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Room-temperature ferromagnetism and piezoelectricity in metalfree 2D semiconductor crystalline carbon nitride

Nano Research 2024年第6期17卷 5670-5679页

作者： Yong Wang Dingyi Yang Wei Xu Yongjie Xu Yu Zhang zixuan cheng Yizhang Wu Xuetao Gan Wei Zhong Yan Liu Genquan Han Yue Hao Wide Bandgap Semiconductor Technology Disciplines State Key Laboratory School of MicroelectronicsAcademy of Advanced Interdisciplinary ResearchXidian UniversityXi’an 710071China Emerging Device and Chip Laboratory Hangzhou Institute of TechnologyXidian UniversityHangzhou 311200China INRS Centre for Energy Materials and Telecommunications1650 Boul.Lionel BouletVarennesQC J3X 1P7Canada National Laboratory of Solid State Microstructures Collaborative Innovation Center of Advanced Microstructures and Jiangsu Provincial Key Laboratory for NanotechnologyNanjing UniversityNanjing 210093China School of Education Jiangsu Open UniversityNanjing 210036China Department of Physics Shaanxi University of Science and TechnologyXi’an 710021China Department of Applied Physical Sciences The University of North Carolina at Chapel HillChapel HillNC 27514USA Key Laboratory of Light Field Manipulation and Information Acquisition Ministry of Industry and Information Technologyand Shaanxi Key Laboratory of Optical Information TechnologySchool of Physical Science and TechnologyNorthwestern Polytechnical UniversityXi'an 710129 China

Two-dimensional(2D)materials that combine ferromagnetic,semiconductor,and piezoelectric properties hold significant potential for both fundamental research and spin electronic devices.However,the majority of reported 2D ferromagnetic-semiconductor-piezoelectric materials rely on d-electron systems,which limits their practical applications due to a Curie temperature lower than room temperature(RT).Here,we report a high-crystallinity carbon nitride(CCN)material based on sp-electrons using a chemical vapor deposition *** exhibits a band gap of 1.8 eV and has been confirmed to possess substantial in-plane and out-of-plane piezoelectricity.Moreover,we acquired clear evidences of ferromagnetic behavior at room temperature.Extensive structural characterizations combined with theoretical calculations reveal that incorporating structural oxygen into the highly ordered heptazine structure causes partial substitution of nitrogen sites,which is primarily responsible for generating room-temperature ferromagnetism and piezoelectricity.As a result,the strain in wrinkles can effectively modulate the domain behavior and piezoelectric potential at room temperature.The addition of RT ferromagnetic-semiconductor-piezoelectric material based on sp-electrons to the family of two-dimensional materials opens up numerous possibilities for novel applications in fundamental research and spin electronic devices.

关键词： crystallinity carbon nitride room-temperature ferromagnetism piezoelectricity magnetic force microscopy density functional theory(DFT)calculations

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Radiomics approach for preoperative identification of stages Ⅰ-Ⅱand Ⅲ-Ⅳ of esophageal cancer

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Chinese Journal of Cancer Research 2018年第4期30卷 396-405页

作者： Lei WU Cong Wang Xianzheng Tan zixuan cheng Ke Zhao Lifen Yan Yanli Liang Zaiyi Liu Changhong Liang School of Medicine South China University of Technology Guangzhou 510006 China Department of Radiology Guangdong General HospitalGuangdong Academy of Medical Sciences Guangzhou 510080 China School of Automation Science and Engineering South China University of Technology Guangzhou 510641 China

Objective： To predict preoperative staging using a radiomics approach based on computed tomography （CT）images of patients with esophageal squamous cell carcinoma （ESCC）.Methods： This retrospective study included 154 patients （primary cohort： n： t 14; validation cohort： n：40） withpathologically confirmed ESCC. All patients underwent a preoperative CT scan from the neck to abdomen. Highthroughput and quantitative radiomics features were extracted from the CT images for each patient. A radiomicssignature was constructed using the least absolute shrinkage and selection operator （Lasso）. Associations betweenradiomics signature, tumor volume and ESCC staging were explored. Diagnostic performance of radiomicsapproach and tumor volume for discriminating between stages Ⅰ-Ⅱand Ⅲ-Ⅳ was evaluated and compared usingthe receiver operating characteristics （ROC） curves and net reclassification improvement （NRI）.Results= A total of 9,790 radiomics features were extracted. Ten features were selected to build a radiomicssignature after feature dimension reduction. The radiomics signature was significantly associated with ESCCstaging （P〈0.001）, and yielded a better performance for discrimination of early and advanced stage ESCC comparedto tumor volume in both the primary [area under the receiver operating characteristic curve （AUC）： 0.795 vs. 0.694,P=0.003; NRI=0.424）] and validation cohorts （AUC： 0.762 vs. 0.624, P=0.035; NRI=0.834）.Conclusions： The quantitative approach has the potential to identify stage Ⅰ-Ⅱand Ⅲ-Ⅳ ESCC beforetreatment.

关键词： Esophageal cancer tumor staging diagnostic imaging tumor volume

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Computed tomography-based radiomics for prediction of neoadjuvant chemotherapy outcomes in locally advanced gastric cancer: A pilot study

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Chinese Journal of Cancer Research 2018年第4期30卷 406-414页

作者： Zhenhui Li Dafu Zhang Youguo Dai Jian Dong Lin Wu Yajun Li zixuan cheng Yingying Ding Zaiyi Liu Department of Radiology the Third Affiliated Hospital of Kunming Medical University Yunnan Cancer Hospital Department of Abdominal Surgery the Third Affiliated Hospital of Kunming Medical University Yunnan Cancer Hospital Department of Pathology the Third Affiliated Hospital of Kunming Medical University Yunnan Cancer Hospital Department of Radiology Guangdong General Hospital Guangdong Academy of Medical Sciences School of Medicine South China University of Technology

Objective： The standard treatment for patients with locally advanced gastric cancer has relied on perioperativeradio-chemotherapy or chemotherapy and surgery. The aim of this study was to investigate the wealth of radiomicsfor pre-treatment computed tomography （CT） in the prediction of the pathological response of locally advancedgastric cancer with preoperative chemotherapy.Methods： Thirty consecutive patients with CT-staged Ⅱ/Ⅲ gastric cancer receiving neoadjuvant chemotherapywere enrolled in this study between December 2014 and March 2017. All patients underwent upper abdominal CTduring the unenhanced, late arterial phase （AP） and portal venous phase （PP） before the administration ofneoadjuvant chemotherapy. In total, 19,985 radiomics features were extracted in the AP and PP for each patient.Four methods were adopted during feature selection and eight methods were used in the process of building theclassifier model. Thirty-two combinations of feature selection and classification methods were examined. Receiveroperating characteristic （ROC） curves were used to evaluate the capability of each combination of feature selectionand classification method to predict a non-good response （non-GR） based on tumor regression grade （TRG）.Results： The mean area under the curve （AUC） ranged from 0.194 to 0.621 in the AP, and from 0.455 to 0.722in the PP, according to different combinations of feature selection and the classification methods. There was onlyone cross-combination machine-learning method indicating a relatively higher AUC （〉0.600） in the AP, while 12cross-combination machine-learning methods presented relatively higher AUCs （all 〉0.600） in the PP. The featureselection method adopted by a filter based on linear discriminant analysis ＋ classifier of random forest achieved asignificantly prognostic performance in the PP （AUC, 0.722~0.108; accuracy, 0.793; sensitivity, 0.636; specificity,0.889; Z=2.039; P=0.041）.Conclusions： It is possible to predict non-GR after neoadiuvant chemotherapy in locally advanced gastricca

关键词： Gastric cancer neoadjuvant chemotherapy radiomics tomography spiral computed

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A CT-based radiomics nomogram for prediction of human epidermal growth factor receptor 2 status in patients with gastric cancer

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Chinese Journal of Cancer Research 2020年第1期32卷 62-71页

作者： Yexing Li zixuan cheng Olivier Gevaert Lan He Yanqi Huang Xin Chen Xiaomei Huang Xiaomei Wu Wen Zhang Mengyi Dong Jia Huang Yucun Huang Ting Xia Changhong Liang Zaiyi Liu Department of Radiology Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou 510080China Graduate College Shantou University Medical CollegeShantou 515041China School of Medicine South China University of TechnologyGuangzhou 510006China Stanford Center for Biomedical Informatics Research Department of Medicineand Department of Biomedical Data ScienceStanford UniversityCalifornia 94305USA Graduate College Southern Medical UniversityGuangzhou 510515China Department of Radiology Guangzhou First People’s HospitalGuangzhou 510180China Department of Radiology Zhuhai Hospital of Traditional Chinese and Western MedicineZhuhai 519000China Department of Radiology The Fifth People’s Hospital of ZhuhaiZhuhai 519055China

Objective: To develop and validate a computed tomography(CT)-based radiomics nomogram for predicting human epidermal growth factor receptor 2(HER2) status in patients with gastric cancer.Methods: This retrospective study included 134 patients with gastric cancer(HER2-negative: n=87;HER2-positive: n=47) from April 2013 to March 2018, who were then randomly divided into training(n=94) and validation(n=40) cohorts. Radiomics features were obtained from the CT images showing gastric cancer. Least absolute shrinkage and selection operator(LASSO) regression analysis was utilized for building the radiomics signature. A multivariable logistic regression method was applied to develop a prediction model incorporating the radiomics signature and independent clinicopathologic risk predictors, which were then visualized as a radiomics nomogram. The predictive performance of the nomogram was assessed in the training and validation cohorts.Results: The radiomics signature was significantly associated with HER2 status in both training(P<0.001) and validation(P=0.023) cohorts. The prediction model that incorporated the radiomics signature and carcinoembryonic antigen(CEA) level demonstrated good discriminative performance for HER2 status prediction,with an area under the curve(AUC) of 0.799 [95% confidence interval(95% CI): 0.704-0.894] in the training cohort and 0.771(95% CI: 0.607-0.934) in the validation cohort. The calibration curve of the radiomics nomogram also showed good calibration. Decision curve analysis showed that the radiomics nomogram was useful.Conclusions: We built and validated a radiomics nomogram with good performance for HER2 status prediction in gastric cancer. This radiomics nomogram could serve as a non-invasive tool to predict HER2 status and guide clinical treatment.

关键词： Gastric cancer human epidermal growth factor receptor 2 radiomics X ray computed tomography

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人工智能与虚拟现实技术在汉服产业中的价值初探

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西部皮革 2024年第9期46卷 34-36页

作者：丁宇诚冯艺淞吴雨航李浩龙雨程子萱颜璐四川传媒学院浙江理工大学

人工智能在汉服产业中的应用，可有效提升生产效率和设计创新能力，通过数据分析和算法优化，实现精准市场需求预测和生产流程优化。同时，虚拟现实技术为汉服产业带来了全新的消费者体验和销售模式，通过虚拟试穿等方式，增强消费者的... 详细信息

人工智能在汉服产业中的应用，可有效提升生产效率和设计创新能力，通过数据分析和算法优化，实现精准市场需求预测和生产流程优化。同时，虚拟现实技术为汉服产业带来了全新的消费者体验和销售模式，通过虚拟试穿等方式，增强消费者的购买意愿和品牌认同感。此外，人工智能与虚拟现实的融合应用，为汉服产业提供了更精准的市场分析和营销策略，助力产业创新发展，推动产业迈向更加智能化、品牌化的新阶段。

关键词：人工智能虚拟现实汉服

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An Interactive Collaborative Creation System for Shadow Puppets Based on Smooth Generative Adversarial Networks

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Computers, Materials & Continua 2024年第6期79卷 4107-4126页

作者： cheng Yang Miaojia Lou Xiaoyu Chen zixuan Ren Department of Industrial Design Hangzhou City UniversityHangzhou310000China College of Computer Science and Technology Zhejiang UniversityHangzhou310000China

Chinese shadow puppetry has been recognized as a world intangible cultural heritage.However,it faces substantial challenges in its preservation and advancement due to the intricate and labor-intensive nature of crafting shadow puppets.To ensure the inheritance and development of this cultural heritage,it is imperative to enable traditional art to flourish in the digital era.This paper presents an Interactive Collaborative Creation System for shadow puppets,designed to facilitate the creation of high-quality shadow puppet images with greater ease.The system comprises four key functions:Image contour extraction,intelligent reference recommendation,generation network,and color adjustment,all aimed at assisting users in various aspects of the creative process,including drawing,inspiration,and content generation.Additionally,we propose an enhanced algorithm called Smooth Generative Adversarial Networks(SmoothGAN),which exhibits more stable gradient training and a greater capacity for generating high-resolution shadow puppet images.Furthermore,we have built a new dataset comprising high-quality shadow puppet images to train the shadow puppet generation model.Both qualitative and quantitative experimental results demonstrate that SmoothGAN significantly improves the quality of image generation,while our system efficiently assists users in creating high-quality shadow puppet images,with a SUS scale score of 84.4.This study provides a valuable theoretical and practical reference for the digital creation of shadow puppet art.

关键词： Shadow puppets deep learning image generation co-create

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Effects of Dietary Changes on the Gut Microbiota of Cynops orientalis

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Asian Herpetological Research 2024年第2期15卷 63-72页

作者： Yuting WANG Yuning XIE Siyu WU Wenwen ZHANG Xiner cheng zixuan LI Fangfei HAN Jiayi SHI Yingying SHI Zhirong HE Chunna ZHANG Yixin JIANG Na ZHAO Jiaqi LI Supen WANG College of Life Sciences Anhui Normal UniversityWuhu 241000AnhuiChina Nanjing Institute of Environmental Sciences Ministry of Ecology and Environment of ChinaNanjing 210042JiangsuChina School of Ecology and Environment Anhui Normal UniversityWuhu 241002AnhuiChina Key Laboratory of Zoological Systematics and Evolution Institute of ZoologyChinese Academy of SciencesBeijing 100101China

The gut microbiota plays a pivotal role in the maintenance of health for amphibians,and it has been fully recognized,but the effectiveness of various influencing factors has not yet been fully clarified.Although this association should be considered while the amphibian order Caudata is facing a severe situation of population decline and extinction,there is little understanding of the association between diets and the diversity of gut microbiota in the amphibian order Caudata.Here,we conducted an extensive analysis of the gut microbiota of Cynops orientalis fed different diets using functional prediction and 16S rRNA amplicon sequencing techniques.First,we found that wild individuals had greater gut microbial diversity and richness in comparison to captive individuals.Second,we identified the bacterial taxa associated with diets and observed differences in the relative abundance of gut microbiota among people on various diets.Finally,we have a predictive comprehension of the selection and adaptative significance of shared core ASVs in the gut microbiota in maintaining the healthy survival of C.orientalis in a large-scale spatiotemporal map.Our study emphasizes how diets alter the gut microbiota of Caudata and offers fresh perspectives on the conservation and captive management of species in Caudata.

关键词： 16S rRNA Caudata core microbiota diet gut microbiota

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C-DRG收付费政策实施对三明市公立医院住院费用及效率的影响研究

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中国医院管理 2023年第4期43卷 29-33页

作者：程子瑄阮娴静广东药科大学医药商学院广东广州510006

目的分析《全国按疾病诊断相关分组收付费规范》(C-DRG)收付费改革对三明市县级及以上公立医院医疗服务效率和住院费用等的影响。方法对三明市县级及以上公立医院2016年1月—2021年12月的医疗运行情况报表进行整理与分析,采用间断时间... 详细信息

目的分析《全国按疾病诊断相关分组收付费规范》(C-DRG)收付费改革对三明市县级及以上公立医院医疗服务效率和住院费用等的影响。方法对三明市县级及以上公立医院2016年1月—2021年12月的医疗运行情况报表进行整理与分析,采用间断时间序列分析改革前后各指标趋势的变化。结果与改革前相比,C-DRG收付费政策实施后,出院者平均住院天数增长速度放缓,床位使用率逐渐降低(P<0.05),每床日平均费用缓慢增长(P<0.05),出院患者平均费用呈上升趋势,出院者药品费用占比缓慢增长(P<0.05),检验检查费用占比每月降低放缓(P<0.05),医疗服务费用占比有所下降(P<0.05)。结论C-DRG收付费改革政策的实施对公立医院医疗服务效率的提升有一定的积极作用,但对次均费用影响不大,费用结构有待优化。

关键词：全国按疾病诊断相关分组收付费规范住院费用中断时间序列三明市

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财政资源统筹与部门绩效计划制度建构:美国部门整体预算绩效计划制度的实践与镜鉴

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中国行政管理 2023年第12期39卷 44-53页

作者：马海涛曹堂哲程子轩中央财经大学中央财经大学政府管理学院北京100081

强化财政资源统筹,提高预算绩效管理的系统性、整体性和协同性是深化预算管理制度改革的要求。绩效计划是美国至今推行的联邦绩效管理的关键环节,也是实现战略与预算衔接的重要机制。经过多年的改革与探索,美国现已形成一套较为完善的... 详细信息

强化财政资源统筹,提高预算绩效管理的系统性、整体性和协同性是深化预算管理制度改革的要求。绩效计划是美国至今推行的联邦绩效管理的关键环节,也是实现战略与预算衔接的重要机制。经过多年的改革与探索,美国现已形成一套较为完善的绩效计划工作机制。文章以美国绩效预算改革的历史脉络为逻辑起点,深入分析其所推行的绩效计划制度的基本框架、内容要素和主要挑战。最后,立足我国实际,提出深化我国部门预算绩效管理改革的有益启示,包括建立部门绩效计划制度,明确绩效计划与预算时限,增强绩效目标的系统性,实现业财融合,加强绩效信息公开等。

关键词：绩效计划绩效管理绩效预算绩效目标

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“锚定结”法小鼠颈部异位心脏移植模型构建及其稳定性测试

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陆军军医大学学报 2024年第8期46卷 822-828页

作者：李子炫方易冰程伟陆军军医大学(第三军医大学)第一附属医院心脏外科重庆400038

目的在传统Cuff法(“袖套”法)血管吻合技术基础上进行改良,优化小鼠颈部异位心脏移植操作步骤、过程,以建立更稳定的小鼠颈部异位心脏移植模型。方法将6~8周龄雄性C57BL/6小鼠(体质量20~24 g)分为实验组(通过“锚定结”法进行小鼠颈部... 详细信息

目的在传统Cuff法(“袖套”法)血管吻合技术基础上进行改良,优化小鼠颈部异位心脏移植操作步骤、过程,以建立更稳定的小鼠颈部异位心脏移植模型。方法将6~8周龄雄性C57BL/6小鼠(体质量20~24 g)分为实验组(通过“锚定结”法进行小鼠颈部异位心脏移植)和对照组(用传统Cuff法进行小鼠颈部异位心脏移植)。记录各项操作步骤时间、血管外翻次数、血管修剪次数、实验失败原因等。术后每天观察、触摸判断小鼠颈部供心存活情况,存活>48 h为移植成功。术后第7、14天HE染色观察实验组小鼠吻合血管处组织;第7天心肌肌钙蛋白T(cardiac troponin T,cTnT)染色观察2组小鼠供心。结果①实验组共进行25只移植,失败2只,供心存活率92%;对照组共进行25只移植,失败8只,供心存活率68%。实验组动脉平均外翻1.16次,修剪0.04次;静脉平均外翻1.16次,修剪0.04次。对照组动脉平均外翻2.00次,修剪0.21次;静脉平均外翻2.28次,修剪0.46次。②实验组、对照组的颈部心脏移植总时间[(77.22±3.82)vs(87.49±8.01)min]、分离血管+套管时间[(30.06±2.68)vs(36.50±6.67)min]、颈部血管吻合时间[(7.31±1.08)vs(12.34±2.58)min]差异有统计学意义(P<0.05)。③术后第7、14天实验组吻合血管处组织HE染色显示血管通畅。④术后第7天供心cTnT染色情况提示对照组、实验组均无大面积坏死。结论“锚定结”法进行小鼠颈部异位心脏移植保证了单人显微操作的稳定、高效,术后供心存活时间长、吻合血管通畅率高、心功能状态好、术后并发症少。

关键词：心脏移植袖套法小鼠模型

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