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基于弹性秘密共享的多方洗牌协议

信息安全研究 2024年第4期10卷 347-352页

作者：满子琪张艳硕严梓洋罗乐琦陈颖北京电子科技学院北京100070

为了促进对数据隐私的保护,提出了一种基于弹性秘密共享的多方洗牌协议,主要采用了弹性秘密共享、洗牌协议与隐私集合交集计算技术.首先对基于弹性秘密共享的多方洗牌协议及其相关技术进行了简要的介绍,紧接着对模型、框架进行了构建,... 详细信息

为了促进对数据隐私的保护,提出了一种基于弹性秘密共享的多方洗牌协议,主要采用了弹性秘密共享、洗牌协议与隐私集合交集计算技术.首先对基于弹性秘密共享的多方洗牌协议及其相关技术进行了简要的介绍,紧接着对模型、框架进行了构建,并提出了基于弹性秘密共享的多方洗牌协议的设计方案.同时,对该协议的正确性、安全性、性能、应用前景进行了详细分析.通过有关定理的证明以及与一些方案的对比分析,该协议具有较高的效率以及较好的安全性.

关键词：弹性秘密共享洗牌协议隐私集合交集计算隐私保护密码学

Flash sintering of high-purity alumina at room temperature

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Journal of Advanced Ceramics 2023年第12期12卷 2382-2388页

作者： Yueji Li Qingguo Chi ziyang yan Nianping yan Jinling Liu Rongxia Huang Xilin Wang Engineering Laboratory of Power Equipment Reliability in Complicated Coastal Environments Tsinghua Shenzhen International Graduate SchoolTsinghua UniversityShenzhen 518055China Key Laboratory of Engineering Dielectrics and Its Application Ministry of EducationHarbin University of Science and TechnologySchool of Electrical and Electronic EngineeringHarbin University of Science and TechnologyHarbin 150080China State Grid Tianjin Chengxi Electric Power Supply Company Tianjin 300113China State Grade Jiangxi Electric Power Research Institute Nanchang 330096China School of Mechanics and Aerospace Engineering Southwest Jiaotong University Chengdu 611756China School of Electromechanical Engineering Guangdong University of TechnologyGuangzhou 510006China

For the first time,the flash sintering(FS)of high-purity alumina at room temperature,which was previously considered unachievable due to its low electrical conductivity,was conducted *** electrical arc originating from surface flashover was harnessed to induce FS at room temperature and low air *** successful FS of high-purity alumina was realized at 60 kPa under the arc constraint,resulting in a notable relative density of the alumina sample of 98.7%.The electric–thermal coupling between the arc and high-purity alumina sample during the arc-induced FS process was analyzed via the finite element simulation *** results revealed the thermal and electrical effects of the arc on the sample,which ultimately enhance the electrical conductivity of the alumina *** formation of a conductive channel on the sample surface,a result of increased electrical conductivity,was the pivotal factor in achieving FS in high-purity alumina at room *** arc constraint technique can be applied to numerous materials,such as ionic conductors,semiconductors,and even insulators,under room-temperature and low-air-pressure conditions.

关键词： flash sintering(FS) high-purity alumina arc constraint electric-thermal coupling simulation

Effect of chimney shadow on the performance of wind supercharged solar chimney power plants:A numerical case study for the Spanish prototype

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Global Energy Interconnection 2021年第4期4卷 405-414页

作者： Lu Zuo Pengzhan Dai Ling Ding ziyang yan Xinru Wang Jiachen Li College of Energy and Electrical Engineering Hohai UniversityNanjing 210098P.R.China Shanghai Electric Group Company Limited Shanghai 200122P.R.China

Three-dimensional numerical simulations for a solar chimney power plant(SCPP)and wind supercharged solar chimney power plant(WSSCPP)based on the Spanish prototype using the solar ray-tracing algorithm were performed to study the shadow effect of the *** area of the shadow region increases with an increase in the incident angle of the solar rays.A parametric study was performed by varying the incident angle from 0°to 30°.The temperature and velocity distributions at different incident angles were *** addition,we investigated the chimney shadow effect in several comprehensive SCPP *** findings show that the turbine shaft powers of the SCPP and WSSCPP were reduced by 22.4%and 13.7%,respectively,when the incident angle increased from 0°to 30°.In conclusion,it is important to consider the chimney shadow effect when estimating the performance in the design and cost analysis of SCPP systems.

关键词： Solar chimney Shadow effect Wind pressure ventilator Turbine Solar ray-tracing algorithm

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基于对比分析的密码安全协议课程案例化设计

北京电子科技学院学报 2024年第1期32卷 82-94页

作者：张艳硕袁煜淇严梓洋谢绒娜北京电子科技学院北京市100070

密码安全协议,又称密码协议,是基于密码学的消息交换协议,旨在网络环境中提供各种安全服务。该协议确保了通信中数据的保密性、完整性和可靠性,是密码学分支学科中涉及计算机网络、通信系统和信息安全领域的技术和方法。其目标是防止数... 详细信息

密码安全协议,又称密码协议,是基于密码学的消息交换协议,旨在网络环境中提供各种安全服务。该协议确保了通信中数据的保密性、完整性和可靠性,是密码学分支学科中涉及计算机网络、通信系统和信息安全领域的技术和方法。其目标是防止数据在传输过程中受到恶意篡改、窃取或伪造的威胁。由于密码安全协议涉及抽象概念的理解、高数学基础的要求以及实验环境和工具的限制等难点,教学内容和讲授方法一直是该领域的重要研究问题。本文基于对比分析法,提出了层次结构化的密码安全协议案例化教学设计,通过典型教学案例来深入剖析密码安全协议课程的学习,以加深学生对课程内容的理解和应用。

关键词：密码安全协议对比分析教学设计人才培养案例

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南方医科大学学报 2024年第5期44卷 818-826页

作者：崔芝马萃娇王倩茹陈金豪严子阳杨建林吕亚丰曹春雨肿瘤微环境与免疫治疗湖北省重点实验室三峡大学基础医学院湖北宜昌443002

目的研究腺相关病毒(AAV2)介导的TGF-βⅡ受体(TβRⅡ)胞外结构域和IgG2a Fc段融合基因对小鼠4T1细胞在体内增殖和迁移的影响。方法通过分子克隆构建表达sTβRⅡ-Fc的腺相关病毒核心质粒载体pAAV-sTβRⅡ-Fc,转染至HEK 293T细胞验证分泌... 详细信息

目的研究腺相关病毒(AAV2)介导的TGF-βⅡ受体(TβRⅡ)胞外结构域和IgG2a Fc段融合基因对小鼠4T1细胞在体内增殖和迁移的影响。方法通过分子克隆构建表达sTβRⅡ-Fc的腺相关病毒核心质粒载体pAAV-sTβRⅡ-Fc,转染至HEK 293T细胞验证分泌性sTβRⅡ的表达。在HEK 293T细胞中共转染重组腺相关病毒核心质粒pAAV-sTβRⅡ-Fc、衣壳蛋白表达质粒pAAV2和辅助质粒pHelper以制备AAV2-sTβRⅡ,碘克沙醇密度梯度离心法纯化病毒。Western blot检测AAV2-sTβRⅡ对TGF-β信号通路下游关键蛋白Smad2/3磷酸化水平的影响,以及经治疗后各组小鼠4T1移植瘤内E-钙黏蛋白、波形蛋白、p-Smad2/3的表达水平。构建Luciferase标记的4T1细胞并荷瘤BALB/c小鼠,荷瘤小鼠随机分为处理组AAV2-sTβRⅡ、对照组AAV2-GFP和溶剂对照组PBS(6只/组),各组病毒均经尾静注射到小鼠体内。小动物活体成像观察AAV2-sTβRⅡ在小鼠体内对4T1移植瘤增殖的影响。免疫组织化学检测肿瘤组织Ki67蛋白的表达水平。免疫荧光检测小鼠肝脏内sTβRⅡ蛋白的表达水平。H&E染色观察小鼠肺部肿瘤转移灶和主要脏器的病理学改变。结果pAAV-sTβRⅡ-Fc重组质粒构建成功并在HEK 293T细胞中分泌表达sTβRⅡ。AAV2-sTβRⅡ能够感染4T1细胞并显著降低TGF-β1诱导的Smad2/3蛋白磷酸化(P0.05)。结论重组腺相关病毒载体AAV2介导的TβRⅡ胞外结构域编码序列,可阻断4T1细胞中的TGF-β信号通路,显著抑制小鼠体内4T1细胞增殖和肺转移。

关键词：三阴性乳腺癌 TGF-βⅡ 迁移 TGF-β信号通路腺相关病毒

A process insight into production of ethyl levulinate via a stepwise fractionation

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Journal of Bioresources and Bioproducts 2024年第2期9卷 233-242页

作者： yan Ma Hongxiao Wang ziyang Wu Weihong Tan Guodong Feng Jianchun Jiang Institute of Chemical Industry of Forest Products Chinese Academy of ForestryNanjing 210042China Jiangsu Province Key Lab.of Biomass Energy and Material Nanjing 210042China National Engineering Lab.for Biomass Chemical Utilization Nanjing 210042China Co-Innovation Center of Efficient Processing and Utilization of Forest Resources Nanjing Forestry UniversityNanjing 210037China

Ethyl levulinate(EL)is a key biomass-derived compounds due to its socio-economic benefits for the synthesis of commodity ***,we proposed an efficient one-step bamboo conversion to EL in ethanol,and a novel stepwise fractionation to purify EL and lignocellulose degradation products.A proton acid,due to its high catalytic efficiency,yielded 26.65%EL in 120 min at 200℃.The productions of ethyl glucoside and 5-ethoxymethylfurfural were analyzed in terms of by-products *** the best of our knowledge,there is no single report on catalyst for one step synthesis of EL directly from bamboo,as well as a stepwise fractionation to purify *** to similar physiochemical properties in each fraction,the platform molecules could broaden a new paradigm of bamboo biomass utilization for renewable energy and value-added *** addition,glucose,ethyl glucoside,corn starch,and microcrystalline cellulose were also investigated as substrates,so that the reaction intermediates of this one-pot procedure were identified and a possible reaction mechanism was proposed.

关键词： Ethyl levulinate Liquefaction Biomass Ethanol By-products

Multi-omics integration reveals potential stage-specific druggable targets in T-cell acute lymphoblastic leukemia

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Genes & Diseases 2024年第5期11卷 374-389页

作者： Zijun yan Jie Xia ziyang Cao Hongyang Zhang Jinxia Wang Tienan Feng Yi Shu Lin Zou Clinical Research Unit Shanghai Children’s HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200062China Institute of Pediatric Infection Immunityand Critical Care MedicineShanghai Jiao Tong University School of MedicineShanghai 200062China Center for Clinical Molecular Laboratory Medicine of Children’s Hospital of Chongqing Medical University Chongqing 400014China Clinical Research Institute Shanghai Jiao Tong University School of MedicineShanghai 200025China Bioinformatics and BioMedical Bigdata Mining Laboratory School of Big HealthGuizhou Medical UniversityGuiyangGuizhou 554300China

T-cell acute lymphoblastic leukemia(T-ALL),a heterogeneous hematological malignancy,is caused by the developmental arrest of normal T-cell *** development of targeted therapeutic regimens is impeded by poor knowledge of the stage-specific aberrances in this *** this study,we performed multi-omics integration analysis,which included mRNA expression,chromatin accessibility,and gene-dependency database analyses,to identify potential stage-specific druggable targets and repositioned drugs for this *** multi-omics integration helped identify 29 potential pathological genes for *** genes exhibited tissue-specific expression profiles and were enriched in the cell cycle,hematopoietic stem cell differentiation,and the AMPK signaling *** these,four known druggable targets(CDK6,TUBA1A,TUBB,and TYMS)showed dysregulated and stage-specific expression in malignant T cells and may serve as stage-specific targets in *** TUBA1A expression level was higher in the early T cell precursor(ETP)-ALL cells,while TUBB and TYMS were mainly highly expressed in malignant T cells arrested at the CD4 and CD8 double-positive or single-positive ***6 exhibited a U-shaped expression pattern in malignant T cells along the naıve to maturation ***,mebendazole and gemcitabine,which target TUBA1A and TYMS,respectively,exerted stage-specific inhibitory effects on T-ALL cell lines,indicating their potential stage-specific antileukemic role in ***,our findings might aid in identifying potential stage-specific druggable targets and are promising for achieving more precise therapeutic strategies for T-ALL.

关键词： Multi-omics Stage-specific druggable targets Targeted therapeutic strategies T-cell acute lymphoblastic leukemia Drug repositioning

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枸杞开花生物学及传粉特征研究

中国农业科技导报 2024年第9期26卷 34-43页

作者：万云星闫自杨姚军郭立明朱金忠唐建宁乔彩云匡海鸥龚雪阳岳丹赵文正云南农业大学动物科学技术学院昆明650201 中国农业科学院蜜蜂研究所北京100091 宁夏林业调查规划院银川750010 宁夏杞鑫种业有限公司宁夏中卫755102 宁夏枸杞产业发展中心银川750000

授粉不足是导致枸杞落花落果的直接原因之一,为了解枸杞的生殖生物学特点,以‘宁杞10号’为研究材料,测定其花期不同阶段的花部色态、柱头可授性和花粉活力等开花特性及泌蜜规律,并对其常见传粉昆虫的单次访花时长、柱头花粉沉降数等传... 详细信息

授粉不足是导致枸杞落花落果的直接原因之一,为了解枸杞的生殖生物学特点,以‘宁杞10号’为研究材料,测定其花期不同阶段的花部色态、柱头可授性和花粉活力等开花特性及泌蜜规律,并对其常见传粉昆虫的单次访花时长、柱头花粉沉降数等传粉特征进行分析。结果表明,在开花后12~24 h,花瓣颜色变为浅紫色和白紫色时,柱头可授性、花粉活力和泌蜜量均最高,相比其他几个阶段差异显著(P蜜蜂>无垫蜂)与自然传粉相比差异显著,蜜蜂对紫色花的访花时长均值为4.1 s,与对黄色花的访花时长(均值为1.7 s)相比差异极显著(P<0.01);从整体效率和传粉昆虫访问数量而言,建议引入传粉昆虫(如蜜蜂)以加强枸杞辅助授粉,提高枸杞的坐果结实率。研究结果为制定枸杞辅助授粉措施提供科学依据。

关键词：宁夏枸杞柱头可授性花粉活力泌蜜规律访花时长单次传粉量

Tunable quantum dots in monolithic Fabry-Perot microcavities for high-performance single-photon sources

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Light(Science & Applications) 2024年第2期13卷 325-332页

作者： Jiawei yang yan Chen Zhixuan Rao ziyang Zheng Changkun Song Yujie Chen Kaili Xiong Pingxing Chen Chaofan Zhang Wei Wu Ying Yu Siyuan Yu State Key Laboratory of Optoelectronic Materials and Technologies School of Electronics and Information TechnologySun Yat-Sen UniversityGuangzhou 510006China Institute for Quantum Science and Technology College of ScienceNational University of Defense TechnologyChangsha 410073China College of Advanced Interdisciplinary Studies National University of Defense TechnologyChangsha 410073China Hunan Key Laboratory of Quantum Information Mechanism and Technology National University of Defense TechnologyChangsha 410073 HunanChina Hefei National Laboratory Hefei 230088China

Cavity-enhanced single quantum dots(QDs)are the main approach towards ultra-high-performance solid-state quantum light sources for scalable photonic quantum ***,harnessing the Purcell effect requires precise spectral and spatial alignment of the QDs’emission with the cavity mode,which is challenging for most *** we have successfully integrated miniaturized Fabry-Perot microcavities with a piezoelectric actuator,and demonstrated a bright single-photon source derived from a deterministically coupled QD within this *** the cavity-membrane structures,we have achieved large spectral tunability via strain *** resonance,a high Purcell factor of~9 is *** source delivers single photons with simultaneous high extraction efficiency of 0.58,high purity of 0.956(2)and high indistinguishability of 0.922(4).Together with its compact footprint,our scheme facilitates the scalable integration of indistinguishable quantum light sources on-chip,therefore removing a major barrier to the development of solid-state quantum information platforms based on QDs.

关键词： quantum removing purity