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Journal of wuhan University of Technology(Materials Science) 2025年第1期40卷 164-170页

作者： wu Min CAO Kailei XIAO Weirong YU Zetai CAO Jierong DING Qingjun LI Jinhui China Railway Construction Corporation Harbour and Channel Engineering Bureau Group Co. LTDZhuhai 519000China Con-struction Headquarters of Zhoushan Liuheng Bridge Phase II Project Zhoushan 316000China China Railway Construction Bridge En-gineering Bureau Group Co. LTDTianjin 300000China State Key Laboratory of Silicate Material for Architecture(wuhan University of Technology) Wuhan 430070China College of Materials Science and Engineering Wuhan Textile UniversityWuhan 430200China

The paper presents experimental investigation results of crack pattern change in cement pastes caused by external sulfate attack(ESA).To visualize the formation and development of cracks in cement pastes under ESA,an X-ray computed tomography(X-ray CT)was used,i e,the tomography system of Zeiss Xradia 510 *** results indicate that X-CT can monitor the development process and distribution characteristics of the internal cracks of cement pastes under ESA with attack *** addition,the C3A content in the cement significantly affects the damage mode of cement paste specimens during sulfate *** damage of ordinary Portland cement(OPC)pastes subjected to sulfate attack with high C3A content are severe,while the damage of sulfate resistant Portland cement(SRPC)pastes is much smaller than that of OPC ***,a quadratic function describes the correlation between the crack volume fraction and development depth for two cement pastes immermed in sulfate solution.

关键词： concrete external sulfate attack damage evolution situ X-ray computed tomography

Liver as a new target organ in Alzheimer's disease:insight from cholesterol metabolism and its role in amyloid-beta clearance

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Neural Regeneration Research 2025年第3期20卷 695-714页

作者： Beibei wu Yuqing Liu Hongli Li Lemei Zhu Lingfeng Zeng Zhen Zhang Weijun Peng Department of Integrated Traditional Chinese&Western Medicine The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Academician Workstation Changsha Medical UniversityChangshaHunan ProvinceChina Yangsheng College of Traditional Chinese Medicine Guizhou University of Traditional Chinese MedicineGuiyangGuizhou ProvinceChina Qinhuangdao Shanhaiguan Pharmaceutical Co. LtdQinhuangdaoHebei ProvinceChina National Clinical Research Center for Mental Disorder The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

Alzheimer's disease,the primary cause of dementia,is characterized by neuropathologies,such as amyloid plaques,synaptic and neuronal degeneration,and neurofibrillary *** amyloid plaques are the primary characteristic of Alzheimer's disease in the central nervous system and peripheral organs,targeting amyloid-beta clearance in the central nervous system has shown limited clinical efficacy in Alzheimer's disease *** abnormalities are commonly observed in patients with Alzheimer's *** liver is the primary peripheral organ involved in amyloid-beta metabolism,playing a crucial role in the pathophysiology of Alzheimer's ***,impaired cholesterol metabolism in the liver may exacerbate the development of Alzheimer's *** this review,we explore the underlying causes of Alzheimer's disease and elucidate the role of the liver in amyloid-beta clearance and cholesterol ***,we propose that restoring normal cholesterol metabolism in the liver could represent a promising therapeutic strategy for addressing Alzheimer's disease.

关键词： ABCA1 Alzheimer's disease amyloid-beta apolipoprotein E cholesterol metabolism liver liver X receptor low-density lipoprotein receptor-related protein 1 peripheral clearance tauroursodeoxycholic acid

基于地基激光雷达人工蒙古栎削度-二元材积方程的构建

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森林工程 2025年第1期41卷 162-173页

作者：李苑鑫吴楚航邢艳秋东北林业大学机电工程学院哈尔滨150040 青岛市即墨区退役军人事务局山东青岛266200

为提高干形复杂树种材积无损估算的精度,利用地基激光雷达点云数据,构建基于人工蒙古栎最优削度模型的二元材积方程。以哈尔滨市城市林业示范基地的蒙古栎人工林为研究对象,使用地基激光雷达扫描获得完整点云数据,经过裁剪、高程归一化... 详细信息

为提高干形复杂树种材积无损估算的精度,利用地基激光雷达点云数据,构建基于人工蒙古栎最优削度模型的二元材积方程。以哈尔滨市城市林业示范基地的蒙古栎人工林为研究对象,使用地基激光雷达扫描获得完整点云数据,经过裁剪、高程归一化、滤波、单木分割和枝叶分离等处理提取树干结构参数。根据蒙古栎干形特征,选用6种削度方程模型(Biging(1984)、Amidon(1984)、孟宪宇(1982)、Kozak(2004)-Ⅱ、曾伟生等(1997)、Max and Burkhart(1976)),通过非线性回归拟合,筛选最优模型并构建削度-二元材积方程。研究结果表明,单木定位识别精度为95.22%,树高和胸径的提取值与实测值决定系数(R2)分别为0.97和0.98;最优削度模型拟合结果的决定系数(R^(2))和均方根误差(RMSE)分别为0.99和0.38 cm。所构建的蒙古栎削度-二元材积方程与现有材积计算方法进行残差分析表明,其估算结果具备可靠性,可为利用地基激光雷达点云数据估算干形复杂的树种材积提供重要技术支持。

关键词：蒙古栎地基激光雷达林木参数削度方程材积方程

Gentiana manshurica Kitagawa prevents acetaminophen-induced acute hepatic injury in mice via inhibiting JNK/ERK MAPK pathway

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World Journal of Gastroenterology 2010年第3期16卷 384-391页

作者： Wang, Ai-Yan Lian, Li-Hua Jiang, Ying-zi wu, Yan-Ling Nan, Ji-xing Yanbian Univ Key Lab Nat Resource Changbai Mt & Funct Mol Minist Educ Coll Pharm Yanji Jilin Peoples R China

AIM:To investigate the in vivo hepatoprotective effects and mechanisms of Gentiana manshurica Kitagawa (GM) in acetaminophen (APAP)-induced liver injury in ***: GM (200, 150 or 50 mg/kg body weight) or N-acetyl-L-cysteine (NAC; 300 mg/kg body weight) was administrated orally with a single dose 2 h prior to APAP (300 mg/kg body weight) injection in ***: APAP treatment significantly depleted hepatic glutathione (GSH), increased serum aspartate aminot ransferase (AST), alanine aminotransferase (ALT) and malonyldialdehyde (MDA) and 4-hydroxynonenal levels, and decreased hepatic activity of glutathione peroxidase (GSH-px) and superoxide dismutase (SOD). However, the pretreatment of GM signif icantly alleviated APAP-induced oxidative stress by increasing GSH content, decreasing serum ALT, AST and MDA, and retaining the activity of GSH-px and SOD in the liver. Furthermore, GM pretreatment can inhibit caspase-3 activation and phosphorylation of c-Jun-NH2-terminal protein kinase 2 (JNK1/2) and extracellular signalregulated kinase (ERK). GM also remarkably attenuated hepatocyte apoptosis confirmed by the terminal deoxynucleotidyl transferase mediated dUTP nick end-labeling ***: Hepatoprotective effects of GM against APAP-induced acute toxicity are mediated either by preventing the decline of hepatic antioxidant status or its direct anti-apoptosis capacity. These results support that GM is a potent hepatoprotective agent.

关键词： Gentiana manshurica Kitagawa Aceta-minophen Oxidative stress Caspase-3 JNK/ERK MAPK

SOLUTION OF THE ENSO DELAYED OSCILLATOR WITH HOMOTOPY ANALYSIS METHOD

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Journal of Hydrodynamics 2009年第1期21卷 131-135页

作者： wu zi-ku School of Science Qingdao Agriculture University Qingdao 266109 China

An ENSO delayed oscillator is considered. The E1 Nino atmospheric physics oscillation is an abnormal phenomenon involved in the tropical Pacific ocean-atmosphere interactions. The conceptual oscillator model should consider the variations of both the eastern and western Pacific anomaly patterns. Using the homotopy analysis method, the approximate expansions of the solution of corresponding problem are constructed. The method is based on a continuous variation from an initial trial to the exact solution. A Maclaurin series expansion provides a successive approximation of the solution through repeated application of a differential operator with the initial trial as the first term. This approach does not require the use of perturbation parameters and the solution series converges rapidly with the number of terms. Comparing the approximate analytical solution by homotopy analysis method with the exact solution, we can find that the homotopy analysis method is valid for solving the strong nonlinear ENSO delayed oscillator model.

关键词： ENSO delayed oscillator homotopy analysis method strong nonlinear

A mild, configurable, flexible CoNi-LDH（v）/Zn battery based on H-vacancy-induced reversible Zn2+ intercalation

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Journal of Energy Chemistry 2025年第1期100卷 498-508页

作者： Xinyue Cheng Dingsheng wu Hao Gao Qingqing Wang Pengfei Lv Sam S.Yoon Qufu Wei Key Laboratory of Eco-textiles Ministry of Education Jiangnan University School of Mechanical Engineering Korea University

Flexible Zn-based batteries have attracted increasing research interest as essential components of wearable energy storage ***,the advancement of flexible aqueous Zn-based batteries based on Co-Ni layered double hydroxide （CoNi-LDH） as the cathode material is hampered by their poor cycling stability and the corrosiveness of alkaline ***,CoNi-LDH nanosheets enriched with H vacancies (CoNi-LDH（v）) were constructed on a flexible carbon cloth （CC） substrate via electrochemical deposition and *** Zn-based battery comprising CoNi-LDH（v）@CC as the cathode exhibited highly reversible conversion reactions and stable operation in 3 M ZnSO4electrolyte （pH=4）.The battery delivered an excellent specific capacity (225 mA h g-1,0.26 mA h cm-2),acceptable cycling stability（53.9%,900 cycles）,and high discharging *** abundant H vacancies served as active sites for the reversible intercalation of Zn2+and the extravasation of NO3-generated channels and space for Zn2+transport and storage,together enabling an excellent Zn2+storage ***,a sandwich-structured solid-state CoNi-LDH（v）@CC//Zn@CC battery was fabricated and was found to exhibit a noteworthy electrochemical performance and mechanical *** a proof of concept,the unencapsulated battery powered a digital watch under various deformation conditions and operated stably for 80 ***,the flexible battery displayed outstanding customizability,maintaining an open-circuit voltage of 1.42 V even after being cut *** proposed engineering strategy contributes to the realization of textiles with truly wearable energy-storage devices.

关键词： CoNi/Zn battery H vacancies Mild aqueous electrolyte Tailorable battery Wearable energy storage device

Syntheses, Crystal Structures and in vitro Anticancer Activities of Dibenzyltin Compounds Based on the N-(2-Phenylacetic acid)-aroyl Hydrazone

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Chinese Journal of Structural Chemistry 2020年第4期39卷 673-681页

作者： JIANG wu-Jiu MO Tian-zi ZHANG Fu-xing KUANG Dai-Zhi TAN Yu-xing Key Laboratory of Functional Metal-organic Compounds of Hunan Province Key Laboratory of Functional Organometallic MaterialsUniversity of Hunan ProvinceCollege of Chemistry and Materials ScienceHengyang Normal UniversityHengyangHunan 421008China

Two dibenzyltin compounds,{[C6H5O(O)C=N-N=C(Ph)COO](m-Cl-C6H4CH2)2-Sn(CH3OH)}2(1)and{[p-Me-C6H4O(O)C=N-N=C(Ph)COO](m-Cl-C6H4CH2)2Sn(CH3OH)}2(2),have been synthesized by microwave“one pot”reaction with benzoylhydrazine(or p-methyl benzhydrazine),phenylglyoxylic acid and di-m-chlorobenzyltin *** 2 contains two crystals 2a and *** compounds have been characterized with IR,elemental analysis,1H,13C and 119Sn NMR spectra,H *** crystals are all binuclear molecules with a Sn2O2 four-membered ring plane,and each Sn atom center is seven-coordinated with[SnO4C2N]to form a distorted pentagonal bipyramidal *** vitro antitumor activities of all compounds and carboplatin were evaluated by MTT against three human cancer cells such as NCI-H460(lung cancer cells),HepG2(liver cancer cells)and MCF7(breast cancer cells),and compound 2 exhibited better antitumor activity.

关键词： organotin complex hydrazine synthesis crystal structure biological activity

Bayesian sequential testing for exponential life system with reliability growth

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Journal of Systems Engineering and Electronics 2011年第6期22卷 1023-1029页

作者： Yunyan xing Xiaoyue wu College of Information Systems and Management National University of Defense Technology Changsha 410073 P. R. China

A Bayesian sequential testing method is proposed to evaluate system reliability index with reliability growth during *** method develops a reliability growth model of repairable systems for failure censored test,and figures out the approach to determine the prior distribution of the system failure rate by applying the reliability growth model to incorporate the multistage test data collected from system ***,the procedure for the Bayesian sequential testing is derived for the failure rate of the exponential life system,which enables the decision to terminate or continue development ***,a numerical example is given to illustrate the efficiency of the proposed model and procedure.

关键词： reliability growth Bayesian method prior distribution sequential testing exponential life system.

Controlling the probability density of quantum systems

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Journal of Systems Engineering and Electronics 2011年第6期22卷 975-981页

作者： Yifan xing Jun wu Institute of Cyber-Systems and Control Zhejiang University Hangzhou 310027 P. R. China

A new method to design a quantum controller which directly controls the probability density function（PDF） of quantum systems is *** on the quantum model from the PDF perspective,two specific control algorithms are proposed with uniform and non-uniform fields,*** a detailed control algorithm with convergence analysis is given for the small error *** appropriately estimating the selected Lyapunov function,more accurate control effect is *** proposed scheme provides a constructive method to find appropriate parameters for controller design.

关键词： quantum control probability density control stochastic distribution control.

Enteromorpha prolifera polysaccharide-Fe(Ⅲ) complex promotes intestinal development as a new iron supplement

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Science China Life Sciences 2025年第1期 219-231页

作者： Yingying Feng Yuying wu Jialu Wang Zhenglin Dong Qian Yu Shuangshuang Xia Chunxue Liu Haihua Wang Xin wu Tianjin Institute of Industrial Biotechnology Chinese Academy of Sciences CAS Key Laboratory of Agro-ecological Processes in Subtropical Region Institute of Subtropical AgricultureChinese Academy of Sciences ANYOU Biotechnology Group Co.Ltd Qingdao Seawin Biotech Group Co. LTD

Iron is a crucial micronutrient, and its deficiency can have detrimental effects on the health of infants. Dietary polysaccharide-iron(Ⅲ) complexes(PICs) are promising for addressing iron deficiency due to their minimal adverse reactions and high iron absorption rate. This study aimed to investigate the effects of dietary Enteromorpha prolifera polysaccharide-Fe(Ⅲ) complex(EP-Fe) on newborns, using 3-day weaned piglets as the iron-deficiency model. Results showed that EP-Fe improved iron levels and promoted intestinal development in piglets. Transcriptome sequencing revealed that EP-Fe increased the survival of intestinal epithelial cells under hypoxia by upregulating the expression of genes that promote the development of the vascular system. Additionally, EP-Fe enhanced the mucosal barrier functions by inhibiting myosin light chain kinase(MLCK)/phosphorylated myosin light chain(p-MLC) signaling pathway to increase the expression of intestinal tight junction proteins. Furthermore, the 16S r RNA gene sequencing of gut microbiota showed that EP-Fe promoted the enrichment of Bacteroides＿fragilis and other gut microbes that can metabolize carbohydrates. In conclusion, EP-Fe is an effective iron supplement for newborns, and it can be developed as a comprehensive nutritional supplement.

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