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Bilateral lung transplantation,a new option for pulmonary metastasis from hepatocellular carcinoma?

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Hepatobiliary & Pancreatic Diseases International 2023年第1期22卷 96-98页

作者： zi-tao wang Jing-Yu Chen Department of Thoracic Surgery Wuxi Lung Transplant CenterWuxi People’s Hospital Affiliated to Nanjing Medical UniversityWuxi 214023China Department of Lung Transplant the Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China

To the Editor:The lung is the most frequent site of extrahepatic hepatocellular carcinoma(HCC)recurrence after liver transplantation(LT).Pulmonary metastasis from hepatocellular carcinoma(PM-HCC)carries a poor prognosis as the patient could finally die of pulmonary failure secondary to the tumor despite maintaining ideal liver function.

关键词： metastasis hepatocellular lung

Source apportionment of river water pollution in a typical agricultural city of Anhui Province, eastern China using multivariate statistical techniques with APCS– MLR

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Water Science and Engineering 2023年第2期16卷 165-174页

作者： Kai Chen Qi-meng Liu Wei-hua Peng Yu Liu zi-tao wang State Key Laboratory of Mining Response and Disaster Prevention and Control in Deep Coal Mine Huainan 232001China School of Earth and Environment Anhui University of Science&TechnologyHuainan 232001China Key Laboratory of Mine Water Resource Utilization of Anhui Higher Education Institutes Suzhou UniversitySuzhou 234000China Qinghai Institute of Salt Lakes Chinese Academy of SciencesXining 810008China

The deterioration of the surface water environment has become a serious challenge for water resources management due to increasing anthropogenic disturbance. Water resources protection requires control of potential pollution sources. In this study, 99 water samples were collected from a river in a typical agricultural city of Anhui Province in eastern China, and these samples were analyzed in terms of pH, electrical conductivity, and the concentrations of F-, Cl-, SO42-, Na+, K+, Mg2+, Ca2+, As, Cr, Cu, Zn, and Pb. Cluster analysis, co-occurrence network analysis, and principal component analysis/factor analysis were conducted to qualitatively identify the potential sources of river water pollution in the study area. An absolute principal component score-multiple linear regression receptor model was used to quantitatively evaluate the contribution of each source to water quality parameters. The results showed that all observed water quality indices met the quality criteria specified in the Chinese drinking water standards, except for pH, ρ(F-), ρ(SO42-), and ρ(As). The heat map showed that the frequent recharge of pollutants from the tributaries during the wet season was the main reason for the deterioration of water quality. Five sources of river water pollution were identified, and their contribution ratios in a descending order were as follows: the geogenic process (24%) > agricultural activities (21%) > poultry farming sources (17%) > domestic pollution (9%) > transportation pollution (5%). Therefore, controlling pollution from agricultural activities, strengthening the regulation of livestock farming, and improving the sewage network are the recommended strategies for improving the quality of surface water resources in this area.

关键词： Surface water Water quality Source apportionment APCS-MLR model Huaihe river basin

Research advances in smart responsive-hydrogel dressings with potential clinical diabetic wound healing properties

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Military Medical Research 2024年第4期11卷 543-566页

作者： Ying Chen Xing wang Sheng tao Qi wang Pan-Qin Ma zi-Biao Li Yun-Long Wu Da-Wei Li Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology School of Pharmaceutical SciencesXiamen UniversityXiamen 361102FujianChina Beijing National Laboratory for Molecular Sciences Institute of ChemistryChinese Academy of SciencesBeijing 100090China University of Chinese Academy of Sciences Beijing 100049China Senior Department of Orthopedics the Fourth Medical Center of Chinese PLA General HospitalBeijing 100091China Institute of Materials Research and Engineering A*STAR(Agency for ScienceTechnology and Research)Singapore 138634Singapore

The treatment of chronic and non-healing wounds in diabetic patients remains a major medical *** reports have shown that hydrogel wound dressings might be an effective strategy for treating diabetic wounds due to their excellent hydrophilicity,good drug-loading ability and sustained drug release *** a typical example,hyaluronic acid dressing(Healoderm)has been demonstrated in clinical trials to improve wound-healing efficiency and healing rates for diabetic foot ***,the drug release and degradation behavior of clinically-used hydrogel wound dressings cannot be adjusted according to the wound *** to the intricacy of diabetic wounds,antibiotics and other medications are frequently combined with hydrogel dressings in clinical practice,although these medications are easily hindered by the hostile *** this case,scientists have created responsive-hydrogel dressings based on the microenvironment features of diabetic wounds(such as high glucose and low pH)or combined with external stimuli(such as light or magnetic field)to achieve controllable drug release,gel degradation,and microenvironment improvements in order to overcome these clinical *** responsive-hydrogel dressings are anticipated to play a significant role in diabetic therapeutic wound ***,we review recent advances on responsive-hydrogel dressings towards diabetic wound healing,with focus on hydrogel structure design,the principle of responsiveness,and the behavior of *** but not least,the advantages and limitations of these responsive-hydrogels in clinical applications will also be *** hope that this review will contribute to furthering progress on hydrogels as an improved dressing for diabetic wound healing and practical clinical application.

关键词： Responsive-hydrogel Diabetic wound Anti-inflammation Tissue remodeling

A generalization of Banach's lemma and its applications to perturbations of bounded linear operators

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Applied Mathematics(A Journal of Chinese Universities) 2024年第2期39卷 363-369页

作者： wang zi DING Jiu wang Yu-wen School of Mathematics Sciences Harbin Normal UniversityHarbin 150025China School of Mathematics and Natural Sciences The University of Southern MississippiHattiesburg MS 39406-5043USA Academic Committee Harbin Institute of PetroleumHarbin 150027China

Let X be a Banach space and let P:X→X be a bounded linear *** an algebraic inequality on the spectrum of P,we give a new sufficient condition that guarantees the existence of(I-P)^(-1) as a bounded linear operator on X,and a bound on its spectral radius is also *** generalizes the classic Banach *** apply the result to the perturbation analysis of general bounded linear operators on X with commutative perturbations.

关键词： Banach lemma spectral radius generalized inverse perturbation analysis

The SLEGS beamline of SSRF

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Nuclear Science and Techniques 2024年第7期35卷 20-30页

作者： Long-Xiang Liu Hong-Wei wang Gong-tao Fan Hang-Hua Xu Yue Zhang zi-Rui Hao Ai-Guo Li Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai201210China

The Shanghai Laser Electron Gamma Source(SLEGS, located in BL03SSID) beamline at the Shanghai Synchrotron Radiation Facility(SSRF) is a Laser Compton Scattering(LCS) gamma source used for the investigation of nuclear structure, which is in extensive demand in fields such as nuclear astrophysics, nuclear cluster structure, polarization physics, and nuclear energy. The beamline is based on the inverse Compton scattering of 10640 nm photons on 3.5 GeV electrons and a gamma source with variable energy by changing the scattering angle from 20° to 160°. γ rays of 0.25-21.1 MeV can be extracted by the scheme consisting of the interaction chamber, coarse collimator, fine collimator, and attenuator. The maximum photon flux for 180° is approximately 10~7 photons/s at the target at 21.7 MeV, with a 3-mm-diameter beam. The beamline was equipped with four types of spectrometers for experiments in( γ,γ'),( γ,n),( γ,p), and( γ,α). At present, Nuclear Resonance Fluorescence(NRF) spectrometry, Flat-Efficiency neutron Detector(FED) spectrometry, neutron Time-Of-Flight(TOF) spectrometry, and Light-Charged Particle(LCP) spectrometry methods have been developed.

关键词： Shanghai Synchrotron Radiation Facility SLEGS Nuclear astrophysics Nuclear structure

Gas-surface interaction features under effects of gas-gas molecules interaction in high-speed flows

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Chinese Journal of Aeronautics 2024年第5期37卷 228-242页

作者： Ruiling tao Zhihui wang School of Engineering Science University of Chinese Academy of SciencesBeijing 100049China

Understanding interactions between gas molecules and solid surface is key to the aerodynamic design of high-speed,high-altitude aerospace vehicles,but there is a large dispersion of gas-surface interaction parameters or namely accommodation *** uncertainty results partly from different considerations of the interaction between gas molecules in various experimental and numerical *** this study,effects of gas-gas molecules interaction are systematically discussed by comparing two different approaches of molecular dynamics simulation of high-speed argon molecules scattering on a graphite *** popularly-used“single scattering”approach repeats the scattering process of a single gas molecule without considering the gas-gas molecules *** newly-developed“continual scattering”approach continually shoots gas molecules at the surface,considering collisions between gas molecules in addition to gas molecules’collisions with ***-surface interaction features in the two approaches are compared and discussed under various affecting factors including rarefaction degree,gas-surface interaction strength,surface temperature and incident *** is shown that these two approaches usually produce different accommodation coefficients,and the corresponding mechanisms are *** study could help clarify some doubts about the selection of accommodation coefficients in engineering practice,and also provide an instruction on design of an appropriate molecular dynamics simulation approach.

关键词： Gas-surface interaction Molecular dynamics Accommodation coefficient Aerospace vehicles High-speed flow

Atomically dispersed materials:Ideal catalysts in atomic era

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Nano Research 2024年第1期17卷 18-38页

作者： tao Gan Dingsheng wang Department of Chemistry Tsinghua UniversityBeijing 100084China

Catalysts can accelerate the chemical reaction rate and effectively promote the molecules transformation,which is of great significance in the research of chemical industry and material *** extreme utilization of reactive sites has led to the emergence and development of atomically dispersed materials(ADMs).The highly active coordination unsaturated metal sites and fully utilized metal atoms make ADMs show great potential in catalytic *** adjustment of coordination environment and electronic structure provides more possibilities for constructing reactive centers with different *** review summarized the application and research progress of ADMs in different *** design strategy and structure–activity relationship of ADMs for specific reactions were summarized and ***,we also provided advices for the challenges and opportunities faced by ADMs in catalytic reactions.

关键词： atomically dispersed materials catalysis organic synthesis battery sensor enzyme

Semi-supervised remote sensing image scene classification with prototype-based consistency

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Chinese Journal of Aeronautics 2024年第2期37卷 459-470页

作者： Yang LI Zhang LI zi wang Kun wang Qifeng YU College of Aerospace Science and Engineering National University of Defense TechnologyChangsha 410073China

Deep learning significantly improves the accuracy of remote sensing image scene classification,benefiting from the large-scale ***,annotating the remote sensing images is time-consuming and even tough for *** neural networks trained using a few labeled samples usually generalize less to new unseen *** this paper,we propose a semi-supervised approach for remote sensing image scene classification based on the prototype-based consistency,by exploring massive unlabeled *** this end,we,first,propose a feature enhancement module to extract discriminative *** is achieved by focusing the model on the foreground ***,the prototype-based classifier is introduced to the framework,which is used to acquire consistent feature *** conduct a series of experiments on NWPU-RESISC45 and Aerial Image Dataset(AID).Our method improves the State-Of-The-Art(SOTA)method on NWPU-RESISC45 from 92.03%to 93.08%and on AID from 94.25%to 95.24%in terms of accuracy.

关键词： Semi-supervised learning Remote sensing Scene classification Prototype network Deep learning

Azacitidine maintenance therapy for blastic plasmacytoid dendritic cell neoplasm allograft: A case report

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World Journal of Clinical Cases 2024年第1期12卷 136-141页

作者： Li-Li tao Hui-Ting Wen zi-Yi wang Juan Cheng Li Zhao Department of Hematology The First Clinical Medical CollegeLanzhou UniversityLanzhou 730000Gansu ProvinceChina Department of Hematology The First Hospital of Lanzhou UniversityLanzhou 730000Gansu ProvinceChina

BACKGROUND Blastic plasmacytoid dendritic cell neoplasm(BPDCN)is a rare,highly invasive malignant *** is no universally accepted standard of care because of its rarity and the dearth of prospective *** is still challenging for some patients to achieve persistent clinical remission or cure,despite the success of allogeneic hematopoietic stem cell transplantation(allo-HSCT),indicating that there is still a significant recurrence *** report a case of prevention of BPDCN allograft recurrence by azacitidine maintenance therapy and review the relevant *** SUMMARY We report a 41-year-old man with BPDCN who was admitted to hospital due to skin sclerosis for>5 mo’*** was diagnosed by combined clinical assessment and laboratory *** diagnosis,the patients underwent induction consolidation chemotherapy to achieve the first complete remission,followed by bridging ***-transplantation,azacitidine(75 mg/m2 for 7 d)was administered as maintenance therapy,with repeat administration every 4–6 wk and appropriate extension of the chemotherapy *** 10 cycles,the patient has been disease free for 26 mo after *** assessments of bone marrow morphology,minimal residual disease,full donor chimerism,Epstein–Barr virus,and cytomegalovirus all yielded normal results with no abnormalities *** Azacitidine may be a safe and effective maintenance treatment for BPDCN following transplantation because there were no overt adverse events during the course of treatment.

关键词： Blastic plasmacytoid dendritic cell neoplasm Azacitidine Allogeneic hematopoietic stem cell transplantation Maintenance therapy Case report