检索结果-南通市图书馆

同方期刊数据库

在线全文

学校读者我要写书评

暂无评论

大型高炉炉缸侧壁温度控制技术分析

山西冶金 2024年第4期47卷 138-140页

作者：徐晓娟王超王光远徐自军中检集团公信安全科技有限公司山东枣庄277100

高炉炉缸侧壁温度升高会严重威胁高炉寿命,为了有效控制高炉炉缸侧壁温度,延长高炉寿命。以目前我国大型高炉炉缸侧壁温度统计数据为切入点,在炉缸结构及材料要求的基础上,从传热学角度分析了炉缸侧壁温度的影响因素,提出了相应的控制... 详细信息

高炉炉缸侧壁温度升高会严重威胁高炉寿命,为了有效控制高炉炉缸侧壁温度,延长高炉寿命。以目前我国大型高炉炉缸侧壁温度统计数据为切入点,在炉缸结构及材料要求的基础上,从传热学角度分析了炉缸侧壁温度的影响因素,提出了相应的控制技术。结果表明,控制冶炼强度、稳定铁口深度、提高死料柱孔隙率、炉缸压浆、加钛护炉、加强冷却制度管理等技术措施,可有效控制炉缸侧壁温度。

关键词：大型高炉炉缸侧壁冷却壁炭砖温度控制

Distribution and invasion of Spartina alterniflora within the Jiaozhou Bay monitored by remote sensing image

在线全文

学校读者我要写书评

暂无评论

Acta Oceanologica Sinica 2022年第6期41卷 31-40页

作者： Jianbu Wang Zhaoyang Lin Yuanqing Ma Guangbo Ren zijun xu Xiukai Song Yi Ma Andong Wang Yajie Zhao Laboratory of Marine Physics and Remote Sensing First Institute of OceanographyMinistry of Natural ResourcesQingdao 266061China School of Information and Electrics Beijing Institute of TechnologyBeijing 100081China Shandong Marine Resources and Environment Research Institute Shandong Provincial Key Laboratory of Restoration for Marine EcologyYantai 264006China North China Sea Environmental Monitoring Center State Oceanic AdministrationQingdao 266033China Shandong Yellow River Delta National Nature Reserve Administration Committee Dongying 257091China

Spartina alterniflora as an alien invasive plant,poses a serious threat to the ecological functions of the coastal wetland of the Jiaozhou *** of 2019,the distribution area of *** in the Jiaozhou Bay has reached more than 500 hm^(2).For this reason,combined with field surveys,remote sensing monitoring of the invasion *** in the Jiaozhou Bay has been carried *** accurately identify *** within the Jiaozhou Bay coastal wetland,we used a new method which is an implement of deep convolutional neural network,and by which we got a higher accuracy than the traditional *** on distribution of *** extracted by the proposed method,the temporal and spatial distribution characteristics of *** were *** then combined with environmental factors,the invasion mechanism of *** in the Jiaozhou Bay was analyzed in *** the monitoring results,it can be seen that *** in Jiaozhou Bay is mainly distributed in the beaches near the Yanghe River Estuary and its southern side,the Dagu River Estuary and the Nü*** alterniflora first broke out near the Yanghe River Estuary and gradually spread to the tidal flats near the Nü*** Dagu River Estuary is dominated by ***,whose area has not changed much over the years,and a small amount of *** has invaded later.

关键词： Spartina alterniflora remote sensing coastal wetland deep residual network

基于VGG⁃19和MMD卷积神经网络模型的国画风格迁移

在线全文

学校读者我要写书评

暂无评论

现代计算机 2024年第3期30卷 61-65,70页

作者：徐子俊胡予昕陆文浩宋兴睿刘哲江汉大学人工智能学院武汉430056

卷积神经网络因效果强大而被广泛应用于图像识别,在提取图像特征方面有极大的进步。由于风格迁移技术主要是针对西方油画,而国画是一种传统的中国艺术风格,其在风格迁移方向上缺乏广泛的应用。设计以国画代替西方油画作为风格图像,以自... 详细信息

卷积神经网络因效果强大而被广泛应用于图像识别,在提取图像特征方面有极大的进步。由于风格迁移技术主要是针对西方油画,而国画是一种传统的中国艺术风格,其在风格迁移方向上缺乏广泛的应用。设计以国画代替西方油画作为风格图像,以自然景观照片作为内容图像,探究传统国画经过卷积神经网络后的提取效果。实验依据VGG算法模型并结合TensorFlow 2框架,对采集的数据集进行预处理,采集像素制成数据矩阵,输入VGG⁃19浅层模型进行训练,通过MMD最小化分布特征图差异,增强卷积层的目标效果。该方法取得比较满意的结果,可为风格迁移转换的研究提供更多参考。

关键词：卷积层神经网络 VGG⁃19 MMD 风格迁移算法

Solvability of a Elliptic-Parabolic(Hyperbolic)Type Chemotaxis System in a Bounded Domain

在线全文

学校读者我要写书评

暂无评论

Journal of Partial Differential Equations 2018年第4期31卷 322-332页

作者： xu zijun School of Mathematics Jinzhong Universityjinzhong 030619China

In this paper,we use contraction mapping principle and operator-theoretic approach to establish local solvability of the elliptic-parabolic(hyperbolic)Type Chemotaxis *** add让ion,global solvabil让y of the systems is ... 详细信息

关键词： Elliptic-parabolic(hyperbolic)system chemotaxis model local existence global existence

SLC22A3 methylation-mediated gene silencing predicts adverse prognosis in acute myeloid leukemia

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

SLC22A3 methylation-mediated gene silencing predicts adverse...

The downregulation of circ＿0059707 in acute myeloid leukemia promotes cell growth and inhibits apoptosis by regulating miR-1287-5p

2022CCTB中国肿瘤标志物学术大会暨中国整合肿瘤学...

作者： Yu Gu zijun xu Jingdong Zhou Jun Qian Affiliated People’s Hospital of Jiangsu University

Background:We screened out several hypermethylated solute carrier(SLC) family genes in acute myeloid leukemia(AML) by reduced representation bisulfite sequencing(RRBS).SLC22A3encodes an organic cation transport protein,which is critical for drug transportation and cellular ***22A3 is significantly downregulated and associated with tumor progression and worse prognosis in a variety of solid ***,there are no data available regarding the role of SLC22A in *** study aimed to explore the regulatory mechanism of DNA methylation on SLC22A3 expression,as well as its clinical significance in AML *** and Results:SLC22A3 was identified as the sole prognosis-associated gene among SLCs based on TCGA and Beat AML *** marrow mononuclear cells(BMMNCs)from AML,MDS patients and healthy donors were enrolled in this ***22A3methylation was significantly increased in AML compared with controls and MDS patients,and meanwhile the expression level of SLC22A3 was ***22A3 hypermethylation presented obvious association with some specific clinical characteristics and affected survival time of AML patients as an independent risk ***22A3 expression changed regularly as the disease complete remissions and *** drug5-aza-2’-deoxycytidine(DAC) activated transcription and increased mRNA expression of SLC22A3 in leukemia cell lines and AML fresh *** of SLC22A3 in leukemia cells enhanced cell proliferation and suppressed cell *** from public programs were used for auxiliary screening of probable molecular mechanisms of SLC22A3in antileukemia ***:Our results showed that increased methylation and decreased expression of SLC22A3 may be indicators of poor prognosis in ***-silenced SLC22A3expression may have potential guiding significance on anti-leukemia effect of DAC.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

The downregulation of circ＿0059707 in acute myeloid leukemi...

Predicting the Influence of Circ＿0059706 Expression on Prognosis in Patients with Acute Myeloid Leukemia using Classical Statistics and Machine Learning

2022CCTB中国肿瘤标志物学术大会暨中国整合肿瘤学...

作者： Jichun Ma Xiangmei Wen zijun xu Peihui Xia Ye Jin Jiang Lin Jun Qian Affiliated People’s Hospital of Jiangsu University

Acute myeloid leukemia(AML) is the most common type of hematological ***,increasing reports have shown that many circular RNAs can act as effective targets for ***,the roles of circ059707 in AML remain largely *** this study,we found that the expression levels of circ059707 were significantly decreased in AML patients than in normal healthy controls(P<0.001).Low expression levels of circ059707 were also associated with a poor ***,circ059707 overexpression inhibited cell growth,promoted apoptosis in leukemia cells,compared with control ***059707and empty plasmid transfected cells were injected subcutaneously into BALB/c nude *** found tumor volume of mice in the circ059707 group was significantly lower than in the control(P<0.01).Nuclear pyknosis,nuclear fragmentation,nuclear dissolution,and cell necrosis were observed in circ059707 group by HE *** analysis showed that 25 microRNAs(miRNAs),including miR-1287-5p,hsa-miR-1825,and hsa-miR-326,may be potential targets for circ059707;of these miRNAs were analyzed and intersected by the GEO database GSE51908 and *** R-1287-5p were lower in AML patients compared with controls in both the GSE51908 and GSE142700 ***,we demonstrated that miR-1287-5p expression was down-regulated in AML patients and up-regulated in overexpressed circ059707 ***,our research demonstrated that the downregulation of circ059707 was highly evident in de novo AML *** also demonstrated that circ059707 inhibited cell growth and promoted apoptosis by up-regulating miR-1287-5p.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Predicting the Influence of Circ＿0059706 Expression on Prog...

ALK阳性非小细胞肺癌靶向治疗耐药机制及治疗管理的研究进展

2022CCTB中国肿瘤标志物学术大会暨中国整合肿瘤学...

作者： Jichun Ma Xiangmei Wen zijun xu Peihui Xia Ye Jin Jiang Lin Jun Qian Affiliated People’s Hospital of Jiangsu University

Various circular RNA(circRNA) molecules are abnormally expressed in acute myeloid leukemia(AML),and associated with disease occurrence and development,as well as patient *** roles of circ

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

中国肿瘤临床 2022年第5期49卷 254-258页

作者：徐子钧胡继繁刘子玲吉林大学第一医院肿瘤中心肿瘤科长春市130012

目前,肺癌仍是世界上最常见的恶性肿瘤,位居癌症死亡原因的第1位,随着靶向治疗的发展,死亡率已显著降低。间变性淋巴瘤激酶(anaplastic lymphoma kinase,ALK)作为对治疗有显著反应的非小细胞肺癌(non-small cell lung carcinoma,NSCLC)... 详细信息

目前,肺癌仍是世界上最常见的恶性肿瘤,位居癌症死亡原因的第1位,随着靶向治疗的发展,死亡率已显著降低。间变性淋巴瘤激酶(anaplastic lymphoma kinase,ALK)作为对治疗有显著反应的非小细胞肺癌(non-small cell lung carcinoma,NSCLC)基因型,发展至今已有三代针对其靶位的间变性淋巴瘤激酶酪氨酸激酶抑制剂(anaplastic lymphoma kinase-tyrosine kinase inhibitors,ALK-TKIs),新一代的ALK-TKIs比上一代具有更为广泛的作用位点覆盖范围及更强的药物组织穿透能力。发展前路可观,但仍无法规避耐药问题,随着多种ALK抑制剂应用及联合治疗的选择增多,新的耐药后突变、复合突变以及其他多种耐药机制已逐渐被关注。与此同时,相关早期诊断及预后标志物也被发掘证实。NSCLC耐药机制及检测手段在不断更新,治疗以基于基因依赖性的个体化治疗为主,以期通过对多种耐药方式的介入,使得NSCLC逐渐转变为慢性病。本文归纳介绍了ALK抑制剂应用于NSCLC的现状及耐药机制,耐药后治疗策略及诊断和预后标志物的进展,旨在为ALK阳性NSCLC的诊治及耐药后管理策略提供参考依据。

关键词：间变性淋巴瘤激酶非小细胞肺癌靶向治疗耐药

Coxsackievirus B3 HFMD animal models in Syrian hamster and rhesus monkey

在线全文

学校读者我要写书评

暂无评论

Virologica Sinica 2024年第2期39卷 290-300页

作者： Suqin Duan Wei Zhang Yongjie Li Yanyan Li Yuan Zhao Weihua Jin Quan Liu Mingxue Li Wenting Sun Lixiong Chen Hongjie xu Jie Tang Jinghan Hou zijun Deng Fengmei Yang Shaohui Ma Zhanlong He Institute of Medical Biology Chinese Academy of Medical Sciences Medical Primate Research Center Peking Union Medical CollegeYunnan Key Laboratory of Vaccine Research Development on Severe Infectious DiseaseKunming650118China

Coxsackievirus B3(CVB3)is the pathogen causing hand,foot and mouth disease(HFMD),which manifests across a spectrum of clinical severity from mild to ***,CVB3-infected mouse models mainly demonstrate viral myocarditis and pancreatitis,failing to replicate human HFMD *** several enteroviruses have been evaluated in Syrian hamsters and rhesus monkeys,there is no comprehensive data on *** this study,we have first tested the susceptibility of Syrian hamsters to CVB3 infection via different *** results showed that Syrian hamsters were successfully infected with CVB3 by intraperitoneal injection or nasal drip,leading to nasopharyngeal colonization,acute severe pathological injury,and typical HFMD ***,the nasal drip group exhibited a longer viral excretion cycle and more severe pathological *** the subsequent study,rhesus monkeys infected with CVB3 through nasal drips also presented signs of HFMD symptoms,viral excretion,serum antibody conversion,viral nucleic acids and antigens,and the specific organ damages,particularly in the ***,there were no significant differences in myocardial enzyme levels,and the clinical symptoms resembled those often associated with common,mild *** summary,the study successfully developed severe Syrian hamsters and mild rhesus monkey models for CVB3-induced *** models could serve as a basis for understanding the disease pathogenesis,conducting pre-trial prevention and evaluation,and implementing post-exposure intervention.

关键词： Coxsackievirus B3(CVB3) Hand foot and mouth disease(HFMD) Animal models Syrian hamster Rhesus monkey