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Application of ^(18)F-fluorodeoxyglucose positron emission tomography/computed tomography imaging in recurrent anastomotic tumors after surgery in digestive tract tumors

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2474-2483页

作者： Deng-Feng Ge Hao Ren zi-chen yang Shou-Xiang Zhao Zhen-Ting cheng Da-Da Wu Bin Zhang Department of Cardiothoracic Surgery Nanjing University of Chinese MedicineNanjing 210023Jiangsu ProvinceChina Department of Gastrointestinal Surgery Shanghai Sixth People’s HospitalShanghai 250063China

BACKGROUND This study was to investigate the application value of whole-body dynamic ^(18)F-fluorodeoxyglucose(FDG)positron emission tomography/computed tomogra-phy(PET/CT)imaging in recurrent anastomotic tumors of digestive tract after gastric and esophageal cancer *** patients with gastric and esophageal cancer have a high risk of tumor recurrence,and traditional imaging methods have certain limitations in early detection of recurrent ***-body dynamic ^(18)F-FDG PET/CT imaging,due to its high sensitivity and specifi-city,can provide comprehensive information on tumor metabolic activity,which is expected to improve the early diagnosis rate of postoperative recurrent tumors,and provide an important reference for clinical treatment *** A retrospective analysis was performed on 53 patients with upper digestive tract tumors after operation and systemic dynamic ^(18)F-FDG PET/CT imaging indi-cating abnormal FDG uptake by anastomosis,including 29 cases of gastric cancer and 24 cases of esophageal *** to the follow-up results of gas-troscopy and other imaging examinations before and after PET/CT examination,the patients were divided into an anastomotic recurrence group and anastomotic inflammation *** multi-parameter analysis software was used to obtain the metabolic rate(MRFDG),volume of distribution maximum(DVmax)of anastomotic lesions,and MRmean and DVmean of normal liver *** lesion/background ratio(LBR)was calculated by dividing the MRFDG and DVmax of the anastomotic lesion by the MRmean and DVmean of the normal liver tissue,respectively,to obtain LBR-MRFDG and *** independent sample t test was used for statistical analysis,and a receiver operating characteristic curve was used to analyze the differential diagnostic efficacy of each parameter for anastomotic recurrence and *** The dynamic ^(18)F-FDG PET/CT imaging parameters MRFDG,DVmax,LBR-MRFDG,and LBR-DVmax of post

关键词： Gastric cancer Esophageal cancer Anastomosis Dynamic positron emission tomography Differential diagnosis Metabolic rate

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Estimation of Attractive Regions of Nonlinear MPC Controller-A Feasible Solution-based Method

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信息与控制 2007年第2期36卷 192-198页

作者： WANG zi-yang WU Gang chen Wei Department of Automation University of Science and Technology of China Hefei 230027 China

A new model predictive control(MPC) algorithm for nonlinear systems is presented,its stabilizing property is proved,and its attractive regions are *** presented method is based on the feasible solution,which makes the... 详细信息

关键词：非线性控制 NMPC 吸引区域可行性 MPC控制

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Protective effect of Liangxue Huayu decoction on human retinal pigment epithelial cell(ARPE-19)injury induced by hypoxia through autophagy pathway

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Pharmacology Discovery 2024年第1期4卷 44-50页

作者： Han-Ran Zheng Yi-Tong Lin Sheng chen zi-yang chen Jun-Chang Cao Zhao-Da Ye Yan-Hong Hu College of graduate Fujian University of Traditional Chinese MedicineFujian 350122China Department of Ophthalmology The Second People's Hospital Affiliated to Fujian University of Traditional Chinese MedicineFujian 350003China Comprehensive Outpatient Department Fujian Academy of Traditional Chinese Medicine SciencesFujian 350003China

Background:Exploring the protective mechanism of the Liangxue Huayu(LXHY)decoction on human retinal pigment epithelial(RPE)cells induced by hypoxia through the autophagy ***:The appropriate LXHY decoction concentration was determined by ***-19 cells were divided into the normal control group(A group),CoCl_(2)group(B group),3-Methyladenine(3-MA)group(treated with 3-MA(the inhibition of autophagy pathway))(C group),blank serum(BS)group(D group),LXHY drug-contained serum(DCS)group(E group),and Rapamycin(RAP)group[treated with LXHY drug-contained serum combined with rapamycin group(the activation of autophagy pathway)](F group).Counting the number of autophagosomes and autolysosomes in each group of cells under transmission electron *** infection of cells in each group by mRFP-GFP-LC3 fusion protein adenovirus,the strength of autophagic flux was *** mRNA expression levels of LC3 and Beclin-1 were detected by ***:CCK-8 assay results showed that LXHY DCS could inhibit the cell proliferation of ARPE-19 under hypoxia(all P<0.05).As the transmission electron microscopy assay result showed,compared with the normal control group,the number of autolysosomes was significantly increased in the CoCl_(2)group(P<0.05).Compared with CoCl_(2)group,the number of autolysosomes was significantly reduced the 3-Methyladenine group,blank serum group and LXHY drug-contained serum group(all P<0.001).As autophagic flux assay result showed,compared with the normal control group,the level of autophagosomes and autolysosomes were significantly risen in CoCl_(2)group(all P<0.001).Compared with the CoCl_(2)group,the level of autophagosomes and autolysosomes were significantly fell down in 3-Methyladenine group,blank serum group and LXHY drug-contained serum group(all P<0.05).The level of autolysosomes in the LXHY drug-contained serum group was lower than in the blank serum group(P<0.05).Compared with the LXHY drug-contained serum group,the levels o

关键词： Liangxue Huayu decoction age-related macular degeneration autophagy lysosome autophagosomes

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A V-Folded Digital Laser for On-Demand Vortex Beams by Astigmatic Transformation of Hermite–Gaussian Modes

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Chinese Physics Letters 2019年第12期36卷 32-35页

作者： Sen-Sen Liu Xu-Dong chen Ji-Xiong Pu Zhi-Li Lin zi-yang chen Fujian Key Laboratory of Light Propagation and Transformation College of Information Science and EngineeringHuaqiao UniversityXiamen 361021

A V-folded digital laser using a spatial light modulator(SLM)for intra-cavity loss shaping is exploited to generate Hermite-Gaussian modes with on-demand mode *** aπ/2 astigmatic mode converter,vortex beams carrying on-demand orbital angular momentum(OAM)with a tunable range from-11h to 12 h are *** mode order of the HG mode,hence the OAM of the vortex beam,is digitally switched by changing the phase pattern imposed on the SLM without requiring any mechanic alignment of the *** work has great potential applications in various OAM-tunable vortex beams.

关键词： tunable modulator switched

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Vanadium nitride nanoparticles embedded in carbon matrix with pseudocapacitive behavior for high performance lithium-ion capacitors

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Rare Metals 2022年第7期41卷 2460-2469页

作者： Jin-Hui Zhang zi-yang chen Tie-Zhu Xu Liu-Feng Ai Ying-Hong Xu Xiao-Gang Zhang Lai-Fa Shen Jiangsu Key Laboratory of Electrochemical Energy Storage Technologies College of Material Science and TechnologyNanjing University of Aeronautics and AstronauticsNanjing 210016China

Lithium-ion capacitors(LICs)have attracted wide attention due to their potential of achieving merits of high-power output as well as high energy ***-ever,the key issue of kinetics mismatch between anode and cathode hinders the electrochemical performance of ***,a vanadium nitride composite with nanoparti-cles embedded in carbon matrix(VN-C)was prepared as an efficiently pseudocapacitive anode material with high electronic conductivity and fast Li-ion diffusion *** VN-C composites were synthesized through one-step ammonia heating treatment at different temperatures among which the sample annealed at 600℃exhibits high specific capacity(513 mAh·g^(-1)at 0.1 A·g^(-1)),outstanding rate performance(~300 mAh·g^(-1)at 10 A·g^(-1)),and excellent cyclic steadiness(negligible capacity decay over 2000 cycles)in half-cell devices.A high-performance lithium-ion capacitor device was also fabricated by using VN-C-600 as the anode and activated carbon as the cath-ode,delivering a maximum energy density of 112.6 Wh·kg^(-1)and an extreme power density of 10 kW·kg^(-1).

关键词： Vanadium nitride Carbon matrix Pseudocapacitive behavior Lithium-ion capacitor

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Production induced fracture closure of deep shale gas well under thermo-hydro-mechanical conditions

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Petroleum Science 2024年第3期21卷 1796-1813页

作者： Shi-Ming Wei yang Xia Yan Jin Xu-yang Guo Jing-Yu zi Kai-Xuan Qiu Si-Yuan chen College of Science China University of Petroleum(Beijing)Beijing102249China CNOOC Research Institute Ltd Beijing100028China The University of Hong Kong Hong Kong999077China

Deep shale gas reservoirs have geological characteristics of high temperature,high pressure,high stress,and inferior ability to pass through *** multi-stage fractured horizontal well is the key to exploiting the deep shale gas ***,during the production process,the effectiveness of the hydraulic fracture network decreases with the closure of fractures,which accelerates the decline of shale gas *** this paper,we addressed the problems of unclear fracture closure mechanisms and low accuracy of shale gas production prediction during deep shale gas *** we established the fluid—solid—heat coupled model coupling the deformation and fluid flow among the fracture surface,proppant and the shale *** the fluid—solid—heat coupled model was applied to the fracture network,it was well solved by our numerical method named discontinuous discrete fracture *** with the conventional discrete fracture method,the discontinuous discrete fracture method can describe the three-dimensional morphology of the fracture while considering the effect of the change of fracture surface permeation coefficient on the coupled fracture—matrix flow and describing the displacement discontinuity across the *** simulations revealed that the degree of fracture closure increases as the production time proceeds,and the degree of closure of the secondary fractures is higher than that of the primary *** creep and proppant embedment both increase the degree of fracture *** reduction in fracture surface permeability due to proppant embedment reduces the rate of fluid transfer between matrix and fracture,which has often been overlooked in the ***,it significantly impacts shale gas production,with calculations showing a 24.7%cumulative three-year yield *** study is helpful to understand the mechanism of hydraulic fracture ***,it provides the theoretical guidance for maintaining the long

关键词： Shalegas Fracture closure Fluid-solid-heat coupling Discontinuous discrete fracture

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Multistage Microstructured Ionic Skin for Real-Time Vital Signs Monitoring and Human-Machine Interaction

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ENERGY & ENVIRONMENTAL MATERIALS 2024年第6期7卷 218-229页

作者： Wang, Xueke zi, Jinyu chen, Yi Wu, Qiang Xiang, Zhimin Tu, Yongqiang yang, Peng Wan, Yanfen Yunnan Univ Sch Mat & Energy Natl Ctr Int Res Photoelect & Energy Mat Yunnan Key Lab Electromagnet Mat & DevicesYunnan Kunming 650091 Peoples R China

Skin-like electronics research aiming to mimic even surpass human-like specific tactile cognition by operating perception-to-cognition-to-feedback of stimulus to build intelligent cognition systems for certain imperceptible or inappreciable signals was so attractive. Herein, we constructed an all-in-one tri-modal pressure sensing wearable device to address the issue of power supply by integrating multistage microstructured ionic skin (MM i-skin) and thermoelectric self-power staffs, which exhibits high sensitivity simultaneously. The MM i-skin with multi-stage "interlocked" configurations achieved precise recognition of subtle signals, where the sensitivity reached up to 3.95 kPa-1, as well as response time of 46 ms, cyclic stability (over 1500 cycles), a wide detection range of 0-200 kPa. Furthermore, we developed the thermoelectricity nanogenerator, piezoelectricity nanogenerator, and piezocapacitive sensing as an integrated tri-modal pressure sensing, denoted as P-iskin, T-iskin, and C-iskin, respectively. This multifunctional ionic skin enables real-time monitoring of weak body signals, rehab guidance, and robotic motion recognition, demonstrating potential for Internet of things (IoT) applications involving the artificial intelligence-motivated sapiential healthcare Internet (SHI) and widely distributed human-machine interaction (HMI). Inspired by the multi-level interlocking structure in human skin, the microlevel multi-stage "interlocked" configuration ionic skin is prepared by the bio-template method, and an all-in-one tri-modal pressure sensing wearable device was constructed by integrating thermoelectricity nanogenerator, piezoelectricity nanogenerator, and piezocapacitive sensing, which demonstrates the potential for addressing the issue of power supply and Internet of things applications. image

关键词： bio-template method integrated device ionic skin skin-like microstructure tri-modal pressure sensing PRESSURE SENSOR FILMS PVDF

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Geometric edge effect on the interface of Au/CeO_(2)nanocatalysts for CO oxidation

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Nano Research 2024年第6期17卷 4986-4993页

作者： Hongpeng LiuZhongliang Cao Siyuan yang Qingye Ren Zejian Dong Wei Liu zi-An Li Xing chen Langli Luo Institute of Molecular Plus Tianjin UniversityTianjin 300072China Dalian National Laboratory for Clean Energy Dalian Institute of Chemical Physics(DICP)Chinese Academy of SciencesDalian 116023China State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite Structures and School of Physical Science and TechnologyGuangxi UniversityNanning 530004China Haihe Laboratory of Sustainable Chemical Transformations Tianjin 300192China

The oxide supports play a crucial role in anchoring and promoting the active metal species by geometric confinement and chemical *** design and synthesis of the well-defined oxide support with specific morphology such as size,shape,and exposed facets have attracted extensive research efforts,which directly reflects on their catalytic *** this study,using an Au/CeO_(2)-nanorod model catalyst,we demonstrate an edge effect on the Au/CeO_(2)interfacial structure,which shows a prominent effect on the structure-performance relationship in the CO oxidation *** specific“edge-interface”structure features an“edge-on”Au nanoparticles position on rod-shaped CeO_(2)support,confirmed by atomic-scale electron microscopy characterization,which introduces additional degrees of freedom in coordination environment,chemical state,bond length,and *** with theocratical calculations and in situ diffuse reflectance infrared Fourier transform spectroscopy(DRIFTS)investigations,we confirmed that this“edge-interface”has distinct adsorption properties due to the change of O vacancy formation energy as well as the chemical states of Au resulting from the electron transfer and redistribution between the metal and the *** results demonstrate a non-conventional geometric effect of rod-shaped supported metal catalysts on the catalytic performance,which could provide insights into the atomic-precise utilization of catalysts.

关键词： ceria nanorod supported catalyst edge-effect atomic scale

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Surgical treatment of an old avulsion fracture of the ischial tuberosity and ischial ramus: A case report

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World Journal of Orthopedics 2024年第1期15卷 94-100页

作者： zi-Ru chen Shi-Jie Liao Fu-Chun yang Department of Orthopedic Trauma and Hand Surgery The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina

BACKGROUND Avulsion fracture of the ischial tuberosity is a relatively clinically rare type of trauma that is mainly incurred by adolescents during competitive sports *** to previous literature,the most commonly involved sports are soccer,sprinting,and gymnastics,in descending ***-induced avulsion fracture of the ischial tuberosity and ischial ramus is extremely clinically *** SUMMARY A case of a neglected avulsion fracture of the ischial tuberosity and ischial ramus was diagnosed in a young female dancer who complained of pain and restricted movement of her right *** stated that she had suffered the injury while performing a split leap during a dance performance 9 mo ***,she underwent surgery and obtained satisfactory treatment *** Early diagnosis of these fractures is important to ensuring early proper treatment towards a quicker *** old fractures with nonunion and chronic buttock pain,surgery is a preferred therapeutic choice with good treatment outcomes.

关键词： Ischial tuberosity Ischial ramus Avulsion fracture Delayed diagnosis Splitleap injury Case report

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Chain Dynamics Heterogeneity in Plasticized Poly(vinyl butyral)(PVB) as Elucidated by Solid-State NMR

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Chinese Journal of Polymer Science 2024年第1期42卷 113-124,I0010页

作者： Jing Lv Xu chen zi-Shuo Wu Ya-Hui Li Wei chen National Synchrotron Radiation Laboratory Anhui Provincial Engineering Laboratory of Advanced Functional Polymer FilmCAS Key Laboratory of Soft Matter ChemistryUniversity of Scienceand Technology of ChinaHefei 230026China

The chain dynamics heterogeneity of the poly(vinyl butyral)(PVB) plasticized by triethylene glycol bis(2-ethylhexa noate)(TEG-EH) was investigated by various solid-state NMR *** plasticized PVB shows two domains in distinct molecular dynamics differences,namely,rigid and soft domains,where the latter is the plasticizer-rich *** time domain low field NMR was first used to investigate the dynamics heterogeneity of the plasticized PVB,and the results show the decreasing activated energy of components in the soft domain of plasticized PVB(E_a=20.2 kJ/mol) as compared with that of the pristine one(E_a=24.3 kJ/mol).Detailed dynamics heterogeneity was obtained by high-field NMR with site-specific *** quadrupole-echo ~2H-NMR was adopted to elucidate the dynamics heterogeneity of the vinyl alcohol(VA) units,where only the hydroxyl group of VA is *** ~1H-^(13)C WISE NMR spectra show that there is not much difference in the mobility of the VB unit in PVB with and without plasticizer,whereas the glass transition temperature differed by approximately 53℃.This is further supported by Torchia's T_1 relaxation *** origin of such an unusual phenomenon is attributed to the critical role of the remaining VA(~22%) in the soft domain,where the VA units locally aggregate through hydrogen ***,the existence of a mobility gradient in the VB unit has been ***,the mobility difference for VB with different stereo-geometry(meso or racemic conformation) is observed for the first *** indicates the importance of modulating the ratio of meso over racemic VB for controlling the macroscopic perfo rmance of PVB.

关键词： Poly(vinyl butyral) Dynamics heterogeneity Plasticizer Solid state NMR

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