检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

氯氧镁水泥结构胶研制及界面高温性能研究

河北工业大学学报 2024年第4期53卷 76-84页

作者：郭蓉王琴赵少伟任梓炜河北工业大学土木与交通学院天津300401

首先对氯氧镁水泥的配比进行优化设计,通过考察改性氯氧镁水泥的力学性能、耐水性能和耐高温性能,辅助微观测试手段进行分析,从而确定氯氧镁水泥的最优配比,结果显示:当采用MgO/MgCl_(2)/H_(2)O摩尔比为9∶1∶10.9,氯氧镁水泥胶的力学... 详细信息

首先对氯氧镁水泥的配比进行优化设计,通过考察改性氯氧镁水泥的力学性能、耐水性能和耐高温性能,辅助微观测试手段进行分析,从而确定氯氧镁水泥的最优配比,结果显示:当采用MgO/MgCl_(2)/H_(2)O摩尔比为9∶1∶10.9,氯氧镁水泥胶的力学性能最优;当羟基乙酸掺量为2%时,软化系数提高到0.88,明显改善氯氧镁水泥的耐水性能,能够满足加固工程需要;加入2%的硼酸镁晶须能够有效降低体积收缩率,提高抗压强度;然后对25~500℃高温处理后的氯氧镁水泥作为胶黏剂的界面黏结性能进行单面剪切试验,结果表明:25℃下氯氧镁水泥胶的界面黏结强度比环氧树脂为胶黏剂低10%,当温度升高至200℃时,界面黏结强度仍为25℃下的84.06%,300℃黏结强度下降为25℃的68.20%。

关键词：高温氯氧镁水泥胶黏剂 CFRP-混凝土界面单面剪切

Ultrasound cascade regulation of nano-oxygen hybrids triggering ferroptosis augmented sonodynamic anticancer therapy

在线全文

学校读者我要写书评

暂无评论

Nano Research 2023年第5期16卷 7280-7292页

作者： Yue Sun Yihui Wang Ruyin Han ziwei ren Xin Chen Wenzhuo Dong Stephen Choi Quanhong Liu Xiaobing Wang Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest ChinaCollege of Life SciencesShaanxi Normal UniversityXi’an 710119China Department of Ultrasound Medicine Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430000China Kerry Rehabilitation Medicine Research Institute Shenzhen 518000China

Sonodynamic therapy(SDT)has attracted great interest in the field of cancer therapy because of its non-invasiveness,deep penetration,spatiotemporal ***,the sonodynamic effect is severely hindered by hypoxia and a high glutathione(GSH)level in tumor *** this work,a new type of nanohybrid sonosensitizer is designed,which incorporates several prominent advantages of organic,inorganic,natural sonosensitizers for imaging-guided SDT and ferroptosis *** an endogenous transporter,hemoglobin(Hb)has dual functions of oxygen and iron ***,Hb can transport iron to the tumor site for Fe-dependent ferroptosis,yet this oxygen carrier is able to enhance the sensitivity of tumor cells to oxygen-driven *** innovatively hybridized Hb,sinoporphyrin sodium(DVDMS),titanium dioxide(TiO_(2))to prepare an integrated nano-oxygen carrier(designated as HDT)for multifarious cancer theranostics,which not only attained satisfactory sonosensitization of DVDMS/TiO_(2)but also achieved oxygen-boosted SDT and potent ferroptosis via *** ultrasound irradiation,the oxygenation of HDT markedly amplified the generation of reactive oxygen species(ROS)in hypoxic tumors,promoted the valence transition of Hb to accelerate Fenton reaction,led to *** strategy virtually eradicated tumors in situ and exhibited immunoregulatory potential for augmenting anti-tumor effects in vivo and in vitro through ROS formation,O_(2)self-supplement,GSH depletion,lipid ***,HDT demonstrated excellent dual-modal imaging performance,providing a valuable platform for photoacoustic/fluorescence-guided SDT and ferroptosis induction in tumor cells.

关键词： sonodynamic therapy nano-oxygen carrier sono-Fenton ferroptosis hypoxic tumor environment

Dissolved organic matter accelerates microbial degradation of 17 alpha-ethinylestradiol in the presence of iron mineral

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第5期139卷 364-376页

作者： Huan He Min Shi Xiaoxia Yang Juhong Zhan Yanting Lin ziwei Guo Zhicheng Liao Chaochao Lai Xiaomin ren Bin Huang Xuejun Pan Faculty of Environmental Science and Engineering Kunming University of Science and TechnologyKunming 650500China Yunnan Provincial Key Lab of Soil Carbon Sequestration and Pollution Control Kunming 650500China Research Institute for Environmental Innovation(Suzhou)Tsinghua Suzhou 215163China

Dissolved organic matter(DOM)and iron minerals widely existing in the natural aquatic environment can mediate the migration and transformation of organic ***,the mechanism of interaction between DOM and iron minerals in the microbial degradation of pollutants deserves further *** this study,the mechanism of 17 alphaethinylestradiol(EE2)biodegradation mediated by humic acid(HA)and three kinds of iron minerals(goethite,magnetite,and pyrite)was *** results found that HA and iron minerals significantly accelerated the biodegradation process of EE2,and the highest degradation efficiency of EE2(48%)was observed in the HA-mediated microbial system with pyrite under aerobic ***,it had been demonstrated that hydroxyl radicals(HO·)was the main active substance responsible for the microbial degradation of ***·is primarily generated through the reaction between hydrogen peroxide secreted by microorganisms and Fe(II),with aerobic conditions being more *** presence of iron minerals and HA could change the microbial communities in the EE2 biodegradation *** findings provide new information for exploring the migration and transformation of pollutants by microorganisms in iron-rich environments.

关键词： Dissolved organic matter Iron mineral 17 alpha-ethinylestradiol Biodegradation

Transcriptomic analysis reveals hub genes and pathways in response to acetic acid stress in Kluyveromyces marxianus during high-temperature ethanol fermentation

在线全文

学校读者我要写书评

暂无评论

Stress Biology 2023年第1期3卷 288-299页

作者： Yumeng Li Shiqi Hou ziwei ren Shaojie Fu Sunhaoyu Wang Mingpeng Chen Yan Dang Hongshen Li Shizhong Li Pengsong Li Beijing Key Lab for Source Control Technology of Water Pollution College of Environmental Science and EngineeringBeijing Forestry UniversityBeijing 100083China Engineering Research Center for Water Pollution Source Control&Eco-Remediation College of Environmental Science and EngineeringBeijing Forestry UniversityBeijing 100083China Institute of New Energy Technology Tsinghua UniversityBeijing 100084China

The thermotolerant yeast Kluyveromyces marxianus is known for its potential in high-temperature ethanol fermentation,yet it suffers from excess acetic acid production at elevated temperatures,which hinders ethanol *** better understand how the yeast responds to acetic acid stress during high-temperature ethanol fermentation,this study investigated its transcriptomic changes under this *** sequencing(RNA-seq)was used to identify differentially expressed genes(DEGs)and enriched gene ontology(GO)terms and pathways under acetic acid *** results showed that 611 genes were differentially expressed,and GO and pathway enrichment analysis revealed that acetic acid stress promoted protein catabolism but repressed protein synthesis during high-temperature ***-protein interaction(PPI)networks were also constructed based on the interactions between proteins coded by the *** genes and key modules in the PPI networks were identified,providing insight into the mechanisms of this yeast’s response to acetic acid *** findings suggest that the decrease in ethanol production is caused by the imbalance between protein catabolism and protein ***,this study provides valuable insights into the mechanisms of ***’s response to acetic acid stress and highlights the importance of maintaining a proper balance between protein catabolism and protein synthesis for high-temperature ethanol fermentation.

关键词： Kluyveromyces marxianus Acetic acid Transcriptomics Protein-protein interaction network

Clinical study on eye metastasis in patients with breast cancer

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2014年第5期127卷 961-967页

作者： Ji Guangyan Xing Lei Huang Jianbo Kong Lingquan Wang ziwei ren Guosheng Wu Kainan Department of General Surgery First Affiliated Hospital of Chongqing Medical University Chongqing 400016 China

Metastasis is one of the most common manifestations of *** the treatment options and life expectancy of the cancer patients are improving,the numbers of different metastatic lesions,including those uncommon metastatic sites are expected to *** metastasis from carcinoma,which is the most common type of ocular malignancy in adults,is found in an increasing number of patients,mostly with breast and lung cancer.

关键词： breast cancer choroidal metastasis treatment eyes examination

Surgical timing and long-term outcomes in patients with severe haemorrhagic spinal cord cavernous malformations

在线全文

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2024年第4期9卷 439-445页

作者： An Tian ziwei Cui Jian ren Yeqing ren Ming Ye Guilin Li Chuan He Xiaoyu Li Gao Zeng Peng Hu Yongjie Ma Jiaxing Yu Jingwei Li Lisong Bian Fan Yang Qianwen Li Feng Ling Tao Hong Liyong Sun Hongqi Zhang Department of Neurosurgery Xuanwu Hospital Capital Medical UniversityBeijingChina Department of Neurosurgery Beijing Haidian HospitalBeijingChina Department of Neurosurgery United Family HealthcareBeijingChina Department of Radiology Xuanwu Hospital Capital Medical UniversityBeijingChina

Background Surgical resection of the lesions remains the main treatment method for most symptomatic spinal cord cavernous malformations(SCCMs)to eliminate the occupation and associated subsequent lifelong haemorrhagic ***,the timing of surgical intervention remains controversial,especially for patients in the acute stage after severe *** Patients diagnosed with SCCMs who were surgically treated between January 2002 and December 2021 were selected and retrospectively *** Modified McCormick Scale(MMS)was used to evaluate neurological and disability *** medical information was reviewed,and all patients were followed up for at least 6 *** A total of 279 patients were ultimately *** regard to long-term outcomes,110(39.4%)patients improved,159(57.0%)remained unchanged and 10(3.6%)*** patients with an MMS score of 2–5 on admission,in univariate and multivariate analyses,a≤6 weeks period between onset and surgery(adjusted OR 3.211,95%CI 1.504 to 6.856,p=0.003)was a significant predictor of improved *** 69 patients who first presented with severe haemorrhage,undergoing surgery within 6 weeks of the onset of severe haemorrhage(adjusted OR 4.901,95%CI 1.126 to 21.325,p=0.034)was significantly associated with improvement of MMS *** Surgical timing can influence the long-term outcome of *** patients with symptomatic SCCMs,especially those with severe haemorrhage,early surgical intervention within 6 weeks can provide more benefit.

关键词： patients Surgical haemorrhagic

数字化时代的营销沟通:网络广告、网络口碑与手机游戏销量

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

南开管理评论 2018年第2期21卷 28-42页

作者：龚诗阳李倩赵平任紫微对外经济贸易大学国际商学院北京外国语大学国际商学院清华大学经济管理学院

在数字化时代,网络广告和网络口碑是企业最常采用的两种营销沟通工具。本文从整合营销沟通视角,探讨网络广告、网络口碑和数字化产品销量三者之间的相互影响关系,以及这些影响关系在产品生命周期中的动态发展变化。我们基于人人游戏公... 详细信息

在数字化时代,网络广告和网络口碑是企业最常采用的两种营销沟通工具。本文从整合营销沟通视角,探讨网络广告、网络口碑和数字化产品销量三者之间的相互影响关系,以及这些影响关系在产品生命周期中的动态发展变化。我们基于人人游戏公司提供的2012—2014年上市发行的5款手机游戏数据,围绕两个方面的内容开展研究:其一是网络广告如何动态影响网络口碑;其二是网络广告和网络口碑如何动态影响手机游戏销量。实证结果表明:(1)网络广告对网络口碑的数量、效价和差异均有显著的正向影响。在产品生命周期中,网络广告对口碑数量和口碑差异的影响逐渐减弱,而对口碑效价的影响逐渐增强。(2)网络广告和网络口碑的数量和效价均对游戏销量有显著的正向影响。在产品生命周期中,网络口碑和网络广告对游戏销量的影响呈现"此消彼长"的动态互补形态:在引入期和衰退期,网络广告对游戏销量的影响较强,而网络口碑对游戏销量的影响较弱;在成熟期,网络广告对游戏销量的影响较弱,而口碑对游戏销量的影响较强。基于研究结论,我们对如何优化网络广告和网络口碑的投入策略提供了详细的建议。

关键词：网络口碑网络广告产品销量手机游戏实证研究

一种带攻击角度约束的快速收敛无抖振制导律设计

在线全文

学校读者我要写书评

暂无评论

弹箭与制导学报 2018年第1期38卷 97-100,104页

作者：吕梅柏高环任子薇西北工业大学宇航学院西安710072 航天飞行动力学技术重点实验室西安710072 海军驻20所军事代表室西安710068 西安现代控制技术研究所西安710065

针对小型战术导弹以一定角度攻击目标的问题,文中提出了一种基于观测器的有限时间收敛制导律。利用非齐次干扰观测器对系统未知扰动进行估计,避免了制导律可能带来的抖振问题,采用幂次自适应趋近律,使得视线角及视线角速度在该制导律下... 详细信息

针对小型战术导弹以一定角度攻击目标的问题,文中提出了一种基于观测器的有限时间收敛制导律。利用非齐次干扰观测器对系统未知扰动进行估计,避免了制导律可能带来的抖振问题,采用幂次自适应趋近律,使得视线角及视线角速度在该制导律下能够快速的收敛至期望值,同时满足脱靶量和攻击角度约束要求,相比于传统制导律,具有一定的优越性。数值仿真结果表明了该方法的有效性。

关键词：攻击角度约束滑模制导有限时间收敛观测器

在线全文

学校读者我要写书评

暂无评论

半梦半醒之间--《铃芽之旅》叙事机制分析

当代动画 2023年第2期 28-32页

作者：洪帆任紫薇北京电影学院文学系北京电影学院中国电影编剧研究院

在《铃芽之旅》中,新海诚以“3·11日本大地震”为现实背景,筑造了主人公铃芽的“冒险之梦”。它以故事催眠手法对罹患集体创伤的民众进行心理治疗;同时,建构了摇摆在恋爱还是不恋爱之间的爱情主题情节线,以及同样摇摆于英雄事业还是个... 详细信息

在《铃芽之旅》中,新海诚以“3·11日本大地震”为现实背景,筑造了主人公铃芽的“冒险之梦”。它以故事催眠手法对罹患集体创伤的民众进行心理治疗;同时,建构了摇摆在恋爱还是不恋爱之间的爱情主题情节线,以及同样摇摆于英雄事业还是个人爱情之间的成长主题情节线。本文试图分析这场混合了分裂主题、多层级记忆与幻想的人造梦背后的叙事机制。

关键词：新海诚《铃芽之旅》造梦叙事机制后现代资料库