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Selective hydrocracking of light cycle oil into high-octane gasoline over bi-functional catalysts

Journal of Energy Chemistry 2021年第1期30卷 41-50,I0002页

作者： Zhengkai Cao Xia Zhang Chunming Xu Xinlu Huang ziming wu Chong Peng Aijun Duan State Key Laboratory of Heavy Oil Processing China University of PetroleumBeijing 102249China Dalian Research Institute of Petroleum and Petrochemicals SINOPECDalian 116041LiaoningChina

Light cycle oil(LCO) with high content of poly-aromatics was difficult to upgrade and convert,which had hindered upgrading fuel quality to meet with the standard of automotive diesel for the purpose of sustainable *** hydrocracking behaviors of typical aromatics in LCO of naphthalene and tetralin were investigated over NiMo and CoMo *** characterization methods including N2-adsoprtion and desorption,ammonia temperature-programmed desorption(NH3-TPD),Pyridine infrared spectroscopy(Py-IR),CO infrared spectroscopy(CO-IR),Raman and X-ray photoelectron spectroscopy(XPS) were applied to determine the properties of different *** results showed that CoMo catalyst with high concentration of S-edges could hydrosaturate more naphthalene to tetralin but exhibit lower yield of high-value light aromatics(carbon numbers less than 10) than NiMo *** catalyst with high concentration of Mo-edges also presented a higher selectivity of converting naphthalene into cyclanes than CoMo ***,the naphthalene and LCO hydrocracking performances were also investigated over different catalysts *** activity evaluation and kinetic analysis results showed that the naphthalene hydrocracking conversion and the yield of light aromatics for CoMo-AY/NiMo-AY grading catalysts were higher than NiMo-AY/CoMo-AY grading catalysts at same condition.A stepwise reaction principle was proposed to explain the high efficiency of CoMo-AY/NiMoAY grading ***,the LCO hydrocracking evaluation results confirmed that CoMo-AY/NiMoAY catalysts grading system with low carbon deposition and high stability could remain high percentage of active phases,which was more efficient to convert LCO to high-octane gasoline.

关键词： Hydrocracking Conversion Selectivity Catalysts grading High-octane gasoline

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Analysis of video head impulse test saccades data in patients with vestibular migraine or probable vestibular migraine

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Journal of Otology 2022年第4期17卷 197-202页

作者： Yi Du Xingjian Liu Lili Ren Yu Wang ziming wu College of Otolaryngology Head and Neck Sury Chinese PLA General HospitalChinese PLA Medical School28 Fuxing RoadBeijingChina National Clinical Research Center for Otolaryngologic Diseases BeijingChina State Key Lab of Hearing Science Ministry of EducationBeijingChina Beijing Key Lab of Hearing Impairment Prevention and Treatment BeijingChina

Objective:Saccades accompanied by normal gain in video head impulse tests(vHIT)are often observed in patients with vestibular migraine(VM).However,they are not considered as an independent indicator,reducing their utility in diagnosing *** better understand clinical features of VM,it is necessary to understand raw saccades ***:Fourteen patients with confirmed VM,45 patients with probable VM(p-VM)and 14 agematched healthy volunteers were included in this *** findings related to spontaneous nystagmus(SN),positional nystagmus(PN),head-shaking nystagmus(HSN),caloric test and vHIT were *** saccades data were exported and numbered by their sequences,and their features ***:VM patients showed no SN,PN or HSN,and less than half of them showed unilateral weakness(UW)on caloric *** first saccades from lateral semicircular canal stimulation were the most predominant for both left and right *** velocity nor time parameters were significantly different when compared between the two *** VM patients(86%)exhibited small saccades,around 35%of the head peak velocity,with a latency of 200e400 *** of saccades were similar in patients with *** four normal subjects showed saccades,all unilateral and seemingly ***:Small saccades involving bilateral semicircular canals with a scattered distribution pattern are common in patients with VM and p-VM.

关键词： Vestibular migraine Probable vestibular migraine Video head impulse test Saccade Data analysis

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Saccades of video head impulse test in Meniere's disease and Vestibular Migraine: What can we learn from?

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Journal of Otology 2023年第2期18卷 79-84页

作者： Yi Du Xingjian Liu Lili Ren Yu Wang Fei Ji Weiwei Guo ziming wu College of Otolaryngology Head and Neck Surgery Chinese PLA General HospitalChinese PLA Medical School28 Fuxing RoadBeijingChina National Clinical Research Center for Otolaryngologic Diseases BeijingChina State Key Lab of Hearing Science Ministry of EducationBeijingChina Beijing Key Lab of Hearing Impairment Prevention and Treatment BeijingChina

Background:Saccades are often observed on video head impulse tests(vHIT)in patients with Meniere's Disease(MD)and Vestibular Migraine(VM).However,their saccadic features are not fully ***:This study aims to identify the saccades characteristics of MD and ***:75 VM patients and 103 definite unilateral MD patients were enrolled in this *** raw saccades were exported and *** VM patients were divided into left and right based on their ears,while the MD patients were separated into affected and unaffected subgroups based on their audiograms and ***:The MD patients have more saccades on the affected side(85%vs.69%),and saccade velocity is more consistent than the contralateral side(shown by the coefficient of variation).The saccades occurrence rates on both sides are similar in VM(77%vs.76%),as are other saccadic *** MD patients have more significant inter-aural differences than the VM patients,manifested in higher velocity(p-value 0.000),earlier arriving(p-value 0.010),and more time-domain gathered(p-value 0.003)on the affected ***:Bilateral saccades are commonly observed in MD and *** contrast to MD,saccades on VM are subtle,scattered,and ***,the MD patients showed inconsistent saccadic distribution with more velocity-uniform saccades on the affected side.

关键词： Meniere's disease Vestibular migraine Saccades Video head impulse test Differential diagnosis

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Comparing saccades in Visually Enhanced Vestibular-Ocular Reflex and video head impulse test in vestibular assessment

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Journal of Otology 2024年第3期19卷 148-157页

作者： Yi Du Xingjian Liu Yu Wang Zhengyan Xu Fei Jia Lili Ren ziming wu College of Otolaryngology Head and Neck Surgery Chinese PLA General HospitalChinese PLA Medical School28 Fuxing RoadBeijingChina National Clinical Research Center for Otolaryngologic Diseases BeijingChina State Key Lab of Hearing Science Ministry of EducationBeijingChina Beijing Key Lab of Hearing Impairment Prevention and Treatment BeijingChina

Objective:This study aimed to develop and evaluate a novel software tool for robust analysis of the Visually Enhanced Vestibular-Ocular Reflex(VVOR)and video head impulse test(vHIT)***:A retrospective study was conducted on 94 patients with Meniere’s Disease(MD),unilateral vestibular hypofunction(UVH),and vestibular migraine(VM).The MATLAB-based VVOR Analysis System and Saccades All in One software were utilized for data *** techniques,VVOR_diff and VVOR_cycle,were deployed for saccade parameter ***:Saccade incidence rates,examined through vHIT,VVOR_diff,and VVOR_cycle,exhibited distinct patterns in MD,UVH,and VM *** instances of multiple saccades within a single cycle were noted on the affected side in MD and UVH *** significant differences in saccade gain and incidence rates between the affected and unaffected sides were evident in MD and UVH ***,high inter-method and intra-method correlations suggested consistency across different methods and potential interactions within ***:The software proved effective in extracting saccades and reducing noise in VVOR data,thereby enhancing the evaluation of vestibular function and potentially improving diagnostic accuracy for vestibular disorders.

关键词： Visually enhanced vestibular-ocular reflex Saccades Frequency-dependent Vestibular-ocular reflex Wavelet analysis

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Clock component OsPRR59 delays heading date by repressing transcription of Ehd3 in rice

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The Crop Journal 2022年第6期10卷 1570-1579页

作者： Yupeng Wang Fuqing wu Shirong Zhou Weiwei Chen Chenyan Li Erchao Duan Jiachang Wang Zhijun Cheng Xin Zhang Qibing Lin Yulong Ren Cailin Lei Xiuping Guo ziming wu Shanshan Zhu Jianmin Wan National Key Facility for Crop Gene Resources and Genetic Improvement Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China National Key Laboratory for Crop Genetics and Germplasm Enhancement Jiangsu Plant Gene Engineering Research CenterNanjing Agricultural UniversityNanjing 210095JiangsuChina Key Laboratory of Crop Physiology Ecology and Genetic BreedingMinistry of EducationJiangxi Agricultural UniversityNanchang 330045JiangxiChina

Heading date(or flowering time),an important agronomic trait in crop species,is closely associated with regional adaptation and *** of the Pseudo-Response Regulator(PRR)family play key roles in regulating ***,their role and molecular mechanism controlling heading date in rice is not very ***,we identified rice OsPRR protein,OsPRR59,which delayed heading under longday ***59 positively regulates yield by affecting plant height,secondary branches number per panicle,grain number per panicle,seed setting rate,and grain weight per ***59 is expressed in most tissues and its protein is localized to the *** also found that OsPRR59 directly binds to the promoter of Ehd3 to inhibit its *** with the WT,osprr59 ehd3 showed a significantly delayed heading phenotype,as did the ehd3 *** was opposite to the phenotype of the osprr59 mutant,confirming that Ehd3 acted downstream of OsPRR59 in regulating rice *** results identified a direct regulator of Ehd3,and revealed a novel molecular mechanism of clock component OsPRR proteins in regulating heading date and provide a new genetic resource for fine-tuning heading date in rice.

关键词： Circadian clock Ehd3 Heading date Oryza sativa Pseudo-response regulator

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Trends in Incidence of HIV and Syphilis Among Men Who Have Sex with Men—Tianjin Municipality,China,2013-2022

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China CDC weekly 2024年第27期6卷 651-657页

作者： Yan Guo Fangfang Chen Hui Gong ziming wu Xinying Zhang Tielin Ning Zhongquan Liu Jianyun Bai Long Li Jie Yang Fangning Zhao Jinyu Hou Maohe Yu Houlin Tang STD&AIDS Control and Prevention Section Tianjin Center for Disease Control and PreventionTianjinChina National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases National Center for AIDS/STD Control and PreventionChinese Center for Disease Control and PreventionBeijingChina STD&AIDS Control and Prevention department Tianjin Hongqiao District Center for Disease Control and PreventionTianjinChina Tianjin Shenlan Public Health Counseling Service Center TianjinChina Tianjin Key Laboratory of Pathogenic Microbiology of Infectious Disease Tianjin Centers for Disease Control and PreventionTianjinChina

Summary What is already known about this topic?Given the common modes of transmission,outbreaks of both human immunodeficiency virus(HIV)and syphilis are primarily observed in men who have sex with men(MSM).However,minimal research has been conducted to concurrently evaluate the rates and trends of HIV and syphilis incidence within this community in *** is added by this report?

关键词： Incidence primarily immunodeficiency

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Zyxin promotes hepatocellular carcinoma progression via the activation of AKT/mTOR signaling pathway

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Oncology Research 2023年第5期31卷 805-817页

作者： TIANYING CAI JUNJIE BAI PENG TAN ZHIWEI HUANG CHEN LIU ziming wu YONGLANG CHENG TONGXI LI YIFAN CHEN JIAN RUAN LIN GAO YICHAO DU WENGUANG FU Department of Hepatobiliary Surgery Affiliated Hospital of Southwest Medical UniversityLuzhou646000China Biobank The Affiliated Hospital of Southwest Medical UniversityLuzhou646000China Academician(Expert)Workstation of Sichuan Province The Affiliated Hospital of Southwest Medical UniversityLuzhou646000China Department of Medical Oncology First Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou310000China Department of Health Management The Affiliated Hospital of Southwest Medical UniversityLuzhou646000China

Hepatocellular carcinoma(HCC)is a common malignancy that is driven by multiple genes and *** aim of this study was to investigate the role and specific mechanism of the actin-interacting protein zyxin(ZYX)in *** found that the expression of ZYX was significantly higher in HCC tissues compared to that in normal liver *** addition,overexpression of ZYX in hepatoma cell lines(PLC/PRF/5,HCCLM3)enhanced their proliferation,migration and invasion,whereas ZYX knockdown had the opposite effects(SK HEP-1,Huh-7).Furthermore,the change in the expression levels of ZYX also altered that of proteins related to cell cycle,migration and *** results were obtained with xenograft *** AKT/mTOR signaling pathway is one of the key mediators of cancer *** ZYX overexpression upregulated the levels of phosphorylated AKT/mTOR proteins,its knockdown had the opposite *** addition,the AKT inhibitor MK2206 neutralized the pro-oncogenic effects of ZYX on the HCC cells,whereas the AKT activator SC79 restored the proliferation,migration and invasion of HCC cells with ZYX *** together,ZYX promotes the malignant progression of HCC by activating AKT/mTOR signaling pathway,and is a potential therapeutic target in HCC.

关键词： Zyxin Hepatocellular carcinoma AKT/mTOR Proliferation Migration Invasion

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直流电刺激前庭诱发肌源性电位研究现状与进展

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中华耳科学杂志 2023年第4期21卷 533-538页

作者：徐正燕吴子明中国人民解放军总医院耳鼻咽喉头颈外科医学部听觉与平衡觉全国重点实验室国家耳鼻咽喉疾病临床医学研究中心聋病教育部重点实验室聋病防治北京市重点实验室北京100853

前庭诱发肌源性电位(vestibular-evoked myogenic potentials,VEMPs)目前广泛用于前庭疾病,尤其是前庭耳石器及其传导通路相关疾病的诊断。其刺激方式主要有气导刺激、骨导刺激和直流电刺激三种。气导和骨导刺激是主要的诱发方法,直流... 详细信息

前庭诱发肌源性电位(vestibular-evoked myogenic potentials,VEMPs)目前广泛用于前庭疾病,尤其是前庭耳石器及其传导通路相关疾病的诊断。其刺激方式主要有气导刺激、骨导刺激和直流电刺激三种。气导和骨导刺激是主要的诱发方法,直流电刺激直接刺激前庭传入神经,临床和基础研究还不成熟,故本文主要对直流电刺激前庭诱发肌源性电位的理论依据、记录方法、结果分析和临床应用进行综述。

关键词：直流电刺激前庭诱发肌源性电位研究进展

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美国耳鼻咽喉学会良性阵发性位置性眩晕指南更新及再思考

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临床耳鼻咽喉头颈外科杂志 2019年第3期33卷 207-209页

作者：吴子明张素珍解放军总医院耳鼻咽喉头颈外科眩晕诊疗中心北京100853

良性阵发性位置性眩晕(BPPV)的诊断与治疗是前庭医学领域近10年最大的亮点,也是这一领域被广泛关注的主要原因之一。但是,因为关注者众多,以及认识的水平和角度差异性大,所以,对于这种可以和感冒相比拟的疾病,尤其需要依据科学的理论加... 详细信息

良性阵发性位置性眩晕(BPPV)的诊断与治疗是前庭医学领域近10年最大的亮点,也是这一领域被广泛关注的主要原因之一。但是,因为关注者众多,以及认识的水平和角度差异性大,所以,对于这种可以和感冒相比拟的疾病,尤其需要依据科学的理论加以梳理,纠正简单问题的误判、误导以及'大众化'的误读,可以更大程度地减少由此带来的学术上的错误认识和患者的误治。国内2017年已发布BPPV指南(中华医学会耳鼻咽喉头颈外科分会),该指南是国内临床BPPV诊治的指导性文件。

关键词：眩晕指南

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功能性眩晕-眩晕诊治的新高度

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中华耳科学杂志 2017年第6期15卷 613-618页

作者：吴子明张素珍解放军总医院耳鼻咽喉头颈外科眩晕诊疗中心

近30年来,行为方式对空间定位和平衡的认识已有很多进步,功能性和心因性疾病引起前庭症状也越来越普遍,也比结构性(器质性)前庭疾病更常见。目前正在完善中的国际前庭疾病分类瞄准这一迫切解决的问题,在即将发布的ICD-11中,正式命名、... 详细信息

近30年来,行为方式对空间定位和平衡的认识已有很多进步,功能性和心因性疾病引起前庭症状也越来越普遍,也比结构性(器质性)前庭疾病更常见。目前正在完善中的国际前庭疾病分类瞄准这一迫切解决的问题,在即将发布的ICD-11中,正式命名、定义功能性眩晕这一常见的慢性眩晕类型。功能性眩晕不同于心因性眩晕,但心因性眩晕如果不干预,会影响功能性眩晕的治疗效果。现今,眩晕的诊断模式也将打破二元论的桎梏,呈现结构、功能与心因三方面的格局。今后,动态姿势评价、磁共振成像等新技术手段将进一步推进该领域的认识和发展。功能性眩晕的治疗包括患者教育、前庭康复以及认知行为治疗。功能性眩晕诊治的多学科合作是这一疾病临床诊治的方向。而患者首诊的耳科或神经耳科专家将扮演核心角色。

关键词：慢性主观性眩晕功能磁共振成像国际疾病分类第11版国际前庭疾病分类持续姿势感知性眩晕恐怖性姿势性眩晕空间运动不适视觉性眩晕

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