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第二十二届全国心理学学术会议

作者： zi yu hao yuan Zhong Ning Zhang Chun Wang School of Psychology Nanjing Normal University Jiangsu Key Laboratory of Mental Health and Cognitive Science Nanjing Normal University Nanjing Brain Hospital Affiliated to Nanjing Medical University Functional Brain Imaging Institute of Nanjing Medical University Cognitive Behavioral Therapy Institute of Nanjing Medical University

Background: Many studies have found that the hippocampus plays a very important role in major depressive disorder(MDD). The hippocampus can be divided into three subfields: the cornu ammonis(CA), dentate gyrus(DG) and subiculum. Each subfield of the hippocampus has a unique function and are differentially associated with the pathological mechanisms of MDD. However, no research exists to describe the resting state functional connectivity of each hippocampal subfield in MDD. Methods: 55 patients with MDD and 25 healthy controls(HCs) matched for gender, age and years of education were obtained. A seed-based method that imposed a template on the whole brain was used to assess the resting-state functional connectivity(rsFC) of each hippocampal subfield. Results: Patients with MDD demonstrated increased connectivity in the left premotor cortex(PMC) and reduced connectivity in the right insula with the CA seed region. Increased connectivity was reported in the left orbitofrontal cortex(OFC) and left ventrolateral prefrontal cortex(vlPFC) with the DG seed region. The subiculum seed region revealed increased connectivity with the left premotor cortex(PMC), the right middle frontal gyrus(MFG), the left ventrolateral prefrontal cortex(vlPFC) and reduced connectivity with the right insula. ROC curves confirmed that the differences between groups were statistically significant. Conclusion: The results suggest that the CA, DG and subiculum have significant involvement with MDD. Specifically, the abnormal functional connectivity of the CA may be related to bias of coding and integration of information in patients with MDD. The abnormal functional connectivity of the DG may be related to the impairment of working memory in patients with MDD, and the abnormal functional connectivity of the subiculum may be related to cognitive impairment and negative emotions in patients with MDD.

关键词： major depressive disorder hippocampal subfields cornu ammonis dentate gyrus subiculum resting-state functional connectivity

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我国乳腺癌改良根治术后放疗现状的调查分析

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中华放射肿瘤学杂志 2005年第6期14卷 471-475页

作者：惠周光余子豪中国医学科学院中国协和医科大学肿瘤研究所肿瘤医院放疗科北京100021

目的为了全面了解我国目前乳腺癌根治术或改良根治术后放疗(简称术后放疗) 的现状,特开展此项研究.方法对全国所有开展放疗的单位分别于2003年1～3月邮寄调查表 ,对乳腺癌术后放疗的适应证和放疗技术等进行两轮问卷调查. 结果乳腺癌术... 详细信息

目的为了全面了解我国目前乳腺癌根治术或改良根治术后放疗(简称术后放疗) 的现状,特开展此项研究.方法对全国所有开展放疗的单位分别于2003年1～3月邮寄调查表 ,对乳腺癌术后放疗的适应证和放疗技术等进行两轮问卷调查. 结果乳腺癌术后放疗适应证中包含T1～T2期病变及位于内象限或中央区、T1～T2期淋巴结转移1～3个、T3期或淋巴结转移≥4个的单位比例分别为11.9%、63.8%、87.6%和97.1%,其中仅以T3期或淋巴结转移≥4个为术后放疗主要适应证的单位只占7.1%.在放疗靶区中,常规照射锁骨上下区的单位最多, 占96.2%,其余依次为内乳区85.2%、胸壁79.0%和腋窝74.8%.胸壁照射以60Co或高能 X线切线野照射最多见(45.2%),单纯电子线照射占28.3%,60Co或高能X线与电子线混合照射占 25.3%;34.3%的单位在照射中胸壁加垫填充物;胸壁的中位照射剂量是50 Gy(30～60 Gy ).腋窝照射以60Co或高能X线为主(86.6%),与电子线混合照射占12.7%;有65.6%的单位采用腋后野补量照射技术;腋窝中位照射剂量是50 Gy(40～64 Gy).锁骨上下区也以 60Co或高能X线照射为主(61.4%),与电子线混合照射占33.7%;锁骨上下区中位照射剂量是50 Gy(40～ 60 Gy ).内乳区单纯60Co或高能X线照射占49.7%,与电子线混合照射占33.0%,单纯电子线照射占15.6%;内乳区中位照射剂量也是50 Gy(40～60 Gy).结论目前我国对肿瘤≥5 cm 或淋巴结转移≥4个的乳腺癌进行术后放疗的看法比较一致,但对T1～T2期淋巴结转移1～3个的患者是否需要术后放疗的看法尚存分歧,有待进一步的前瞻性临床研究来证实.

关键词：中国乳腺癌改良根治术放射治疗 X线照射照射剂量

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Gradient‑Layered MXene/Hollow Lignin Nanospheres Architecture Design for Flexible and Stretchable Supercapacitors

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Nano-Micro Letters 2025年第2期17卷 447-462页

作者： haonan Zhang Cheng hao Tongtong Fu Dian yu Jane Howe Kaiwen Chen Ning Yan hao Ren Huamin Zhai Jiangsu Provincial Key Lab of Sustainable Pulp and Paper Technology and Biomass Materials NanJing Forestry UniversityNanjing 210037People’s Republic of China Department of Chemical Engineering and Applied Chemistry University of Toronto200 College StreetTorontoON M5S 3E5Canada Department of Materials Science and Engineering University of Toronto184 College StreetTorontoON M5S 3E4Canada College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037People’s Republic of China

With the rapid development of flexible wearable electronics,the demand for stretchable energy storage devices has *** this work,a novel gradient-layered architecture was design based on single-pore hollow lignin nanospheres(HLNPs)-intercalated two-dimensional transition metal carbide(Ti_(3)C_(2)T_(x) MXene)for fabricating highly stretchable and durable *** depositing and inserting HLNPs in the MXene layers with a bottom-up decreasing gradient,a multilayered porous MXene structure with smooth ion channels was constructed by reducing the overstacking of MXene ***,the micro-chamber architecture of thin-walled lignin nanospheres effectively extended the contact area between lignin and MXene to improve ion and electron accessibility,thus better utilizing the pseudocapacitive property of *** these strategies effectively enhanced the capacitive performance of the *** addition,HLNPs,which acted as a protective phase for MXene layer,enhanced mechanical properties of the wrinkled stretchable electrodes by releasing stress through slip and deformation during the stretch-release cycling and greatly improved the structural integrity and capacitive stability of the *** electrodes and symmetric flexible all-solid-state supercapacitors capable of enduring 600%uniaxial tensile strain were developed with high specific capacitances of 1273 mF cm^(−2)(241 F g^(−1))and 514 mF cm^(−2)(95 F g^(−1)),***,their capacitances were well preserved after 1000 times of 600%stretch-release *** study showcased new possibilities of incorporating biobased lignin nanospheres in energy storage devices to fabricate stretchable devices leveraging synergies among various two-dimensional nanomaterials.

关键词： Hollow lignin nanospheres MXene Gradient-layered architecture Wrinkled electrodes Stretchable supercapacitors

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乳腺癌放射治疗的新动向:精、小、快

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中华乳腺病杂志（电子版） 2010年第2期4卷 6-7页

作者：余子豪中国医学科学院肿瘤医院放射治疗科北京100021

放射治疗在乳腺癌的综合治疗中有很重要的作用。近年来,乳腺癌放射治疗的发展动向可以简述为:精、小、快。[第一段]

关键词：乳腺肿瘤放射治疗

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乳腺癌放射治疗进展

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继续医学教育 2006年第8期20卷 53-56页

作者：余子豪中国医学科学院中国协和医科大学肿瘤医院北京100021

1早期乳腺癌的放射治疗 1.1乳腺癌的治疗以综合治疗为主,外科治疗有重要作用.乳腺癌外科治疗的第一个革新是由全乳切除术向保乳手术的演变.保乳治疗已成为Ⅰ、Ⅱ期乳腺癌的主要治疗方法.早期乳腺癌保乳治疗的原理是用手术切除原发灶,用... 详细信息

1早期乳腺癌的放射治疗 1.1乳腺癌的治疗以综合治疗为主,外科治疗有重要作用.乳腺癌外科治疗的第一个革新是由全乳切除术向保乳手术的演变.保乳治疗已成为Ⅰ、Ⅱ期乳腺癌的主要治疗方法.早期乳腺癌保乳治疗的原理是用手术切除原发灶,用中等剂量放疗控制亚临床病灶达到根治术的疗效,使病人保留完整的乳房,有良好的美容效果及功能。[第一段]

关键词：早期乳腺癌治疗进展放射治疗保乳治疗外科治疗全乳切除术 Ⅱ期乳腺癌亚临床病灶综合治疗保乳手术

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Primary early-stage intestinal and colonic non-Hodgkin's lymphoma: Clinical features, management, and outcome of 37 patients

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World Journal of Gastroenterology 2005年第37期11卷 5905-5909页

作者： Shu-Lian Wang Zhong-Xing Liao Xin-Fan Liu zi-hao yu Da-Zhong Gu Tu-Nan Qian Yong-Wen Song Jing Jin Wei-Hu Wang Ye-Xiong Li Department of Radiation Oncology Cancer HospitalPeking Union Medical College and Chinese Academy of Medical Sciences Beijing 100021 China Department of Radiation Oncology The University of Texas MD Anderson Cancer Center Houston 77030 TX USA

AIM： To analyze the clinical features, management, and outcome of treatment of patients with primary intestinal and colonic non-Hodgkin＇s lymphoma （PICL）. METHODS： A retrospective study was performed in 37 patients with early-stage PICL who were treated in our hospital from 1958 to 1998. Their clinical features, management, and outcome were assessed. Prognostic factors for survival were analyzed by univariate analysis using the Kaplan-Meier product-limit method and log-rank test. RESULTS： Twenty-five patients presented with Ann Arbor stage Ⅰ PICL and 12 with Ann Arbor stage Ⅱ PICL. Thirty-five patients underwent surgery （including 31 with complete resection）, 22 received postoperative chemotherapy or radiotherapy or both. Two patients with rectal tumors underwent biopsy and chemotherapy with or without radiotherapy. The 5- and 10-year overall survival （OS） rates were 51.9% and 44.5%. The corresponding diseasefree survival （DIS） rates were 42.4% and 37.7%. In univariate analysis, multiple-modality treatment was associated with a better DFS rate compared to single treatment （P= 0.001）. While age, tumor size, tumor site, stage, histology, or extent of surgery were not associated with OS and DFS, use of adjuvant chemotherapy significantly improved DFS （P = 0.031） for the 31 patients who underwent complete resection. Additional radiotherapy combined with chemotherapy led to a longer survival than chemotherapy alone in six patients with gross residual disease after surgery or ***： Combined surgery and chemotherapy is recommended for treatment of patients with PICL, Additional radiotherapy is needed to improve the outcome of patients who have gross residual disease after surgery.

关键词： Intestinal neoplasm Colonic neoplasm Non-Hodgkin's lymphoma Surgery Chemotherapy Radiotherapy

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Functional Verification for Agile Processor Development: A Case for Workflow Integration

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Journal of Computer Science & Technology 2023年第4期38卷 737-753页

作者：徐易难余子濠王凯帆王华强蔺嘉炜金越张林隽张紫飞唐丹王卅石侃孙凝晖包云岗 State Key Lab of Processors Institute of Computing TechnologyChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Beijing Institute of Open Source Chip Beijing 100080China

Agile hardware development methodology has been widely adopted over the past *** the research progress,the industry still doubts its applicability,especially for the functional verification of complicated processor *** verification commonly employs a simulation-based method of co-simulating the design under test with a reference model and checking the consistency of their outcomes given the same input *** observe limited collaboration and information exchange through the design and verification processes,dramatically leading to inefficiencies when applying the conventional functional verification workflow to agile *** this paper,we propose workflow integration with collaborative task delegation and dynamic information exchange as the design principles to effectively address the challenges on functional verification under the agile development *** on workflow integration,we enhance the functional verification workflows with a series of novel methodologies and *** diff-rule based agile verification methodology(DRAV)reduces the overhead of building reference models with runtime execution information from designs under *** present the RISC-V implementation for DRAV,DiffTest,which adopts information probes to extract internal design behaviors for co-simulation and *** further integrates two plugins,namely XFUZZ for effective test generation guided by design coverage metrics and LightSSS for efficient fault analysis triggered by co-simulation *** present the integrated workflows for agile hardware development and demonstrate their effectiveness in designing and verifying RISC-V processors with 33 functional bugs found in *** also illustrate the efficiency of the proposed toolchains with a case study on a functional bug in the L2 cache of XiangShan.

关键词： functional verification agile development open-source hardware workflow integration

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关于电气自动化技术在电气工程中的实践现状与发展探析

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今日自动化 2021年第12期 153-154页

作者：俞子豪南宁学院广西南宁530200

随着当前科学技术水平的提高,使得人们的生活也发生较大的改变。电气自动化技术被广泛的应用于实际生活中,更好的推动我国工业稳定向前发展。在电气工程中通过对电气自动化技术的应用,则是能够有效的解决传统工作中遇到的问题,在更好提... 详细信息

随着当前科学技术水平的提高,使得人们的生活也发生较大的改变。电气自动化技术被广泛的应用于实际生活中,更好的推动我国工业稳定向前发展。在电气工程中通过对电气自动化技术的应用,则是能够有效的解决传统工作中遇到的问题,在更好提高工作效率的同时,能确保设备自身的稳定。因此,文章了解电气自动化技术在电气工程中应用意义,分析电气自动化技术存在的问题,了解常见电气自动化技术,最后说明电气自动化技术在电气工程中应用体现,为相关研究人员提供参考。

关键词：电气自动化技术电气工程实践现状发展对策

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广东番茄曲叶病毒G2分离物基因组DNA-A的分子特征

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微生物学报 2005年第1期45卷 48-52页

作者：何自福虞皓罗方芳广东省农业科学院植物保护研究所

从采集于广东的番茄曲叶病病株上分离到病毒分离物G2 ,序列分析结果表明 ,其DNA_A为单链环状 ,全长2 74 4nt,共有 6个ORF ,其中病毒链上编码AV1(CP)、AV2 ,互补链上编码AC1、AC2、AC3和AC4。BLAST结果显示 ,与G2基因组有同源关系的病毒... 详细信息

从采集于广东的番茄曲叶病病株上分离到病毒分离物G2 ,序列分析结果表明 ,其DNA_A为单链环状 ,全长2 74 4nt,共有 6个ORF ,其中病毒链上编码AV1(CP)、AV2 ,互补链上编码AC1、AC2、AC3和AC4。BLAST结果显示 ,与G2基因组有同源关系的病毒均属双生病毒科菜豆金色花叶病毒属。序列比较结果显示 ,G2与菜豆金色花叶病毒属病毒的DNA_A序列同源率均不超过 83% ,其中同源率最高的是PaLCuCNV_[G10 ](82 8% )。进一步比较发现 ,它们的基因间隔区 (IR)变异最大 (同源率为 30 9%～ 81 8% ) ;CP氨基酸序列的同源率较高 (77 6 %～ 99 2 % ) ,AC4蛋白氨基酸序列的同源率较低 (4 3 5 %～ 78 8% )。系统进化关系分析结果也显示 ,G2与已报道的菜豆金色花叶病毒属病毒的亲缘关系均较远。因此 ,G2可能是双生病毒科菜豆金色花叶病毒属中一个未报道的新种 ,命名为广东番茄曲叶病毒 (TomatoleafcurlGuangdongVirus ,ToLCGDV)

关键词：广东番茄曲叶病毒 DNA-A 序列分析分子特征

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Phase Ⅰ study of postoperative radiotherapy combined with capecitabine for gastric cancer

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World Journal of Gastroenterology 2014年第4期20卷 1067-1073页

作者： Xin Wang Jing Jin Ye-Xiong Li Hua Ren Hui Fang Shu-Lian Wang yue-Ping Liu Wei-Hu Wang zi-hao yu Yong-Wen Song Xin-Fan Liu Department of Radiation Oncology Cancer Hospital National Cancer Center Chinese Academy of Medical Sciences and Peking Union Medical College

AIM: To determine the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of capecitabine combined with postoperative radiotherapy for gastric cancer.

关键词： Radiotherapy Capecitabine Gastric cancer Maximum tolerated dose Dose-limiting toxicity

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