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Journal of Materials Science & Technology 2022年第33期128卷 107-117页

作者： Yuqiao Dong Guang-Ling Song Jiawei Zhang Yahui Gao zi ming wang Dajiang Zheng Center for Marine Materials Corrosion and Protection College of MaterialsXiamen UniversityXiamen 361005China School of Life Sciences and Key Laboratory of Ministry of Education for Coastal and Wetland Ecosystems Xiamen UniversityXiamen 361102China Department of Ocean Science and Engineering Southern University of Science and TechnologyShenzhen 518055China The University of Queensland School of Mechanical and Mining EngineeringDivision of Materials EngineeringSt LuciaQld 4072Australia

The assemblages of unicellular microalgae and bacteria in phytoplankton communities can generally result in biodeterioration of metals in marine environment.In this study,the self-promoted biofouling mechanism underneath red-tide alga Phaeodactylum tricornutum and its symbiotic bacterium Bacillus altitudinis was systematically revealed.The mutualistic interaction of the bacteria and algae quadrupled the corrosion rate in comparison to the individual effect of the bacterium or algal strain alone.Reversely,the corroded metal appeared to be an accelerator that can stimulate the activity of the P.tricornutum and aggravate the biological pollution based on the result of 62.3%up-regulation of the key photosynthesis genes.The corrosion-biofouling-accelerated corrosion-deteriorated biofouling formed a vicious cycle.

关键词： Algal-bacterial symbiosis Marine biofouling Carbon steel Corrosion products

Photoinduced Floquet higher-order Weyl semimetal in C_(6) symmetric Dirac semimetals

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Chinese Physics B 2024年第6期33卷 109-117页

作者：许欣欣王梓名许东辉陈垂针 Institute for Advanced Study and School of Physical Science and Technology Soochow UniversitySuzhou 215006China Department of Physics and Chongqing Key Laboratory for Strongly Coupled Physics Chongqing UniversityChongqing 400044China Center of Quantum Materials and Devices Chongqing UniversityChongqing 400044China

Topological Dirac semimetals are a parent state from which other exotic topological phases of matter, such as Weyl semimetals and topological insulators, can emerge. In this study, we investigate a Dirac semimetal possessing sixfold rotational symmetry and hosting higher-order topological hinge Fermi arc states, which is irradiated by circularly polarized light. Our findings reveal that circularly polarized light splits each Dirac node into a pair of Weyl nodes due to the breaking of time-reversal symmetry, resulting in the realization of the Weyl semimetal phase. This Weyl semimetal phase exhibits rich boundary states, including two-dimensional surface Fermi arc states and hinge Fermi arc states confined to six hinges.Furthermore, by adjusting the incident direction of the circularly polarized light, we can control the degree of tilt of the resulting Weyl cones, enabling the realization of different types of Weyl semimetals.

关键词： Dirac semimetals Weyl semimetals periodic driving higher-order topology

Flood management of Dongting Lake after operation of Three Gorges Dam

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Water Science and Engineering 2017年第4期10卷 303-310页

作者： Xi-jun Lai zi-ming wang Key Laboratory of Watershed Geographic Sciences Nanjing Institute of Geography&LimnologyChinese Academy of Sciences(CAS)Nanjing 210008China Zhejiang Institute of Hydraulics and Estuary Hangzhou 310020Chin

Full operation of the Three Gorges Dam(TGD) reduces flood risk of the middle and lower parts of the Yangtze River Basin. However,Dongting Lake, which is located in the Yangtze River Basin, is still at high risk for potentially severe flooding in the future. The effects of the TGD on flood processes were investigated using a hydrodynamic model. The 1998 and 2010 flood events before and after the operation of the TGD, respectively, were analyzed. The numerical results show that the operation of the TGD changes flood processes, including the timing and magnitude of flood peaks in Dongting Lake. The TGD can effectively reduce the flood level in Dongting Lake, which is mainly caused by the flood water from the upper reach of the Yangtze River. This is not the case, however, for floods mainly induced by flood water from four main rivers in the catchment. In view of this, a comprehensive strategy for flood management in Dongting Lake is required. Non-engineering measures, such as warning systems and combined operation of the TGD and other reservoirs in the catchment, as well as traditional engineering measures, should be further improved. Meanwhile, a sustainable philosophy for flood control, including natural flood management and lake restoration, is recommended to reduce the flood risk.

关键词： Three Gorges Dam Flood control Water level Hydrodynamic model Dongting Lake

Side population cells from HXO-Rb44 retinoblastoma cell line have cancer-initiating property

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International Journal of Ophthalmology(English edition) 2011年第5期4卷 461-465页

作者： Jun-Jun She, zi-ming wang Department of General Surgery First Affiliated Hospital of Medical College Xi'an Jiaotong University Xi'an 710061 Shaanxi Province China Department of Mathematics Xidian University Xi'an 710071 Shaanxi Province China Department of Urology Second Affiliated Hospital of Medical College Xi'an Jiaotong University Xi'an 710004 Shaanxi Province China

AIM: To ascertain whether side population (SP) cells in HXO-Rb44 retinoblastoma cell line have cancer stem cell-like property in vitro and in vivo. METHODS: We analyzed and sorted SP from HXO-Rb44 retinoblastoma cell line by Hoechst 33342 staining on flow cytometry. SP and NSP cells were determined their ability of proliferation and self-renewal by SP reanalysis, soft agar assay and tumor sphere assay in vitro. Clone formation was detected by seeding HXO-Rb44 and HXO-Rb44 -RFP cells into soft agar. The expression of ABCGZ MDRI Bmi-1 and Oct-4 was determined by RT-PCR between SP and non-SP (NSP) cells. Moreover, they were injected into nude mice to determine their tumorigency in vivo. RESULTS: SP from HXO-Rb44 retinoblastoma cell line could grow clonally in soft agar assays and form tumor spheres from single cells in conditioned media. The expressions of ABCG2, MDRI Bmi-1 and Oct-4 were significantly higher in SP than NSP cells. As few as SP cells resulted in tumor formation in 6 of 12 injected sites, however, the injection of NSP cells failed to form new tumor. CONCLUSION: SP cells isolated by Hoechst 33342 from the HXO-Rb44 retinoblastoma cell line had property of high tumorigency in vivo and in vitro Therefore, SP might be a target while developing retinoblastoma therapies.

关键词： side population self-renewal retinoblastoma HXO-Rb44

Isoflavones and Prostate Cancer： A Review of Some Critical Issues

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Chinese Medical Journal 2016年第3期129卷 341-347页

作者： Hong-Yi Zhang Jie Cui Ye Zhang Zhen-Long wang Tie Chong zi-ming wang Department of Urology Second Affiliated Hospital of Xi'an Jiaotong University Xi'an Shaanxi 710004 China Department of Urology Yan'an University Affiliated Hospital Yan'an Shaanxi 716000 China Department of Oncology Yan'an University Affiliated Hospital Yan'an Shaanxi 716000 China

Objective： The purpose of this review is to discuss some critical issues of isoflavones protective against the development of prostate cancer （PCa）.Data Sources： Data cited in this review were obtained primarily from PubMed and Embase from 1975 to 2015.Study Selection： Articles were selected with the search terms ＆quot;isoflavone＆quot;, ＆quot;Phytoestrogen＆quot;, ＆quot;soy＆quot;, ＆quot;genistin＆quot;, and ＆quot;PCa＆quot;.Results： Isoflavones do not play an important role on prostate-specific antigen levels reduction in PCa patients or healthy men.The effect ofisoflavones on sex hormone levels and PCa risk may be determined by equol converting bacteria in the intestine, specific polymorphic variation and concentrations of isoflavones.The intake of various types of phytoestrogens with lower concentrations in the daily diet may produce synergistic effects against PCa.Moreover, prostate tissue may concentrate isoflavones to potentially anti-carcinogenic levels.In addition, it is noteworthy that isoflavones may act as an agonist in PCa.Conclusions： Isoflavones play a protective role against the development of PCa.However, careful consideration should be given when isoflavones are used in the prevention and treatment of PCa.

关键词： Isoflavone Phytoestrogen Prostate Cancer

To explore the mechanism of anticancer prescription in treatment of gastric cancer based on network pharmacology and molecular docking

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Cancer Advances 2022年第5期5卷 1-12页

作者： zi-Hong Wu zi-ming wang En-Feng Song Bei Yin Affiliated Hospital of Chengdu University of Traditional Chinese Medicine Chengdu 610072China Department of Traditional Chinese Medicine Renmin Hospital of Wuhan UniversityWuhan 430060China The Second Clinical Medical College of Guangzhou University of Chinese Medicine Guangzhou 510504China.

Objective:To explore the mechanism of anticancer prescription in treatment of gastric cancer based on network pharmacology and molecular docking.Methods:By searching TCMSP database,the active components and corresponding targets of anticancer prescriptions were screened out.GeneCards,PharmGkb,OMIM,DrugBank and TTD database were used to collect action targets of gastric cancer.And Venny 2.1 software was used to screen drug-disease co-action targets.Then,String and Cytoscape software were used to analyze and construct PPI network,and Cytonca plug-in was used to cany out topology analysis to select the core targets.ClueGO plugin was used for GO function enrichment analysis and KEGG pathway analysis.Finally,the AutoDock software was used to conduct molecular docking between the core target and the main active ingredients of the anticancer prescription.Results:Sixty-four active compounds,159 common targets and 12 core targets of anti-cancer prescriptions were screened out,which involved 2373 GO functions and 172 KEGG pathways.Finally,the core target proteins MAPKI TP53 and JUN were screened and molecularly docked with 8 major active components.Among them,theflavonoid quercetin and luteolin had the best binding activity with MAPK1,Quercetin baicalin also had high binding activity with FOS.Conclusion:The preliminary study showed that flavonoids were an important active ingredient in the anti-cancer prescription,which mainly treated gastric cancer through multiple targets and multiple pathways,such as the effect of MAPK1 on chemical carcinogenesis in reaction with drugs,bacterial and viral infection and cell apoptosis.

关键词： network pharmacology molecular docking,anticancer prescription gastric cance

Gastrointestinal symptoms as the first sign of chronic granulomatous disease in a neonate: A case report

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World Journal of Clinical Cases 2021年第32期9卷 9997-10005页

作者： Er-Yan Meng zi-ming wang Bing Lei Li-Hong Shang Division of Neonatology The Third Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052Henan ProvinceChina Chongqing Medical College Chongqing 400016China

BACKGROUND Chronic granulomatous disease(CGD)characterized by recurrent and severe bacterial and fungal infections is most common in childhood.CASE SUMMARY We reported a 24-d-old male infant who developed gastrointestinal symptoms as the first sign of CGD.CONCLUSION Gastrointestinal symptoms representing the first sign of CGD are very rare,and prompt diagnosis and treatment with broad-spectrum antibiotics were of crucial importance.

关键词： Chronic granulomatous disease Gastrointestinal symptoms Infant Neonate Fever Diarrhea

The infection of Mycoplasma hominis after total knee replacement： Case report and literature review

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Chinese Journal of Traumatology 2017年第4期20卷 243-245页

作者： Hong-Jiu Qiu Wei-Ping Lu Min Li zi-ming wang Quan-Yin Du Ai-Min wang Yan Xiong Department of Orthopedics. Daping Hospital. Third Military Medical University. Chongqing 400042 China Department of Clinical Laboratory. Daping Hospital. Third Military Medical University. Chongqing 400042. China

霉浆菌 hominis 感染是在联合代替以后的稀罕手术后的复杂并发症。基于我们的知识，仅仅有二个案例，朝鲜当前在整个世界报导。在我们的医院里的全部的膝代替以后的手术后的霉浆菌 hominis 感染的一个案例在这篇文章被报导。它通过集体... 详细信息

霉浆菌 hominis 感染是在联合代替以后的稀罕手术后的复杂并发症。基于我们的知识，仅仅有二个案例，朝鲜当前在整个世界报导。在我们的医院里的全部的膝代替以后的手术后的霉浆菌 hominis 感染的一个案例在这篇文章被报导。它通过集体分光计和霉浆菌耕作被证实并且由第一阶段清创术对待，聚乙烯插入在操作以后与敏感抗菌素相结合的代替，然后排水和灌溉。当红血球沉积率(ESR ) 在高水平留下时，我们观察到 C 反应蛋白质(CRP ) 与疾病的发展铺平相互关联，显示在膝关节代替和 CRP 引起的霉浆菌 hominis 感染之间的关联。这研究试图报导案例并且考察相关文学。

关键词：支原体感染病例报告膝关节置换复习文献合并红细胞沉降率

Gasification kinetics of bulk coke in the CO2/CO/H2/H2O/N2 system simulating the atmosphere in the industrial blast furnace

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International Journal of Minerals,Metallurgy and Materials 2019年第10期26卷 1247-1257页

作者： Min-min Sun Jian-liang Zhang Ke-jiang Li Ke Guo zi-ming wang Chun-he Jiang School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China School of Chemical Engineering The University of QueenslandSt LuciaQLD 4072Australia Sinosplendor Engineering&Technology Co. Ltd.Tianjin 300452China

The gasification characteristics and gasification kinetics of coke in complex CO2/CO/H2/H2O/N2 systems similar to the gas system of industrial blast furnace (BF) were studied by the method of isothermal thermogravimetric analysis. The experimental gas compositions and the corresponding temperature were chosen according to data reported for industrial BFs. The gasification behavior of coke was described by the Random Pore Model (RPM), Volumetric Model (VM), and Grain Model (GM). Results showed that the gas composition of the coke gasification zone in BF changes slightly and that the temperature is the most important factor affecting coke gasification. The lower activation energy of coke samples (Coke Reaction Index (CRI)>50) is due to the high Fe2O3 in the ash, lower degree of graphitization, and larger pore structure. In addition, the choice of kinetic model does not differ substantially in describing the gasification mechanism of coke in a BF.

关键词： blast furnace coke gasification kinetics gas system

Global view on virus infection in non-human primates and implications for public health and wildlife conservation

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Zoological Research 2021年第5期42卷 626-632页

作者： Zhi-Jin Liu Xue-Kun Qian Min-Heng Hong Jia-Li Zhang Da-Yong Li Tian-Han wang Zuo-Min Yang Li-Ye Zhang zi-ming wang Hua-Jian NieKe-Yue Fan Xiong-Fei Zhang Meng-Meng Chen Wei-Lai Sha Christian Roos ming Li College of Life Sciences Capital Normal UniversityBeijing 100048China College of Life Sciences Hebei UniversityBaodingHebei 071002China CAS Key Laboratory of Animal Ecology and Conservation Biology Institute of ZoologyBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China College of Life Sciences China West Normal UniversityNanchongSichuan 637009China College of Life Sciences Qufu Normal UniversityQufuShandong 273100China Primate Genetics Laboratory German Primate CenterLeibniz Institute for Primate ResearchGoettingen 37077Germany State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China Gene Bank of Primates German Primate CenterLeibniz Institute for Primate ResearchGoettingen 37077Germany Center for Excellence in Animal Evolution and Genetics Chinese Academy of SciencesKunmingYunnan 650223China

Viruses can be transmitted from animals to humans(and vice versa)and across animal species.As such,host-virus interactions and transmission have attracted considerable attention.Non-human primates(NHPs),our closest evolutionary relatives,are susceptible to human viruses and certain pathogens are known to circulate between humans and NHPs.Here,we generated global statistics on virus infections in NHPs(VI-NHPs)based on a literature search and public data mining.In total,140 NHP species from 12 families are reported to be infected by 186 DNA and RNA virus species,68.8%of which are also found in humans,indicating high potential for crossing species boundaries.

关键词： species. primates attention