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Innovation leading development:a glimpse into three-dimensional bioprinting in Israel

Bio-Design and Manufacturing 2024年第3期7卷 358-382页

作者： Lujing Gao zixuan liu Daniel Dikovsky Jiqian Wang Deqing Mei Lihi Adler-Abramovich Ehud Gazit Kai Tao State Key Laboratory of Heavy Oil Processing and Centre for Bioengineering and Biotechnology College of Chemistry and Chemical EngineeringChina University of Petroleum(East China)Qingdao 266580China Future Science Research Institute Hangzhou Global Scientific and Technological Innovation CentreHangzhou 311200China Zhejiang-Israel Joint Laboratory of Self-Assembling Functional Materials Hangzhou 311200China Redefine Meat Ltd. Rehovot 7670110Israel State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310058China Key Laboratory of Advanced Manufacturing Technology of Zhejiang Province School of Mechanical EngineeringZhejiang UniversityHangzhou 310058China Department of Oral Biology The Maurice and Gabriela Goldschleger School of Dental MedicineFaculty of Medical&Health SciencesTel Aviv UniversityTel Aviv 6997801Israel The Center for Nanoscience and Nanotechnology Tel Aviv UniversityTel Aviv 6997801Israel Department of Materials Science and Engineering Iby and Aladar FleischmanTel Aviv UniversityTel Aviv 6997801Israel The Shmunis School of Biomedicine and Cancer Research George S.Wise Faculty of Life SciencesTel Aviv UniversityTel Aviv 6997801Israel

Three-dimensional(3D)printing has attracted increasing research interest as an emerging manufacturing technology for devel-oping sophisticated and exquisite architecture through hierarchical printing.It has also been employed in various advanced industrial areas.The development of intelligent biomedical engineering has raised the requirements for 3D printing,such as flexible manufacturing processes and technologies,biocompatible constituents,and alternative bioproducts.However,state-of-the-art 3D printing mainly involves inorganics or polymers and generally focuses on traditional industrial fields,thus severely limiting applications demanding biocompatibility and biodegradability.In this regard,peptide architectonics,which are self-assembled by programmed amino acid sequences that can be flexibly functionalized,have shown promising potential as bioinspired inks for 3D printing.Therefore,the combination of 3D printing and peptide self-assembly poten-tially opens up an alternative avenue of 3D bioprinting for diverse advanced applications.Israel,a small but innovative nation,has significantly contributed to 3D bioprinting in terms of scientific studies,marketization,and peptide architectonics,including modulations and applications,and ranks as a leading area in the 3D bioprinting field.This review summarizes the recent progress in 3D bioprinting in Israel,focusing on scientific studies on printable components,soft devices,and tissue engineering.This paper further delves into the manufacture of industrial products,such as artificial meats and bioinspired supramolecular architectures,and the mechanisms,physicochemical properties,and applications of peptide self-assembly.Undoubtedly,Israel contributes significantly to the field of 3D bioprinting and should thus be appropriately recognized.

关键词： Israel 3D bioprinting Biomanufacturing Peptide self-assembly Integration of industry,education and research

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Supramolecular Bonding Competition Enabled Nanostructure Evolution and Mechanical Reinforcement

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CCS Chemistry 2024年第1期6卷 157-164页

作者： Yuting Wang Peng Meng Aidan Brock Yanan Xu Hang Meng zixuan liu Kan Zhang John McMurtrie Jingsan Xu School of Chemistry and Physics and Centre for Materials Science Queensland University of TechnologyBrisbaneQueensland 4000 Central Analytical Research Facility Institute for Future EnvironmentsQueensland University of TechnologyBrisbaneQueensland 4000 State Key Laboratory of Superhard Materials Department of Materials Science and Key Laboratory of Automobile MaterialsMOEJilin UniversityChangchun 130012

In this work,competition between different supramolecular interactions is investigated based on a fibrous crystal composed of hydrogen-bonded cyanuric acid(CA)and amidinothiourea(ADT).Melamine(M)is found to prevail over ADT and bond to CA due to its stronger triple H-bonding affiliation,forming hollow microtubes assembled by oriented CAM crystalline arrays,as guided by the directionality of peripheral hydrogen bonds.Furthermore,competitive interaction between hydrogen bonding and ionic/covalent bonding is demonstrated by mixing Ag+ions with the CA-ADT fibers,where sulfur atoms are abstracted from ADT molecules to produce Ag_(2)S ligaments.The in situ-formed Ag_(2)S serves as a binding glue to generate CA-ADT/Ag_(2)S composites with significantly enhanced mechanical strength compared to the pristine CA-ADT fiber pellet.

关键词： supramolecular interaction hydrogen bonds chemical bond competition hollow crystal array organic-inorganic composite

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Pyrite Concretions in the Lower Cambrian Niutitang Formation,South China:Response to Hydrothermal Activity

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Journal of Earth Science 2023年第4期34卷 1053-1067页

作者： zixuan liu Detian Yan Xing Niu Key Laboratory of Tectonics and Petroleum Resources Ministry of EducationChina University of GeosciencesWuhan 430074China School of Geosciences Yangtze UniversityWuhan 434023China

The Early Cambrian Niutitang Formation is characterized by wide distribution of black shales on Yangtze Block,South China.Here we have reported the pyrite concretions in the bottom of the Niutitang Formation deposited in the slope-basin environment of Yangtze Block.The pyrite concretion was mainly composed of pyrite associated with hydrothermal minerals(barite,hyalophane,tetrahedrite),followed by quartz and organic matter.Trace elements Mo and U displayed significant enrichment(enrichment factors > 10),indicating the euxinic bottom water condition.Cu,Ni,and excess Ba concentrations were relatively high,denoting high primary productivity.In-situ sulfur isotope compositions of pyrite concretions δ34Spy) showed little variations(13.2‰–19.4‰) and small fractionations compared to coeval seawater δ34Sso4.Petrological and geochemical analyses indicated the pyrite concretions were formed in the sediment-water interface during the early diagenesis,with H2S diffusing from the euxinic water,and influenced by hydrothermal activity leading to the coexistence of barite,hyalophane,and tetrahedrite.These results imply euxinic bottom water featured by high primary productivity and increasing riverine flux of sulfate from chemical weathering during the Early Cambrian.

关键词： shale pyrites black shale pyrite concretion depositional environment.

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Geophysical and orbital environments of asteroid 4692192016 HO3

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Astrodynamics 2023年第1期7卷 31-50页

作者： Xiangyu Li Daniel J.Scheeres Dong Qiao zixuan liu School of Aerospace Engineering Beijing Institute of TechnologyBeijing 100081China Ann and H.J.Smead Aerospace Engineering Department University of Colorado Boulder429 UCBBoulderCO 80309USA

Asteroid 469219 Kamo'oalewa,also named 2016 HO3,is a small-size fast-rotating near-Earth asteroid,which is a potential target for future explorations.Owing to its weak gravity and fast spin rate,the dynamics on the surface or in the vicinity of 2016 HO3 are significantly different from those of planets or other small bodies explored in previous missions.In this study,the geophysical and orbital environments of 2016 HO3 were investigated to facilitate a potential mission design.First,the geormnetric and geopotential topographies of 2016 HO3 were examined using difterent shape models.The liftoff and escape conditions on its fast-rotating surface were investigated.Then,the periodic orbits around 2016 HO3 were studied in the asteroid-fixed frame and the Sun-asteroid frame considering the solar radiation pressure.The stable regions of the terminator orbits were discussed using different parameters.Finally,the influence of the nonspherical shape on the terminator orbits was examined.The precise terminator orbits around a real shape model of 2016 HO3 were obtained and verified in the high-fidelity model.This study shows that the polar region of 2016 HO3 is the primary region for landing or sampling,and the terminator orbits are well suited for global mapping and measurements of 2016 HO3.The analysis and methods can also serve as references for the exploration of other small fast-rotating bodies.

关键词： asteroid 2016 HO3 geophysical environment solar radiation pressure terminator orbit

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Effects of different processing methods on the lipid composition of hazelnut oil:a lipidomics analysis

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Food Science and Human Wellness 2022年第2期11卷 427-435页

作者： Jiayang Sun Xiaonuo Feng Chunmao Lyu Shuang Zhou zixuan liu College of Food Science Shenyang Agricultural UniversityShenyang 110866China College of Bioscience and Biotechnology Shenyang Agricultural UniversityShenyang 110866China

Although hazelnut oil is rich in nutrients,its quality is greatly affected by how it is processed.However,no studies to date have comprehensively analyzed the lipid composition of hazelnut oil using different processing methods.Here,we conducted a lipidomics analysis using UPLC-QTOF-MS to characterize the lipid composition of cold-pressed hazelnut oil(CPO),ultrasonic-assisted hexane hazelnut oil(UHO)and enzyme-assisted aqueous hazelnut oil(EAO).A total of 10 subclasses of 98 lipids were identified,including35 glycerolipids(GLs),56 glycerophospholipids(GPs)and 7 sphingolipids(SPs).The total lipid and GL content were the highest in CPO,GP content was the highest in UHO and the ceramide content in SPs was most abundant in EAO.Multivariate statistical analysis showed that the lipid profiles of hazelnut oil prepared with different processing methods varied.Twelve significantly different lipids(TAG 54:3,TAG 52:2,TAG54:4,TAG 54:2,TAG 52:3,TAG 54:5,DAG 36:2,DAG 36:4,DAG 36:3,PC 36:2,PA 36:2 and PE 36:3)were identified,and these lipids could potentially be used as biomarkers to distinguish between hazelnut oil subjected to different processing methods.Our results provide useful information for hazelnut oil applications and new insight into the effects of edible oil processing.

关键词： Lipidomics Hazelnut oil Processing method Lipid composition

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Regularity for 3-D MHD Equations in Lorentz Space L^(3,∞)

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Communications in Mathematical Research 2023年第1期39卷 107-135页

作者： Xiangao liu Yueli liu zixuan liu School of Mathematic Sciences Fudan UniversityShanghaiChina

.The regularity for 3-D MHD equations is considered in this paper,it is proved that the solutions(v,B,p)are Holder continuous if the velocity field v∈L^(∞)(0,T;L^(3,∞)_(x)(R^(3))with local small condition r^(-3)|{x... 详细信息

关键词： Lorentz space backward uniqueness MHD equations.

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油气工业中氢对双相不锈钢腐蚀行为的影响

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工程科学学报 2024年第4期46卷 684-694页

作者：刘子轩王竹唐德志金杰张雷北京科技大学新材料技术研究院北京100083 中国石油规划总院北京100083

随着双相不锈钢在海洋油气田和酸性服役工况下的应用越来越多,临氢环境下双相不锈钢的失效风险逐步提高.目前海洋油气田双相不锈钢管道面临的氢损伤失效主要出现在海水过阴极保护环境和含H2S的酸性服役环境.氢的引入除了引起双相不锈钢... 详细信息

随着双相不锈钢在海洋油气田和酸性服役工况下的应用越来越多,临氢环境下双相不锈钢的失效风险逐步提高.目前海洋油气田双相不锈钢管道面临的氢损伤失效主要出现在海水过阴极保护环境和含H2S的酸性服役环境.氢的引入除了引起双相不锈钢腐蚀性能和组织的改变外,还不可避免遭受氢损伤,包括氢脆、氢致开裂等.本文综述了氢进入双相不锈钢后引起的氢损伤问题、腐蚀性能的改变和组织的改变,旨在为双相不锈钢油气工业临氢环境下的应用提供指导;总结了氢在双相不锈钢中扩散和分布的研究现状:氢在双相不锈钢中的扩散路径是曲折的,倾向于在晶界处聚集,随后向铁素体扩散;介绍了与氢相关的现代分析技术与方法,同时展望了临氢环境双相不锈钢研究的发展趋势:氢损伤理论机制仍不完善,需要将现代分析技术和理论计算模拟相结合完善和发展新的氢损伤理论模型.

关键词：油气工业双相不锈钢临氢环境氢损伤腐蚀行为

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Research on the Value Positioning of University Library Based on Customer Delivered Value

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Asian Agricultural Research 2023年第2期15卷 64-67页

作者： zixuan liu Weimin YANG Beijing University of Agriculture Beijing 102206China

With the rise of various new reading media and the rapid development of the digitization of paper resources,the traditional function positioning of university libraries based on information query is facing unprecedented challenges.How to deal with the change of social information?The library should be demand-oriented,re-examine its own value and find a new starting point.With the help of the concept of customer delivered value and based on 4P theory,this paper constructs the value chain of university library from the dimensions of product,image,personnel and service,and forms a multi-dimensional development positioning system.

关键词： University Library Customer delivered value Positioning

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Insights into Pore Structure and Fractal Characteristics of the Lower Cambrian Niutitang Formation Shale on the Yangtze Platform,South China

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Journal of Earth Science 2020年第1期31卷 169-180页

作者： zixuan liu Detian Yan Xing Niu Key Laboratory of Tectonics and Petroleum Resources Ministry of EducationChina University of GeosciencesWuhan 430074China School of Earth Resources China University of GeosciencesWuhan 430074China Sedimentary Basin Research Center Yangtze UniversityWuhan 430074China

Shales from the Lower Cambrian Niutitang Formation of Yangtze Platform have been widely investigated due to its shale gas potential.To better illustrate the pore structure and fractal characteristics of shale,a series of experiments were conducted on outcrop samples from the Lower Cambrian Niutitang Formation on Yangtze Platform,including X-ray diffraction(XRD),field-emission scanning electron microscopy(FE-SEM) and low-temperature nitrogen adsorption.Frenkel-Halsey-Hill(FHH) model was adopted to calculate the fractal dimensions.Furthermore,the relationships between fractal dimensions and pore structure parameters and mineral composition are discussed.FE-SEM observation results show that interparticle pores are most developed in shale,followed by intraparticle pores.This study identified the fractal dimensions D1(ranging from 2.558 0 to 2.710 2) and D2(ranging from 2.541 5 to 2.765 2).The pore structure of the Niutitang Formation shale is primarily controlled by quartz and clay content.Fractal dimensions are able to characterize the pore structure complexity of Niutitang Formation shale because D1 and D2 correlate well with average pore diameter and quartz content.

关键词： Niutitang Formation Yangtze area shale pore structure fractal features

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Construction of Smart Library Based on the Agricultural Information from Metaverse Horizon

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Asian Agricultural Research 2023年第3期15卷 52-54,58页

作者： Weimin YANG zixuan liu Beijing University of Agriculture Beijing 102206China

Metaverse is a virtual world,but it is possible and even becomes a trend that metaverse interacts with the real world along with the sci-tech and social development.Smart library is a main direction of modern library development,from informatization to digitization and then intelligent-based,modernization of library has been improved qualitatively.Emergence of metaverse brings a brand-new horizon to the generation and application of agricultural information,this paper made primary explorations the requirements and action mechanism of agricultural information on the construction of smart library within the external constraint of metaverse.

关键词： Agricultural information Metaverse Smart library Dimension

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