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Cavitation research with computational fluid dynamics:From Euler-Euler to Euler-Lagrange approach

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Journal of Hydrodynamics 2024年第1期36卷 1-23页

作者： Bin Ji zi-yang wang Huai-yu Cheng Rickard E.Bensow State Key Laboratory of Water Resources Engineering and Management Wuhan UniversityWuhan430072China Department of Mechanics and Maritime Sciences Chalmers University of TechnologyGothenburgSweden

Unsteady cavitating flow often contains vapor structures with a wide range of different length scales,from micro-bubbles to large cavities,which issues a big challenge to precisely investigate its evolution mechanism by computational fluid dynamics(CFD)*** present work reviews the development of simulation methods for cavitation,especially the emerging Euler-Lagrange ***,the progress of the numerical investigation of hot and vital issues is discussed,including cavitation inception,cloud cavitation inner structure and its formation mechanism,cavitation erosion,and cavitation *** is indicated that the Euler-Lagrange method can determine cavitation inception point *** cloud cavitation,the Euler-Lagrange method can reveal the source of microbubbles and their distribution law inside the shedding *** method also has advantages and great potential in assessing cloud cavitation-induced erosion and *** the ever-growing demands of cavitation simulation accuracy in basic research and engineering applications,how to improve the Euler-Lagrange method’s stability and applicability is still an open *** further promote the application of this advanced CFD simulation technology in cavitation research,some key issues are to be solved and feasible suggestions are put forward for further work.

关键词： numerical simulation Euler-Euler method Euler-Lagrange method bubble dynamicsgy,Gothenburg,Sweden

Disturbances rejection optimization based on improved two-degree-of-freedom LADRC for permanent magnet synchronous motor systems

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Defence Technology（防务技术） 2024年第3期33卷 518-531页

作者： Chenggang wang Jianhu Yan Wenlong Li Liang shan Le Sun School of Automation Nanjing University of Science and TechnologyNanjing 210094China

Permanent magnet synchronous motor(PMSM)speed control systems with conventional linear active disturbance rejection control(CLADRC)strategy encounter issues regarding the coupling between dynamic response and disturbance suppression and have poor performance in suppressing complex nonlinear *** order to address these issues,this paper proposes an improved two-degree-of-freedom LADRC(TDOF-LADRC)strategy,which can enhance the disturbance rejection performance of the system while decoupling entirely the system's dynamic and anti-disturbance performance to boost the system robustness and simplify controller parameter *** models that consider total disturbances are developed to design the TDOF-LADRC speed controller ***,to evaluate the control performance of the TDOF-LADRC strategy,its stability is proven,and the influence of each controller parameter on the system control performance is *** on it,a comparison is made between the disturbance observation ability and anti-disturbance performance of TDOF-LADRC and CLADRC to prove the superiority of TDOF-LADRC in rejecting ***,experiments are performed on a 750 W PMSM experimental platform,and the results demonstrate that the proposed TDOF-LADRC exhibits the properties of two degrees of freedom and improves the disturbance rejection performance of the PMSM system.

关键词： Permanent magnet synchronous motor(PMSM) Active disturbance rejection control(ADRC) Disturbance observer Two-degree-of-freedom control Anti-disturbance

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Identification of Important FPGA Modules Based on Complex Network

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Computers, Materials & Continua 2024年第1期78卷 1027-1047页

作者： Senjie Zhang Jinbo wang shan Zhou Jingpei wang Zhenyong Zhang Ruixue wang School of Aeronautics and Astronautics University of Chinese Academy of SciencesBeijing101408China Technology and Engineering Center for Space Utilization Chinese Academy of SciencesBeijing100094China College of Control Science and Engineering Zhejiang UniversityHangzhou310063China College of Computer Science and Technology Guizhou UniversityGuiyang550025China

The globalization of hardware designs and supply chains,as well as the integration of third-party intellectual property(IP)cores,has led to an increased focus from malicious attackers on computing ***,existing defense or detection approaches often require additional circuitry to perform security verification,and are thus constrained by time and resource *** the scale of actual engineering tasks and tight project schedules,it is usually difficult to implement designs for all modules in field programmable gate array(FPGA)*** studies have pointed out that the failure of key modules tends to cause greater damage to the ***,under limited conditions,priority protection designs need to be made on key modules to improve protection *** have conducted research on FPGA designs including single FPGA systems and multi-FPGA systems,to identify key modules in FPGA *** the single FPGA designs,considering the topological structure,network characteristics,and directionality of FPGA designs,we propose a node importance evaluationmethod based on the technique for order preference by similarity to an ideal solution(TOPSIS)***,for the multi-FPGA designs,considering the influence of nodes in intra-layer and inter-layers,they are constructed into the interdependent network,and we propose a method based on connection strength to identify the important ***,we conduct empirical research using actual FPGA designs as *** results indicate that compared to other traditional indexes,node importance indexes proposed for different designs can better characterize the importance of nodes.

关键词： Hardware security FPGA circuits node importance interdependent network

Fake News Detection Based on Cross-Modal Message Aggregation and Gated Fusion Network

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Computers, Materials & Continua 2024年第7期80卷 1521-1542页

作者： Fangfang shan Mengyao Liu Menghan Zhang Zhenyu wang College of Computer Zhongyuan University of TechnologyZhengzhou450007China Henan Key Laboratory of Cyberspace Situation Awareness Zhengzhou450001China

Social media has become increasingly significant in modern society,but it has also turned into a breeding ground for the propagation of misleading information,potentially causing a detrimental impact on public opinion and daily *** to pure text content,multmodal content significantly increases the visibility and share ability of *** has made the search for efficient modality representations and cross-modal information interaction methods a key focus in the field of multimodal fake news *** effectively address the critical challenge of accurately detecting fake news on social media,this paper proposes a fake news detection model based on crossmodal message aggregation and a gated fusion network(MAGF).MAGF first uses BERT to extract cumulative textual feature representations and word-level features,applies Faster Region-based ConvolutionalNeuralNetwork(Faster R-CNN)to obtain image objects,and leverages ResNet-50 and Visual Geometry Group-19(VGG-19)to obtain image region features and global *** image region features and word-level text features are then projected into a low-dimensional space to calculate a text-image affinity matrix for cross-modal message *** gated fusion network combines text and image region features to obtain adaptively aggregated *** interaction matrix is derived through an attention mechanism and further integrated with global image features using a co-attention mechanism to producemultimodal ***,these fused features are fed into a classifier for news *** were conducted on two public datasets,Twitter and *** show that the proposed model achieves accuracy rates of 91.8%and 88.7%on the two datasets,respectively,significantly outperforming traditional unimodal and existing multimodal models.

关键词： Fake news detection cross-modalmessage aggregation gate fusion network co-attention mechanism multi-modal representation

Enantioselective Alkylation of Aldehydes with Organoborons Enabled by Nickel/N-Heterocyclic Carbene Catalysis

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Chinese Journal of Chemistry 2024年第18期42卷 2161-2165页

作者： Song-Yang Liu zi-Chao wang Shi-Liang Shi College of Chemistry and Material Science Shanghai Normal University100 Guilin RoadShanghai 200234China State Key Laboratory of Organometallic Chemistry Shanghai Institute of rganic ChemitryUniversity of Chinee Academy of Scienc Chinese Academy of Sciences345 Lingling RoadShanghai 200032China

Transition-metal-catalyzed asymmetric alkylation of aldehydes represents a straightforward strategy for the synthesis of chiral secondary ***,efficient methods using organoborons as coupling reagents are ***,we report a highly enantioselective nickel-catalyzed alkylation reaction of aldehydes,using readily available alkylborons as nucleophiles.A wide variety of chiral secondary alcohols were prepared from commercially available aldehydes with high *** key to the excellent enantioselectivity and chemoselectivity was the employment of a bulky C2-symmetric chiral NHC *** protocol features excellent enantiocontrol,mild conditions,and good functional group compatibility.

关键词： Enantioselective alkylation Nickel catalysis N-Heterocyclic carbene Organoborons Chiral alcohols Asymmetric catalysis C-C coupling Synthetic methods

Multi-scale Modeling and Finite Element Analyses of Thermal Conductivity of 3D C/SiC Composites Fabricating by Flexible-Oriented Woven Process

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Chinese Journal of Mechanical Engineering 2024年第3期37卷 275-288页

作者： Zheng Sun Zhongde shan Hao Huang Dong wang wang wang Jiale Liu Chenchen Tan Chaozhong Chen Nanjing University of Aeronautics and Astronautics Nanjing 210016China School of Mechanical Engineering Beijing Institute of TechnologyBeijing 100081China CRRC Institute Corporation Limited Beijing 100070China

Thermal conductivity is one of the most significant criterion of three-dimensional carbon fiber-reinforced SiC matrix composites(3D C/SiC).Represent volume element(RVE)models of microscale,void/matrix and mesoscale proposed in this work are used to simulate the thermal conductivity behaviors of the 3D C/SiC *** entirely new process is introduced to weave the preform with three-dimensional orthogonal *** 3D steady-state analysis step is created for assessing the thermal conductivity behaviors of the composites by applying periodic temperature boundary *** RVE models of cuboid,hexagonal and fiber random distribution are respectively developed to comparatively study the influence of fiber package pattern on the thermal conductivities at the ***,the effect of void morphology on the thermal conductivity of the matrix is analyzed by the void/matrix *** prediction results at the mesoscale correspond closely to the experimental *** effect of the porosities and fiber volume fractions on the thermal conductivities is also taken into *** multi-scale models mentioned in this paper can be used to predict the thermal conductivity behaviors of other composites with complex structures.

关键词： 3D C/SiC composites Finite element analyses Multi-scale modeling Thermal conductivity

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The gut microbiome modulate response to immunotherapy in cancer

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Science China Life Sciences 2024年

作者： shan-shan Jiang zi-Ran Kang Ying-Xuan Chen Jing-Yuan Fang Division of Gastroenterology and Hepatology Shanghai Institute of Digestive Disease NHC Key Laboratory of Digestive Diseases State Key Laboratory for Oncogenes and Related Genes Renji Hospital School of Medicine Shanghai Jiao Tong University

Gut microbiota have been reported to play an important role in the occurrence and development of malignant tumors. Currently, clinical studies have identified specific gut microbiota and its metabolites associated with efficacy of immunotherapy in multiple types of *** investigations have elucidated that gut microbiota modulate the antitumor immunity and affect the efficacy of cancer immunotherapy. Certain microbiota and its metabolites may favorably remodel the tumor microenvironment by engaging innate and/or adaptive immune cells. Understanding how the gut microbiome interacts with cancer immunotherapy opens new avenues for improving treatment strategies. Fecal microbial transplants, probiotics, dietary interventions, and other strategies targeting the microbiota have shown promise in preclinical studies to enhance the immunotherapy. Ongoing clinical trials are evaluating these approaches. This review presents the recent advancements in understanding the dynamic interplay among the host immunity, the microbiome, and cancer immunotherapy, as well as strategies for modulating the microbiome, with a view to translating into clinical applications.

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Knockdown of neuronal DAF-15/Raptor promotes healthy aging in ***

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Journal of Genetics and Genomics 2024年第5期51卷 507-516页

作者： Xiao Zang Qi wang Hanxin Zhang Yiyan Zhang zi wang zixing Wu Di Chen Model Animal Research Center of Medical School Nanjing UniversityNanjingJiangsu 210061China Zhejiang University-University of Edinburgh Institute School of MedicineZhejiang UniversityHainingZhejiang 314400China Department of Colorectal Surgery The Second Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310058China

The highly conserved target of rapamycin(TOR)pathway plays an important role in aging across *** studies have established that inhibition of the TOR complex 1(TORC1)significantly extends lifespan in Caenorhabditis ***,it has not been clear whether TORC1 perturbation affects aging in a spatiotemporal ***,we apply the auxin-inducible degradation tool to knock down endogenous DAF-15,the *** ortholog of regulatory associated protein of TOR(Raptor),to characterize its roles in *** or tissue-specific inhibition of DAF-15 during development results in various growth defects,whereas neuron-specific knockdown of DAF-15 during adulthood significantly extends lifespan and *** neuronal DAF-15 deficiency-induced longevity requires the intestinal activities of DAF-16/FOXO and PHA-4/FOXA transcription factors,as well as the AAK-2/AMP-activated protein kinaseαcatalytic *** profiling reveals that the neuronal DAF-15 knockdown promotes the expression of genes involved in *** findings define the tissue-specific roles of TORC1 in healthy aging and highlight the importance of neuronal modulation of aging.

关键词： Aging targetof rapamycin DAF-15 DAF-16 C.elegans

Insights into sensitizing and eliciting capacity of gastric and gastrointestinal digestion products of shrimp(Penaeus vannamei)proteins in BALB/c mice

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Food Science and Human Wellness 2024年第1期13卷 339-348页

作者： Yao Liu Songyi Lin Kexin Liu shan wang wang Li Na Sun National Engineering Research Center of Seafood School of Food Science and TechnologyDalian Polytechnic UniversityDalian 116034China Collaborative Innovation Center of Seafood Deep Processing Dalian Polytechnic UniversityDalian 116034China

Shrimp(Penaeus vannamei)proteins have been shown an allergenic potential;however,little information is available on the sensitizing and eliciting capacity of shrimp protein digestion *** this study,a BALB/c mice model was used to explore the allergenicity of shrimp protein sample(SPS)and their gastric and gastrointestinal digestion products(GDS/GIDS).As compared with the SPS groups,the GDS/GIDS groups caused lower specific immunoglobulins(Ig E/Ig G1)levels(Pzing and eliciting capacity.

关键词： Penaeus vannamei Allergenicity Digestion BALB/c mice model

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