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Bullous pemphigoid associated with acquired hemophilia A: A case report

World Journal of Clinical Cases 2025年第4期13卷 28-33页

作者： Su-Ye Hu Meng-Can Li zi-Jia hao Xu-Ya Chai Pei-Sai Li Yang Liu Li-Xia Liu Ying Xu Pan-Pan Yang Ling-E Li Department of Dermatology Shijiazhuang Traditional Chinese Medicine HospitalShijiazhuang 050051Hebei ProvinceChina Graduate School Hebei University of Traditional Chinese MedicineShijiazhuang 050051Hebei ProvinceChina Department of Pathology Shijiazhuang Traditional Chinese Medicine HospitalShijiazhuang 050051Hebei ProvinceChina

BACKGROUND Acquired hemophilia A (AHA) is a rare and potentially severe bleeding disordercaused by circulating autoantibodies against factor Ⅷ (FⅧ). In approximately50% of the patients, the condition is associated with autoimmune diseases,cancers, medication use, pregnancy, and the post-partum period. Bullous pemphigoid(BP) is a chronic autoimmune subepidermal blistering disease associatedwith tissue-bound and circulating autoantibodies against BP antigens 180 (BP180)and 230 (BP230). AHA-associated BP has a high mortality rate;hence, the understandingof this disease must *** SUMMARY A 69-year-old man presented with erythema, blisters, blood blisters, and crustsaccompanied by severe pruritus for more than 20 days, and ecchymosis andswelling on his left upper arm for 3 days. Pathological examination revealed asubepidermal blister that contained eosinophils. Laboratory tests showed that theBP180 autoantibody levels had increased, isolated activated partial thromboplastintime was notably prolonged (115.6 s), and coagulation FⅧ activity wasextremely low (< 1.0%). Furthermore, the FⅧ inhibitor titer had greatlyincreased (59.2 Bethesda units). Therefore, the patient was diagnosed as having BP associated with AHA, prescribed 0.05% topical halometasone cream, and transferred to a higher-level hospitalfor effective treatment;however, he died after 2 *** AHA associated BP is rare, dangerous, and has a high mortality rate. Therefore, its timely diagnosis and effectivetreatment are necessary.

关键词： Bullous pemphigoid Acquired hemophilia A Acquired hemophilia A FactorⅧ Case report

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Borderline Case of Traces and Extensions for Weighted Sobolev Spaces

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Acta Mathematica Sinica,English Series 2023年第9期39卷 1817-1833页

作者： Man zi huang Xian Tao Wang Zhuang Wang Zhi hao Xu MOE-LCSM School of Mathematics and StatisticsHunan Normal UniversityChangsha410081P.R.China

In this paper,we study the traces and the extensions for weighted Sobolev spaces on upper half spaces when the weights reach to the borderline *** first give a full characterization of the existence of trace spaces for these weighted Sobolev spaces,and then study the trace parts and the extension parts between the weighted Sobolev spaces and a new kind of Besov-type spaces(on hyperplanes)which are defined by using integral averages over selected layers of dyadic cubes.

关键词： Sobolev space borderline case trace theorem Besov-type space Muckenhoupt A_p weight

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Kleptomania:Recent Advances in Symptoms,Etiology and Treatment

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Current Medical Science 2018年第5期38卷 937-940页

作者： zi-hao ZHANG Fu-rong huang Deng-hua LIU Criminal Justice School Zhongnan.University of Economics and Law Wuhan 430073China Literature School Hubei University of Education Wuhan 430205China Departmentof Neurology and Psychiatry Tongji Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Kleptomania is a kind of uncontrollable impulse and behavior of stealing,and it is also a serious *** present,studies on pathological theft at home and abroad are not sufficient,and the understanding of the symptoms,etiology and treatment of this disease is very *** article focuses on the latest development of symptoms, etiology and treatment of kleptomania,providing a reference for people to further identify, treat and study the disease.

关键词： kleptomania symptoms etiology treatment

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Bumblebees with the socially transmitted microbiome:A novel model organism for gut microbiota research

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Insect Science 2022年第4期29卷 958-976页

作者： zi-Jing Zhang hao Zheng College of Food Science and Nutritional Engineering China Agricultural UniversityBeijingChina

Eusocial bumble and honey bees are important pollinators for global ecology and the agricultural *** both the bumble and honey bees possess similar and host-restricted gut microbiota,they differ in aspects of morphology,autonomy,physiology,behavior,and life *** social bee gut bacteria exhibit host specificity that is likely a result of long-term *** unique life cycle of bumblebees is key for the acquisition and development of their gut microbiota,and affects the strain-level diversity of the core bacterial *** on bumblebee gut bacteria show that they retain less functional capacity for carbohydrate metabolism compared with that of the *** discuss the potential roles of the bumblebee gut microbiota against pathogenic threats and the application of host-specific probiotics for *** the advantages of the bumblebee microbiome,including the simple structure and host specificity,and the ease of manipulating bumblebee colonies,we propose that bumblebees may provide a valuable system for understanding the general principles of host-microbe interactions,gut-brain axis,and vertical transmission.

关键词： bumblebee gut microbiota host-microbe interaction model organism

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Harmonia: Explicit Congestion Notification and Credit-Reservation Transport Converged Congestion Control in Datacenters

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Journal of Computer Science & Technology 2021年第5期36卷 1071-1086页

作者： Ding-huang Hu De-Zun Dong Yang Bai Shan huang Ze-Jia Zhou zi-hao Wei Xiang-Ke Liao College of Computer Science and Technology National University of Defense TechnologyChangsha 410073China

Bursty traffic and thousands of concurrent flows incur inevitable network congestion in datacenter networks(DCNs)and then affect the overall *** transport protocols are developed to mitigate the network congestion,including reactive and proactive *** schemes use different congestion signals,such as explicit congestion notification(ECN)and round trip time(RTT),to handle the network congestion after congestion ***,with the growth of scale and link speed in datacenters,reactive schemes encounter a significant problem of slow responding to *** the contrary,proactive protocols(e.g.,credit-reservation protocols)are designed to avoid congestion before it occurs,and they have the advantages of zero data loss,fast convergence and low buffer *** credit-reservation protocols have not been widely deployed in current DCNs(e.g.,Microsoft,Amazon),which mainly deploy ECN-based protocols,such as data center transport control protocol(DCTCP)and data center quantized congestion notification(DCQCN).And in an actual deployment scenario,it is hard to guarantee one protocol to be deployed in every server at one *** credit-reservation protocol is deployed to DCNs step by step,the network will be converted to multi-protocol state and will face the following fundamental challenges:1)unfairness,2)high buffer occupancy,and 3)heavy tail ***,we propose Harmonia,aiming for converging ECN-based and credit-reservation protocols to fairness with minimal *** the best of our knowledge,Harmonia is the first to address the trouble of harmonizing proactive and reactive congestion *** the common ECN-based protocols-DCTCP and DCQCN,Harmonia leverages forward ECN and RTT to deliver real-time congestion information and redefines feedback *** the evaluation,the results show that Harmonia effectively solves the unfair link allocation,eliminating the timeouts and addressing the buffer overflow.

关键词： datacenter credit-reservation protocol ECN-based(explicit congestion notification based)protocol multiprotocol converging

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喷印金属微滴撞击粗糙表面的分子动力学模拟

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原子与分子物理学报 2025年第4期42卷 73-80页

作者：苏仁健陈小勇游自浩桂林电子科技大学机电工程学院桂林541004 广西制造系统与先进制造技术重点实验室桂林541004

研究金属微滴撞击固体表面的行为对预测微滴形态和实现高精度的喷印制造具有重要的意义.然而,由于微纳尺度下金属微滴撞击实验的难以开展,目前涉及金属微滴撞击粗糙表面的形态变化和热毛细效应机理尚不清楚.本文采用分子动力学模拟研究... 详细信息

研究金属微滴撞击固体表面的行为对预测微滴形态和实现高精度的喷印制造具有重要的意义.然而,由于微纳尺度下金属微滴撞击实验的难以开展,目前涉及金属微滴撞击粗糙表面的形态变化和热毛细效应机理尚不清楚.本文采用分子动力学模拟研究了镓铟微滴撞击粗糙表面的动态行为,定量分析了撞击速度、粗糙结构和不同温度对微滴撞击行为的影响.结果表明:随着撞击速度的提高,微滴先后呈现沉积、弹跳和破碎飞溅三种模式,且微滴的最大铺展因子与韦伯数呈幂函数关系.此外,通过修饰基底粗糙结构发现,结构间距或高度的变化对微滴的弹跳行为存在不同的影响机制,可以有效促使或抑制微滴的弹跳行为.最后,分析得出随着温度的提高,微滴的铺展直径会变大,产生的黏性耗散也会增大.研究结果对金属微滴撞击行为的有效预测提供了理论基础.

关键词：金属微滴撞击粗糙基底分子动力学

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An Overview of Stretchable Supercapacitors Based on Carbon Nanotube and Graphene

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Chinese Journal of Polymer Science 2020年第5期38卷 491-505,I0006页

作者： Wen-Le Ma Zhi-hao Cai Yi Zhang zi-Yuan Wang Lun Xia Su-Ping Ma Guang-hao Li Yi huang National Institute for Advanced Materials Tianjin Key Laboratory of Metal and Molecule Based Material ChemistryKey Laboratory of Functional Polymer MaterialsCollaborative Innovation Center of Chemical Science and Engineering(Tianjin)School of Materials Science and EngineeringNankai UniversityTianjin 300350China Beijing Institute of Aeronautical Materials Beijing 100095China

The wearable demand of modern electronic devices makes flexible and stretchable energy storage device urgently *** and flexible supercapacitors(SCs)are energy storage devices that provide ultrahigh power density while having long-term durability,high security,and electrochemical *** different SCs electrode materials,CNTs and graphene-based materials exhibit great potential in terms of stretchable SCs due to its ultrahigh electrical conductivity,large specific surface area and good mechanical *** this review,the state-of-the-art process and achievements in the field of stretchable SCs enabled by CNTs and graphene are presented,which include the novel design strategy,mechanical and electrochemical *** final section highlights current challenges and future perspectives on research in this thriving field.

关键词： Stretchable Supercapacitors Carbon materials Graphene CNTs

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Spacecraft Doppler tracking with possible violations of LLI and LPI: preliminary bounds on LLI from Mars Express

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Research in Astronomy and Astrophysics 2014年第9期14卷 1201-1206页

作者： Yu-Fei Zhang Xue-zi Zhang Jing-hao Liu Yong huang Yi Xie School of Astronomy and Space Science Nanjing University Shanghai Astronomical Observatory Chinese Academy of Sciences Key Laboratory of Modern Astronomy and Astrophysics Nanjing University Ministry of Education

Three-way spacecraft Doppler tracking is currently widely used and it plays an important role in the control and navigation of deep space missions. Using the theory of three-way Doppler tracking, including possible violations of the local Lorentz invariance （LLI） and the local position invariance （LPI）, we analyze the post-fit residuals of three-way Doppler tracking data of Mars Express. These Doppler observations were carried out from August 7th to 8th in 2009, with an uplink station administered by the European Space Agency at New Norcia in Australia and three downlink stations at Shanghai, Kunming and Urumqi in China. We find that, although these observations impose preliminary bounds on LLI at the level of 10^-2, they are not suitable for testing LPI because of the configuration of these stations and the accuracy of the observations. To our knowledge, this is one of the first attempts in China to apply radio science to the field of fundamental physics.

关键词： space vehicles -- techniques: radial velocities -- gravitation

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Real-time wide-range neutron flux monitor for thorium-based molten salt reactor

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Nuclear Science and Techniques 2018年第8期29卷 107-113页

作者： Xiang Zhou zi-hao Liu Chao Chen Guo-Qing huang Ze-Jie Yin State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Modern Physics University of Science andTechnology of ChinaHefei 230026China Shanghai Institute of Applied Physics Shanghai 201800China

A novel full-digital real-time neutron flux monitor(NFM) has been developed for thorium-based molten salt reactor(TMSR).The system is based on the highspeed,parallel,and pipeline processing of the field programmable gate array as well as the high-stability controller area network platform.A measurement range of 10~8 counts per second is achieved with a single fission chamber by utilizing the normalization of the count and Campbell *** the advantages of using the measurement range,system integrity,and real-time performance,digital NFM has been tested in the Xi'an pulsed reactor fission experiments and was found to exhibit superior experimental performance.

关键词：监视器反应堆流动中子熔融宽范围控制器区域网络实时

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Diversity and functional analysis of Chinese bumblebee gut microbiota reveal the metabolic niche and antibiotic resistance variation of Gilliamella

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Insect Science 2021年第2期28卷 302-314页

作者： zi-Jing Zhang Ming-Fei huang Li-Fei Qiu Rui-hao Song zi-Xuan Zhang Yi-Wen Ding Xin Zhou Xue Zhang hao Zheng College of Food Science and Nutritional Engineering China Agricultural UniversityBeijingChina College of Plant Protection China Agricultural UniversityBeijingChina

Bumblebees play an important role in maintaining the balance of natural and agricultural ecosystems,and the characteristic gut microbiota of bumblebees exhibit significant mutualistic *** has the highest diversity of bumblebees;however,gut microbiota of Chinese bumblebees have mostly been investigated through cultureindependent ***,we analyzed the gut communities of bumblebees from Sichuan,Yunnan,and Shaanxi provinces in China through 16S ribosomal RNA amplicon sequencing and bacterial *** revealed that the bumblebees examined in this study harbored two gut enterotypes as previously reported:one is dominated by Gilliamella and Snodgrassella,and the other is distinguished by prevalent environmental *** gut compositions obviously varied among different individual *** then isolated 325 bacterial strains and the comparative genomic analysis of Gillianiella strains revealed that galactose and pectin digestion pathways were conserved in strains from bumblebees,while genes for the utilization of arabinose,mannose,xylose,and rhamnose were mostly *** two strains from the Chinese bumblebees possess the multidrug-resistant gene emrB,which is phylogenetically closely related to that from the symbionts of soil entomopathogenic *** contrast,tetracycline-resistant genes were uniquely present in three strains from the *** results illustrate the prevalence of strain-level variations in the metabolic potentials and the distributions of antibiotic-resistant genes in Chinese bumblebee gut bacteria.

关键词： antibiotic resistance bumblebee Gilliamella.,gut microbiota sugar metabolism

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