检索结果-南通市图书馆

Topica. Thera.y of a.ute Cuta.eous Leishma.ia.is Using Zinc Sulpha.e Solution 25% versus Podophyllin Solution 25%

Journa. of Cosmetics, Derma.ologica. Sciences a.d a.plica.ions 2017年第3期7卷 258-274页

作者： Kha.ifa.E. Sha.quie a.il a. Noa.mi zinah a. a. sharara Ba.a. a. Sa.eh Wa.na. S. a.-Sa.a. Depa.tment of Derma.ology College of Medicine University of Baghdad Iraqi & Arab Board for Dermatology & Venereology Baghdad Teaching Hospital Medical City College of Medicine Baghdad Iraq

Ba.kground: Zinc sulpha.e a. intra.esiona. a.d ora. thera.y wa. used a. a.successful thera.y in trea.ment of cuta.eous leishma.ia.is while 25% topica. podophyllin is now commonly used in the trea.ment of cuta.eous leishma.ia.is. Objective: To trea. a.ute cuta.eous leishma.ia.is using topica. zinc sulpha.e solution 25% to be compa.ed with topica. podophyllin solution 25%. Pa.ients a.d Methods: This is a.single, blind, interventiona., compa.a.ive study done in the Depa.tment of Derma.ology, Ba.hda. Tea.hing Hospita., Ba.hda., Ira. during the period from Ja.ua.y 2015 to June 2015. Forty pa.ients with a.tota. 88 lesions of a.ute cuta.eous leishma.ia.is were enrolled in this study;54 (61.36%) were dry lesions a.d 34 (38.6%) were ulcera.ive type. The dura.ion of lesions ra.ged from 2 - 11 (7.7 + 2.483) weeks. The size of the lesions ra.ged from 0.3 to 8 (2.13 ± 1.53) cm. There were 21 fema.es a.d 19 ma.es, fema.e to ma.e ra.io (1.1:1) a.d their a.es ra.ged from 1 to 60 (25.92 ± 16.59) yea.s. Dia.nosis wa. confirmed by tissue smea. a.d histopa.hology. Lesions were divided into two groups with ma.ching types a.d sizes, a.d ??scored a.cording to Sha.quie modified Leishma.ia.score to a.sess the objective response to the topica. or systemic thera.y a.d then during follow up responses were gra.ed into mild, modera.e, ma.ked response a.d complete clea.a.ce. Group a.trea.ed with topica. 25% podophyllin solution once weekly for a.ma.imum of 6 weeks, while group B wa. trea.ed with topica. 25% zinc sulpha.e solution twice da.ly for 6 weeks. Follow up wa. every 2 weeks during thera.y, a.d once monthly for 3 months a.ter thera.y. Results: a.tota. of 40 pa.ients with clinica. dia.nosis of a.ute cuta.eous leishma.ia.is were included in this study, with a.tota. of 88 lesions. Fifteen (37.50%) pa.ients ha. single lesion a.d 25 (62.50%) pa.ients ha. multiple lesions. Fa.ily history of CL wa. positive in 42.5% of pa.ients. a. the end of six weeks a.ter sta.ting thera.y, the tota. cure ra.e

关键词： Cuta.eous Leishma.ia.is Topica. Zinc Sulpha.e Topica. Podophyllin Sha.quie’s Modified Leishma.ia Score

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Topica. 40% <i>Lora.thus europa.us</i>Ointment a. a. a.terna.ive Medicine in the Trea.ment of a.ute Cuta.eous Leishma.ia.is versus Topica. 25% Podophyllin Solution

引用

Journa. of Cosmetics, Derma.ologica. Sciences a.d a.plica.ions 2017年第2期7卷 148-163页

作者： Kha.ifa.E. Sha.quie a.il a. Noa.mi Ba.a. M. Sa.eh zinah a. sharara Wa.na. S. a.-Sa.a. Depa.tment of Derma.ology College of Medicine University of Baghdad Iraqi & Arab Board for Dermatology & Venereology Baghdad Teaching Hospital Medical City College of Medicine Baghdad Iraq

Ba.kground: Cuta.eous leishma.ia.is (CL) is a. endemic disea.e in Ira., now is running in a. outbrea.s. Ma.y thera.ies ha.e been tried in trea.ment of the disea.e. Objective: Lora.thus europa.us (LE) is a.well-known medica. pla.t a.d ha. ma.y pha.ma.ologica. effects in ma.y in vitro studies. The a.m of the study is to eva.ua.e the effectiveness of 40% LE ointment a.d compa.ed it with topica. 25% podophyllin solution in trea.ment of a.ute CL. Pa.ients a.d Methods: Thirty five pa.ients with a.ute CL were enrolled in this single blinded, thera.eutic, compa.a.ive study, which wa. done in the Depa.tment of Derma.ology, Ba.hda. Tea.hing Hospita., Ba.hda., Ira. during Ja.ua.y 2015-Jully 2015. The tota. number of lesions were 86 (76 lesions trea.ed a.d ten lesions in a.covered a.ea.left without trea.ment a. control). Dura.ion of lesions ra.ged from 4 to 12 (7.37 ± 2.77) weeks. The size of lesions ra.ged from 0.5 - 7 (2.81 ± 1.76) cm. Dia.nosis wa. confirmed by biopsy a.d/or smea.s. Lesions were divided in to two groups a.d scored a. (mild, modera.e, ma.ked, complete cure) a.cording to a.modified Sha.quie’s leishma.ia.score to a.sess the objective response to the topica. or systemic thera.y. Group a.Thirty three (43.42%) lesions trea.ed with topica. 25% podophyllin solution once weekly for ma.imum 6 weeks. Group B: Forty three (56.58%) lesions trea.ed with 40% LE ointment once da.ly a. bedtime for 6 hours under occlusion for ma.imum 6 weeks. The followed-up wa. ca.ried out every 2 weeks for 8 weeks during trea.ment, then monthly for next three months a.ter end of thera.y. Results: the tota. number of lesions wa. 86 lesions, 46 (53.49%) were ulcera.ed a.d 40 (46.51%) were dry;18 (51.43%) pa.ients ha. single lesion while 17 (48.57%) pa.ients ha. multiple lesions. a. the end of thera.y (6 weeks a.ter sta.ting trea.ment), the cure ra.e wa. 84.84% in Group a. a.d 79.07% in Group B. When the two groups compa.ed with ea.h other there wa. no sta.istica. significa.ce difference were

关键词： Cuta.eous Leishma.a.is a.terna.ive Thera.y Lora.thus europa.us

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：