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Development and validation of prognostic nomogram based on log odds of positive lymph nodes for patients with gastric signet ring cell carcinoma

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Chinese Journal of Cancer Research 2020年第6期32卷 778-793页

作者： Zijie xu Jing Jing Guiliang Ma Department of General Surgery Qingdao Municipal HospitalQingdao UniversityQingdao 266071China Department of Endocrinology Qingdao Municipal HospitalQingdao UniversityQingdao 266071China

Objective: Our aims were to establish novel nomogram models, which directly targeted patients with signet ring cell carcinoma(SRC), for individualized prediction of overall survival(OS) rate and cancer-specific survival(CSS).Methods: We selected 1,365 SRC patients diagnosed from 2010 to 2015 from Surveillance, Epidemiology and End Results(SEER) database, and then randomly partitioned them into a training cohort and a validation cohort.Independent predicted indicators, which were identified by using univariate testing and multivariate analyses, were used to construct our prognostic nomogram models. Three methods, Harrell concordance index(C-index), receiver operating characteristics(ROC) curve and calibration curve, were used to assess the ability of discrimination and predictive accuracy. Integrated discrimination improvement(IDI), net reclassification improvement(NRI) and decision curve analysis(DCA) were used to assess clinical utility of our nomogram models.Results: Six independent predicted indicators, age, race, log odds of positive lymph nodes(LODDS), T stage, M stage and tumor size, were associated with OS rate. Nevertheless, only five independent predicted indicators were associated with CSS except race. The developed nomograms based on those independent predicted factors showed reliable discrimination. C-index of our nomogram for OS and CSS was 0.760 and 0.763, which were higher than American Joint Committee on Cancer(AJCC) 8 th edition tumor-node-metastasis(TNM) staging system(0.734 and 0.741, respectively). C-index of validation cohort for OS was 0.757 and for CSS was 0.773. The calibration curves also performed good consistency. IDI, NRI and DCA showed the nomograms for both OS and CSS had a comparable clinical utility than the TNM staging system.Conclusions: The novel nomogram models based on LODDS provided satisfying predictive ability of SRC both in OS and CSS than AJCC 8 th edition TNM staging system alone.

关键词： Log odds of positive lymph nodes nomograms prognosis signet ring cell

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Miniaturized retractable thin-film sensor for wearable multifunctional respiratory monitoring

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Nano Research 2023年第9期16卷 11846-11854页

作者： Chengyu Li Zijie xu Shuxing xu Tingyu Wang Siyu Zhou Zhuoran Sun Zhong Lin Wang Wei Tang Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of SciencesBeijing 101400China School of Nanoscience and Technology University of Chinese Academy of SciencesBeijing 100049China Center on Nanoenergy Research School of Physical Science and TechnologyGuangxi UniversityNanning 530004China Peking University Third Hospital Beijing 100191China Georgia Institute of Technology AtlantaGA 30332USA

As extremely important physiological indicators,respiratory signals can often reflect or predict the depth and urgency of various diseases.However,designing a wearable respiratory monitoring system with convenience,excellent durability,and high precision is still an urgent challenge.Here,we designed an easy-fabricate,lightweight,and badge reel-like retractable selfpowered sensor(RSPS)with high precision,sensitivity,and durability for continuous detection of important indicators such as respiratory rate,apnea,and respiratory ventilation.By using three groups of interdigital electrode structures with phase differences,combined with flexible printed circuit boards(FPCBs)processing technology,a miniature rotating thin-film triboelectric nanogenerator(RTF-TENG)was developed.Based on discrete sensing technology,the RSPS has a sensing resolution of 0.13 mm,sensitivity of 7 P·mm^(−1),and durability more than 1 million stretching cycles,with low hysteresis and excellent anti-environmental interference ability.Additionally,to demonstrate its wearability,real-time,and convenience of respiratory monitoring,a multifunctional wearable respiratory monitoring system(MWRMS)was designed.The MWRMS demonstrated in this study is expected to provide a new and practical strategy and technology for daily human respiratory monitoring and clinical diagnosis.

关键词： respiratory monitoring thin-film sensors discrete and vector self-powered triboelectric nanogenerator

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Resource allocation for sum-rate maximization in NOMA-based generalized spatial modulation

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Digital Communications and Networks 2022年第6期8卷 1077-1084页

作者： Guoquan Li zijie Hong Yu Pang Yongjun xu Zhengwen Huang School of Communication and Information Engineering Chongqing University of Posts and TelecommunicationsChongqing400065China Chongqing Key Laboratory of Photoelectronic Information Sensing and Transmitting Technology Chongqing400065China Department of Electronic and Electrical Engineering Brunel University LondonLondonUB8-3PHUK

The Multiple-Input Multiple-Output(MIMO)Non-Orthogonal Multiple Access(NOMA)based on Spatial Modulation(SM-MIMO-NOMA)system has been proposed to achieve better spectral efficiency with reduced radio frequency chains comparing to the traditional MIMO-NOMA system.To improve the performance of SM-MIMO-NOMA systems,we extend them to generalized spatial modulation scenarios while maintaining moderate complexity and fairness.In this paper,system spectral efficiency and transmission quality improvements are proposed by investigating a sum-rate maximization resource allocation problem that is subject to the total transmitted power,user grouping,and resource block constraints.To solve this non-convex and difficult problem,a graph-based user grouping strategy is proposed initially to maximize the mutual gains of intragroup users.An auxiliary-variable approach is then adopted to transform the power allocation subproblem into a convex one.Simulation results demonstrate that the proposed algorithm has better performance in terms of bit error rate and sum rates.

关键词： Resource allocati on NOMA Spatial modulati on Power allocation User grouping

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Enhanced interfacial polarization of defective porous carbon confined CoP nanoparticles forming Mott-Schottky heterojunction for efficient electromagnetic wave absorption

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Nano Research 2023年第3期16卷 4160-4169页

作者： Baojun Wang Fangzhi Huang Hao Wu Zijie xu Shipeng Wang Qinghua Han Fenghua Liu Shikuo Li Hui Zhang School of Materials Science and Engineering Anhui UniversityHefei 230601China School of Chemistry and Chemical Engineering Anhui UniversityHefei 230601China Ningbo Institute of Materials Technology and Engineering Chinese Academy of ScienceNingbo 315201China Key Laboratory of Structure and Functional Regulation of Hybrid Materials(Anhui University) Ministry of EducationHefei 230601China

Integrating heterogeneous interface through nanostructure design and interfacial modification is essential to realize strengthened interfacial polarization relaxation in electromagnetic wave absorption.However,an in-depth comprehension of the interfacial polarization behavior at hetero-junction/interface is highly desired but remains a great challenge.Herein,a Mott-Schottky heterojunction consisting of honeycomb-like porous N-doped carbon confined CoP nanoparticles(CoP@HNC)is designed to elevate the interfacial polarization strength.Simultaneously,corresponding electron migration and redistribution between the heterointerface of defective carbon and CoP nanoparticles are revealed.The significant difference in the work function on both sides of heterogeneous interface boosts the interfacial polarization in high frequency region.Furthermore,the relevant spectroscopic characterizations demonstrate that electron spontaneously migrates from CoP to N-doped carbon at the heterointerface,thereby contributing to the accumulation of electron on defective carbon side and the distribution of hole on CoP side.Impressively,benefitting from the synergistic effects of three-dimensional porous conductive carbon skeleton,foreign N heteroatoms,special CoP nanoparticles,and the resultant CoP/N-doped carbon Mott-Schottky heterojunction,the CoP@HNC exhibits remarkable electromagnetic wave absorption performances with minimum reflection loss up to−60.8 dB and the maximum effective absorption bandwidth of 4.96 GHz,which is superior to most of recently reported transition metal phosphides microwave absorbing composites.The present work opens a new avenue for designing heterogeneous interface to realize strengthened microwave absorption capability and also reveals the in-depth influence of interface structure on electromagnetic wave absorption.

关键词： honeycomb-like structure Mott-Schottky heterojunction interfacial polarization electron transfer microwave absorption

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Phase Noise Pre-correction Scheme for SC-FDMA Signals in LTE-Uplink

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Chinese Journal of Electronics 2017年第3期26卷 634-639页

作者： xu zijie REN Guangliang ZHANG Yang State Key Laboratory of Integrated Service Networks Xidian University National Mobile Communications Research Laboratory Southeast University

This paper proposes a novel carrier Phase noise(PN)pre-correction scheme with an adaptive PN prediction algorithm for Single-carrier Frequency-division multiple-access(SC-FDMA)systems to alleviate degradation due to the PN.Our proposed PN prediction algorithm is a modified polynomial fitting algorithm which is based on receding horizon principle.The parameters of the prediction model are optimized by using the algorithm on PN samples of the local oscillator signal in a training window.By using the optimized prediction model parameters and the latest PN samples,we can predict future PN samples.Then these predicted PN samples are put into our proposed PN pre-correction scheme and the SC-FDMA symbols at the transmitter are pre-compensated.Due to the absence of the radio frequency delay device,the proposed scheme has a low hardware complexity.Simulation results show that our proposed scheme can greatly reduce the effect of the PN on the transmitted SC-FDMA signal.

关键词： Phase noise(PN) Single-carrier Frequency-division multiple access(SC-FDMA) Prediction algorithm

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Diets enriched with finely ground wheat bran alter digesta passage rate and composition of the gut microbiome in sows

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Animal Nutrition 2023年第1期12卷 32-41页

作者： zijie Wang Wenhui Wang Song xu Jian Ding Xiangfang Zeng Hu Liu Fenglai Wang State Key Lab of Animal Nutrition College of Animal Science&TechnologyChina Agricultural UniversityBeijing 100193China National Animal Husbandry Service Ministry of Agriculture and Rural Affairs of the People's Republic of ChinaBeijing 100000China

We investigated the effects of finely ground wheat bran on the nutrient digestibility, digesta passage rate,and gut microbiota structure in sows. A 3 × 3 Latin square design with 3 test periods and 3 experimental diets was used. Six non-pregnant sows(parity: 5 to 7) were randomly assigned to 3 experimental diets with 2 replicates per treatment in each period. Each period lasted 19 d(12 d for adaptation and 7 d for experiment). The experimental diets included(a) a basal corn and soybean meal diet(CON),(b) a basal diet with 20% coarse wheat bran(CWB;particle size: 605 μm), and(c) a basal diet with 20% fine wheat bran(FWB;particle size: 438 μm). The results demonstrated that the apparent total tract digestibility of neutral detergent fiber, acid detergent fiber and energy were reduced(P < 0.05) in the FWB and CWB groups compared with those in the CON group. Viscosity of digesta increased(P < 0.001) in FWB-fed sows. The passage rate of digesta from the mouth to the ileum decreased(P < 0.001) in FWB-fed sows. Peptide YY(PYY) concentration increased(P = 0.01) in FWB-fed sows after 30 min of feeding.In the FWB group, the relative abundance of Lactobacillaceae at the family level increased(P < 0.05) in the ileal digesta. At the class level, the relative abundance of Clostridia in feces decreased(P < 0.05) in FWB-fed sows. FWB enhanced the concentration of butyrate in feces compared with CON and CWB(P = 0.04). These results suggest that dietary supplementation with finely ground wheat bran reduces the passage rate of digesta, increases the abundance of beneficial microorganisms, and elevates the concentration of short-chain fatty acids and PYY in sows. These findings indicate that the addition of finelyground wheat bran to the diets of sows is more effective than using coarse wheat bran for improving their satiety and intestinal microbial composition.

关键词： Finely ground wheat bran Digestive physiology Digesta passage rate Gut microbiota Sow

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Promoting the microwave absorption performance of hierarchical CF@NiO/Ni composites via phase and morphology evolution

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International Journal of Minerals,Metallurgy and Materials 2023年第3期30卷 494-503页

作者： Shipeng Wang Ziyan Liu Qiangchun Liu Baojun Wang Wei Wei Hao Wu Zijie xu Shikuo Li Fangzhi Huang Hui Zhang School of Materials Science and Engineering Anhui UniversityHefei 230601China Key Laboratory of Structure and Functional Regulation of Hybrid Materials Ministry of EducationAnhui UniversityHefei 230601China School of Chemistry and Chemical Engineering Anhui UniversityHefei 230601China School of Physics and Electronic Information Huaibei Normal UniversityHuaibei 235000Chin

Lightweight and efficient carbon-based microwave absorbents are significant in addressing the increasing severity of electromagnetic pollution.In this study,hierarchical NiO/Ni nanosheets with a tuneable phase and morphology supported on a carbon fiber substrate(CF@NiO/Ni)were fabricated using a hydrothermal approach and post-annealing treatment.As the annealing temperature increases,more metallic Ni is formed,and an apparent porosity appears on the sheet surface.Benefiting from the advantages of a three-dimensional(3D)conducting network,hierarchical porous structure,reinforced dipole/interface polarization,multiple scattering,and good impedance matching,the CF@NiO/Ni-500 composite exhibits an excellent microwave absorption performance even at a filling rate of only 3wt%.Specifically,its minimal reflection loss is-43.92 dB,and the qualified bandwidth is up to 5.64 GHz.In addition,the low radar cross-section area of the CF@NiO/Ni composite coating confirms its strong ability to suppress electromagnetic wave scattering.We expect that this work could contribute to a deeper understanding of the phase and morphology evolution in enhancing microwave absorption.

关键词： carbon fiber nickel nickel oxide interfacial polarization microwave absorption

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早期中国共产党人对“半殖民地”“半封建”话语的接受与使用——兼论其对中共实行“党内合作”的影响

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苏区研究 2023年第6期 86-97页

作者：徐子杰华中师范大学中国近代史研究所湖北武汉430079

列宁最早使用“半殖民地”“半封建”的话语来定义中国国情。列宁认为,在帝国主义势力与旧有封建制度的影响下,民国初期的中国国情既是“半殖民地半独立”和“半殖民地半自决”的,也是“半封建半资本主义”和“半封建半民主共和”的。... 详细信息

列宁最早使用“半殖民地”“半封建”的话语来定义中国国情。列宁认为,在帝国主义势力与旧有封建制度的影响下,民国初期的中国国情既是“半殖民地半独立”和“半殖民地半自决”的,也是“半封建半资本主义”和“半封建半民主共和”的。而他并不看好这一状况下各种进步因素的增长。以陈独秀、蔡和森为代表的早期中国共产党人继承并发展列宁的观点,对中国近代以来国情问题的认识逐渐走向深入。他们不仅开始使用“半殖民地”“半封建”的话语来对其予以分析,而且随之提出了对中共革命战略的相应调整。从建党之初在国内独立自主开展无产阶级革命,到“三大”决定与国民党通过“党内合作”方式进行国民革命,中共在较短时间内实现了革命战略的重大转变。在这一变动过程中,早期中国共产党人对“半殖民地”“半封建”话语的构建和传播起到了明显推动作用。

关键词：早期中国共产党人 “半殖民地” “半封建” 列宁 “党内合作”

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A CNN-SVR model for NO_(2)profile prediction based on MAX-DOAS observations:The influence of Chinese New Year overlapping the 2020 COVID-19 lockdown on vertical distributions of tropospheric NO_(2)in Nanjing,China

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Journal of Environmental Sciences 2024年第7期141卷 151-165页

作者： Xin Tian zijie Wang Pinhua Xie Jin xu Ang Li Yifeng Pan Feng Hu Zhaokun Hu Mingsheng Chen Jiangyi Zheng Information Materials and Intelligent Sensing Laboratory of Anhui Province Institutes of Physical Science and Information TechnologyAnhui UniversityHefei 230601China Key laboratory of Environmental Optical and Technology Anhui Institute of optics and Fine MechanicsHefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031China School of Environmental Science and Optoelectronic Technology University of Science and Technology of ChinaHefei 230026China

In this study,a hybrid model,the convolutional neural network-support vector regression model,was adopted to achieve prediction of the NO_(2)profile in Nanjing from January 2019to March 2021.Given the sudden decline in NO_(2)in February 2020,the contribution of the Coronavirus Disease-19(COVID-19)lockdown,Chinese New Year(CNY),and meteorologi cal conditions to the reduction of NO_(2)was evaluated.NO_(2)vertical column densities(VCDs) from January to March 2020 decreased by 59.05%and 32.81%,relative to the same period in 2019 and 2021,respectively.During the period of 2020 COVID-19,the average NO_(2)VCDs were 50.50%and 29.96%lower than those during the pre-lockdown and post-lockdown pe riods,respectively.The NO_(2)volume mixing ratios(VMRs)during the 2020 COVID-19 lock down significantly decreased below 400 m.The NO_(2)VMRs under the different wind fields were significantly lower during the lockdown period than during the pre-lockdown period This phenomenon could be attributed to the 2020 COVID-19 lockdown.The NO_(2)VMRs be fore and after the CNY were significantly lower in 2020 than in 2019 and 2021 in the same period,which further proves that the decrease in NO_(2)in February 2020 was attributed to the COVID-19 lockdown.Pollution source analysis of an NO_(2)pollution episode during the lockdown period showed that the polluted air mass in the Beijing-Tianjin-Hebei was trans ported southwards under the action of the north wind,and the subsequent unfavorable meteorological conditions(local wind speed of<2.0 m/sec)resulted in the accumulation o pollutants.

关键词： MAX-DOAS CNN-SVR Nitrogen dioxide COVID-19 Chinese New Year Regional transport

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Self-Assembly 3D Porous Crumpled MXene Spheres as Efficient Gas and Pressure Sensing Material for Transient All-MXene Sensors

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Nano-Micro Letters 2022年第4期14卷 1-14页

作者： zijie Yang Siyuan Lv Yueying Zhang Jing Wang Li Jiang Xiaoteng Jia Chenguang Wang xu Yan Peng Sun Yu Duan Fangmeng Liu Geyu Lu State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin University2699 Qianjin StreetChangchun 130012People’s Republic of China School of Electronic and Information Engineering Changchun University of Science and TechnologyChangchun 130022People’s Republic of China

Environmentally friendly degradable sensors with both hazardous gases and pressure efficient sensing capabilities are highly desired for various promising applications,including environmental pollution monitoring/prevention,wisdom medical,wearable smart devices,and artificial intelligence.However,the transient gas and pressure sensors based on only identical sensing material that concurrently meets the above detection needs have not been reported.Here,we present transient all-MXene NO_(2) and pressure sensors employing three-dimensional porous crumpled MXene spheres prepared by ultrasonic spray pyrolysis technology as the sensing layer,accompanied with water-soluble polyvinyl alcohol substrates embedded with patterned MXene electrodes.The gas sensor achieves a ppb-level of highly selective NO_(2) sensing,with a response of up to 12.11%at 5 ppm NO_(2) and a detection range of 50 ppb-5 ppm,while the pressure sensor has an extremely wide linear pressure detection range of 0.14-22.22 kPa and fast response time of 34 ms.In parallel,all-MXene NO_(2) and pressure sensors can be rapidly degraded in medical H_(2)O_(2) within 6 h.This work provides a new avenue toward environmental monitoring,human physiological signal monitoring,and recyclable transient electronics.

关键词： All-MXene 3D porous crumpled MXene sphere Transient NO2 and pressure sensor

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