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Hybrid treatment of varied orthodontic appliances for a patient with skeletal class II and temporomandibular joint disorders:A case report and review of literature

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World Journal of Clinical Cases 2024年第2期12卷 431-442页

作者： Tong Lu Li Mei Bao-Chao Li zi-Wei huang huang Li Department of Orthodontics Nanjing Stomatological HospitalThe Affiliated Hospital of Medical SchoolNanjing UniversityNanjing 210008Jiangsu ProvinceChina Discipline of Orthodontics Department of Oral ScienceFaculty of DentistryUniversity of OtagoDunedin 9016New Zealand

BACKGROUND The relation between orthodontic treatment and temporomandibular disorders(TMDs)is under debate;the management of TMD during orthodontic treatment has always been a *** TMD symptoms occur during orthodontic treatment,an immediate pause of orthodontic adjustments is recommended;the treatment can resume when the symptoms are managed and *** SUMMARY This case report presents a patient(26-year-old,female)with angle class I,skeletal class II and *** treatment was a hybrid of clear aligners,fixed appliances and temporary anchorage devices(TADs).After 3 mo resting and treatment on her TMD,the patient’s TMD symptom alleviated,but her anterior occlusion displayed deep ***,the fixed appliances with TAD were used to correct the anterior deep-bite and level maxillary and mandibular deep *** the levelling,the patient showed dual bite with centric relation and maximum intercuspation discrepancy on her *** careful examination of temporomandibular joints(TMJ)position,the stable bite splint and Invisible Mandibular Advancement appliance were used to reconstruct her ***,the improved facial appearance and relatively stable occlusion were *** 1-year follow-up records showed there was no obvious change in TMJ morphology,and her occlusion was *** TMD screening and monitoring is of great clinical importance in the TMD susceptible *** treatment with clear aligners and fixed appliances and TADs is an effective treatment modality for the complex cases.

关键词： Temporomandibular disorder Skeletal class II Deep overbite Dual bite Invisible mandibular advancement appliance Case report

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Carbon uptake by cement in China:Estimation and contribution to carbon neutrality goals

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Science China Earth Sciences 2024年第6期67卷 2056-2067页

作者： Mingjing MA zi huang Jiaoyue WANG Le NIU Wenfeng ZHANG Xiaowei XU Fengming XI Zhu LIU Institute of Applied Ecology Chinese Academy of SciencesShenyang 110016China College of Resources and Environment University of Chinese Academy of SciencesBeijing 100049China Department of Earth System Science Tsinghua UniversityBeijing 100084China Department of Engineering Science University of OxfordOxfordOX13UK

Cement is a widely used construction material *** manufacturing contributes to anthropogenic CO_(2)emissions ***,its alkaline compounds can absorb CO_(2)from the surrounding environment and engage in a carbonation reaction,thereby functioning as a carbon *** a major cement producer and consumer,China has an important responsibility to rigorously investigate and accurately account for cement carbon *** study presents a comprehensive analytical model of cement carbon uptake from China,revealing a substantial increase in carbon uptake from 1930 to 2021,peaking at 426.77 Mt CO_(2)(95% Confidence Interval:317.67-874.33 Mt CO_(2))in *** uptake accounts for 8.10% to 45.40% of China’s annual land sink and 2.51% to 4.54% of the global land *** cumulative carbon uptake by cement is approximately 7.06 Gt CO_(2)(95%CI:5.22–9.44 Gt CO_(2))during this period,offsetting 50.7% of the total emissions(13.91 Gt CO_(2),95%CI:12.44–17.00 Gt CO_(2))from the cement ***,cement mortar contributed to most absorption(65.64%).From a life cycle perspective,the service stage of cement materials is the period where the largest CO_(2)sink is formed,accounting for 90.03% of the ***,the potential for carbon sequestration in cement materials and their waste is ***,the model improves the accuracy of cement carbon accounting,supporting both China and global carbon neutrality ***,it is crucial for China to achieve its carbon neutrality goals sooner by prioritizing the environmental benefits of cement materials and wastes,and accelerating the development and commercialization of CO_(2)sequestration technologies for cement and its by-products.

关键词： Cement Carbon uptake Life cycle assessment Carbon emission reduction Carbon neutrality

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Self organizing optimization and phase transition in reinforcement learning minority game system

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Frontiers of physics 2024年第4期19卷 297-309页

作者： Si-Ping Zhang Jia-Qi Dong Hui-Yu Zhang Yi-Xuan Lü Jue Wang zi-Gang huang Key Laboratory of Biomedical Information Engineering of Ministry of Education Key Laboratory of Neuro-informatics&Rehabilitation Engineering of Ministry of Civil Affairsand Institute of Health and Rehabilitation ScienceSchool of Life Science and TechnologyXi’an Jiaotong UniversityXi’an 710049China Lanzhou Center for Theoretical Physics and Key Laboratory of Theoretical Physics of Gansu Province Lanzhou UniversityLanzhou 730000China

Whether the complex game system composed of a large number of artificial intelligence(AI)agents empowered with reinforcement learning can produce extremely favorable collective behaviors just through the way of agent self-exploration is a matter of practical *** this paper,we address this question by combining the typical theoretical model of resource allocation system,the minority game model,with reinforcement *** individual participating in the game is set to have a certain degree of intelligence based on reinforcement learning *** particular,we demonstrate that as AI agents gradually becomes familiar with the unknown environment and tries to provide optimal actions to maximize payoff,the whole system continues to approach the optimal state under certain parameter combinations,herding is effectively suppressed by an oscillating collective behavior which is a self-organizing pattern without any external *** interesting phenomenon is that a first-order phase transition is revealed based on some numerical results in our multi-agents system with reinforcement *** order to further understand the dynamic behavior of agent learning,we define and analyze the conversion path of belief mode,and find that the self-organizing condensation of belief modes appeared for the given trial and error rates in the AI ***,we provide a detection method for period-two oscillation collective pattern emergence based on the Kullback–Leibler divergence and give the parameter position where the period-two appears.

关键词： oscillatory evolution collective behaviors phase transition reinforcement learning minority game

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A Dear Price to Regret Over:On ***’Dignity and Professionalism in The Remains of the Day

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Journal of Literature and Art Studies 2024年第6期14卷 415-419页

作者： huang zi-jie University of Shanghai for Science and Technology ShanghaiChina

The Remains of the Day is one of Kazuo Ishiguro’s renowned *** protagonist Stevens is an English butler whose life is deeply entwined with the concepts of dignity and *** against the backdrop of post-World War II Britain and reflecting on the interwar period,the novel examines Stevens’devotion to his role and the traditional values of English *** essay discusses how Stevens’identity is shaped by his unwavering commitment to professionalism and his admiration for British gentleman culture and highlights the identity crisis Stevens faces as he realizes the flawed nature of his employer and the outdated ideals he *** Stevens’journey of self-reassessment and eventual epiphany,the essay delves into the complexities of his internal struggle to reconstruct his identity,ultimately advocating for a more authentic understanding of dignity and honor.

关键词： The Remains of the Day dignity and honor identity professionalism

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Evolution of helium bubbles in FeCoNiCr-based high-entropy alloys containing γ′ nanoprecipitates

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Chinese Physics B 2024年第7期33卷 491-500页

作者：冯婷蒋胜明胡潇天张子骏黄子敬董士刚张建 College of Energy Xiamen UniversityXiamen 361005China16

A series of high-entropy alloys(HEAs) containing nanoprecipitates of varying sizes is successfully prepared by a non-consuming vacuum arc melting *** order to study the irradiation evolution of helium bubbles in the FeCoNiCrbased HE As with γ' precipitates,these samples are irradiated by 100-keV helium ions with a fluence of 5 × 10^(20) ions/m^(2) at 293 K and 673 K,*** the samples irradiated at room temperature are annealed at different temperatures to examine the diffusion behavior of helium *** electron microscope(TEM) is employed to characterize the structural morphology of precipitated nanoparticles and the evolution of helium *** results reveal that nanosized,spherical,dispersed,coherent,and ordered L1_(2)-type Ni_(3)Ti γ' precipitations are introduced into FeCoNiCr(Ni_(3)Ti)_(0.1) HEAs by means of ageing treatments at temperatures between 1073 K and 1123 *** the ageing treatment conditions adopted in this work,γ' nanoparticles are precipitated in FeCoNiCr(Ni_(3)Ti)_(0.1) HE As,with average diameters of 15.80 nm,37.09 nm,and 62.50 nm,*** average sizes of helium bubbles observed in samples after 673-K irradiation are 1.46 nm,1.65 nm,and 1.58 nm,*** improvement in the irradiation resistance of FeCoNiCr(Ni_(3)Ti)_(0.1) HEAs is evidenced by the diminution in bubbles ***,the FeCoNiCr(Ni_(3)Ti)_(0.1) HEAs containing γ' precipitates of 15.8 nm exhibits the minimum size and density of helium bubbles,which can be ascribed to the considerable helium trapping effects of heterogeneous coherent phase ***,annealing experiments conducted after 293-K irradiation indicate that HEAs containing precipitated phases exhibits smaller apparent activation energy(E_(a)) for helium bubbles,resulting in larger helium bubble *** study provides guidance for improving the irradiation resistance of L1_(2)-strengthened high-entropy alloy.

关键词： high-entropy alloys irradiation resistance coherent precipitates helium bubbles

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Hepatic arterial infusion chemotherapy with anti-angiogenesis agents and immune checkpoint inhibitors for unresectable hepatocellular carcinoma and meta-analysis

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World Journal of Gastroenterology 2024年第4期30卷 318-331页

作者： Yu-Zhe Cao Guang-Lei Zheng Tian-Qi Zhang Hong-Yan Shao Jia-Yu Pan zi-Lin huang Meng-Xuan Zuo Department of Minimally Invasive Interventional Therapy Sun Yat-sen University Cancer CenterGuangzhou 510060Guangdong ProvinceChina Department of Minimally Invasive Interventional Therapy State Key Laboratory of Oncology in South ChinaGuangzhou 510060Guangdong ProvinceChina Department of Minimally Invasive Interventional Therapy Guangdong Provincial Clinical Research Center for CancerGuangzhou 510060Guangdong ProvinceChina

BACKGROUND Hepatic arterial infusion chemotherapy(HAIC)has been proven to be an ideal choice for treating unresectable hepatocellular carcinoma(uHCC).HAIC-based treatment showed great potential for treating ***,large-scale studies on HAIC-based treatments and meta-analyses of first-line treatments for uHCC are *** To investigate better first-line treatment options for uHCC and to assess the safety and efficacy of HAIC combined with angiogenesis inhibitors,programmed cell death of protein 1(PD-1)and its ligand(PD-L1)blockers(triple therapy)under real-world *** Several electronic databases were searched to identify eligible randomized controlled trials for this ***-level pooled analyses of hazard ratios(HRs)and odds ratios(ORs)were *** was a retrospective single-center study involving 442 patients with uHCC who received triple therapy or angiogenesis inhibitors plus PD-1/PD-L1 blockades(AIPB)at Sun Yat-sen University Cancer Center from January 2018 to April *** score matching(PSM)was performed to balance the bias between the *** Kaplan-Meier method and cox regression were used to analyse the survival data,and the log-rank test was used to compare the suvival time between the *** A total of 13 randomized controlled trials were *** alone and in combination with sorafenib were found to be effective treatments(P values for ORs:HAIC,0.95;for HRs:HAIC+sorafenib,0.04).After PSM,176 HCC patients were included in the *** triple therapy group(n=88)had a longer median overall survival than the AIPB group(n=88)(31.6 months vs 14.6 months,P<0.001)and a greater incidence of adverse events(94.3%vs 75.4%,P<0.001).CONCLUSION This meta-analysis suggests that HAIC-based treatments are likely to be the best choice for *** findings confirm that triple therapy is more effective for uHCC patients than AIPB.

关键词： Unresectable hepatocellular carcinoma Hepatic arterial infusion chemotherapy Angiogenesis inhibitors Programmed cell death protein 1 Programmed death ligand 1

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Different concentrations of hyaluronic acid eye drops for dry eye syndrome: a systematic review and Meta-analysis

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International Journal of Ophthalmology(English edition) 2024年第6期17卷 1110-1119页

作者： Xiao-Wei Ouyang Sheng Fang Yun-Min Yi Shi-Peng Zou Qi-Yu Hu zi-Xuan huang Qing-Xia Li Jin-Yan Luo Department of Ophthalmology Nanchang Hongdu Hospital of Traditional Chinese MedicineNanchang 330000Jiangxi ProvinceChina Department of Ophthalmology Jiangxi Hospital of Integrated Traditional Chinese and Western MedicineNanchang 330000Jiangxi ProvinceChina Department of Cataract Nanchang University Affiliated Eye HospitalNanchang 330000Jiangxi ProvinceChina Department of Neuro-ophthalmology Nanchang University Affiliated Eye HospitalNanchang 330000Jiangxi ProvinceChina

AIM:To compare high or low concentration of hyaluronic acid eye drops(HY)for dry eye syndromes(DES).METHODS:Randomized controlled trials(RCTs)comparing various concentrations of HY were searched in PubMed,Embase,Web of Science,Cochrane,SinoMed,CNKI,Wanfang Database,CQVIP,and Chinese journals databases between inception and July *** standardized mean differences(SMD)or weighted mean difference(WMD)with 95%confidence intervals(CI)from RCTs evaluating Schirmer’s I test(SIT),corneal fluorescein staining score(CFS),tear breakup time(TBUT),DES score(DESS),and Ocular Surface Disease Index(OSDI)were *** analysis,Egger’s test and Meta-regression analysis were performed for all ***:We conducted a Meta-analysis of 10 RCTs that met the inclusion criteria,involving 1796 ***-concentrations group significantly improved the outcome of CFS according to random effects modelling(SMD,-3.37;95%CI,-5.25 to-1.48;P=0.0005).The rest of the results were not statistically significant,including indicators such as SIT,TBUT,DESS and ***:For dry eyes with positive corneal staining,a high concentration of HY is recommended,whereas in other cases,a high concentration of HY does not offer a more pronounced advantage over a low concentration of HY in the treatment of dry eyes.

关键词： dry eye hyaluronic acid concentration Meta-analysis

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All-sky Guide Star Catalog for CSST

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Research in Astronomy and Astrophysics 2024年第4期24卷 35-59页

作者： Hui-Mei Feng zi-huang Cao Man I Lam Ran Li Hao Tian Da-Yi Yin Yuan-Yu Yang Xin Zhang Dong-Wei Fan Yi-Qiao Dong Xin-Feng Li Wei Wang Long Li Hugh RAJones Yi-Han Tao Jia-Lu Nie Pei-Pei Wang Mao-Yuan Liu He-jun Yang Chao Liu Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000China Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China University of ChineseAcademy of Sciences Beijing 100049China Shanghai Institute of Technical Physics Chinese Academy of SciencesShanghai200083China Technology and Engineering Center for Space Utilization.Chinese Academy of Sciences Beijing 100094China Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China Centre for Astrophysics University of HertfordshireHatfieldUK Beijing University of Technology Beijing 100124China

The China Space Station Telescope(CSST)is a two-meter space telescope with multiple back-end *** Fine Guidance Sensor(FGS)is an essential subsystem of the CSST Precision Image Stability System to ensure the required absolute pointing accuracy and line-of-sight *** this study,we construct the Main Guide Star Catalog for *** accomplish this,we utilize the information about the FGS and object information from the Gaia Data Release *** provide an FGS instrument magnitude and exclude variables,binaries,and high proper motion stars from the catalog to ensure uniform FGS guidance ***,we generate a HEALPix index,which provides a hierarchical tessellation of the celestial sphere,and employ the Voronoi algorithm to achieve a homogeneous distribution of stars across the *** distribution ensures adequate coverage and sampling of the *** performance of the CSST guide star catalog was assessed by simulating the field of view of the FGS according to the CSST mock survey strategy *** analysis of the results indicates that this catalog provides adequate coverage and *** catalog's performance meets the FGS requirements,ensuring the functioning of the FGS and its guidance capabilities.

关键词： catalogs astrometry instrumentation:detectors

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白花蛇舌草提取物对肝癌术后感染大鼠PI3K/AKT/mTOR信号通路的调控作用

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中华医院感染学杂志 2024年第5期34卷 733-737页

作者：张子强罗刚黄子锋林一煌江帆武汉科技大学附属普仁医院肝胆胰外科湖北武汉430081 武汉科技大学医学院湖北武汉430065

目的分析白花蛇舌草提取物对肝癌术后感染大鼠磷脂酰肌醇3激酶(PI3K)/蛋白激酶B(AKT)/哺乳动物雷帕霉素靶蛋白(m TOR)信号通路的调控作用。方法选取SPF级Wistar大鼠44只,10只为空白组,剩余34只建立肝癌术后感染模型,共有30只大鼠建模... 详细信息

目的分析白花蛇舌草提取物对肝癌术后感染大鼠磷脂酰肌醇3激酶(PI3K)/蛋白激酶B(AKT)/哺乳动物雷帕霉素靶蛋白(m TOR)信号通路的调控作用。方法选取SPF级Wistar大鼠44只,10只为空白组,剩余34只建立肝癌术后感染模型,共有30只大鼠建模成功,将其分为模型组、药物对照组、白花蛇舌草提取物组3组,每组10只。药物对照组给予阿莫西林克拉维酸钾,白花蛇舌草提取物组给予白花蛇舌草提取物,空白组、模型组不做处理,干预7d后观察大鼠变化。结果与空白组相比,模型组、药物对照组、白花蛇舌草提取物组外周血C-反应蛋白(CRP)、白细胞介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)、丙氨酸氨基转移酶(ALT)、总胆红素(TBil)、天冬氨酸氨基转移酶(AST)、总胆汁酸(TBA)水平、PI3K、AKT、mTOR mRNA表达量及相对表达量上升(P<0.05);与模型组相比,药物对照组、白花蛇舌草提取物组CRP、IL-8、TNF-α、ALT、TBil、AST、TBA水平、PI3K、AKT、mTOR mRNA表达量及相对表达量下降(P <0.05);与药物对照组相比,白花蛇舌草提取物组CRP、IL-8、TNF-α、ALT、TBil、AST、TBA水平、PI3K、AKT、mTOR mRNA表达量及相对表达量下降(P <0.05)。结论肝癌术后感染大鼠经白花蛇舌草提取物干预后炎症反应减轻,肝损伤缓解,其机制可能与PI3K/AKT/mTOR信号通路受抑有关。

关键词：肝癌感染白花蛇舌草提取物磷脂酰肌醇3激酶/蛋白激酶B/哺乳动物雷帕霉素靶蛋白

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汉隋之间四厢乐制因革考

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艺术学研究 2024年第3期 116-126页

作者：黄紫中山大学中文系

四厢乐制的建立与发展是对礼乐文化建设和政治制度变迁的重要反映,其内涵范畴的增减受到政权迭代、物质条件变化等多方面因素的影响。四厢乐制以汉代东厢雅乐为基础,在魏晋扩展为四厢,南北朝时期虽遭遇大动荡,但它依然保持着一定的坚韧... 详细信息

四厢乐制的建立与发展是对礼乐文化建设和政治制度变迁的重要反映,其内涵范畴的增减受到政权迭代、物质条件变化等多方面因素的影响。四厢乐制以汉代东厢雅乐为基础,在魏晋扩展为四厢,南北朝时期虽遭遇大动荡,但它依然保持着一定的坚韧性与连贯性,最终在南朝梁武帝的努力下重现光辉,并在隋统一后成为新政权礼乐建设的重要参考。四厢乐制一方面见证了东汉知识整合浪潮对汉魏六朝思想和制度实践的影响,另一方面也为隋、唐雅乐建设提供了相对成熟的制度范式。

关键词：东厢雅乐四厢乐制礼乐乐律月令笛律

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