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数字时代GPT技术对中国舞蹈教育的影响探析

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艺术科技 2024年第9期37卷 229-231,246页

作者：李紫键莫斯科国立文化学院俄罗斯莫斯科141406

目的:文章旨在探讨人工智能技术的重要突破——GPT系统(Generative Pre-trained Transformer)对中国舞蹈教育领域产生的影响,分析GPT系统在中国舞蹈教育中的潜在作用,探讨其如何改进教学方法,优化学生的学习体验,并促进中国舞蹈传统的... 详细信息

目的:文章旨在探讨人工智能技术的重要突破——GPT系统(Generative Pre-trained Transformer)对中国舞蹈教育领域产生的影响,分析GPT系统在中国舞蹈教育中的潜在作用,探讨其如何改进教学方法,优化学生的学习体验,并促进中国舞蹈传统的传承。同时揭示GPT技术应用于舞蹈教育中面临的挑战和问题。方法:文章采用文献综述、案例分析等方法。首先对GPT系统的基本原理和应用领域进行详细的文献综述,以理解其功能和潜力。然后通过案例分析,深入探讨GPT系统在中国舞蹈教育中的实际应用,重点关注个性化教学、创意激发和舞蹈传承等方面。结果:研究表明,GPT系统在中国舞蹈教育中具有巨大的应用潜力。采取个性化教学手段,GPT可以根据学生的需求和水平提供个性化的学习材料,从而提高学习效率。此外,GPT的创意生成功能可以激发学生的创造力和想象力,促进他们在舞蹈领域的创新。同时,GPT还可以用于记录和传承中国传统舞蹈,以促进这一珍贵文化遗产的传承和弘扬。结论:GPT系统对中国舞蹈教育领域具有重要的影响。然而,也必须谨慎应对技术应用中的挑战,如平衡人机关系和隐私保护。最终,在中国舞蹈教育中高效应用GPT技术需要技术与教育者的紧密合作,以确保学生能够充分受益于这一创新,同时保护他们的权益和隐私。通过深入挖掘GPT系统的潜力,中国舞蹈教育将迎来更繁荣的未来,同时促进中国传统舞蹈的保护与传承。

关键词： GPT系统中国舞蹈教育个性化教学数字时代技术应用挑战

酿酒酵母对浓香型白酒酒醅微生物群落结构及功能的影响

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中国食品学报 2024年第2期24卷 71-82页

作者：马世源李子健罗惠波孙跃鹏李津黄丹四川轻化工大学生物工程学院四川自贡643000 酿酒生物技术及应用四川省重点实验室四川自贡643000 宜宾今良造制酒有限公司四川宜宾644000

通过分析酿酒酵母对浓香型白酒酒醅微生物组成及挥发性代谢物的影响,探究其对酒醅微生物生态网络、挥发性代谢物以及微生物群落代谢功能的作用。将1株分离自浓香型白酒酒醅的酿酒酵母(Y1)扰动酒醅固态发酵过程,采用高通量测序技术和顶... 详细信息

通过分析酿酒酵母对浓香型白酒酒醅微生物组成及挥发性代谢物的影响,探究其对酒醅微生物生态网络、挥发性代谢物以及微生物群落代谢功能的作用。将1株分离自浓香型白酒酒醅的酿酒酵母(Y1)扰动酒醅固态发酵过程,采用高通量测序技术和顶空固相微萃取质谱联用技术分析微生物群落构成和挥发性代谢物组成,利用随机森林学习算法计算能够表征试验组与空白组间差异的生物标志物,基于共现性网络模型分析试验组与空白组的微生物生态网络差异,采用PLS-DA和斯皮尔曼相关性分别分析其挥发性风味物质差异、差异代谢物与生物标志物的相关性,最后通过PICRUST2功能预测以及通路富集分析微生物群落潜在功能的改变。结果表明,5种细菌和15种真菌可以作为表征酿酒酵母扰动酒醅中微生物组成的生物标志物,并且提高了微生物生态网络的复杂性;挥发性代谢物的组成发生了改变,共有18种差异代谢物,部分挥发性代谢物的含量得到提高,绝大多数生物标志物与差异代谢呈显著相关。此外,酿酒酵母的扰动效应导致微生物群落出现180个上调基因,46个下调基因,这些基因大多数与物质的代谢有关。这些结果为酿酒酵母在白酒发酵中的应用及优化酒醅发酵过程提供了试验依据。

关键词：酒醅酿酒酵母共现性网络生物扰动挥发性代谢物功能预测

Letter to the editor: Anti-RAS drugs and SARS-Co V-2 infection

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Acta Pharmaceutica Sinica B 2020年第7期10卷 1251-1252页

作者： Jingwei Bian Rongsheng Zhao Suodi Zhai zijian li Department of Pharmacy Peking University Third HospitalBeijing 100083China Department of Cardiology and Institute of Vascular Medicine Peking University Third HospitalKey Laboratory of Cardiovascular Molecular Biology and Regulatory PeptidesMinistry of HealthKey Laboratory of Molecular Cardiovascular SciencesMinistry of EducationBeijing Key Laboratory of Cardiovascular Receptors ResearchBeijing 100083China

To the Editor:Coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-Co V-2)has spread rapidly throughout the world.It has already posed a great threat to global public health... 详细信息

关键词： ACE2 drugs SARS

Influence of chamber structure on arc quenching in multigap system

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High Voltage 2020年第3期5卷 313-318页

作者： zijian li Jufeng Wang Xin Zhou Shangshi Huang Renbao Yan Zhijian Xia School of Electrical Engineering Guangxi UniversityNanningPeople's Republic of China Meishan Power Supply Branch of State Grid Sichuan Electric Power Co. LtdSichuanPeople's Republic of China Fuzhou Power Supply Branch of State Grid Jiangxi Electric Power Co. LtdJiangxiPeople's Republic of China

In order to improve the arc quenching ability of the multigap system,it is important to know the principle of arc quenching and how the chamber structure affects the arc development process in the multigap system.In this study,the twodimensional geometric model of the multigap system is established based on the magnetohydrodynamics theory in COMSOL multiphysics simulation platform.The principle of arc quenching in the multigap system is explained in detail by analysing the physical characteristics of the arc in the multigap system.The simulation result shows that the arc is compressed at large scales in the semi-closed chambers of the multigap system,which results in an instantaneous temperature rise of the arc,thus,forming the self-expanding airflow.The strong self-expanding airflow cuts off the arc channel and blocks the energy supply of the arc.The influence of the chamber structure on arc quenching in the multigap system is manifested in the fact that proper improvement of the width and depth of the chamber subserves arc cooling,the reduction of the deflection angle and the increment of the number of the chambers are conductive to arc extinction.

关键词： quenching system structure

Pathological matrix stiffness promotes cardiac fibroblast differentiation through the POU2F1 signaling pathway

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Science China(life Sciences) 2021年第2期64卷 242-254页

作者： Mingzhe li Jimin Wu Guomin Hu Yao Song Jing Shen Junzhou Xin zijian li Wei liu Erdan Dong Ming Xu Youyi Zhang Han Xiao Department of Cardiology and Institute of Vascular Medicine Peking University Third Hospital/NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides/Key Laboratory of Molecular Cardiovascular ScienceMinistry of Education/Beijing Key Laboratory of Cardiovascular Receptors ResearchBeijing 100191China Division of Cardiovascular Sciences Faculty of Biology Medicine and HealthUniversity of ManchesterManchester M139PTUK Institute of Cardiovascular Sciences Health Science CenterPeking UniversityBeijing 100191China

Cardiac fibroblast(CF)differentiation into myofibroblasts is a crucial cause of cardiac fibrosis,which increases in the extracellular matrix(ECM)stiffness.The increased stiffness further promotes CF differentiation and fibrosis.However,the molecular mechanism is still unclear.We used bioinformatics analysis to find new candidates that regulate the genes involved in stiffnessinduced CF differentiation,and found that there were binding sites for the POU-domain transcription factor,POU2F1(also known as Oct-1),in the promoters of 50 differentially expressed genes(DEGs)in CFs on the stiffer substrate.Immunofluorescent staining and Western blotting revealed that pathological stiffness upregulated POU2F1 expression and increased CF differentiation on polyacrylamide hydrogel substrates and in mouse myocardial infarction tissue.A chromatin immunoprecipitation assay showed that POU2F1 bound to the promoters of fibrosis repressors IL1R2,CD69,and TGIF2.The expression of these fibrosis repressors was inhibited on pathological substrate stiffness.Knockdown of POU2F1 upregulated these repressors and attenuated CF differentiation on pathological substrate stiffness(35 kPa).Whereas,overexpression of POU2F1 downregulated these repressors and enhanced CF differentiation.In conclusion,pathological stiffness upregulates the transcription factor POU2F1 to promote CF differentiation by inhibiting fibrosis repressors.Our work elucidated the crosstalk between CF differentiation and the ECM and provided a potential target for cardiac fibrosis treatment.

关键词： fibroblast differentiation matrix stiffness POU2F1 cardiac fibrosis transcription factor

弹−塑性基础边界两侧采空(留煤柱)基本顶板结构初次破断特征

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煤炭学报 2024年第5期49卷 2195-2211页

作者：陈冬冬李子健谢生荣何富连罗昱蒋再胜马翔李辉中国矿业大学(北京)能源与矿业学院北京100083

为了研究两侧采空留煤柱工程条件下基本顶板结构的断裂位态及工程指导意义,构建考虑实体煤弹塑性变形与两侧煤柱宽度及支撑能力弱化的基本顶板结构双塑化基础边界力学模型,基于有限差分算法与主弯矩破断准则系统计算了在非对称煤柱区和... 详细信息

为了研究两侧采空留煤柱工程条件下基本顶板结构的断裂位态及工程指导意义,构建考虑实体煤弹塑性变形与两侧煤柱宽度及支撑能力弱化的基本顶板结构双塑化基础边界力学模型,基于有限差分算法与主弯矩破断准则系统计算了在非对称煤柱区和长边实体煤区的断裂线形态、区位属性及整体位态特征,并从7个层面、横纵向4对区域与传统模型对比,阐明新模型所得新结论及工程意义。结论如下:(1)两侧非对称煤柱参数对长边实体煤区域的基本顶主弯矩及破断位置影响小,但分别显著影响煤柱区的主弯矩大小、位置及断裂形态。两侧煤柱区(较强/宽煤柱区+较弱/窄煤柱区)基本顶断裂线形态有3类演化模式,随基本顶厚度及弹模增大而煤柱宽度、支撑能力及悬顶跨度减小,其变化规律为:非对称的“连续单弧形+连续单弧形”→“连续单弧形+开口间断双短弧形”→非对称的“开口间断双短弧形+开口间断双短弧形”。(2)长边实体煤区基本顶的断裂线主要有3类区位属性,随基本顶厚度及弹模增大而实体煤的塑性区宽度、塑化程度及悬顶跨度减小,其演变规律为:断裂线在塑性煤体区(C-S式)→弹塑性煤体分界区(C-TS式)→弹性煤体区(C-T式);(3)考虑断裂线区位属性,随基本顶厚度和弹模增大而煤柱宽度、支撑能力及悬顶跨度减小的基本顶全区域破断模式及演变规律为:C-S式的■→C-TS式的■→C-T式的■→C-T式的■→C-T式的■。针对研究两侧采空(煤柱)基本顶板结构破断的3类力学模型,从7个层面对比了3类模型的重要区别,从横向4个区域(开采区域的前方与后方、两侧煤柱区)与纵向4个区域(非对称遗留煤柱下伏、下伏开采空间出/进煤柱/体)阐明了其重要工程作用。

关键词：遗留煤柱基本顶两侧采空弹−塑性基础板结构

Practical decoy-state quantum secure direct communication

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Science China(Physics,Mechanics & Astronomy) 2021年第12期64卷 68-75页

作者： Xin liu zijian li Di Luo Chunfeng Huang Di Ma Minming Geng Junwei Wang Zhenrong Zhang Kejin Wei Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China Guangxi Key Laboratory of Multimedia Communications and Network Technology School of ComputerElectronicsand InformationGuangxi UniversityNanning 530004China CAS Quantum Network Co. LtdShanghai 201315China

Quantum secure direct communication(QSDC) has been demonstrated in both fiber-based and free-space channels using attenuated lasers. Decoy-state QSDC by exploiting four decoy states has been proposed to address the problem of photon-numbersplitting attacks caused by the use of attenuated lasers. In this study, we present an analysis of the practical aspects of decoy-state QSDC. First, we design a two-decoy-state protocol that only requires two decoy states, thereby significantly reducing experimental complexity. Second, we successfully perform full parameter optimization for a real-life QSDC system by introducing a genetic algorithm. Our simulation results show that the two-decoy-state protocol could be the best choice for developing a practical QSDC system. Furthermore, full optimization is crucial for a high-performance QSDC system. Our work serves as a major step toward the further development of practical decoy-state QSDC systems.

关键词： quantum secure direct communication decoy-state method full parameter optimization

Single-molecule imaging reveals the stoichiometry change of epidermal growth factor receptor during transactivation by β_2-adrenergic receptor

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Science China Chemistry 2017年第10期60卷 1310-1317页

作者： Mingliang Zhang Kangmin He Jimin Wu Nan li Jinghe Yuan Wei Zhou Zi Ye zijian li Han Xiao Zhizhen Lv Youyi Zhang Xiaohong Fang Institute of Vascular Medicine of Third Hospital Ministry of Health Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides Beijing Key Laboratory of Cardiovascular Receptors and Academy for Advanced Interdisciplinary Studies Peking University Beijing National Laboratory for Molecular Sciences Key Laboratory of Molecular Nanostructures and Nanotechnology Institute of ChemistryChinese Academy of Sciences

Stimulation of G protein-coupled receptors(GPCRs) can lead to the transactivation of the epidermal growth factor receptors(EGFR). The cross-communication between the two signaling pathways regulates several important physiological or pathological processes. However, the molecule mechanism underlying EGFR transactivation remains poorly understood. Here, we aim to study the GPCR-mediated EGFR transactivation process using the single-molecule fluorescence imaging and tracking approach.We found that although EGFR existed as monomers at the plasma membrane of resting cells, they became dimers and thus diffused slower following the activation of β2-adrenergic receptor(β2-AR) by isoproterenol(ISO). We further proved thatβ2-AR-mediated changes of EGFR in stoichiometry and dynamics were mediated by Src kinase. Thus, the observations obtained via the single-molecule imaging and tracking methods shed new insights into the molecular mechanism of EGFR transactivation at single molecule level.

关键词：表皮生长因子受体单分子成像化学计量学转录 β2-肾上腺素能受体 G蛋白偶联受体 EGFR 显示

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基于因果机制约束的强化推荐系统

计算机工程 2024年第5期50卷 279-290页

作者：张斯力李梓健蔡瑞初郝志峰闫玉光广东工业大学计算机学院广东广州510006 汕头大学工学院广东汕头515063

利用历史数据训练强化学习推荐系统已经得到越来越多研究人员的关注,但是历史数据使得强化学习模型对状态-动作估值错误,产生数据偏差,如流行度偏差和选择偏差。造成上述问题的原因是历史数据分布与强化学习策略采集的数据分布不一致以... 详细信息

利用历史数据训练强化学习推荐系统已经得到越来越多研究人员的关注,但是历史数据使得强化学习模型对状态-动作估值错误,产生数据偏差,如流行度偏差和选择偏差。造成上述问题的原因是历史数据分布与强化学习策略采集的数据分布不一致以及历史数据本身带有偏差。使用因果机制可以在约束策略采集数据分布的同时解决数据偏差的问题,提出基于因果机制约束的强化推荐系统,包含因果机制约束模块和对比策略模块。因果机制约束模块用于约束推荐策略可选择的样本空间以减少策略分布与数据分布误差,考虑随时间动态变化的物品流行度分布以缓解流行度偏差。对比策略模块通过平衡正负样本的重要性,缓解选择偏差的影响。在真实数据集Ciao和Epinions上的实验结果表明,相比深度Q网络(DQN)-r、GAIL、SOFA等,该算法具有较优的准确性和多样性,包含加入因果机制约束模块后的模型在F-measure指标上分别提高2%和3%,进一步验证了因果机制约束模块的有效性。

关键词：推荐系统强化学习因果机制外推误差数据偏差