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Genomic consequences of apple improvement

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Horticulture Research 2021年第1期8卷 97-109页

作者： zoe migicovsky Kyle M.Gardner Christopher Richards C.Thomas Chao Heidi R.Schwaninger Gennaro Fazio Gan-Yuan Zhong Sean Myles Department of Plant Foodand Environmental SciencesFaculty of AgricultureDalhousie UniversityTruroNSCanada USDA-ARS Plant Germplasm Preservation Research UnitFort CollinsCOUSA USDA-ARS Grape Genetics Research UnitGen evaNYUSA Present address:Agriculture and Agri-Food Canada Fredericton Research and Development CentreFrederictonNBCanada

The apple(Malus domestica)is one of the world's most commercially important perennial crops and its improvement has been the focus of human effort for thousands of ***,we genetically characterise over 1000 apple accessions from the United States Department of Agriculture(USDA)germplasm collection using over 30,000 singlenucleotide polymorphisms(SNPs).We con fi rm the close genetic relationship between modern apple cultivars and their primary progenitor species,Malus sieversii from Central Asia,and fi nd that cider apples derive more of their ancestry from the European crabapple,Malus sylvestris,than do dessert *** determine that most of the USDA collection is a large complex pedigree:over half of the collection is interconnected by a series of fi rst-degree *** addition,15%of the accessions have a fi rst-degree relationship with one of the top 8 cultivars produced in the *** the exception of‘Honeycrisp',the top 8 cultivars are interconnected to each other via pedigree *** cultivars‘Golden Delicious'and‘Red Delicious'were found to have over 60 fi rst-degree relatives,consistent with their repeated use by apple *** detected a signature of intense selection for red skin and provide evidence that breeders also selected for increased fi *** results suggest that Americans are eating apples largely from a single family tree and that the apple's future improvement will bene fi t from increased exploitation of its tremendous natural genetic diversity.

关键词： cultivar crops consequences

Upper extremity vascular injuries:Etiology,management and outcome

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World Journal of Critical Care Medicine 2024年第2期13卷 159-167页

作者： Nikolaos Stefanou Theodoros Mylonas Fragkiskos A Angelis Christina Arnaoutoglou Sokratis E Varitimidis zoe H Dailiana Department of Orthopaedic Surgery Faculty of MedicineSchool of Health SciencesUniversity of ThessalyUniversity Hospital of LarissaLarissa 41500Greece Department of Hand Upper Extremity and MicrosurgeryIASO ThessaliasLarissa 41500Greece

BACKGROUND Vascular injuries of the upper extremities are considered relatively rare injuries affecting mostly the young *** often are complex injuries accompanied by other musculoskeletal trauma or trauma in other anatomic *** management is challenging since they can lead to disabilities with major socioeconomic *** To analyze data about the mechanism of injury,the management algorithm and functional outcomes of vascular injuries of the upper *** One hundred and fifteen patients(96 males and 19 females)with arterial injuries of the upper extremity treated in a tertiary trauma center from January 2003 to December 2022 was *** patients’age was 33.7 years and the mean follow up time was 7.4 *** with Mangled Extremity Severity Score≥7 and Injury Severity Score≥20,previous upper limb surgery or major trauma and any neuromuscular or psychiatric disease were excluded,from the *** A penetrating trauma was the most common cause of *** radial artery was the artery injured in most of the cases(37.4%)followed by the ulnar(29.5%),the brachial(12.1%)and the axillary(6%).A simultaneous injury of both of the forearm’s arteries was in 15.6%of the *** 93%of the cases there were other concomitant musculoskeletal injuries of the *** lacerations were the most common,followed by nerve *** postoperative functional scores(full Disabilities of the Arm,Shoulder,and Hand and VAS)had very satisfactory *** Although vascular injuries of the upper extremity are rare,they may occur in the context of major combined musculoskeletal *** a multidisciplinary approach is essential to optimize outcome,the ability of trained hand surgeons to repair all injuries in combined vascular and musculoskeletal upper extremity trauma,excluding isolated vascular injuries,ensures shorter operative times and better functional outcomes.

关键词： Upper extremity Vascular injuries Complex injuries Musculoskeletal trauma Mangled extremity

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千年前的神秘部落国唯有莎车最具西域模样

环球人文地理 2024年第7期 54-63页

作者：陈霄燕郭弋zoe 余小雨徐以默旅行的Joey 王家骏玄清柯基的相机陈小羊

两千年前的西域三十六国，散布在今中国新疆与中亚部分地区。“三十六国”中，大多古名已随风而去，莎车依然沿用古名。走进今日的莎车，仍能感受到扑面而来的西域风情。到过莎车的人，都会感叹它纯正、浓郁的西域风情。这座具有3000多...

两千年前的西域三十六国，散布在今中国新疆与中亚部分地区。“三十六国”中，大多古名已随风而去，莎车依然沿用古名。走进今日的莎车，仍能感受到扑面而来的西域风情。到过莎车的人，都会感叹它纯正、浓郁的西域风情。这座具有3000多年历史的小城，从来不是无名之辈。它是汉代西域三十六国之一莎车国的延续，是明朝赫赫有名的叶尔羌汗国的都城，更是维吾尔族文化空前繁荣的见证。

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Associations between Bodyweight and Clinical Outcome in Patients Post-Fontan Procedure: A Systematic Review

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Congenital Heart Disease 2022年第6期17卷 617-639页

作者： Emma Payne Thomas Wilson Marjan Haghighi zoe McCallum Yves d’Udekem Julian Ayer The University of Sydney SydneyAustralia The University of Melbourne MelbourneAustralia The Royal Children’s Hospital MelbourneAustralia The Royal Prince Alfred Hospital SydneyAustralia The Children’s National Hospital WashingtonUSA

Background: Patients born with a single ventricle circulation commonly experience growth failure in early life,which is associated with adverse outcomes in infancy. However, associations between bodyweight or weight trajectoryand clinical outcome post-Fontan procedure are yet to be determined. Methods: On the 1st of July 2021, asystematic review was performed in MEDLINE, EMBASE, the Cochrane Library, and Scopus of studies of patientswith clinical outcome data post-Fontan procedure and association with bodyweight. Quality of studies was evaluatedby Newcastle–Ottawa scale for cohort studies and Joanna Briggs Institute tool for cross-sectional ***: Of 527 studies that underwent title and abstract screening, 15 were selected for final review. An increasedrisk of adverse post-Fontan outcomes was found for low weight patients, consistent with findings in *** there is some evidence to suggest increased mortality in overweight adult patients, studies are conflictingas to whether overweight status is associated with increased heart failure. Increased BMI is associated with diminishedexercise capacity and deceased physiological functioning. Negative weight trajectory is associated withadverse outcomes in the peri-Fontan period, whereas a positive weight trajectory is associated with increased Fontanfailure in adulthood. Abnormal BMI (high or low) is associated with increased heart failure and poorer performancein quality-of-life scores. Conclusions: Bodyweight is a modifiable risk factor for poor clinical outcomein patients with a single ventricle circulation. Recognizing associations between bodyweight and Fontan pathophysiologymay help to define patient-centered exercise and diet interventions that minimize patient morbidityand mortality.

关键词： Fontan bodyweight congenital heart disease single ventricle

FedTC:A Personalized Federated LearningMethod with Two Classifiers

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Computers, Materials & Continua 2023年第9期76卷 3013-3027页

作者： Yang Liu Jiabo Wang Qinbo Liu Mehdi Gheisari Wanyin Xu zoe L.Jiang Jiajia Zhang School of Computer Science and Technology Harbin Institute of TechnologyShenzhen518055China Guangdong Provincial Key Laboratory of Novel Security Intelligence Technologies Shenzhen518055China Research Center for Cyberspace Security Peng Cheng LaboratoryShenzhen518055China

Centralized training of deep learning models poses privacy risks that hinder their *** learning(FL)has emerged as a solution to address these risks,allowing multiple clients to train deep learning models collaborativelywithout sharing ***,FL is vulnerable to the impact of heterogeneous distributed data,which weakens convergence stability and suboptimal performance of the trained model on local *** is due to the discarding of the old local model at each round of training,which results in the loss of personalized information in the model critical for maintaining model accuracy and ensuring *** this paper,we propose FedTC,a personalized federated learning method with two classifiers that can retain personalized information in the local model and improve the model’s performance on local *** divides the model into two parts,namely,the extractor and the classifier,where the classifier is the last layer of the model,and the extractor consists of other *** classifier in the local model is always retained to ensure that the personalized information is not *** receiving the global model,the local extractor is overwritten by the globalmodel’s extractor,and the classifier of the globalmodel serves as anadditional classifier of the localmodel toguide local *** FedTCintroduces a two-classifier training strategy to coordinate the two classifiers for local model *** results on Cifar10 and Cifar100 datasets demonstrate that FedTC performs better on heterogeneous data than current studies,such as FedAvg,FedPer,and local training,achieving a maximum improvement of 27.95%in model classification test accuracy compared to FedAvg.

关键词： Distributed machine learning federated learning data hetero-geneity non-independent identically distributed

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Check

小学生时代（大嘴英语） 2023年第3期 20-21页

作者： zoe 不详

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Big,Big,Big

小学生时代（大嘴英语） 2023年第7期 34-36页

作者： zoe 不详

small的反义词big,也是我们的老朋友了。无论是体积、程度,还是数量,只要和“大”沾边,就是big!哥哥和弟弟都是brother,姐姐和妹妹都是sister,该怎么区分?前面提到small是“年幼的”,big就是“年长的”。哥哥叫big brother,姐姐就叫big ... 详细信息

small的反义词big,也是我们的老朋友了。无论是体积、程度,还是数量,只要和“大”沾边,就是big!哥哥和弟弟都是brother,姐姐和妹妹都是sister,该怎么区分?前面提到small是“年幼的”,big就是“年长的”。哥哥叫big brother,姐姐就叫big sister。

关键词： sister brother 反义词

Let's Talk about Books

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小学生时代（大嘴英语） 2023年第4期 24-27页

作者： zoe 不详

如果故事里的人物能“跳”出来思考,会不会也爱上自己所属的那本书?在这个读书月,不妨来场大胆的设想,让主角们讲讲书的事儿。P.S.你能猜到他们分别来自哪个故事吗?Are you reading...?What'sitabout?Who is your favourite author?What... 详细信息

如果故事里的人物能“跳”出来思考,会不会也爱上自己所属的那本书?在这个读书月,不妨来场大胆的设想,让主角们讲讲书的事儿。P.S.你能猜到他们分别来自哪个故事吗?Are you reading...?What'sitabout?Who is your favourite author?What type of books do you enjoy?How'sthe book?Youmust be well-read.

关键词： What enjoy Books

Genetics of congenital anomalies of the hand

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World Journal of Orthopedics 2022年第11期13卷 949-954页

作者： Zisis Kyriazis Panagoula Kollia Ioanna Grivea Sotirios Sotiriou zoe H Dailiana Department of Orthopaedic Surgery Faculty of MedicineSchool of Health SciencesUniversity of ThessalyLarissa 41500Greece Department of Genetics and Biotechnology Faculty of BiologyNational and Kapodistrian University of AthensAthens 10679Greece Department of Paediatrics Faculty of MedicineSchool of Health SciencesUniversity of ThessalyLarissa 41500Greece Laboratory of Histology and Embryology Faculty of MedicineSchool of Health SciencesUniversity of ThessalyLarissa 41500Greece

Congenital anomalies of the hand are malformations occurring during the development of the human limb,and present as isolated disorders or as a part of a *** the last years,molecular analysis techniques have offered increasing knowledge about the molecular basis of hand *** in the signaling pathways during the development of the upper limb result in malformations of the upper *** present,several genes have been identified as responsible for hand anomalies and other have been recognized as suspect genes related to *** and new high throughput methods have been introduced for the identification of the gene *** the current editorial,we summarize concisely the current molecular status of isolated hand genetic disorders and the recent progress in molecular genetics,including the genes related to the *** progress improves the knowledge of these disorders and has implications on genetic counselling and prenatal diagnosis.

关键词： Hand Gene Mutation Molecular Diagnosis Disorders