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A survey on intelligence approaches that may be useful for information and communication technology research

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The Journal of China Universities of Posts and Telecommunications 2008年第1期15卷 1-5,17页

作者： zhong yi-xin School of Information Engineering Beijing University of Posts and Telecommunications Beijing 100876 China

The concepts on information and communication technology （ICT） and ＂intelligence＂ are defined firstly and the analyses on the environment and requirements for ICT are then followed. Based on the definitions and the analyses, a survey on intelligence approaches that may be useful for ICT is thus made. The conclusion drawn from the survey is a recommendation by saying that intelligence approaches have been one of the keys for further development of the entirety of ICT and therefore should receive much more attentions from ICT researchers in the years to come.

关键词： uncertainty complexity intelligence approaches,ICT

血清LRG1及FGF-21水平与新生血管性青光眼的相关性

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国际眼科杂志 2025年第1期25卷 118-121页

作者：罗忠周鹤黄怡董万江绵阳万江眼科医院四川省绵阳市621000

目的:探讨血清富亮氨酸α-2糖蛋白1(LRG1)、成纤维细胞生长因子21(FGF-21)水平与新生血管性青光眼(NVG)的相关性。方法:选取2020-09/2022-09本院眼科收治的110例110眼NVG患者为NVG组(Ⅱ级23例、Ⅲ级44例、Ⅳ级43例),性别、年龄相匹配的... 详细信息

目的:探讨血清富亮氨酸α-2糖蛋白1(LRG1)、成纤维细胞生长因子21(FGF-21)水平与新生血管性青光眼(NVG)的相关性。方法:选取2020-09/2022-09本院眼科收治的110例110眼NVG患者为NVG组(Ⅱ级23例、Ⅲ级44例、Ⅳ级43例),性别、年龄相匹配的白内障患者90例90眼为对照组。ELISA检测血清中LRG1、FGF-21、血管内皮生长因子(VEGF)、色素上皮衍生因子(PEDF)及肿瘤坏死因子-α(TNF-α)水平;Pearson相关性分析血清LRG1、FGF-21水平与Teich分级、VEGF、PEDF、TNF-α水平的相关性。结果:NVG组与对照组相比,血清LRG1、FGF-21、VEGF、PEDF、TNF-α水平显著升高(均P<0.01)。随着Teich分级的增加,NVG患者血清LRG1、FGF-21、VEGF、PEDF、TNF-α水平依次显著升高(均P<0.05)。NVG患者血清中LRG1、FGF-21水平与VEGF、PEDF、TNF-α水平呈正相关(均P<0.05)。结论:NVG患者血清LRG1、FGF-21水平显著升高,与VEGF、PEDF及TNF-α水平正相关,二者可能与NVG的发生有关。

关键词：新生血管性青光眼富亮氨酸α-2糖蛋白1(LRG1) 成纤维细胞生长因子21(FGF-21) Teich分级相关性

Dynamic development of microglia and macrophages after spinal cord injury

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Neural Regeneration Research 2025年第12期20卷 3606-3619页

作者： Hu-Yao Zhou Xia Wang yi Li Duan Wang Xuan-zi Zhou Nong Xiao Guo-Xing Li Gang Li Institute of Life Sciences Chongqing Medical UniversityChongqingChina Department of Rehabilitation Children’s Hospital of Chongqing Medical UniversityNational Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChongqing Key Laboratory of Translational Medical Research in Cognitive Development and Learning and Memory DisordersChongqingChina Molecular Medicine Diagnostic and Testing Center Chongqing Medical UniversityChongqingChina

Secondary injury following spinal cord injury is primarily characterized by a complex inflammatory response,with resident microglia and infiltrating macrophages playing pivotal *** previous studies have grouped these two cell types together based on similarities in structure and function,an increasing number of studies have demonstrated that microglia and macrophages exhibit differences in structure and function and have different effects on disease *** this study,we used single-cell RNA sequencing and spatial transcriptomics to identify the distinct evolutionary paths of microglia and macrophages following spinal cord *** results showed that microglia were activated to a pro-inflammatory phenotype immediately after spinal cord injury,gradually transforming to an anti-inflammatory steady state phenotype as the disease *** macrophages,our findings highlighted abundant communication with other cells,including fibroblasts and *** pro-inflammatory and neuroprotective effects of macrophages were also identified;the pro-inflammatory effect may be related to integrin β2(Itgb2) and the neuroprotective effect may be related to the oncostatin M *** findings were validated by in vivo *** research underscores differences in the cellular dynamics of microglia and macrophages following spinal cord injury,and may offer new perspectives on inflammatory mechanisms and potential therapeutic targets.

关键词： acute inflammation bioinformatics analysis fibroblast integrinβ2 ligand-receptor interaction neuroinflammation oncostatin M single-cell RNA sequencing spatial transcriptomics spinal cord injury

豌豆蚜组织蛋白酶K基因(ApCtsk1)的鉴定及功能研究

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草业学报 2025年第2期34卷 174-183页

作者：马瑞吴宜亭李岩于展姿刘磊王森山甘肃农业大学植物保护学院甘肃兰州730070

为探究豌豆蚜ApCtsk1基因的生理功能,评估其作为豌豆蚜防治靶标的潜力,从而为防控策略的制定提供理论依据。本研究以豌豆蚜为对象,利用NCBI、ExPASy Proteomics Server、MEGA 11等在线网站和软件分析ApCtsk1的氨基酸序列特征并构建系统... 详细信息

为探究豌豆蚜ApCtsk1基因的生理功能,评估其作为豌豆蚜防治靶标的潜力,从而为防控策略的制定提供理论依据。本研究以豌豆蚜为对象,利用NCBI、ExPASy Proteomics Server、MEGA 11等在线网站和软件分析ApCtsk1的氨基酸序列特征并构建系统发育树;采用RT-qPCR技术解析其在不同发育阶段、不同组织的表达模式;通过RNAi研究ApCtsk1在豌豆蚜个体发育和繁殖中的生物学功能。结果表明:豌豆蚜ApCtsk1与半翅目蚜科昆虫的半胱氨酸蛋白酶聚为一支,其在4龄若蚜期显著高表达,并在成虫腹部、卵巢、表皮表达量较高。RNAi干扰3龄若蚜的ApCtsk1后,与对照组相比,豌豆蚜死亡率升高至22.22%,体长体宽分别减小12.56%、13.22%,体色异常,行动缓慢。此外,经dsApCtsk1处理的蚜虫出现蜕皮失败的致死现象,且干扰后豌豆蚜繁殖力也受到影响,表现为产蚜时间的推迟和一段时间产蚜量的降低。由此可见,ApCtsk1在豌豆蚜个体发育、存活和繁殖过程中具有重要的作用。

关键词：豌豆蚜组织蛋白酶K 繁殖 RNAi

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Enhancing self-assembly efficiency of macrocyclic compound into nanotubes by introducing double peptide linkages

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Chinese Chemical Letters 2024年第11期35卷 299-303页

作者： Cheng-Yan Wu yi-Nan Gao zi-Han Zhang Rui Liu Quan Tang zhong-Lin Lu College of Chemistry Beijing Normal UniversityBeijing 100875China College of Chemistry and Materials Engineering Bohai UniversityJinzhou 121013China

Constructing more stable self-assembled organic nanotubes has been one of the focuses of scientists in recent ***(m-phenylene ethynylene)(m-PE)benzene macrocycles can form stable tubular self-assemblies in nonpolar or weakly polar solvents through theπ-πinteraction of the main skeleton and the hydrogen bonding of the side chain *** covalently linked two macrocyclic units at the para position of the macrocycles using two oligo(β-alanine)linkers through an efficient synthetic ***-visible spectroscopy,fluorescence spectroscopy,and circular dichroism spectroscopy were employed to demonstrate that the incorporation of two peptide chains significantly enhances the stability of the ***,the average open time of the ion channel formed by the macrocyclic dimer in the lipid bilayer was significantly better than that of the ion channel formed by a single *** study shows that this strategy effectively improves the efficiency of self-assembly and the stability of its formed self-assemblies,providing a feasible strategy for constructing organic self-assembled nanotubes in highly polar solvents.

关键词： Macrocyclic compounds Supramolecular assembly Ion transportation Synthetic ion channels Molecular nanotubes

流速、pH值、硫酸根和碱度耦合变化对管网铁释放的影响

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中国环境科学 2025年第1期45卷 124-131页

作者：王龙张卉张珊苗梓怡刘卓范明洲贾培馨冯永嘉西安建筑科技大学环境与市政工程学院陕西西安710055

当饮用水水质和水力条件发生变化时,给水管网中管垢和水相之间的固液平衡会被破坏,引起铁释放,造成饮用水的二次污染.本文通过建立动态模拟系统,重点分析了流速(v)、pH值、硫酸根(SO_(4)^(2-))和碱度(Alk)耦合变化影响下的给水管网铁释... 详细信息

当饮用水水质和水力条件发生变化时,给水管网中管垢和水相之间的固液平衡会被破坏,引起铁释放,造成饮用水的二次污染.本文通过建立动态模拟系统,重点分析了流速(v)、pH值、硫酸根(SO_(4)^(2-))和碱度(Alk)耦合变化影响下的给水管网铁释放过程,并运用主成分回归法构建了铁释放预测模型.结果表明,在v=0.12m/s、pH=6.5、C_(SO_(4)^(2-))=250mg/L、Alk=100mg/L CaCO_(3)的条件下,钢管和铸铁管总铁浓度达到最大,分别为1.423mg/L和0.184mg/L;2种管道腐蚀产物中均存在大量片状和散射球状结构,主要成分均为α-FeOOH,且实验后钢管和铸铁管管垢中α-FeOOH、γ-FeOOH和Fe_(2)O_(3)含量增加,Fe_(3)O_(4 )含量减少;预测模型表明,总铁浓度与pH值和Alk呈负相关关系,与SO_(4)^(2-)和v呈正相关关系,四种因素的影响程度排序为v>pH>Alk>SO_(4)^(2-).

关键词：给水管网管垢铁释放黄水

Numerical simulation of climate response to ultraviolet irradiation forcing

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Advances in Climate Change Research 2019年第3期10卷 133-142页

作者： XIAO zi-Niu DONG Shi zhong Qi State Key Laboratory o f Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute o f Atmospheric PhysicsChinese Academy of SciencesBeijing100029China China Meteorological Administration Training Centre China Meteorological AdministrationBeijing100081China

Using the Whole Atmosphere Community Climate Model, sensitivity experiments are performed to identify the climate response to ultra violet (UV) irradiation forcing. In the experiment, total solar irradiance (TSI) and solar spectral irradiation (SSI) are adopted as solar input from the dataset (1610 2009) reconstructed by Lean. Results show that UV variability has a strong impact on the middle atmosphere. Ozone (0 3) distribution in the atmosphere is sensitive to UV irradiation variability. When UV irradiation is enhanced, the 0 3 content increases at altitudes from 30 km to 60 km and decreases at altitudes from 15 km to 30 km. The atmospheric temperature appears positive anomaly below the mesosphere. Anomalous warmth develops above 35 km with maximum warming anomaly apparent at the stratopause, consistent with the at mospheric distribution of 0 3, which indicates that the ozone heating mechanism plays an important role in wanning. The 0 3 and temperature respond in an opposite manner when the UV irradiation is reduced. Furthermore, the stronger UV forcing leads to a change in the temperature distribution because of the 0 3 heating mechanism. This condition then modulates the zonal wind in the stratosphere and upper troposphere. Although the tropospheric response is weak on a global scale, a notable local response occurs over mid high latitudes in the Northern Hemisphere (NH) during winter. Along with the enhanced zonal wind in the lower stratosphere near the North Pole, the positive phase of the Arctic Oscillation pattern appears over the NH, which causes a temperature increase over mid-latitude Asia. Finally, the behavior evident in the reanalysis data is compared with the results of the numerical experiments. The similar structure of the response fields means the results of simulation experiment is credible to some extent.

关键词： Ultraviolet Ozone Climate variability Numerical simulation

A low-melting-point metal doping strategy for the synthesis of small-sized intermetallic Pt_(5)Ce fuel cell catalysts

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Nano Research 2024年第9期17卷 8112-8118页

作者： zi-Jun Zou Shi-yi yin Yao Tang Sheng-Liang zhong Lei Wang Shi-Long Xu Hai-Wei Liang College of Chemistry and Chemical Engineering Jiangxi Normal UniversityNanchang 330022China Department of Chemistry University of Science and Technology of ChinaHefei 230026China School of Materials and Chemical Engineering Anhui Jianzhu UniversityHefei 230601China

Carbon-supported platinum-lanthanum(Pt-Ln)intermetallic compound(IMC)nanoparticles with high activity and robust stability have been demonstrated as promising cathode catalysts for proton-exchange membrane fuel ***,the preparation of Pt-Ln IMC catalysts needs high-temperature annealing treatment that inevitably causes nanoparticle sintering,resulting in significant reduction of the electrochemical surface area and mass-based ***,we prepare small-sized M-doped Pt_(5)Ce(M=Ga,Cd,and Sb)IMCs catalysts via a low-melting-point metal doping *** speculate that the doping of low-melting-point metals can facilitate the generation of vacancies in the crystal lattice through thermal activation and thus reduce the kinetic barriers for the formation of intermetallic Pt_(5)Ce *** prepared Ga-doped Pt_(5)Ce catalyst exhibits a higher electrochemical active surface area(81 m^(2)·gPt^(-1))and a larger mass activity(0.45 A·mgPt^(-1)at 0.9 V)over the undoped Pt_(5)Ce and commercial Pt/C *** the membrane electrode assembly test,the Ga-doped Pt_(5)Ce cathode delivers a power density of 0.98 W·cm^(-2)at 0.67 V,along with a voltage loss of only 27 mV at 0.8 A·cm^(-2)at the end of accelerated stability test.

关键词： P5Ce low-melting-point metal small-sized intermetallic compound catalysis fuel cells

Quantitative analysis on the phase margin of ADRC

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Control Theory and Technology 2023年第1期21卷 4-15页

作者： Sheng zhong yi Huang Beijing Aerospace Automatic Control Institute Beijing100854China Key Laboratory of Systems and Control Academy of Mathematics and Systems ScienceChinese Academy of SciencesBeijing100190China School of Mathematical Sciences University of Chinese Academy of SciencesBeijing100049China

The paper analyzes and compares the phase margins of four active disturbance rejection control(ADRC)designs,which are based on different common-used extended state observers(ESOs)of various orders,for second-order *** quantitative results indicate that,besides good dynamic response,ADRC can guarantee enough phase *** is also proved that by decreasing the order of ESO,the phase margin can be ***,it is demonstrated that the phase margins of the ADRC-based systems can be almost uninfluenced by the uncertainties of the system ***,the theoretical results are verified by both simulations and experiments on a motion control platform.

关键词： Uncertain system Active disturbance rejection control(ADRC) Extended state observer(ESO) Phase margin Crossover frequency