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The COVID-19 pandemic:some thoughts on integrity in research and communication

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Forensic Sciences Research 2021年第3期6卷 310-315页

作者： David Morens zoëhammatt National Institute of Allergy and Infectious Diseases National Institutes of HealthBethesdaMarylandUSA University of Hawaii and Z Consulting HonoluluHawaiiUSA

Principles of integrity and ethical practice in research have been reinforced and honed over *** medical and biomedical fields,they have been shaped by challenges that include endemic,emerg-ing,and re-emerging diseases[1],as well as the scientific responses to each disease as it *** responses include clinical and community prevention trials,vaccine and drug trials for persons with life-threatening diseases,applied and basic research with dangerous microbial agents,and many *** fatal pandemics caused by novel agents-for which neither drugs nor vaccines exist-present additional urgent challenges for scientists,defined here to mean biomedical,medical,and pub-lic health scientists and *** addition to conducting research,scientists are also often tasked with communicating research findings,not only to those who make policy decisions,but also to the media and the public.

关键词： prevention shaped policy

Spotlight on research integrity:international insights on strengthening research culture in the forensic sciences and beyond

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Forensic Sciences Research 2021年第3期6卷 281-282页

作者： zoëhammatt University of Hawaii and Z Consulting HonoluluHawaiiUSA

The Singapore Statement on Research Integrity,artic-ulated during the 2nd World Conference on Research Integrity in 2010,encompasses principles that apply to all research endeavours,including the various disci-plines that comprise the field of forensic science.(Singapore Statement on Research Integrity(2010)(https://***/guidance/singapore-statement)).Cases of research misconduct and breaches of research integ-rity in any field undermine the trustworthiness of research and make it difficult if not impossible for others to rely upon and replicate research ***,problems in the research environment,whether in the academic,public,or private sector,can include bullying and harassment,discrimination,abuse of power and corruption,as well as competitive pres-sures related to employment and status.

关键词： strengthening culture statement

Small extrachromosomal circular DNA in amyotrophic lateral sclerosis matter

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Neural Regeneration Research 2025年第5期20卷 1411-1413页

作者： Marcos J.Arauzo-Bravo Daniela Gerovska Matthias Schwab Alexandra Kretz Computational Biology and Systems Biomedicine Biodonostia Health Research InstituteSan SebastianSpain Basque Foundation for Science IKERBASQUEBilbaoSpainMax Planck Institute for Molecular BiomedicineComputational Biology and Bioinformatics GroupMünsterNorth Rhine-WestphaliaGermany Department of Cell Biology and Histology Faculty of Medicine and NursingUniversity of Basque Country(UPV/EHU)LeioaSpain Department of Neurology Jena University HospitalJenaThuringiaGermany

Comprehensive studies identify motor neuron spectrum disorders including amyotrophic lateral sclerosis(ALS)as globally rising fatal disorders with the highest prevalence in aging populations,influenced by ethnicity and ancestry(GBD 2016 Motor Neuron Disease Colla borators,2018).While~10% of diagnoses involve a family history(fALS),most cases are considered sporadic(sALS).However,population-based studies suggest that even cases without a common index mutation impart heritability(Ryan et al.,2019),indicating a crucial role of rare and as yet unknown genetic denominators.

关键词： amyotrophic sclerosis

Inequalities for the Extended Best Polynomial Approximation Operator in Orlicz Spaces

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Acta Mathematica Sinica,English Series 2019年第2期35卷 185-203页

作者： Sonia ACINAS Sergio FAVIER Felipe zo Departamento de Matemática Facultad de Ciencias y Exactas NaturalesUniversidad Nacional de La Pampa Instituto de Matemática Aplicada San Luis IMASLUniversidad Nacional de San Luis and CONICET Departamento de Matemática Universidad Nacional de San Luis

In this paper we pursue the study of the best approximation operator extended from L~Φ to L~φ, where φ denotes the derivative of the function Φ. We get pointwise convergence for the coefficients of the extended best approximation polynomials for a wide class of function f, closely related to the Calder′on–Zygmund class t_m^p(x) which had been introduced in 1961. We also obtain weak and strong type inequalities for a maximal operator related to the extended best polynomial approximation and a norm convergence result for the coefficients is derived. In most of these results, we have to consider Matuszewska–Orlicz indices for the function φ.

关键词： Orlicz spaces extended best polynomial approximation pointwise and norm convergence weak and strong type inequalities Orlicz indices

Preparation of Porous Silica Ceramics with Low Dielectric Constant

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Chinese Journal of Aeronautics 2006年第B12期19卷 239-243页

作者： MAO Xiao-jian WANG Shi-wei SHIMAI Shun-zo Shanghai Institute of Ceramics Chinese Academy of Science Shanghai 200050 China Graduate School of Chinese Academy of Science Beijing 100039 China

Porous silica ceramics has been prepared with the starch consolidation casting method. Slurries with various fractions of starch added in were prepared by ball-milling. The evaluation of the microstructures was done through two techniques： Hg porosimetry and SEM investigation. The bending strength of the sintered samples varied within the range of 10 MPa-20 MPa and the low dielectric constant within the range of 2.0-2.4 correspondent with the porosity of 42%-56%. The ceramics holds a brilliant promise of being a kind of core material used in sandwich-like electromagnetic windows.

关键词： porous ceramics SiO2 starch consolidation casting bending strength dielectric properties

NMR Studies of 3-Acylcamphor

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Chinese Chemical Letters 2000年第3期11卷 259-260页

作者： Li, ZN Liu, XM Zheng, zo Chen, HL Han, XW Chinese Acad Sci Dalian Inst Chem Phys Dalian 116023 Peoples R China

NMR studies of some chiral 3-acyclcamphor were Conducted. A complete assignment was given to 3-(4-pyridyl)carbonylcamphor by the 2D NMR technology. Assignments were also given to other beta-diketones. The results show... 详细信息

关键词： NMR 3-(4-pyridyl)carbonylcamphor acylcamphor beta-diketone

On the analytical soliton approximations to fractional forced Korteweg-de Vries equation arising in fluids and plasmas using two novel techniques

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Communications in Theoretical Physics 2024年第8期76卷 1-10页

作者： Weaam Alhejaili Emad A Az-zo’bi Rasool Shah S A El-Tantawy Department of Mathematical Sciences College of SciencePrincess Nourah bint Abdulrahman UniversityPO Box 84428Riyadh 11671Saudi Arabia Department Mathematics and Statistics Mutah UniversityAl-KarakJordan Department of Computer Science and Mathematics Lebanese American UniversityBeirutLebanon Department of Physics Faculty of SciencePort Said UniversityPort Said 42521Egypt Department of Physics Faculty of ScienceAl-Baha UniversityAl-Baha P.O.Box 1988Saudi Arabia

The current investigation examines the fractional forced Korteweg-de Vries(FF-KdV) equation,a critically significant evolution equation in various nonlinear branches of science. The equation in question and other associated equations are widely acknowledged for their broad applicability and potential for simulating a wide range of nonlinear phenomena in fluid physics, plasma physics, and various scientific domains. Consequently, the main goal of this study is to use the Yang homotopy perturbation method and the Yang transform decomposition method, along with the Caputo operator for analyzing the FF-KdV equation. The derived approximations are numerically examined and discussed. Our study will show that the two suggested methods are helpful, easy to use, and essential for looking at different nonlinear models that affect complex processes.

关键词： forced fractional KdV equation Caputo operator Yang homotopy perturbation method Yang transform decomposition method solitons

A Simple Game for the Study of Trust in Distributed Systems

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Wuhan University Journal of Natural Sciences 2001年第Z1期6卷 72-82页

作者： Biography: zoe zoe Diamadi, Michael J. Fischer Department of Computer Science, Yale University, New Haven CT 06520 8285,USA Department of Computer Science Yale University New Haven CT 06520-8285 USA

Trust is an important aspect of the design and analysis of secure distributed systems. It is often used informally to designate those portions of a system that must function correctly in order to achieve the desired outcome. But it is a notoriously diffcult notion to formalize. What are the properties of trust? How is it learned, propagated, and utilized successfully? How can it be modeled? How can a trust model be used to derive protocols that are effcient and reliable when employed in today's expansive networks? Past work has been concerned with only a few of these issues, without concentrating on the need for a comprehensive approach to trust modeling. In this paper, we take a first step in that direction by studying an artificial community of agents that uses a notion of trust to succeed in a game against nature. The model is simple enough to analyze and simulate, but also rich enough to exhibit phenomena of real life interactive communities. The model requires agents to make decisions. To do well, the agents are informed by knowledge gained from their own past experience as well as from the experience of other agents. Communication among agents allows knowledge to propagate faster through the network, which in turn can allow for a more successful community. We analyze the model from both a theoretical and an experimental point of view.

关键词： agent algorithm artificial society trust

Long-term high fructose and saturated fat diet affects plasma fatty acid profile in rats

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012年第4期13卷 307-317页

作者： Fabrice TRANCHIDA Léopold TCHIAKPE zo RAKOTONIAINA Valérie DEYRIS Olivier RAVION Abel HIOL Institute of Molecular Sciences of Marseilles iSm2 UMR 7313CNRSAix-Marseille University13397 Marseilles Cedex 20France Laboratory of Nutrition-Dietetics Faculty of PharmacyAix-Marseille University13385 Marseilles Cedex 5France Food Sciences Department of Biotechnology EngineeringInstitute of TechnologyUniversity of the French West Indies and GuianaSaint-Claude 97120France

As the consumption of fructose and saturated fatty acids(FAs) has greatly increased in western diets and is linked with an increased risk of metabolic syndrome,the aim of this study was to investigate the effects of a mod-erate(10 weeks) and a prolonged(30 weeks) high fructose and saturated fatty acid(HFS) diet on plasma FA com-position in *** effects of a few weeks of HFS diet had already been described,but in this paper we tried to es-tablish whether these effects persist or if they are modified after 10 or 30 *** hypothesized that the plasma FA profile would be altered between 10 and 30 weeks of the HFS *** fed with either the HFS or a standard diet were tested after 10 weeks and again after 30 *** 10 weeks of feeding,HFS-fed rats developed the metabolic syndrome,as manifested by an increase in fasting insulinemia,total cholesterol and triglyceride levels,as well as by impaired glucose ***,the plasma FA profile of the HFS group showed higher proportions of monounsaturated FAs like palmitoleic acid [16:1(n-7)] and oleic acid [18:1(n-9)],whereas the proportions of some polyunsaturated n-6 FAs,such as linoleic acid [18:2(n-6)] and arachidonic acid [20:4(n-6)],were lower than those in the control *** 30 weeks of the HFS diet,we observed changes mainly in the levels of 16:1(n-7)(decreased) and 20:4(n-6)(increased).Together,our results suggest that an HFS diet could lead to an adaptive response of the plasma FA profile over time,in association with the development of the metabolic syndrome.

关键词： High fructose and saturated fatty acid diet Metabolic syndrome Plasma fatty acids Adaptive response Rats