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EjBZR1 represses fruit enlargement by binding to the EjCYP90 promoter in loquat

Horticulture Research 2021年第1期8卷 2068-2081页

作者： Wenbing Su zikun Shao Man Wang Xiaoqing Gan Xianghui yang Shunquan Lin State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources and Key Laboratory of Innovation and Utilization of Horticultural Crop Resources in South China(Ministry of Agriculture and Rural Affairs) College of HorticultureSouth China Agricultural University510642 GuangzhouChina Fruit Research Institute Fujian Academy of Agricultural Science350013 FuzhouChina Key Laboratory of Loquat Germplasm Innovation and Utilization Putian University351100 PutianChina

Loquat(Eriobotrya japonica)is a subtropical tree that bears fruit that ripens during late *** size is one of the dominant factors inhibiting the large-scale production of this fruit *** date,little is known about fruit size *** this study,we first discovered that cell size is more important to fruit size than cell number in loquat and that the expression of the EjBZR1 gene is negatively correlated with cell and fruit ***-induced gene silencing(VIGS)of EjBZR1 led to larger cells and fruits in loquat,while its overexpression reduced cell and plant size in ***,both the suppression and overexpression of EjBZR1 inhibited the expression of brassinosteroid(BR)biosynthesis genes,especially that of *** experiments indicated that EjCYP90A,a cytochrome P450 gene,is a fruit growth activator,while EjBZR1 binds to the BRRE(CGTGTG)motif of the EjCYP90A promoter to repress its expression and fruit cell ***,our results demonstrate a possible pathway by which EjBZR1 directly targets EjCYP90A and thereby affects BR biosynthesis,which influences cell expansion and,consequently,fruit *** findings help to elucidate the molecular functions of BZR1 in fruit growth and thus highlight a useful genetic improvement that can lead to increased crop yields by repressing gene expression.

关键词： thereby finding expansion

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Silver-catalyzed unstrained C(CO)–alkyl bond scission via[3+2]/retro-[3+2]cycloaddition of ketones with N-isocyanoiminotriphenylphosphorane

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Science China Chemistry 2021年第7期64卷 1157-1163页

作者： zikun Wang Linxuan Li Xueying Zhang Xihe Bi Department of Chemistry Northeast Normal UniversityChangchun 130024China State Key Laboratory of Elemento-Organic Chemistry Nankai UniversityTianjin 300071China

C(CO)–alkyl bonds are ubiquitous in a variety of organic molecules,and their selective activation and functionalization are important for the reconstruction of simple ketones into valuable building ***,due to the thermodynamic and kinetic stability,the cleavage and transformation of the unstrained C(CO)–alkyl bonds remain a significant ***,we report a novel silver-catalyzed scission of the unstrained C(CO)–alkyl bond of ketones by reacting with N-isocyanoiminotriphenylphosphorane(NIITP)under mild *** method could transform a variety of unstrained ketones into iminophosphoranes and nitriles in high *** and computational studies disclosed the reaction proceeded through an unprecedented[3+2]/retro-[3+2]cycloaddition mechanism.

关键词： silver-catalyzed C-C bond scission unstrained ketones tertiary alcohol intermediates cycloaddition

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Practical evaluation of prelithiation strategies for next-generation lithium-ion batteries

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Carbon Energy 2023年第8期5卷 55-77页

作者： Shiming Chen Zhen Wang Meng Zhang Xiaoze Shi Lu Wang Weifeng An zikun Li Feng Pan Luyi yang School of Advanced Materials Peking University Shenzhen Graduate SchoolShenzhenChina BTR New Material Group Co. Ltd.ShenzhenChina R&D Institute Shenzhen BAK Power Battery Co.Ltd.ShenzhenChina

With the increasing market demand for high-performance lithium-ion batteries with high-capacity electrode materials,reducing the irreversible capacity loss in the initial cycle and compensating for the active lithium loss during the cycling process are critical *** recent years,various prelithiation strategies have been developed to overcome these *** these approaches are carried out under a wide range of conditions,it is essential to evaluate their suitability for large-scale commercial *** this review,these strategies are categorized based on different battery assembling stages that they are implemented in,including active material synthesis,the slurry mixing process,electrode pretreatment,and battery ***,their advantages and disadvantages in commercial production are discussed from the perspective of thermodynamics and *** review aims to provide guidance for the future development of prelithiation strategies toward commercialization,which will potentially promote the practical application of next-generation high-energy-density lithium-ion batteries.

关键词： high-energy-density irreversible capacity loss lithium-ion batteries practical application prelithiation

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A physics-informed neural network for simulation of finite deformation in hyperelastic-magnetic coupling problems

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Applied Mathematics and Mechanics(English Edition) 2024年第10期45卷 1717-1732页

作者： WANG Lei LUO zikun LU Mengkai TANG Minghai Department of Engineering Mechanics College of Mechanics and Engineering SciencesHohai UniversityNanjing 211100China School of Mechanical Engineering and Mechanics Ningbo UniversityNingbo 315211Zhejiang ProvinceChina

Recently,numerous studies have demonstrated that the physics-informed neural network(PINN)can effectively and accurately resolve hyperelastic finite deformation *** this paper,a PINN framework for tackling hyperelastic-magnetic coupling problems is *** the solution space consists of two-phase domains,two separate networks are constructed to independently predict the solution for each phase *** addition,a conscious point allocation strategy is incorporated to enhance the prediction precision of the PINN in regions characterized by sharp *** the developed framework,the magnetic fields and deformation fields of magnetorheological elastomers(MREs)are solved under the control of hyperelastic-magnetic coupling *** examples are provided and contrasted with the reference results to validate the predictive accuracy of the proposed ***,the advantages of the proposed framework in solving hyperelastic-magnetic coupling problems are validated,particularly in handling small data sets,as well as its ability in swiftly and precisely forecasting magnetostrictive motion.

关键词： physics-informed neural network(PINN) deep learning hyperelastic-magnetic coupling finite deformation small data set

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Physical and numerical investigations of target stratum selection for ground hydraulic fracturing of multiple hard roofs

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International Journal of Mining Science and Technology 2024年第5期34卷 699-712页

作者： Binwei Xia Yanmin Zhou Xingguo Zhang Lei Zhou zikun Ma State Key Laboratory of Coal Mine Disaster Dynamics and Control Chongqing UniversityChongqing 400044China School of Resources and Safety Engineering Chongqing UniversityChongqing 400044China

Ground hydraulic fracturing plays a crucial role in controlling the far-field hard roof,making it imperative to identify the most suitable target stratum for effective *** experiments are conducted based on engineering properties to simulate the gradual collapse of the roof during longwall top coal caving(LTCC).A numerical model is established using the material point method(MPM)and the strain-softening damage constitutive model according to the structure of the physical *** simulations are conducted to analyze the LTCC process under different hard roofs for ground hydraulic *** results show that ground hydraulic fracturing releases the energy and stress of the target stratum,resulting in a substantial lag in the fracturing of the overburden before collapse occurs in the hydraulic fracturing *** hydraulic fracturing of a low hard roof reduces the lag effect of hydraulic fractures,dissipates the energy consumed by the fracture of the hard roof,and reduces the abutment ***,it is advisable to prioritize the selection of the lower hard roof as the target stratum.

关键词： Target stratum selection Ground hydraulic fracturing Hard roof control Fracture network Material point method

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Bleustein-Gulyaev waves in a functionally graded piezoelectric material layered structure

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Science China(Physics,Mechanics & Astronomy) 2009年第4期52卷 613-625页

作者： CAO Xiaoshan JIN Feng WANG zikun LU TianJian MOE Key Laboratory for Strength and Vibration School of AerospaceXi’an Jiaotong UniversityXi’an 710049China

This work presents a theoretical study of the propagation behavior of Bleustein-Gulyaev waves in a layered structure consisting of a functionally graded piezoelectric material(FGPM) layer and a transversely isotropic piezoelectric substrate. The influence of the graded variation of FGPM coefficients on the dispersion relations of Bleustein-Gulyaev waves in the layered structure is investigated. It is demonstrated that,for a certain frequency range of Bleustein-Gulyaev waves,the mechanical perturbations of the particles are restricted in the FPGM layer and the phase velocity is independent of the electrical boundary conditions at the free surface. Results presented in this study can not only provide further insight on the electromechanical coupling behavior of surface waves in FGPM layered structures,but also lend a theoretical basis for the design of high-performance surface acoustic wave(SAW) devices.

关键词： Bleustein-Gulyaev waves functionally graded piezoelectric material electro-mechanical coupling factor surface acoustic wave device

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AXISYMMETRIC BOUNDARY-VALUE PROBLEMS IN A PIEZOELECTRIC MEDIUM

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Acta Mechanica Solida Sinica 1998年第2期11卷 104-112页

作者： Zheng Bailin Wang zikun Ji Xing Tongji Univ Dept Engn Mech & Technol Shanghai 200092 Peoples R China Xian Jiao Tong Univ Dept Mech Engn Xian Peoples R China

Based on the general solution of three-dimensional problems inpiezoelectric medium, with the method of Green's functins~[2],axisymmetric boundary-value problems are discussed. The purpose ofthis research is for analyzing the effective on mechanics andelectricity of the piezoelectric ceramics caused by voids andinclusions. The displacement, traction and electric Green's functionscorresponding to circular ring loads acting in the interior of apiezoelectric ceramic are obtained. A cylindrical coordinate systemis employed and Hankel transform are applied with respect to radialcoor- dinates. Explicit solutions for Green's functions are presentedin terms of infinite integrals of Lipshitz- Hankel type. By solving atraction boundary-value problem, the solution scheme is illustrate.

关键词： piezoelectric ceramics voids and inclusions Hankel transforms

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Unveiling the interaction mechanisms of key functional microorganisms in the partial denitrification-anammox process induced by COD

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Frontiers of Environmental Science & Engineering 2023年第8期17卷 153-165页

作者： Guangjiao Chen Lan Lin Ying Wang zikun Zhang Wenzhi Cao Yanlong Zhang Key Laboratory of Marine Environmental Science College of the Environment and EcologyXiamen UniversityXiamen 361102China Fujian Key Laboratory of Coastal Pollution Prevention and Control College of Environment and EcologyXiamen UniversityXiamen 361102China Department of Civil and Environmental Engineering Graduate School of EngineeringTohoku UniversitySendaiMiyagi 980-8579Japan

Partial denitrification-anammox(PD-anammox)is an innovative process to remove nitrate(NO_(3)^(–)–N)and ammonia(NH4+–N)simultaneously from *** operation of the PD-anammox process relies on the synergy and competition between anammox bacteria and ***,the mechanism of metabolic between the functional bacteria in the PD-anammox system remains unclear,especially in the treatment of high-strength *** kinetics of nitrite(NO_(2)^–N)accumulation during denitrification was investigated using the Michaelis-Menten equation,and it was found that low concentrations of NO_(3)^–N had a more significant effect on the accumulation of NO_(2)^–N during *** matter was a key factor to regulate the synergy of anammox and denitrification,and altered the nitrogen removal *** competition for NO_(2)^–N caused by high COD concentration was a crucial factor that affecting the system *** sequencing techniques demonstrated that excess organic matter promoted the relative abundance of the Denitratesoma genus and the nitrite reductase gene nirS,causing the denitrifying bacteria Denitratisoma to compete with Cadidatus Kuenenia for NO_(2)^–N,thereby affecting the stability of the *** carbon and nitrogen removal between partial denitrifiers and anammox bacteria can be effectively achieved by controlling the COD and COD/NO_(3)^(–)N.

关键词： PD-anammox process Nitrite accumulation COD Microbial interaction

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Mechanical characterization of a 10-MJ HTS SMES magnet wound by quasiisotropic strands and directly stacked tape conductors

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Superconductivity 2023年第1期5卷 69-74页

作者： zikun Zhao Yinshun Wang Yubo Gao Zhao yang ZhuYong Li Wei Pi State Key Lab.of New Energy Renewable Power System North China Electric Power UniversityBeijing 102206China Key Lab.of HV and EMC Beijing North China Electric Power UniversityBeijing 102206China Energy Singularity Energy Technolo-gy(shanghai)Co. LtdShangHai 200000China

A 10‐MJ‐class superconducting magnetic energy storage(SMES)magnet is designed and optimized in this study using quasi‐isotropic strands and stacked‐tape *** order to ensure the stable operation of SMES systems,it is necessary to evaluate the mechanical properties risk caused by the Lorentz ***,in this study,the magnetic stress caused by the Lorentz force is analyzed using the finite element *** results show that the tapes near the inner diameter of the magnet are subjected to a higher stress and require considerable *** the maximum stress is increased by two times due to the presence of the screening current,it is within the safety *** screening current does not vanish after the discharge *** discharge,the coil is still subjected to a stress on the other of a few MPa.

关键词： Lorentz force Quasi‐isotropic strand Superconducting magnetic energy storage Screening current Weibull distribution

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椎间盘退行性变与473种肠道菌群的关系:芬兰数据库大数据信息可借鉴的意义

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中国组织工程研究 2025年第20期29卷 4369-4378页

作者：王梓焜李树栋高泷范书豪李城孟纯阳山东第一医科大学(山东省医学科学院) 山东省济南市250117 山东中医药大学第一临床医学院山东省济南市250355 济宁医学院临床医学院山东省济宁市272067 济宁医学院附属医院脊柱外科山东省济宁市272000

背景:有研究表明,调节肠道菌群可能会影响椎间盘退变的进程。然而,肠道菌群与椎间盘退变的因果关系尚不清楚。目的:采用孟德尔随机化方法来评估肠道菌群与椎间盘退变之间的潜在因果关系。方法:应用公开发表最新的473种肠道菌群的全基因... 详细信息

背景:有研究表明,调节肠道菌群可能会影响椎间盘退变的进程。然而,肠道菌群与椎间盘退变的因果关系尚不清楚。目的:采用孟德尔随机化方法来评估肠道菌群与椎间盘退变之间的潜在因果关系。方法:应用公开发表最新的473种肠道菌群的全基因组关联分析汇总统计数据和芬兰数据库R11中的椎间盘退变的全基因组关联分析汇总数据(椎间盘退变病例46 205例和对照组322 314例)。采用逆方差加权法、MR-Egger回归法、加权中位数法、加权模型法和简单模型法来研究肠道菌群与椎间盘退变之间的因果关系。敏感性分析用于检验孟德尔随机化分析结果是否可靠。反向孟德尔随机化以全部肠道菌群作为结局进行效应分析和敏感性分析。结果与结论:(1)正向孟德尔随机化的逆方差加权法结果显示,毛螺菌目,UBA-6960科、嗜热厌氧杆菌科、盐单胞菌科、丛毛单菌属、戈登氏菌属和欧陆森氏菌属与椎间盘退变呈现正相关。短螺旋体目、假单胞菌目、短螺旋菌科、CAG-776属、螺杆菌属、CAG-448种sp003150135、CAG-776种sp000438195、布劳特氏菌种-A sp000285855和汉逊布劳氏菌种与椎间盘退变呈现负相关。(2)反向孟德尔随机化结果显示,椎间盘退变与玫瑰巴氏菌属、地电细菌属C、弗氏埃希菌种、弗氏丙酸杆菌种、UBA-1777种sp900319835、铜绿假单胞菌种和韦氏芽孢杆菌种呈正相关,与明串珠菌属、普雷沃氏菌种sp000434975、布劳特氏菌种-A sp000285855、CAG-194种sp002441865和CAG-590种sp000431135呈负相关。(3)双向敏感性分析均未发现存在异质性或水平多效性。(4)上述结果说明,基于芬兰数据库探究肠道菌群与椎间盘退变的因果关系,为临床上椎间盘退变的早期预测及治疗探索了新的生物标志物。另外,对于中国生物医学研究,可以借鉴建立大型数据库,整合多中心的医疗数据,为肠道菌群与椎间盘退变关系的研究提供坚实基础,与其他国家的科研团队加强交流与合作,共同推动肠道菌群与疾病关系的研究,为全球医学发展作出贡献。

关键词：孟德尔随机化椎间盘退变肠道菌群全基因组关联分析单核苷酸多态性逆方差加权法水平多效性敏感性分析

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