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社区2型糖尿病患者自我管理行为及对血糖控制的影响研究

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中国初级卫生保健 2024年第5期38卷 18-22页

作者：张崇威张紫阳林雅粒虞静雯莫倩莹贯力文吴肖冰汕头大学公共卫生学院广东汕头515041 深圳市慢性病防治中心广东深圳518020

目的:了解社区2型糖尿病患者的自我管理行为及其对血糖控制的影响,为相关部门进一步完善社区糖尿病健康教育与干预策略提供参考依据。方法:2022年7—12月,选取深圳市社区健康服务中心管理的2型糖尿病患者进行问卷调查,调查内容包括一般... 详细信息

目的:了解社区2型糖尿病患者的自我管理行为及其对血糖控制的影响,为相关部门进一步完善社区糖尿病健康教育与干预策略提供参考依据。方法:2022年7—12月,选取深圳市社区健康服务中心管理的2型糖尿病患者进行问卷调查,调查内容包括一般情况、糖尿病自我管理行为和血糖控制情况。结果:923例调查对象的合理用药、合理饮食和体育锻炼平均得分分别为(6.78±1.08)分、(5.88±2.28)分和(5.49±2.65)分,而血糖监测、检查足部和遵医嘱监测的平均得分均低于2分。糖化血红蛋白控制达标率为48.77%。多因素logistic回归分析结果显示,病程>5年、有吸烟行为、未配备血糖仪、使用胰岛素、较少或无合理饮食的患者糖化血红蛋白控制更难达标。结论:社区2型糖尿病患者在合理用药、合理饮食和体育锻炼上表现较好,而在血糖监测、遵医嘱监测和检查足部行为上表现较差。合理膳食是控制患者血糖达标的重要影响因素。相关部门应进一步规范社区家庭医生对糖尿病患者自我管理知识的健康指导,提升患者的自我管理能力,从而促使患者血糖水平达标。

关键词： 2型糖尿病自我管理糖化血红蛋白血糖控制

Co-alteration of Myc and RTK-RAS pathways defines a liver-metastatic propensity and immune-cold subgroup of pancreatic adenocarcinoma

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Genes & Diseases 2024年第3期11卷 47-50页

作者： Yuyuan zhang ziyang Zu Hui Xu Siyuan Weng Yuqing Ren Quan Cheng Peng Luo Jian zhang Zaoqu Liu Xinwei Han Department of Interventional Radiology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan450052China Interventional Institute of Zhengzhou University ZhengzhouHenan450052China Interventional Treatment and Clinical Research Center of Henan Province ZhengzhouHenan 450052China Department of Hepatobiliary and Pancreatic Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450052China Department of Respiratory and Critical Care Medicine The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan450052China Department of Neurosurgery Xiangya HospitalCentral South UniversityChangshaHunan 410008China Department of Oncology Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong 510280China

Co-altered pathways refer to the phenomenon where multiple biological pathways exhibit aberrant changes simultaneously within the same tumor sample.This phenomenon can facilitate a better understanding of the mechanism and evolution of tumors and serve as a biological marker for diagnosing,classifying,and treating tumors.1 However,the nature of alteration occurrence and the impact on pancreatic adenocarcinoma(PAAD)remain elusive.The SELECT algorithm was originally designed to systematically assess the evolutionary dependencies and their impact between altered genes in cancer for anticipating drug resistance and proposing alternative strategies.Here,to better characterize the etiology of PAAD and develop an improved risk assessment strategy,2 by utilizing SELECT,we identified a co-altered pathway subgroup of PAAD that demonstrated an elevated risk for unfavorable prognosis,a propensity for liver metastasis,and an immunologically cold microenvironment.

关键词： adenocarcinoma elevated alteration

两种不同平台单髁置换术对内侧单间室膝骨性关节炎短期疗效比较

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宁夏医科大学学报 2024年第3期46卷 271-275页

作者：陈德胜杨绿林王胤斌张梓炀马涛龚文涛宁夏回族自治区人民医院骨科宁夏医科大学第三临床医学院银川750002

目的观察活动平台与固定平台单髁置换术对膝骨性关节炎手术治疗的短期疗效。方法选取内侧单间室膝骨关节炎患者155例,均行人工单髁置换术,其中97例选择美国邦美Oxford第三代活动平台(mobilebearing,MB)单髁假体,58例选择德国LINK固定平... 详细信息

目的观察活动平台与固定平台单髁置换术对膝骨性关节炎手术治疗的短期疗效。方法选取内侧单间室膝骨关节炎患者155例,均行人工单髁置换术,其中97例选择美国邦美Oxford第三代活动平台(mobilebearing,MB)单髁假体,58例选择德国LINK固定平台(fixed-bearing,FB)单髁假体。比较两组手术时间及术中出血量;术前及术后1周、1个月视觉模拟评分(VAS);术前及术后1个月、3个月、6个月膝关节活动度(range of motion,ROM)及美国特种外科医院(hospital for special surgery,HSS)评分,并进行统计学分析。结果MB组与FB组手术时间及术中出血量比较差异均无统计学意义(P均>0.05)。术前、术后1周及术后1个月VAS评分差异均无统计学意义(P均>0.05),术前及术后1个月、3个月、6个月两组间ROM、HSS评分及术后6个月内并发症发病率差异均无统计学意义(P均>0.05)。结论MB和FB单髁置换术在膝骨性关节炎中短期疗效差异无统计学意义,MB单髁假体术后易出现假体脱位。

关键词：膝骨性关节炎单髁置换术活动平台固定平台

Strain Induced Rashba Splitting in CH3NH3PbBr3 organic-inorganic lead halide Perovskite

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Strain Induced Rashba Splitting in CH3NH3PbBr3 organic-inorg...

Four-function model analysis of nonsuicidal self-injury-related posts on Sina Weibo

第七届新型太阳能电池材料科学与技术学术研讨会

作者： Xianzhong Zhou ziyang zhang School of Information Engineering Guangdong University of Technology

In this work,the stain induced Rashba band splitting have been investigated by means of density functional theory in details.During the calculation,the lattice constant of CHNHPbBr(MAPbBr) varies from 5.4 to 6.4 ? including the spin-orbit coupling with full-relativistic pseudopotential.The band structure of various lattice constant of MAPbBr has been further extracted from the density functional theory,which is shown in Fig.1.The results show that the Rashba band splitting is anisotropy along different direction and the Rashba coefficient can be induced by strain.As the lattice constant become larger,the Rashba coefficient gradually reduced to near zero.On contrast,the Rashba coefficient become larger and larger when the lattice constant reduced.Therefore,the Rashba band splitting can be induced by strain.Besides,the anisotropy of Rashba band splitting become seriously as the strain become larger.Such results can help us better understand the mechanism of the Rashba band splitting in MAPbBr.

关键词： perovksite

来源： cnki会议评论

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General Psychiatry 2024年第1期37卷 168-172页

作者： Kexin zhang ziyang Wang Xin Yu Peking University Sixth Hospital BeijingChina Department of Industrial EngineeringandManagement Peking University College of EngineeringBeijingChina institute of Mental Health Peking University Sixth HospitalBeijingChina

To the editor:Non-suicidal self-injury(NSSI)is defined as direct,repetitive self-injury to bodily tissues without suicidal intent. The estimated prevalence of NsSI among adolescents is 17.2%worldwide with a comparable rate observed in China. As a behavioural addiction, NSSI poses a significant suicide risk,and is emerging as a major mental health problem among adolescents.To unravel this puzzle,the four-function model(FFM)distinguishes between interpersonal and intrapersonal functions,as well as positive and negative reinforcement functions,proving relatively comprehensive among various theoretical models.

关键词： function behaviour analysis

Tunable quantum dots in monolithic Fabry-Perot microcavities for high-performance single-photon sources

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Light(Science & Applications) 2024年第2期13卷 325-332页

作者： Jiawei Yang Yan Chen Zhixuan Rao ziyang Zheng Changkun Song Yujie Chen Kaili Xiong Pingxing Chen Chaofan zhang Wei Wu Ying Yu Siyuan Yu State Key Laboratory of Optoelectronic Materials and Technologies School of Electronics and Information TechnologySun Yat-Sen UniversityGuangzhou 510006China Institute for Quantum Science and Technology College of ScienceNational University of Defense TechnologyChangsha 410073China College of Advanced Interdisciplinary Studies National University of Defense TechnologyChangsha 410073China Hunan Key Laboratory of Quantum Information Mechanism and Technology National University of Defense TechnologyChangsha 410073 HunanChina Hefei National Laboratory Hefei 230088China

Cavity-enhanced single quantum dots(QDs)are the main approach towards ultra-high-performance solid-state quantum light sources for scalable photonic quantum technologies.Nevertheless,harnessing the Purcell effect requires precise spectral and spatial alignment of the QDs’emission with the cavity mode,which is challenging for most cavities.Here we have successfully integrated miniaturized Fabry-Perot microcavities with a piezoelectric actuator,and demonstrated a bright single-photon source derived from a deterministically coupled QD within this microcavity.Leveraging the cavity-membrane structures,we have achieved large spectral tunability via strain tuning.On resonance,a high Purcell factor of~9 is attained.The source delivers single photons with simultaneous high extraction efficiency of 0.58,high purity of 0.956(2)and high indistinguishability of 0.922(4).Together with its compact footprint,our scheme facilitates the scalable integration of indistinguishable quantum light sources on-chip,therefore removing a major barrier to the development of solid-state quantum information platforms based on QDs.

关键词： quantum removing purity

3D printedβ-sheet-reinforced natural polymer hydrogel bilayer tissue engineering scaffold

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Science China(Technological Sciences) 2024年第4期67卷 1170-1184页

作者： ZHAO XinRui NIE XiongFeng zhang XiaoPing SUN YaGe YANG Rong BIAN XinYu zhang Qian WANG HongYing XU ziyang LIU WenGuang School of Materials Science and Engineering Tianjin Key Laboratory of Composite and Functional MaterialsTianjin UniversityTianjin 300350China

It remains a significant challenge to fabricate natural polymer(NP)hydrogels with anti-swelling ability and high strengths in the physiological environment.Herein,theβ-sheet-reinforced NP hydrogel is developed by copolymerizing methacrylated gelatin(GelMA)and methacrylated silk fibroin(SFMA)in aqueous solution,followed by ethanol treatment(named GelMA-SFMAAL).Theβ-sheets formed by SFMA can act as a stable physical crosslink to enhance the mechanical properties and prolong the degradation of the GelMA network.Importantly,the chemical crosslinking in the GelMA-SFMA hydrogel prevents excessive aggregation of hydrophobicβ-sheets,thereby avoiding the formation of brittle hydrogel.The obtained GelMA-SFMA-AL hydrogels exhibit considerably enhanced mechanical properties(Young's modulus:0.89–3.68 MPa;tensile strength:0.31–0.96 MPa;toughness:0.09–0.63 MJ/m^(3);compressive modulus:0.78–2.20 MPa;compressive strength:2.65–5.93 MPa)compared with GelMA-SFMA hydrogels(Young's modulus:0.04–0.13 MPa;tensile strength:0.04–0.07 MPa;toughness:0.01–0.02 MJ/m^(3);compressive modulus:0.03–0.09 MPa;compressive strength:0.30–0.64 MPa).A bilayer osteochondral scaffold is constructed via digital light processing(DLP)three-dimensiaonl(3D)printing technology,comprising GelMA-SFMA@diclofenac sodium(DS)-AL as the top layer and GelMA-SFMA@bioactive glass(BG)-AL as the bottom layer.The bilayer hydrogel scaffold is demonstrated to support cell attachment and spreading,and facilitate osteogenic differentiation of rat bone marrow stem cells in vitro.In vivo implantation experiment suggests this bilayer scaffold is promising to be used for osteochondral tissue regeneration.

关键词： silk fibroin β-sheet high-strength hydrogel natural polymer osteochondral regeneration

Thermal comfort in a building with Trombe wall integrated with phase change materials in hot summer and cold winter region without air conditioning

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Energy and Built Environment

Energy and Built Environment 2024年第1期5卷 58-69页

作者： Jie Li Yuan zhang ziyang Zhu Jiangtian Zhu Jing Luo Fen Peng Xiaoqin Sun School of Energy and Power Engineering Changsha University of Science and TechnologyChangshaHunan 410114PR China

Trombe wall and phase change materials(PCMs)are two effective ways to regulate indoor thermal comfort.However,Trombe wall surfers from overheating in summer and PCMs suffer from low heat transfer rate caused by the limited thermal conductivity.To compensate the shortcomings of the two methods,this paper proposed a Trombe wall system integrated with PCMs.Based on a light-weight building envelope in Changsha,China,the thermal comfort of 10 kinds of Trombe wall systems with PCMs with a melting temperature of 18-28℃ were studied.Taking the integrated indoor discomfort duration(I_(D)),integrated indoor discomfort degree-hour(I_(DH)),indoor air temperature(T_(in)),PCM liquid fraction(γ)and heat flux across wall(q)as evaluation indexes,the indoor thermal comfort was assessed in hot summer and cold winter region.Results show that the Trombe wall helped PCMs complete the phase change process effectively.Trombe wall with PCM25 next to the wall inner surface possessed the lowest annual I_(D) and I_(DH),as 2877 h and 12,974℃·h,respectively.Compared with the values in a traditional building,the I_(D) and I_(DH) were reduced by 7.01% and 14.14%.In order to give full play to the heat storage and heat release of the Trombe wall with PCMs,PCMs with phase change temperature 7℃ lower than the peak ambient temperature in summer or 8℃ higher than the winter night temperature was recommended according to regional climate conditions.

关键词： Trombe wall Phase change materials Integrated indoor discomfort duration Integrated discomfort degree-hour Liquid fraction

Assembly Variation Identification of High Pressure Spool by Response Surface Based Model Updating Using IV-optimal Designs

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Chinese Journal of Aeronautics 2012年第5期25卷 817-824页

作者： zhang ziyang XIE Shousheng HU Jinhai MIAO Zhuoguang WANG Lei The Engineering Institute Air Force Engineering UniversityXi'an 710038China

This article, in order to improve the assembly of the high-pressure spool, presents an assembly variation identification method achieved by response surface method （RSM）-based model updating using IV-optimal designs. The method involves screening out non-relevant assembly parameters using IV-optimal designs and the preload of the joints is chosen as the input features and modal frequency is the only response feature. Emphasis is placed on the construction of response surface models including the interactions between the bolted joints by which the non-linear relationship between the assembly variation caused by the changes ofpreload and the output frequency variation is established. By achieving an optimal process of selected variables in the model, assembly variation can be identified. With a case study of the laboratory bolted disks as an example, the proposed method is verified and it gives enough accuracy in variation identification. It has been observed that the first-order response surface models considering the interactions between the bolted joints based on the IV-optimal criterion are adequate for assembly purposes.

关键词： high-pressure spool bolted joints response surface method identification of assembly variation model updating IV-optimal designs