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Innovations in endoscopic ultrasound for portal hypertension and its role in managing complications in clinical practice:Lessons learned from a tertiary referral public hospital

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Portal hypertension & Cirrhosis 2024年第1期3卷 31-35页

作者： Cosmas R.A.Lesmana Kemal F.Kalista Saut h.h.Nababan Juferdy Kurniawan Chyntia O.M.Jasirwan Andri S.sulaiman Irsan hasan Rino A.Gani Department of Internal Medicine Hepatobiliary DivisionDr.Cipto Mangunkusumo National General HospitalMedical Faculty Universitas IndonesiaJakartaIndonesia Digestive Disease&GI Oncology Center Medistra HospitalJakartaIndonesia Gastrointestinal Cancer Center MRCCC Siloam Semanggi HospitalJakartaIndonesia

Portal hypertension(Ph)poses significant *** paper presents an innovative study on the utilization of endoscopic ultrasound(EUS)for both the diagnosis and management of *** at *** Mangunkusumo National General hospital in Jakarta,this retrospective case series included patients diagnosed with Ph through clinical examination,imaging evaluation,and *** criteria comprised a history of reduced blood consumption within the last 5 days,hepatocellular carcinoma,massive ascites,or elevated international normalized ratio(>1.4).EUS-guided portal pressure gradient(PPG)measurements were performed using an innovative standard *** study involved 15 patients,with 14 having liver cirrhosis and 1 diagnosed with Budd–Chiari *** them,nine patients experienced bleeding due to gastroesophageal *** and large esophageal varices were identified in four and eight patients,*** varices type 1 were observed in two patients,and type 2 in four *** gastric fundal varices type 1 were present in one *** on EUS-PPG measurements,14 patients exhibited clinically significant portal *** patients underwent endoscopic band ligation and three underwent EUS-guided cyanoacrylate injection during the same session as the EUS-PPG measurement ***,no adverse events,such as abdominal pain,perforation,or bleeding were observed during or after the *** emerges as a promising and accurate tool for both diagnosis and management.

关键词： cyanoacrylate injection endoscopic ultrasound liver cirrhosis portal hypertension portal pressure gradient

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Correlation between the skull base fracture and the incidence of intracranial hemorrhage in patients w让h traumatic brain injury

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Chinese Journal of Traumatology 2019年第5期22卷 286-289页

作者： Ahmad Faried Danny halim Ingrid Ayke Widjaya Rendy Febrian Badri Syailendra Fii sulaiman Muhammad Z.Arifin Department of Neurosurgery Faculty of MedicineUniversitas PadjadjaranDr.Hasan Sadikin HospitalBandungIndonesia Bandung Injury Research Unit Faculty of MedicineUniversitas PadjadjaranBandungIndonesia

Purpose:A head injury(hI)may cause a skull fracture,which may or may not be associated with injury to the *** essence,a skull base fracture(SBF)is a linear fracture at the base of the *** of consciousness and Glasgow coma score(GCS)may vary depending on an associated intracranial *** pathomechanism is believed to be caused by high energy impact directly to the mastoid and supraorbital bone or indirectly from the cranial *** of this study is to define the correlation between SBF and intracranial hemorrhage(ICh)in patients with ***:Analysis of data obtained from a retrospective review of medical records and from a systematized database pertaining to diagnostic criteria of SBF patients based only on clinical symptoms associated with ICh caused by hI treated in the Department of Neurosurgery at *** Sadikin hospital,Bandung,Indonesia from January 1,2012 to December 31,*** exclusion criteria in eluded age less than 15 years and no head computed tomography(CT)scan examination ***:A total of 9006 patients were in eluded into this study in which they were divided into 3 groups:group 1,hI with no ICh;group 2,hI with single ICh and group 3,hI with multiple *** all the SBF cases,SBF at anterior fossa accounted for 69.40%of them,which were mostly accompanied with mild hI(64.70%).Severity of hI and site of SBF correlated with the existence of traumatic brain lesions on CT scan,thus these factors were able to predict whether there were traumatic brain lesions or *** of the patients with epidural hemorrhage(EDh)has single traumatic lesion on CT scan,whereas most of the patients with cerebral contusion(CC)has multiple traumatic lesions on CT *** patients with both traumatic brain injury and SBF,most of the patients with anterior fossa SBF has EDh;whereas most of the patients with middle fossa SBF were accompanied with *** was not required for most of the patients with ***:SBFs were strongly corre

关键词： Skull base fracture Intracranial hemorrhage Traumatic brain injury

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Production of Trimethylolpropane Ester Based Lubricant from Palm Oil

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材料科学与工程（中英文版） 2010年第11期4卷 13-18页

作者： Siti Zubaidah.sulaiman Robiah Yunus Luqman Chuah Abdullah Fakhru＇l-Razi Ahmadun Zulkafli hassan Rohaida Che Man Faculty of Engineering Chemical and Natural Resources Universiti Malaysia Pahang Kuantan 25000 Pahang Malaysia Department of Chemical and Environmental Engineering Faculty of Engineering Universiti Putra Malaysia Serdang 43400 UPM Selangor Malaysia

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Impact of endoscopic ultrasound examination for deep esophageal collateral veins evaluation in liver cirrhosis patients prior to endoscopic treatment:A case series

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Portal hypertension & Cirrhosis 2022年第1期1卷 76-81页

作者： Cosmas Rinaldi A.Lesmana Saut h.Nababan Kemal F.Kalista Juferdy Kurniawan Chyntia O.M.Jasirwan Andri S.sulaiman Irsan hasan Rino A.Gani Department of Internal Medicine Hepatobiliary DivisionDr.Cipto Mangunkusumo National General HospitalJakartaIndonesia Digestive Disease and GI Oncology Center Medistra HospitalJakartaIndonesia

Aim:The presence of esophageal collateral veins(ECV)has been reported to be associated with the recurrence of esophageal varices(EV)and bleeding in liver cirrhotic(LC)*** study aimed to see the potential clinical value of deep collateral veins assessment using endoscopic ultrasound(EUS)in liver cirrhotic patients with ***:During 6 months period,a prospective study is conducted,where we identified LC patients who were admitted for esophagogastroduodenoscopy(EGD)screening at the Department of Internal Medicine,*** Mangunkusumo National General hospital,*** was examined using *** were excluded if they had(1)liver malignancy,(2)history of ligation or glue injection,or(3)portal or splenic vein *** collected demographic data,medical history,data pertaining to use of nonselective beta blocker(NSBB),and laboratory,imaging,and endoscopy *** was performed using a gastroscope(EG29‐i10,3.2 mm Pentax Medical)while EUS was performed using a linear array echoendoscope(EG‐3870UTK,3.8 mm,Pentax Medical)before band ligation or glue ***:There were 20 LC patients included in this study,where 15(75%)of patients were classified with Child-Pugh(CP)‐A and five(25%)of patients with CP‐*** most common aetiologies were hepatitis B in seven(35%)patients and hepatitis C in nine(45%)*** EV with peri‐or para‐esophageal veins(PEEV or PAEV)were detected in 65%of *** of the LC patients with no EV showed the presence of *** or PAEV were detected in grades 1-3 ***:EUS examination can give a better evaluation before managing gastroesophageal varices through deep ECV detection in LC patients.

关键词： endoscopic ultrasound esophageal collateral vein gastroesophageal varices liver cirrhosis portal hypertension

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Assessment of <i>Stevia rebaudiana</i>Bertoni Genotypes via Morpho-Agronomic Traits under Two Light Conditions

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American Journal of Plant Sciences 2018年第7期9卷 1403-1413页

作者： Dhulfiqar Aamer Abdulameer Mohamad Bin Osman Zulkefly sulaiman Mohd Rafi Yusop Shamsiah Abdullah Parisa Azizi Qusay Abdulhamza Muttaleb Department of Crop Science Faculty of Agriculture Universiti Putra Malaysia Serdang Malaysia Institute of Plantation Studies Universiti Putra Malaysia Serdang Malaysia Laboratory of Food Crops Institute of Tropical Agriculture Universiti Putra Malaysia Serdang Malaysia Faculty of Plantation and Agrotechnology Universiti Teknologi MARA Shah Alam Malaysia Technical Institute of Babel Al-Furat Al-Awsat Technical University Al Hillah Iraq

Stevia rebaudiana Bertoni, a non caloric natural sweetner is currently the available substitute to sugar. It is a genus of about 150 species of herbs and shrubs, a compositae and native to Paraguay. however, stevia is a short day plant with almost a constant day length 12 hours in Malaysia stevia generated to flower early. Therefore, the aim of the study was to investigate the effect of different day length on Stevia rebaudiana genotypes in Malaysia. The experiment was undertaken during December 2016 to April 2017 in the Faculty of Design and Architecture, Universiti Putra Malaysia, Serdang, Selangor, Malaysia. Eight stevia genotypes namely (ChV1, Morita2, MS012, MS012 (4x), SA18, TPU, and hybrids IIUM-F1 and UiTM-h2) were evaluated for the agronomic traits under two conditions: sun light (hours) and simulated light (>14 hours) using a factorial experiment. The agronomic performance of Stevia rebaudiana was significantly in long day length (>14 hours) environment comparing with short day length (hours) environment. Stevia plants under sun light start to flower after seven weeks, from the other hand stevia plants under simulated light did not flower. All stevia genotypes showed a high performance under long day length (>14 hours) environments.

关键词： Stevia rebaudiana Propagation Sun Light Simulated Light

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溶剂法制备降血糖肽固体分散体及其稳定性

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精细化工 2022年第5期39卷 956-962页

作者：陈百科李慧金素莱曼包海蓉上海海洋大学食品学院上海201306 上海水产品加工及贮藏工程技术研究中心上海201306 农业部水产品贮藏保鲜质量安全风险评估实验室(上海) 上海201306

以降血糖肽为模型,尤特奇L-100(EL-100)为载体,羟丙基甲基纤维素(hPMC)为释放调节剂,采用溶剂法制备了降血糖肽固体分散体,并对其稳定性和体外释放进行了研究。以降血糖肽固体分散体2h的累积释放率和二肽基肽酶-Ⅳ(DPP-Ⅳ)抑制率为评价... 详细信息

以降血糖肽为模型,尤特奇L-100(EL-100)为载体,羟丙基甲基纤维素(hPMC)为释放调节剂,采用溶剂法制备了降血糖肽固体分散体,并对其稳定性和体外释放进行了研究。以降血糖肽固体分散体2h的累积释放率和二肽基肽酶-Ⅳ(DPP-Ⅳ)抑制率为评价指标,对肠溶载体和释放调节剂配比进行了优化,利用SEM、FTIR和TEM对降血糖肽固体分散体进行了表征,并考察了降血糖肽固体分散体不同储存时间和储存温度下的稳定性。结果表明,在m(降血糖肽)∶m(EL-100)∶m(hPMC)=1∶2∶0.2条件下制备的降血糖肽固体分散体2h的累积释放率达到93.54%,且DPP-Ⅳ抑制率具有较高水平。SEM和TEM分析表明,降血糖肽分散在固体分散体中;FTIR表明,降血糖肽二级结构的构象发生了变化。降血糖肽固体分散体能显著增强降血糖肽的稳定性,常温(25℃)储存10 d后累积释放率仍高达90.32%,在高温环境下也表现出较强的稳定性。

关键词：降血糖肽固体分散技术累积释放率稳定性 DPP-Ⅳ抑制率医药原料

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Emirati Limestones: Impact of Low Temperature Microstructure on the Industrial Applications

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矿物学报 2013年第S1期33卷 87-87页

作者： sulaiman Alaabed Abdel Monem M.Soltan Osman Abdel-Ghani Bahaa Eddin Mahmoud Mohamed ElTokhi Abbas Khalil Abdullah Musalim Geology Department Faculty of ScienceUnited Arab Emirates UniversityAlAin-17551Abu DhabiUae Geology Department Faculty of ScienceAin Shams UniversityCairo-11566Egypt Chemistry Department Faculty of ScienceUnited Arab Emirates UniversityAlAin-17551Abu DhabiUae

The main aim of this work is to study the possibility of using different Emirati limestones for the production of quicklime. Representative limestone samples have been collected to represent the Triassic, Jurassic, Cretaceous, Eocene and Oligocene ages. The limestone samples have been characterized for their microstructure, mineral and chemical composition, physico-mechanical characteristics, thermal behavior using polarizing and scanning microscopes together with X-ray micro-tomography, XRD-IR, XRF, Archimedes and Mercury intrusion methods and DTA-TGA, respectively. Post characterization, the samples were fired in electrical muffle furnace for calcination under the firing conditions (800℃ to 1100℃) for (0.25 – 2 h). Then the lime grains have been characterized for their hydration rate, free lime content, pore-distribution and microfabric.

关键词： limestones calcination industry Emirates

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水动力尾静脉注射介导Akt/β-catenin/Yap质粒转染建立小鼠肝癌模型

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临床与实验病理学杂志 2020年第10期36卷 1185-1190页

作者：蒋雨薇宋海燕李怡萍汤凯悦徐娇雅 sulaiman Andrew MCGARRY Sarah WANG Lisheng 郑培永上海中医药大学附属龙华医院脾胃病研究所上海200032 中加联合脾胃病研究中心上海200032 Department of Biochemistry Microbiology and ImmunologyUniversity of OttawaOttawaON K1H8M5Canada

目的通过应用水动力尾静脉注射(hydrodynamic tail vein injection,hTVi)Sleeping Beauty(SB)质粒及促癌基因质粒,构建一种新型小鼠肝癌模型。方法6周龄雄性C57BL/6J小鼠,按照体重随机分为对照组和模型组。将冻存的SB、Akt、β-catenin... 详细信息

目的通过应用水动力尾静脉注射(hydrodynamic tail vein injection,hTVi)Sleeping Beauty(SB)质粒及促癌基因质粒,构建一种新型小鼠肝癌模型。方法6周龄雄性C57BL/6J小鼠,按照体重随机分为对照组和模型组。将冻存的SB、Akt、β-catenin、Yap质粒转化入感受态*** Dh5α大肠杆菌,于LB培养基扩增后提取质粒。每只模型组小鼠尾静脉快速注射上述质粒混合溶液2 mL,包含SB质粒5μg,Akt、β-catenin、Yap质粒分别15μg,对照组小鼠给予等量PBS尾静脉注射。继续饲养8周后处死小鼠,观察小鼠情况,记录体重、肝重。观察小鼠肝脏病理学变化,并应用Western blot法检测小鼠肝组织中Akt、β-catenin、Yap基因表达水平。结果高压注射质粒8周后,对照组小鼠活动度好,皮毛光亮;小鼠肝脏形态正常;肝组织hE染色显示,对照组小鼠肝小叶结构完整。模型组小鼠活动减少,皮毛无光泽。与对照组比较,模型组小鼠体重下降、肝重增加、肝体比显著上调;模型组小鼠肝脏体积增大,质地较硬,表面出现颗粒状、结节样改变;肝组织hE染色显示,模型组小鼠肝组织结构紊乱,并出现多个肿瘤结节。此外,与对照组相比,模型组小鼠肝组织中Akt、β-catenin、Yap基因表达均明显上调。结论应用水动力尾静脉注射SB质粒及Akt/β-catenin/Yap质粒的方法可成功建立小鼠肝癌模型,为肝癌发病机制及药物研发提供快速、经济的动物模型。

关键词：肝肿瘤动物模型水动力尾静脉注射 SB质粒癌基因

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生姜蛋白酶对干腌羊火腿品质特性的影响

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食品科学 2019年第8期40卷 15-21页

作者：阿尔祖古丽.阿卜杜外力玉素甫.苏来曼巴吐尔.阿不力克木新疆农业大学食品科学与药学学院新疆乌鲁木齐830052

在干腌羊火腿中添加生姜蛋白酶,通过风干成熟促进肌纤维蛋白降解,研究生姜蛋白酶对羊火腿品质特性的影响。以带骨鲜羊后腿肉为实验材料,分别设计4组实验,1组为对照组,另3组为实验组;对照组不采取处理,而实验组按羊腿肉质量以1 000 g为单... 详细信息

在干腌羊火腿中添加生姜蛋白酶,通过风干成熟促进肌纤维蛋白降解,研究生姜蛋白酶对羊火腿品质特性的影响。以带骨鲜羊后腿肉为实验材料,分别设计4组实验,1组为对照组,另3组为实验组;对照组不采取处理,而实验组按羊腿肉质量以1 000 g为单位,分别添加0.01%、0.03%、0.05%的生姜蛋白酶,并在相应条件下进行风干成熟,检测羊火腿风干过程中肌肉剪切力、ph值、水分含量、系水力、硫代巴比妥酸(thiobarbituric acid,TBA)值、总氮含量(totalnitrogen,TN)、非蛋白氮(non-proteinnitrogen,NPN)含量以及蛋白质降解指数(proteolysis index,PI)等品质特性指标。结果表明,与对照组相比,添加0.05%生姜蛋白酶处理组风干成熟(30 d)后肌肉剪切力下降28.17%,TN增加了32%,NPN增加了68%,PI增加了29%(在风干后期(23 d)增加了31%),TBA值在允许的范围内增加了11%;0.05%酶处理组风干后期(23 d)水分质量分数为44.71%,已达到对照组成熟期(30 d)的水分质量分数(46.96%),p h值呈逐渐上升趋势,系水力呈逐渐下降趋势;生姜蛋白酶最佳添加量为0.05%时,可显著促进羊火腿蛋白质和脂肪降解提高嫩度,并促进其水分流失,从而将其成熟周期缩短到23 d。

关键词：生姜蛋白酶添加量干腌羊火腿品质特性

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阜康阿魏的核型分析研究

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中国中药杂志 2006年第2期31卷 114-116页

作者：赵鑫马小军凯撒.苏来蔓付长亮陈瑞阳中国协和医科大学中国医学科学院药用植物研究所北京100094 新疆中药民族药研究所新疆乌鲁木齐830002 南开大学天津300071

目的:对阜康阿魏染色体的核型进行分析研究。方法:根尖用0.000 2 mol.L-18-羟基喹啉处理3 h,卡诺固定液固定3 h,1 mol.L-1盐酸水解5 min,卡宝品红染色2 min,然后制片。结果:阜康阿魏染色体是二倍体,染色体数目为20,染色体核型公式为2n=1... 详细信息

目的:对阜康阿魏染色体的核型进行分析研究。方法:根尖用0.000 2 mol.L-18-羟基喹啉处理3 h,卡诺固定液固定3 h,1 mol.L-1盐酸水解5 min,卡宝品红染色2 min,然后制片。结果:阜康阿魏染色体是二倍体,染色体数目为20,染色体核型公式为2n=16m+4sm。第4,10号染色体为近中着丝粒染色体,其余8对为中部着丝粒染色体。结论:核型类型为2A型,这是一种原始类型。

关键词：阜康阿魏染色体核型分析

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