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大熊猫国家公园小相岭片区及周边居民对生态旅游发展的感知及参与意愿

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生态学杂志 2024年第8期43卷 2433-2439页

作者：胡佳媛郑海朋杨兵代勤龙周文嘉四川省大熊猫科学研究院成都610081 四川栗子坪国家级自然保护区管理局四川石棉625400

以社区参与模式发展生态旅游,既能提高当地居民生态旅游的参与和归属感,又利于加强居民对生态旅游的认同和支持度,促进人与自然和谐共生。以大熊猫国家公园小相岭片区为例,采用问卷和访谈结合的方法,调研当地生态旅游发展现状与发展过... 详细信息

以社区参与模式发展生态旅游,既能提高当地居民生态旅游的参与和归属感,又利于加强居民对生态旅游的认同和支持度,促进人与自然和谐共生。以大熊猫国家公园小相岭片区为例,采用问卷和访谈结合的方法,调研当地生态旅游发展现状与发展过程中居民的民族文化感知、经济感知和参与意愿。结果表明:目前研究区域内居民生态旅游参与度较低,获取收益较少;民族文化感知对居民的参与意愿有显著正影响,路径系数为0.30(P<0.01);经济感知对居民的参与意愿具有显著正影响,路径系数为0.65(P<0.001),同时,经济感知在民族文化感知对参与意愿的正影响中起部分中介作用,中介效应为0.43(P<0.01)。为提升居民参与意愿,研究从民族文化融入、产品优化和专业培训3个方面提出建议,为国家公园的可持续发展提供参考。

关键词：生态旅游社区参与经济感知民族文化感知参与意愿

两坝间河道高含沙水流驱动的下游船闸阀门井水位异常特征分析

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长江科学院院报 2024年第9期41卷 79-85,92页

作者：杨忠勇李林孙诗为张勇唐艳平王紫阳刘新健徐杨三峡大学水利与环境学院湖北宜昌443002 长江三峡通航管理局湖北宜昌443000 重庆市建筑科学研究院有限公司重庆400042 中国长江电力股份有限公司智慧长江与水电科学湖北省重点实验室湖北宜昌443000

葛洲坝船闸充水阀门井与输水廊道进水口水体相连,1993年洪季期间曾发生过阀门井水位异常升高,影响船闸设备设施安全等问题。为分析葛洲坝一号船闸充水阀门井水位异常升高的根本原因,基于Mike三维水沙数值模型,模拟分析了不同流量和含沙... 详细信息

葛洲坝船闸充水阀门井与输水廊道进水口水体相连,1993年洪季期间曾发生过阀门井水位异常升高,影响船闸设备设施安全等问题。为分析葛洲坝一号船闸充水阀门井水位异常升高的根本原因,基于Mike三维水沙数值模型,模拟分析了不同流量和含沙量级别下的河道水流和含沙量垂向分布结构特征,进而计算阀门井水位异常升高值与河道水流和含沙量的关系,反演1993年洪季葛洲坝一号船闸两个阀门井出现的水位异常现象。研究结果表明,葛洲坝一号船闸阀门井水位异常超过阈值0.5 m的流量和含沙量条件分别约为(30 000 m^(3)/s, 2.85 kg/m^(3)),(40 000 m^(3)/s, 1.42 kg/m^(3)),(50 000 m^(3)/s, 1.23 kg/m^(3))。受三峡水库及上游梯级水库蓄水拦沙、退耕还林政策等因素的影响,未来葛洲坝船闸出现高含沙水流导致阀门井水位异常升高>0.5 m的可能性极小,但在三峡水库排沙泄洪期间仍应引起重视。研究成果可为葛洲坝一号船闸安全营运和科学管理提供参考依据。

关键词：葛洲坝船闸阀门井水沙数值模拟高含沙水流水位异常

物化提纯法提纯SiC用高纯石墨制品技术研究

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炭素技术 2024年第1期43卷 75-78页

作者：吴忠举白杨丰田冬龙成洋洋李剑张婷山西中电科新能源技术有限公司山西太原030024

通过对现有石墨提纯技术梳理,提出物化提纯法的概念、反应机理及提纯流程,提出物化提纯法的3个重要技术指标,即工艺气体选择、工艺炉压选择和工艺温度选择,根据提纯流程对第3代半导体SiC用高纯石墨制品进行试验,通过试验证明,使用物化... 详细信息

通过对现有石墨提纯技术梳理,提出物化提纯法的概念、反应机理及提纯流程,提出物化提纯法的3个重要技术指标,即工艺气体选择、工艺炉压选择和工艺温度选择,根据提纯流程对第3代半导体SiC用高纯石墨制品进行试验,通过试验证明,使用物化提纯法对第3代半导体碳化硅用石墨制品进行提纯,其纯度可以稳定在99.9995%~99.9999%,并且可以定向去除第3代半导体碳化硅用高纯石墨制品中B和Al元素,完全可以满足第3代半导体碳化硅用高纯石墨制品的纯度要求。

关键词：高纯石墨制品物化提纯法碳化硅定向去除

Changes in physicochemical characteristics of wheat flour and quality of fresh wet noodles induced by microwave treatment

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Grain & Oil Science and Technology 2024年第3期7卷 177-185页

作者： Jian Zhang Xuejie Li Xiujuan Ren Yanxia An Xiaoyan Song yang Zhao Yaqing Wen Weifeng Zhang College of Food Science and Technology Henan Agricultural UniversityZhengzhou 450000Henan ProvinceChina School of Food Science and Engineering Zhengzhou University of Science and TechnologyZhengzhou 450064Henan ProvinceChina

Fresh wet noodles(FWN) are popular staple foods due to its unique chewy texture and favorable taste. However,the development of FWN is limited by its short shelf life and high browning rate. It has been found that the quantity of original microorganisms in wheat flour produced by traditional method is relatively high, which is detrimental to the processing quality and storage stability of FWN. Consequently, it becomes imperative to decrease microorganisms in wheat flour. Microwave treatment has been regarded as a promising method in the food industry due to its potential in inhibiting microbial growth and inactivating enzymes without causing adverse effect on the food quality. This study aims to investigate the effects of microwave treatment of wheat kernels under different powers(1, 2, 3, 4, 5 kW) on the physicochemical properties of wheat flour and the quality of FWN. The results revealed that microwave treatment had a significant effect on microbial inhibition and enzyme inactivation, wherein the total plate count(TPC) and yeast and mold counts(YMC) decreased by 0.87 lg(CFU/g) and 1.13 lg(CFU/g) respectively, and PPO activity decreased from 11.40 U to 6.31 U. The dough quality properties, such as stability, extensibility, and starch viscosity, improved significantly under different microwave conditions. Confocal laser scanning microscopy(CLSM) images indicated that starch and proteins aggregated gradually in treated flour, altering rheological properties of dough. From the results of scanning electron microscopy(SEM), microwave treatment led to the appearance of disrupted structure in the gluten proteins, but the secondary structure of proteins altered slightly. Rheological properties of dough confirmed that the microwave treatment greatly affected processing characteristics of wheat flour products, with significant advantageous consequences on product quality, especially for textural properties of FWN. Furthermore, FWN darkening could be inhibited noticeably aft

关键词： Microwave treatment Sterilization Confocal laser scanning microscopy Rheological properties Protein structures

住院医师为主导联合案例教学法在全科专业住院医师规范化培训中的应用

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中国基层医药 2024年第1期31卷 130-134页

作者：张云红赵艳萍杨渝张碧芳龙珑赵义娟大理白族自治州人民医院全科医学科大理671000

目的探讨住院医师为主导联合案例教学法(case-based learning,CBL)的病例讨论形式在全科专业住院医师规范化培训(简称住培)临床教学活动中的运用价值。方法选择2018年9月至2022年9月在大理州人民医院接受住培的全科专业住院医师共153人... 详细信息

目的探讨住院医师为主导联合案例教学法(case-based learning,CBL)的病例讨论形式在全科专业住院医师规范化培训(简称住培)临床教学活动中的运用价值。方法选择2018年9月至2022年9月在大理州人民医院接受住培的全科专业住院医师共153人,其中参加住院医师主导教学病例讨论的103人为观察组,参加传统病例讨论的50人作为对照组。通过对住院医师及指导老师的问卷调查,了解两组住院医师教学目标达标情况、指导老师的带教体会以及师生的满意程度和支持程度。结果观察组在住院医师教学目标达标和满意程度评分等方面均优于对照组[(3.83±0.82)分比(3.01±0.65)分,t=6.98,P<0.001;(3.61±0.43)分比(3.25±0.83)分,t=3.96,P<0.001];观察组住院医师和指导老师均肯定了住院医师主导的病例讨论在住培教学中的可行性、有效性。结论住院医师为主导联合案例教学法可以更好地激发住院医师的主动学习积极性,培养其岗位胜任力,同时促进教学相长,值得在住培的教学病例讨论中进一步推广。

关键词：教育,医学全科医生在职培训医院,教学住院医师规范化培训住院医师主导

Direct detection of C9orf72 hexanucleotide repeat expansions by nanopore biosensor

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Chinese Chemical Letters 2024年第5期35卷 351-354页

作者： Xinqiong Li Guocheng Rao Xi Peng Chan yang Yanjing Zhang Yan Tian Xianghui Fu Jia Geng State Key Laboratory of Biotherapy and Cancer Center West China HospitalSichuan University and Collaborative Innovation Center of BiotherapyChengdu 610041China Division of Endocrinology and Metabolism West China School of Medicine/West China HospitalSichuan UniversityChengdu 610041China Department of Endocrinology and Metabolism Affiliated Hospital of North Sichuan Medical CollegeNorth Sichuan Medical CollegeNanchong 637000China Division of Endocrinology and Metabolism National Clinical Research Center for GeriatricsState Key Laboratory of Biotherapy and Cancer CenterWest China HospitalSichuan University and Collaborative Innovation Center of BiotherapyChengdu 610041China Department of Laboratory Medicine State Key Laboratory of BiotherapyMed-X Center for ManufacturingWest China HospitalSichuan University and Collaborative Innovation CenterChengdu 610041China Tianfu Jincheng Laboratory City of Future MedicineChengdu 641400China

Diagnostic C9orf72 hexanucleotide repeat expansions(C9-HRE)is essential for the early and accurate diagnosis of amyotrophic lateral sclerosis(ALS)and will provide support for the prognosis and gene therapy of *** the present study,by combining catalytic hairpin assembly(CHA)with Mycobacterium smegmatis porin A(MspA)nanopore,a new nanopore-based strategy for the detection of C9-HRE was *** than 30 repeats of C9-HRE could be detected via this method,and the results have the potential to help distinguish between patients and healthy ***,the method demonstrated its great specificity for C9-HRE by identifying other repeat *** the high selectivity,this approach had been successfully used to detect C9-HRE in cell and blood samples with high *** detection strategy is user-friendly and has a strong anti-interference ability,thus providing a powerful tool for clinical diagnosis.

关键词： MspA nanopore C9orf72 HRE Detection Biosensor Catalytic hairpin assembly

通过主客体能量传递机制的青绿色发光LED的制备及性能

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化工新型材料 2024年第9期52卷 129-135页

作者：龙顺马佳俊杨军校环境友好能源材料国家重点实验室西南科技大学绵阳621010 西南科技大学材料与化学学院绵阳621010

绿光作为三基色之一,具有不可忽视的作用。通过Suzuki偶联反应合成了芘基多孔有机聚合物(Py-POP),采用傅里叶变换红外光谱仪、荧光分光光度计、N 2吸附-脱附实验、X射线衍射仪和扫描电子显微镜对其化学结构、晶体结构和微观形貌进行了... 详细信息

绿光作为三基色之一,具有不可忽视的作用。通过Suzuki偶联反应合成了芘基多孔有机聚合物(Py-POP),采用傅里叶变换红外光谱仪、荧光分光光度计、N 2吸附-脱附实验、X射线衍射仪和扫描电子显微镜对其化学结构、晶体结构和微观形貌进行了表征。通过Hyperchem软件对Py-POP空间结构进行了模拟,模拟结果表明二乙烯基硅氧烷-双苯并环丁烯(DVSBCB)单体能够进入Py-POP孔道,先通过热开环反应得到预聚物Py-POP/pre-p-DVSBCB(pre-p-DVSBCB为二乙烯基硅氧烷-双苯并环丁烯预聚物),再进一步反应得到芘基交联固化物Py-POP/p-DVSBCB(p-DVSBCB为pre-p-DVSBCB的交联固化物),Py-POP/p-DVSBCB能够作为封装层和荧光层。由于pre-p-DVSBCB和p-DVSBCB具有紫外吸收-蓝光发射的特性,因此二者作为主体材料(Host)能够通过能量转移过程将蓝光转移到Py-POP客体材料(Ghost)。发光二极管(LED)光源性能测试结果表明,Host-Ghost能量传递体系能够减少蓝光,同时能够得到具有良好青绿色发光行为的LED光源。

关键词：多孔有机聚合物苯并环丁烯能量传递 LED

Smad8 is involvement in follicular development via the regulation of granulosa cell growth and steroidogenesis in mice

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BIOCELL 2024年第1期48卷 139-147页

作者： DAOLUN YU DEYONG SHE KAI GE LEI yang RUINA ZHAN SHAN LU YAFEI CAI College of Biotechnology and Pharmaceutical Engineering West Anhui UniversityLu’an237012China Lu’an Academy of Agricultural Sciences Lu’an237001China College of Life Sciences Anhui Normal UniversityWuhu241000China College of Animal Science and Technology Nanjing Agricultural UniversityNanjing210095China

Background:SMAD family proteins(SMADs)are crucial transcription factors downstream of transforming growth factor beta(TGF-ß)/SMAD signaling pathways that have been reported to play a pivotal role in mammalian ***,the role of SMAD family member 8(SMAD8,also known as SMAD9),a member of the SMAD family,in mammalian reproduction remains ***:We employed RNA interference techniques to knock down Smad8 expression in mouse granulosa cells(GCs)to investigate the effects of Smad8 on GC growth and ***:Our findings revealed a significant decrease in the proliferative capacity and a substantial increase in the apoptosis rate of GCs after transfection with Smad8-siRNA for 48 *** hormone assays demonstrated a significant decrease in estradiol(E2)levels,whereas progesterone(P4)remained *** mechanistic analysis showed that the mRNA expression of proliferating cell nuclear antigen(Pcna),Cyclin D2,cell cycle-dependent kinase 4(Cdk4),B-cell lymphoma-2(Bcl-2),estrogen receptor(Er),luteinizing hormone receptor(Lhr)and cytochrome P450 family 19 subfamily A member 1(Cyp19a1)significantly ***,the mRNA of cysteine aspartate proteinase 3(Caspase 3)significantly increased,wheras Bcl2-associated X(Bax),folliclestimulating hormone receptor(Fshr)and cytochrome P450 family 11 subfamily A member 1(Cyp11a1)remained unchanged compared to the ***:This study indicates that Smad8 knockdown inhibits cell proliferation,promotes apoptosis,reduces Er and Lhr transcription,and decreases E2 production in mouse *** findings suggest that Smad8 may serve as a novel genetic marker for mammalian reproduction.

关键词： Mouse Smad8 RNA interference Granulosa cells Growth and steroidogenesis

Resilience-Oriented Load Restoration Method and Repair Strategies for Regional Integrated Electricity-Natural Gas System

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Energy Engineering 2024年第4期121卷 1091-1108页

作者： Keqiang Wang Pengyang Zhao Changjian Wang zimeng Zhang Yu Zhang Jia Lu Zedong yang Baicheng Power Supply Company State Grid Jilin Electric Power Co.Ltd.Baicheng137000China School of Electrical Engineering Northeast Electric Power UniversityJilin132012China

The rising frequency of extreme disaster events seriously threatens the safe and secure operation of the regional integrated electricity-natural gas system(RIENGS).With the growing level of coupling between electric and natural gas systems,it is critical to enhance the load restoration capability of both *** paper proposes a coordinated optimization strategy for resilience-enhanced RIENGS load restoration and repair scheduling and transforms it into a mixed integer second-order cone programming(MISOCP)*** proposed model considers the distribution network reconfiguration and the coordinated repair strategy between the two systems,minimizing the total system load loss cost and repair *** addition,a bi-directional gas flow model is used to describe the natural gas system,which can provide the RIENGS with more flexibility for load restoration during natural gas system ***,the effectiveness of the proposed approach is verified by conducting case studies on the test systems RIENGS E13-G7 and RIENGS E123-G20.

关键词： Resilience regional integrated electricity-natural gas system load restoration repair strategy