide and oxidative stress

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Animal Models and Experimental Medicine 2023年第3期6卷 221-229页

作者： Mahmoud Hosseini zohreh arab Farimah Beheshti Akbar Anaeigoudari Farzaneh Shakeri Arezoo Rajabian Psychiatry and Behavioral Sciences Research Center Mashhad University of Medical SciencesMashhadIran Applied Biomedical Research Center Mashhad University of Medical SciencesMashhadIran Neuroscience Research Center Torbat Heydariyeh University of Medical SciencesTorbat HeydariyehIran Department of Physiology School of Paramedical SciencesTorbat Heydariyeh University of Medical SciencesTorbat HeydariyehIran Department of Physiology School of MedicineJiroft University of Medical SciencesJiroftIran Natural Products and Medicinal Plants Research Center North Khorasan University of Medical SciencesBojnurdIran Department of Physiology and Pharmacology School of MedicineNorth Khorasan University of Medical SciencesBojnurdIran Department of Internal Medicine Faculty of MedicineMashhad University of Medical SciencesMashhadIran

Background:Zataria multiflora and carvacrol showed various pharmacological prop-erties including anti-inflammatory and anti-oxidant ***,up to now no studies have explored its potential benefits in ameliorating sepsis-induced aortic and cardiac ***,this study aimed to investigate the effects of *** and carvacrol on nitric oxide(NO)and oxidative stress indicators in lipopolysaccharide(LPS)-induced aortic and cardiac ***:Adult male Wistar rats were assigned to:Control,lipopolysaccharide(LPS)(1 mg/kg,intraperitoneal(i.p.)),and *** hydro-ethanolic extract(ZME,50–200 mg/kg,oral)-and carvacrol(25–100 mg/kg,oral)-treated *** was in-jected daily for 14 *** with ZME and carvacrol started 3 days before LPS administration and treatment continued during LPS *** the end of the study,the levels of malondialdehyde(MDA),NO,thiols,and antioxidant enzymes were ***:Our findings showed a significant reduction in the levels of superoxide dis-mutase(SOD),catalase(CAT),and thiols in the LPS group,which were restored by ZME and ***,ZME and carvacrol decreased MDA and NO in car-diac and aortic tissues of LPS-injected ***:The results suggest protective effects of ZME and carvacrol on LPS-induced cardiovascular injury via improved redox hemostasis and attenuated NO ***,additional studies are needed to elucidate the effects of ZME and its constituents on inflammatory responses mediated by LPS.

关键词： carvacrol lipopolysaccharide nitric oxide oxidative injury sepsis Z.multiflora

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Late infection after peri-orbital autologous micro-fat graft:a case presentation and literature review

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 603-606页

作者： Farzad Pakdel Hassan Asadigandomani Melika arab Bafrani zohreh Nozarian Zohre Abedinifar Niloofar Pirmarzdashti Behzad Jafari Zaynab Siami Department of Oculofacial Plastic Surgery Farabi HospitalSchool of MedicineTehran University of Medical SciencesTehran ***Iran Craniomaxillofacial Research Center Tehran University of Medical SciencesTehran ***Iran Department of Ophthalmology School of MedicineTehran University of Medical SciencesTehran ***Iran Department of Pathology Farabi HospitalSchool of MedicineTehran University of Medical SciencesTehran ***Iran Department of Microbiology Farabi HospitalSchool of MedicineTehran University of Medical SciencesTehran ***Iran Pediatric Cell and Gene Therapy Research Center Children’s Medical CenterSchool of MedicineTehran University of Medical SciencesTehran ***Iran

Citation:Pakdel F,Asadigandomani H,arab Bafrani M,Nozarian Z,Abedinifar Z,Pirmarzdashti N,Jafari B,Siami *** infection after peri-orbital autologous micro-fat graft:a case presentation and literature *** J Ophthalmol ... 详细信息

关键词： graft orbital after

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Hippo-YAP/TAZ signaling in breast cancer:Reciprocal regulation of microRNAs and implications in precision medicine

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Genes & Diseases 2024年第2期11卷 760-771页

作者： Farzad Sadri Seyede fatemeh Hosseini zohreh Rezaei Mohammad Fereidouni Student Research Committee Birjand University of Medical SciencesBirjand ***Iran Tabas School of Nursing Birjand University of Medical SciencesBirjand ***Iran Department of Biology University of Sistan and BaluchestanZahedan ***Iran Cellular and Molecular Research Center Birjand University of Medical SciencesBirjand ***Iran

Breast cancer is a molecularly heterogeneous disease and the most common female *** recent years,therapy approaches have evolved to accommodate molecular diversity,with a focus on more biologically based therapies to minimize negative *** regulate cell fate in human breast cells,the Hippo signaling pathway has been associated with the alpha subtype of estrogen *** pathway regulates tissue size,regeneration,and healing,as well as the survival of tissue-specific stem cells,proliferation,and apoptosis in a variety of organs,allowing for cell *** signaling is mediated by the kinases MST1,MST2,LATS1,and LATS2,as well as the adaptor proteins SAV1 and *** kinases phosphorylate the downstream effectors of the Hippo pathway,yes-associated protein(YAP),and transcriptional coactivator with PDZ-binding motif(TAZ),suppressing the expression of their downstream target *** Hippo signaling pathway kinase cascade plays a significant role in all *** the principles of this kinase cascade would prevent the occurrence of breast *** recent years,small noncoding RNAs,or microRNAs,have been implicated in the development of several malignancies,including breast *** interconnections between miRNAs and Hippo signaling pathway core proteins in the breast,on the other hand,remain poorly *** this review,we focused on highlighting the Hippo signaling system,its key parts,its importance in breast cancer,and its regulation by miRNAs and other related pathways.

关键词： Breast cancer Hippo signaling Large tumor suppressor kinase 1 microRNAs PDZ-binding motif Yes-associated protein

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Physiology of medicinal and aromatic plants under drought stress

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The Crop Journal 2024年第2期12卷 330-339页

作者： zohreh Emami Bistgani Allen V.Barker Masoud Hashemi Isfahan Agricultural and Natural Resources Research and Education Center Agricultural Research Education and Extension Organization(AREEO)Isfahan 81748-35117Iran Stockbridge School of Agriculture University of MassachusettsAmherstMA 01002USA

Drought poses a significant challenge,restricting the productivity of medicinal and aromatic *** strain induced by drought can impede vital processes like respiration and photosynthesis,affecting various aspects of plants’growth and *** response to this adversity,medicinal plants employ mechanisms such as morphological and structural adjustments,modulation of drought-resistant genes,and augmented synthesis of secondary metabolites and osmotic regulatory substances to alleviate the *** water scarcity can lead to leaf wilting and may ultimately result in plant *** cultivation and management of medicinal plants under stress conditions often differ from those of other *** is because the main goal with medicinal plants is not only to increase the yield of the above-ground parts but also to enhance the production of active ingredients such as essential *** elucidate these mechanisms of drought resistance in medicinal and aromatic plants,the current review provides a summary of recent literature encompassing studies on the morphology,physiology,and biochemistry of medicinal and aromatic plants under drought conditions.

关键词： Drought stress Medicinal and aromatic plants Phytochemistry Physiology

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Assessment of groundwater potential using multi-criteria decision analysis and geoelectrical surveying

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Geo-Spatial Information Science 2022年第4期25卷 600-618页

作者： Marzieh Shabani zohreh Masoumi Abolfazl Rezaei Department of Earth Sciences Institute for Advanced Studies in Basic Sciences(IASBS)ZanjanIran Center for Research in Climate Change and Global Warming(CRCC) Institute for Advanced Studies in Basic Sciences(IASBS)ZanjanIran

A precise map of the dispersion of the groundwater potential across each watershed can help decision-makers to exert optimal water management in each *** this research,the potential of groundwater resources in both the Zanjanrood Catchment and the Tarom Region,located in the northwest of Iran,has been *** effective criteria including slope,land-use,drainage density,spring density,lithology,lineament density,and rainfall are *** were first weighted using the Analytical Hierarchical Process(AHP)method and then overlaid by the Technique for Order Preferences by Similarity to Ideal(TOPSIS)***,the spatial zoning map of groundwater potential was obtained in four categories.A sensitivity analysis was performed to determine the influence of each criterion on the obtained *** model was verified using both the spatial distribution of the high-discharged production wells and the geophysical-based geoelectric field *** results indicate that the high-discharged wells(>40 l/s)in both regions are dispersed predominantly in the very good zone and,in several cases,in the good ***,the results from the two-dimensional models of resistivity and induced polarization of geoelectrical field survey are inappropriate agreement with those from the TOPSIS ***,there is no suitable potential zone of groundwater in the surrounding highlands to be used in the future for drinking purposes since the highlands water supply is a strategic supply for *** strategies employed in this study,the results of GIS modeling,and the geoelectrical analysis can be considered for sustainable development of similar arid and semi-arid areas since groundwater is considered as the main supplier of water in such regions.

关键词： Spatial Information System(GIS) Remote Sensing(RS) groundwater potential TOPSIS geoelectrical field survey sustainable development

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Effects of Annealing on the Fabrication of Al-TiAl3 Nanocomposites Before and After Accumulative Roll Bonding and Evaluation of Strengthening Mechanisms

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Acta Metallurgica Sinica(English Letters) 2022年第4期35卷 636-650页

作者： zohreh Yazdani Mohammad Reza Toroghinejad Hossein Edris Department of Materials Engineering Isfahan University of Technology84156-83111 IsfahanIran

The strengthening mechanisms of Al-TiAl_(3) nanocomposite, fabricated using cold roll bonding, annealing, and accumulative roll bonding(ARB) on Al sheets sandwiching with pure Ti powder were investigated in the present study. With annealing at 590 ℃ for 2 h, TiAl_(3) intermetallic compound was formed. After subsequent ARB process up to 5 cycles, final composite consists of ultrafine Al grains of less than 500 nm with TiAl_(3) particles larger than 200 nm. The strength and hardness of the final composite are 2.5 and 3.5 times the initial values, with an ultimate tensile strength of 400 MPa, which is dominated by grain-boundary strengthening due to the ultrafine Al grains, and Orowan strengthening due to the small TiAl_(3) particles. For comparison, an alternative fabrication route of cold roll bonding–ARB–annealing was also studied. This study showed that annealing before ARB is a critical factor in producing an ultrafine grain structure containing TiAl_(3) particles.

关键词： Composite Annealing Strength Microstructure Al

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Effect of copper nanoparticles on thermal behavior of two-phase argon-copper nanofluid flow in rough nanochannels with focusing on the interface properties and heat transfer using molecular dynamics simulation

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Chinese Journal of Chemical Engineering 2022年第2期35卷 344-350页

作者： Shabnam Ghahremanian Abbas Abbassi zohreh Mansoori Davood Toghraie Department of Mechanical Engineering Amirkabir University of TechnologyTehranIran Department of Mechanical Engineering Amirkabir University of TechnologyHafez Ave.P.O.Box 15916-34311TehranIran Energy Research Center Amirkabir University of TechnologyHafez Ave.P.O.Box 15916-34311TehranIran Department of Mechanical Engineering Khomeinishahr BranchIslamic Azad UniversityKhomeinishahrIran

A comparison between the efficacy of surface boundary structure and presence of nanoparticles on the condensation two-phase flow inside rough nanochannels has been accomplished by applying molecular dynamics procedure to evaluate the thermal conductivity and flow *** is performed in a computational region with two copper walls containing rectangular rough elements under different saturated *** main properties of liquid–vapor interface including density and the number of liquid atoms,are *** is observed that the density profile is more affected by nanoparticles than the ***,compared to the condensation of nanofluid in a smooth nanochannel,the rough wall causes a greater drop in the temperature at the early time steps and by development of liquid films,effects of the wall roughness *** the first of the condensation process,adding nanoparticle causes that transferring argon particles to the liquid phase increases with a steeper ***,heat current autocorrelation function(HCACF)for nanofluid condensation flow over considered correlation time is analyzed and following that the thermal conductivity for different saturated conditions is *** has been represented that at lower temperatures the roughness makes more significant influence on the heat transfer of two-phase flow,while at higher temperatures the importance of nanoparticles prevails.

关键词： Two-phase flow Nanofluid Roughness element Thermal conductivity

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Physiology of medicinal and aromatic plants under drought stress

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The Crop Journal 2024年第2期 330页

作者： zohreh Emami Bistgani Allen V.Barker Masoud Hashemi

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Understanding DC Partial Discharge:Recent Progress,Challenges,and Outlooks

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CSEE Journal of Power and Energy Systems 2022年第3期8卷 894-909页

作者： Chuanyang Li Tohid Shahsavarian Mohamadreza arab Baferani Kerry Davis Yang Cao Di Zhang Electrical and Computer Engineering University of Connecticut371 Fairfield WayStorrsCT 06269USA Naval Postgraduate School MontereyCA 93943USA

As a non-destructive local gas breakdown phenomenon within a surface or bulk cavity surrounded by insulation,partial discharge(PD)contains important information which can be used to evaluate and diagnose electrical insulation *** this paper,distinctive characteristics of PD for DC versus AC are reviewed.A summary of experimental studies on DC PD in different insulation coordinations is presented,including PD in gaseous insulating media,PD in solid insulating media and PD in liquid insulating *** and some thoughts based on existing studies are provided,and challenges and suggestions for future studies are *** paper can serve as a guide reference for readers to learn the background and state-of-the-art of DC PD *** importantly,it is hopeful that this study can inspire novel ideas for further advancing fundamental research of DC PD mechanisms and PD mitigation methods.

关键词： Charge injection DC power systems partial discharges surface charging

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A comparison of three surface roughness characterization techniques:photogrammetry,pin profiler,and smartphone-based LiDAR

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International Journal of Digital Earth 2022年第1期15卷 2422-2439页

作者： zohreh Alijani Julien Meloche Alexander McLaren John Lindsay Alexandre Roy Aaron Berg Department of Geography Environment and GeomaticsUniversity of GuelphGuelphCanada Département de Géomatique Appliquée Université de SherbrookeSherbrookeCanada Département des Sciences de l’Environment Université du Québec à Trois-RivièresTrois-RivièresCanada

Surface roughness plays an important role in microwave remote *** the agricultural domain,surface roughness is crucial for soil moisture retrieval methods that use electromagnetic surface scattering or microwave radiative transfer ***,improved characterization of Soil Surface Roughness(SSR)is of considerable *** this study,three approaches,including a standard pin profiler,a LiDAR point cloud generated from an iPhone 12 Pro,and a Structure from Motion(SfM)photogrammetric point cloud,were applied over 24 surface profiles with different roughness variations to measure surface *** objective of this study was to evaluate the capability of smartphone-based LiDAR technology to measure surface roughness parameters and compare the results of this technique with the more common *** showed that the iPhone LiDAR technology,when point cloud data is captured in a fine-resolution mode,has a significant correlation with SfM photogrammetry(R2=0.70)and a relatively close agreement with pin profiler(R2=0.60).However,this accuracy tends to be greater for random surfaces and rough profiles with row structure *** results of this study confirm that smartphone-based LiDAR can be used as a cost-effective,fast,and time-efficient alternative tool for measuring surface roughness,especially for rough,wide,and inaccessible areas.

关键词： LiDAR surface roughness structure from motion iPhone pin profiler

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