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Fasn involved in the nephrotoxicity induced by polystyrene nanoplastics and the intervention of melatonin through intestinal microbiota-mediated lipid metabolism disorder

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Nano Research 2024年第8期17卷 7365-7375页

作者： Huiwen Kang Danyang Huang Jiaru Jing Wei Zhang Lei Zhang Jingyu Wang ziyan Liu Lin Han ziyan Wang Lefeng Zhang Ai Gao Department of Occupational Health and Environmental Health School of Public HealthCapital Medical UniversityBeijing 100069China Beijing Key Laboratory of Environmental Toxicology Capital Medical UniversityBeijing 100069China

Nanoplastics(NPs)can accumulate in the kidney and cause kidney injury,but the multi-organ interaction mechanism and preventive measures of kidney injury are still *** this study,in vivo(60μg/day,42 days)and in vitro(0.4μg/μL,24 h)exposure models of polystyrene nanoplastics(PS-NPs,80 nm)in mice and human kidney cortex proximal tubule epithelial cells(HK-2 cells)were established,*** study revealed that PS-NPs caused obvious pathological changes and impaired renal function in mice,which were related to lipid metabolism disorders mediated by intestinal ***-fatty acid synthase(Fasn)-docosahexaenoic acid(DHA)pathway may be one of the mechanisms of kidney injury in ***,we also found that melatonin attenuates PS-NPs-induced nephrotoxicity by modulating lipid metabolism disorders(represented by DHA)and affects Fasn *** conclusion,our study revealed the important role of intestinal flora-mediated lipid metabolism in PS-NPs-induced nephrotoxicity and preliminarily provided potential key gene targets and effective preventive measures for PS-NPs-induced nephrotoxicity.

关键词： nanoplastics nephrotoxicity lipid metabolism fatty acid synthase(Fasn) melatonin

REEs recovery from molten salt electrolytic slag:Challenges and opportunities for environmentally friendly techniques

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Journal of Rare Earths 2024年第6期42卷 1009-1019,I0001页

作者： ziyan Yang Faxin Xiao Shuchen Sun Heng Zhong Ganfeng Tu School of Metallurgy Northeastern UniversityShenyang110819China Key Laboratory for Recycling of Nonferrous Metal Resources(Shenyang) Shenyang110819China

Due to the unique physical and chemical properties,rare earth elements(REEs)play a significant role in the high-tech *** the past few decades,the rare earth reserve in China has been gradually decreasing and more pressure has been exerted on the global rare earth supply for the increasing demand of REEs,which indicates that it is essential to recycle secondary resources to meet the rare earth *** for rare earth molten salt electrolytic slag(REMES),although its high rare earth content has potential huge economic value,its high fluorine content of approximately 10 wt%-20 wt%can pollute the *** methods are used to treat *** metallurgical and pyro-hydrometallurgical methods have gotten a big success for solving most of the hydrometallurgical problems,while some problems,like long route and waste water,need to be *** distillation is a new and promising method with a short process due to its harmlessness and high efficiency,but has shortcomings such as high energy consumption and material *** review presents these above three treatment methods,and the challenges and chances of using the recovery technique of REMES in an environmentally friendly way.

关键词： Rare earths Molten salt electrolytic slag Hydrometallurgy Pyro-hydrometallurgy Vacuum distillation Recovery

Evolutionary Optimization Methods for High-Dimensional Expensive Problems:A Survey

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IEEE/CAA Journal of Automatica Sinica 2024年第5期11卷 1092-1105页

作者： MengChu Zhou Meiji Cui Dian Xu Shuwei Zhu ziyan Zhao Abdullah Abusorrah Department of Electrical and Computer Engineering New Jersey Institute of TechnologyNewarkNJ 07102 USA School of Information and Electronic Engineering Zhejiang Gongshang UniversityHangzhou 310018China School of Intelligent Manufacturing Nanjing University of Science and TechnologyNanjing 210094China Institute of Systems Engineering Macao University of Science and TechnologyMacao 999078China School of Artificial Intelligence and Computer Jiangnan UniversityWuxi 214122China School of Information Science and Engineering Northeastern UniversityShenyang 110819China Center of Research Excellence in Renewable Energy and Power Systems Department of Electrical and Computer EngineeringFaculty of EngineeringKing Abdulaziz UniversityJeddah 21589Saudi Arabia K.A.CARE Energy Research and Innovation Center King Abdulaziz UniversityJeddah 21589Saudi Arabia

Evolutionary computation is a rapidly evolving field and the related algorithms have been successfully used to solve various real-world optimization *** past decade has also witnessed their fast progress to solve a class of challenging optimization problems called high-dimensional expensive problems(HEPs).The evaluation of their objective fitness requires expensive resource due to their use of time-consuming physical experiments or computer ***,it is hard to traverse the huge search space within reasonable resource as problem dimension *** evolutionary algorithms(EAs)tend to fail to solve HEPs competently because they need to conduct many such expensive evaluations before achieving satisfactory *** reduce such evaluations,many novel surrogate-assisted algorithms emerge to cope with HEPs in recent *** there lacks a thorough review of the state of the art in this specific and important *** paper provides a comprehensive survey of these evolutionary algorithms for *** start with a brief introduction to the research status and the basic concepts of ***,we present surrogate-assisted evolutionary algorithms for HEPs from four main *** also give comparative results of some representative algorithms and application ***,we indicate open challenges and several promising directions to advance the progress in evolutionary optimization algorithms for HEPs.

关键词： computer optimization evolutionary

Stability-Considered Lane Keeping Control of Commercial Vehicles Based on Improved APF Algorithm

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Chinese Journal of Mechanical Engineering 2024年第1期37卷 114-129页

作者： Bin Tang Zhengyi Yang Haobin Jiang ziyan Lin Zhanxiang Xu Zitian Hu Automotive Engineering Research Institute Jiangsu UniversityZhenjiang 212013China

Regarding the lane keeping system,path tracking accuracy and lateral stability at high speeds need to be taken into account especially for commercial vehicles due to the characteristics of larger mass,longer wheelbase and higher mass *** improve the performance mentioned above comprehensively,the control strategy based on improved artificial potential field(APF)algorithm is *** the paper,time to lane crossing(TLC)is introduced into the potential field function to enhance the accuracy of path tracking,meanwhile the vehicle dynamics parameters including yaw rate and lateral acceleration are chosen as the repulsive force field *** lane keeping controller based on improved APF algorithm is designed and the stability of the control system is proved based on Lyapunov *** addition,adaptive inertial weight particle swarm optimization algorithm(AIWPSO)is applied to optimize the gain of each potential field *** co-simulation results indicate that the comprehensive evaluation index respecting lane tracking accuracy and lateral stability is reduced ***,the proposed control strategy is verified by the HiL *** provides a beneficial reference for dynamics control of commercial vehicles and enriches the theoretical development and practical application of artificial potential field method in the field of intelligent driving.

关键词： Lane keeping control Commercial vehicles Lateral stability Artificial potential field AIWPSO

A personalized electronic textile for ultrasensitive pressure sensing enabled by biocompatible MXene/ PEDOT:PSS composite

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Carbon Energy 2024年第3期6卷 224-238页

作者： Yahua Li Wentao Cao Zhi Liu Yue Zhang ziyan Chen Xianhong Zheng Department of Interventional Radiology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenanChina School of Textile and Garment Anhui Polytechnic UniversityWuhuAnhuiChina Department of Prosthodontics Shanghai Stomatological Hospital and School of StomatologyFudan UniversityShanghaiChina College of Chemistry Chemical Engineering and BiotechnologyDonghua UniversityShanghaiChina

Flexible,breathable,and highly sensitive pressure sensors have increasingly become a focal point of interest due to their pivotal role in healthcare monitoring,advanced electronic skin applications,and disease ***,traditional methods,involving elastomer film-based substrates or encapsulation techniques,often fall short due to mechanical mismatches,discomfort,lack of breathability,and limitations in sensing ***,there is a pressing need,yet it remains a significant challenge to create pressure sensors that are not only highly breathable,flexible,and comfortable but also sensitive,durable,and ***,we present a biocompatible and breathable fabric-based pressure sensor,using nonwoven fabrics as both the sensing electrode(coated with MXene/poly(3,4-ethylenedioxythiophene):polystyrene sulfonate[PEDOT:PSS])and the interdigitated electrode(printed with MXene pattern)via a scalable spray-coating and screen-coating *** resultant device exhibits commendable air permeability,biocompatibility,and pressure sensing performance,including a remarkable sensitivity(754.5 kPa^(−1)),rapid response/recovery time(180/110 ms),and robust cycling ***,the integration of PEDOT:PSS plays a crucial role in protecting the MXene nanosheets from oxidation,significantly enhancing the device's long-term *** outstanding features make this sensor highly suitable for applications in fullrange human activities detection and disease *** study underscores the promising future of flexible pressure sensors in the realm of intelligent wearable electronics,setting a new benchmark for the industry.

关键词： biocompatibility MXene pressure sensor screen printing textile

Cellulose nanofiber-coated delignified wood as an efficient filter for microplastic removal

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Progress in Natural Science:Materials International 2024年第1期34卷 162-171页

作者： Xinyue Liu Mei-Chun Li Yang Lu ziyan Li Chaozheng Liu Zhipeng Liu Changtong Mei Qinglin Wu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources College of Materials Science and Engineering Nanjing Forestry University School of Petroleum Engineering China University of Petroleum(East China) Key Laboratory of Unconventional Oil&Gas Development(China University of Petroleum(East China)) Ministry of Education School of Renewable Natural Resources Louisiana State University Ag Center

Microplastics（MPs） are a new type of emerging pollutant in the aquatic environment that pose a tremendous risk to aquatic organisms and human health. Although many studies have focused on the removal of MPs, most of the materials used are non-renewable, non-degradable, and relatively costly. The development of green, renewable,and cost-effective materials for the removal of MPs presents a significant challenge. In this work, cellulose nanofiber-coated, delignified wood（CNF-CDW） was prepared and used as an efficient filter to remove MPs for the first time. Balsa wood chip was delignified through three approaches using NaClO2, Na2SO3/NaOH, and a deep eutectic solvent（DES） consisting of choline chloride/lactic acid. Delignified wood（DW） with desirable mechanical properties and a high pore structure was successfully prepared by optimizing the delignification method and reaction conditions. Subsequently, the CNF-CDW was prepared through immersion of DW in a suspension of cellulose nanofiber（CNF）, followed by crosslinking with CaCl2solutions. The effects of CNF concentration, CaCl2concentration, and wood chip thickness on the removal efficiency and flux of CNF-CDW towards polystyrene（PS）MPs were systematically studied. Under the optimal conditions of 0.5 wt% CNF, 1 mol/L CaCl2, and 10 mm in thickness, the CNF-CDW exhibited superior MPs removal performance, with a removal efficiency of 95.97% and a flux of 1146 L/m2·h. Morphological analysis revealed that CNF formed compact films on the surface DW, and MPs were efficiently blocked both on the surface and internal cellular structure of CNF-CDW. Therefore, with its exceptional filtration efficiency, high flux, and sustainable nature, CNF-CDW has a broad application prospect in the field of removing MPs from aquatic environment, promoting a brighter and cleaner future for aquatic ecosystems and human well-being.

关键词： Cellulose nanofiber Wood Microplastic Filter Filtration efficiency

High Density 3D Carbon Tube Nanoarray Electrode Boosting the Capacitance of Filter Capacitor

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Nano-Micro Letters 2024年第11期16卷 242-254页

作者： Gan Chen Fangming Han Huachun Ma Pei Li ziyan Zhou Pengxiang Wang Xiaoyan Li Guowen Meng Bingqing Wei Key Laboratory of Materials Physics and Anhui Key Laboratory of Nanomaterials and NanotechnologyInstitute of Solid State PhysicsHFIPSChinese Academy of SciencesHefei 230031People’s Republic of China Department of Materials Science and Engineering University of Science and Technology of ChinaHefei 230026People’s Republic of China Department of Mechanical Engineering University of DelawareNewarkDE 19716USA Mechano‑X Institute Applied Mechanics LaboratoryDepartment of Engineering MechanicsTsinghua UniversityBeijing 100084People’s Republic of China

Electric double-layer capacitors(EDLCs)with fast frequency response are regarded as small-scale alternatives to the commercial bulky aluminum electrolytic *** carbon-based nanoarray electrodes with precise alignment and smooth ion channels is crucial for enhancing EDLCs’***,controlling the density of macropore-dominated nanoarray electrodes poses challenges in boosting the capacitance of line-filtering ***,a simple technique to finely adjust the vertical-pore diameter and inter-spacing in three-dimensional nanoporous anodic aluminum oxide(3D-AAO)template is achieved,and 3D compactly arranged carbon tube(3D-CACT)nanoarrays are created as electrodes for symmetrical EDLCs using nanoporous 3D-AAO template-assisted chemical vapor deposition of *** 3D-CACT electrodes demonstrate a high surface area of 253.0 m^(2) g^(−1),a D/G band intensity ratio of 0.94,and a C/O atomic ratio of *** a result,the high-density 3D-CT nanoarray-based sandwich-type EDLCs demonstrate a record high specific areal capacitance of 3.23 mF cm^(-2) at 120 Hz and exceptional fast frequency response due to the vertically aligned and highly ordered nanoarray of closely packed CT *** 3D-CT nanoarray electrode-based EDLCs could serve as line filters in integrated circuits,aiding power system miniaturization.

关键词： Compactly arranged Three-dimensional carbon tube nanoarray Dimensional carbon tube nanoarray Fast frequency response Electric double-layer capacitors Layer capacitors AC line-filtering Filtering

Targeted screening of an anti-inflammatory polypeptide from Rhopilema esculentum Kishinouye cnidoblasts and elucidation of its mechanism in alleviating ulcerative colitis based on an analysis of the gut microbiota and metabolites

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Food Science and Human Wellness 2024年第3期13卷 1336-1347页

作者： ziyan Wang Qiuyue Shi Ying Feng Jiaojiao Han Chenyang Lu Jun Zhou Zhonghua Wang Xiurong Su State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products Ningbo UniversityNingbo 315000China School of Marine Science Ningbo UniversityNingbo 315000China Key Laboratory of Aquaculture Biotechnology(Ningbo University) Ministry of EducationNingbo UniversityNingbo 315000China College of Life Sciences Tonghua Normal UniversityTonghua 134000China Shandong Beiyou Biotechnology Co. Ltd.Weifang 261000China

Ulcerative colitis(UC)is a recurrent inflammatory bowel disease that imposes a severe burden on families and *** recent years,exploiting the potential of marine bioactive peptides for the treatment of diseases has become a topic of intense research *** study revealed the mechanism underlying the protective effect of the dominant polypeptide PKKVV(Pro-Lys-Lys-Val-Val)of Rhopilema esculentum cnidoblasts against DSS-induced UC through a combined analysis of the metagenome and serum ***,the polypeptide composition of *** cnidoblasts was determined by matrix-assisted laser desorption ionization time-of-flight mass spectrometry(MALDI-TOF/TOF-MS).Molecular docking showed that the dominant peptide PKKVV could bind better with tumor necrosis factor-α(TNF-α)than the original *** animal experiments suggested that PKKVV could modulate disorganized gut microorganisms in mice with UC;affect serum metabolites through the arachidonic acid,glycerophospholipid and linoleic acid metabolism pathways;and further alleviate UC *** study provides a reference for the comprehensive development of marine bioactive substances and nonpharmaceutical treatments for UC.

关键词： Ulcerative colitis Rhopilema esculentum Kishinouye Cnidoblasts Marine bioactive polypeptides Metagenome Serum metabolome

Identifying multidisciplinary problems from scientific publications based on a text generation method

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Journal of Data and Information Science 2024年第3期9卷 213-237页

作者： ziyan Xu Hongqi Han Linna Li Junsheng Zhang Zexu Zhou Institute of Scientific and Technical Information of China Beijing 100038China

Purpose:A text generation based multidisciplinary problem identification method is proposed,which does not rely on a large amount of data ***/methodology/approach:The proposed method first identifies the research objective types and disciplinary labels of papers using a text classification technique;second,it generates abstractive titles for each paper based on abstract and research objective types using a generative pre-trained language model;third,it extracts problem phrases from generated titles according to regular expression rules;fourth,it creates problem relation networks and identifies the same problems by exploiting a weighted community detection algorithm;finally,it identifies multidisciplinary problems based on the disciplinary labels of ***:Experiments in the“Carbon Peaking and Carbon Neutrality”field show that the proposed method can effectively identify multidisciplinary research *** disciplinary distribution of the identified problems is consistent with our understanding of multidisciplinary collaboration in the *** limitations:It is necessary to use the proposed method in other multidisciplinary fields to validate its *** implications:Multidisciplinary problem identification helps to gather multidisciplinary forces to solve complex real-world problems for the governments,fund valuable multidisciplinary problems for research management authorities,and borrow ideas from other disciplines for ***/value:This approach proposes a novel multidisciplinary problem identification method based on text generation,which identifies multidisciplinary problems based on generative abstractive titles of papers without data annotation required by standard sequence labeling techniques.

关键词： Problem identification Multidisciplinary Text generation Text classification