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Journal of Meteorological Research 2024年第3期38卷 542-557页

作者： Rui WANG Yihong DUAN Jianing feng Department of Atmospheric and Oceanic Sciences&Institute of Atmospheric Sciences Fudan UniversityShanghai200438China State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesChina Meteorological AdministrationBeijing100081China

Cloud microphysics plays an important role in determining the intensity and precipitation of tropical cyclones(TCs).In this study,a high-resolution numerical simulation by WRF(version 4.2)of Typhoon Meranti(2016)during its rapid intensification(RI)period was conducted and validated by multi-source observations including Cloud-Sat and Global Precipitation Mission satellite *** snow and ice particles content were found to increase most rapidly compared with other hydrometeors during the RI *** all hydrometeors continued to *** graupel content only increased in the initial RI stage,and then decreased afterwards due to precipitation during the RI *** addition,sea surface temperature(SST)sensitivity experiments showed that,although the intensity of the TC increased with a higher SST,not all hydrometeors *** graupel content continued to increase with the increase in SST,mainly due to the accumulation of more lower-temperature supercooled water vapor at the corresponding *** content of snow decreased with the increase in SST because stronger vertical motion at the corresponding height affected the aggregation of ice crystals.

关键词： tropical cyclone rapid intensification cloud microphysical characteristics sea surface temperature(SST)

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Liquid-mediated Ostwald ripening of Ag-based clusters supported on oxides

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Nano Research 2024年第6期17卷 4971-4978页

作者： Conghui Liu Rongtan Li Yamei Fan Shiwen Li Xiaohui feng Lu feng Yanxiao Ning Qiang Fu School of Chemistry Dalian University of TechnologyDalian 116024China State Key Laboratory of Catalysis Chinese Academy of SciencesDalian Institute of Chemical PhysicsDalian 116023China

Reconstruction of supported nanocatalysts often occurs in gas-solid reactions and significantly affects the catalytic performance,yet it is much less explored in liquid-phase ***,we find that highly-dispersed Ag nanocatalysts,i.e.,AgOx clusters,supported on alumina,silica,and titania,can aggregate into larger Ag or Ag2O particles after immersing in liquid-phase media at room *** spontaneous aggregation of AgOx clusters in liquid water is attributed to liquid-phase Ostwald ripening through dissolution of AgOx clusters into water and subsequent redeposition to form Ag2O *** immersion into organic solvents such as ethanol leads to reduction of AgOx clusters and further growth into Ag *** work reveals that liquid-phase reaction media can induce substantial structural evolution of supported nanostructured catalysts,which should be carefully considered in liquid-solid interface catalytic reactions such as electrocatalysis,environmental catalysis,and organic synthesis in liquid phase.

关键词： Ag catalysts Ostwald ripening liquid phase media dissolution-deposition process

Development of high-power microwave mechanical integrated continuous mining device

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第9期16卷 3365-3377页

作者： Xia-Ting feng feng Lin Jiuyu Zhang Chengxiang Yang Yuntan Ao Tianyang Tong Key Laboratory of Ministry of Education on Safe Mining of Deep Metal Mines Northeastern UniversityShenyang110819China Key Laboratory of Liaoning Province on Deep Engineering and Intelligent Technology Northeastern UniversityShenyang110819China

This article introduces a high-power microwave mechanical integrated continuous mining device,which can achieve synchronous cutting of hard rocks by microwave and *** device includes a cutting system,a rotary translation system,a loading system,a high-power microwave system,and a control and monitoring *** technology of“master-slave follow-up”disc cutter alternating side cutting of rock was proposed,which could improve the effectiveness of rock *** integrated structure of a microwave-cut system was then proposed,and synchronous motion of the microwave-cut system and adjustment of the loading system could be *** automatic adjustment technology of the microwave working distance was developed to dynamically control the optimal microwave working *** basic functions of the equipment were verified by *** comparing the two types of disk cutters,it is found that the master-slave follow-up disk cutter can improve significantly the dust removal effect and rock breaking efficiency in rock breaking process versus the conventional large disc *** tests of slate with or without microwave were conducted using a master-slave follow-up disk *** results show that the cutting patterns of slates change from intermittent chunks(without microwave irradiation)to persistent debris(with microwave irradiation),and the cutting speed is significantly improved(170%).The development of the device provides a scientific basis for changing the conventional mining technology of metal mines and realizing the mechanical continuous mining in hard metal mines.

关键词： Hard metal mine Microwave machinery Continuous mining Master-slave follow-up disc cutter

Higher-order expansions of powered extremes of logarithmic general error distribution

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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 47-54页

作者： TAN Xiao-feng LI Li-hui School of Mathematics and Statistics Southwest UniversityChongqing 400715China

In this paper,Let M_(n)denote the maximum of logarithmic general error distribution with parameter v≥***-order expansions for distributions of powered extremes M_(n)^(p)are derived under an optimal choice of normalizing *** is shown that M_(n)^(p),when v=1,converges to the Frechet extreme value distribution at the rate of 1/n,and if v>1 then M_(n)^(p)converges to the Gumbel extreme value distribution at the rate of(loglogn)^(2)=(log n)^(1-1/v).

关键词： logarithmic general error distribution convergence rate higher-order expansion powered ex-treme

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Upcycling electroplating sludge into bioengineering-enabled highly stable dual-site Fe-Ni_(2)P@C electrocatalysts for efficient oxygen evolution

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Nano Research 2024年第8期17卷 6984-6992页

作者： Jiawen Liu Zunpeng Zuo feng Gao Kai Yi Jiahui Lin Mengye Wang Zhang Lin feng Huang State Key Laboratory of Optoelectronic Materials and Technologies School of MaterialsSun Yat-Sen UniversityGuangzhou 510275China Department of Chemistry City University of Hong KongHong Kong 999077China School of Metallurgy and Environment Central South UniversityChangsha 410083China Ganjiang Innovation Academy Chinese Academy of SciencesGanzhou 341000China

The advancement of bimetallic catalysts holds significant promise for the innovation of oxygen evolution reaction(OER)*** from adsorbate evolution mechanism(AEM)and lattice oxygen oxidation mechanism(LOM),the incorporation of dual active sites has the potential to foster novel OER pathways,such as the coupled oxygen evolution mechanism(COM),which can surpass the limitations of OER and elevate catalytic *** this study,uniformly distributed Fe/Ni dual-site Fe-Ni_(2)P@C electrocatalysts are crafted by upcycling metals in electroplating sludge via an eco-friendly and sustainable microbial engineering *** findings indicate that a substantial number of defects emerge at the Ni2P crystal during the OER process,laying the groundwork for lattice oxygen ***,the displacement of Ni/Fe in the crystal lattice intensifies the asymmetry of the electronic structure at the metal active sites,facilitating the deprotonation *** research introduces an innovative paradigm for the synthesis of effective and robust transition metal-based OER catalysts,with implications for sustainable energy generation technologies.

关键词： oxygen evolution reaction dual active sites adsorbate evolution mechanism lattice oxygen mechanism bioengineering

Cotton leaf disease detection method based on improved SSD

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International Journal of Agricultural and Biological Engineering 2024年第2期17卷 211-220页

作者： Wenjuan Guo Shuo feng Quan feng Xiangzhou Li Xueze Gao College of Mechanical and Electrical Engineering Gansu Agricultural UniversityLanzhou 730070China School of Cyber Security Gansu University of Political Science and LawLanzhou 730070China College of Mechanical and Electrical Engineering Sichuan Agricultural UniversityYa’an 625014China

In response to the problems of numerous model parameters and low detection accuracy in SSD-based cotton leaf disease detection methods,a cotton leaf disease detection method based on improved SSD was proposed by combining the characteristics of cotton leaf ***,the lightweight network MobileNetV2 was introduced to improve the backbone feature extraction network,which provides more abundant semantic information and details while significantly reducing the amount of model parameters and computing complexity,and accelerates the detection speed to achieve real-time ***,the SE attention mechanism,ECA attention mechanism,and CBAM attention mechanism were fused to filter out disease target features and effectively suppress the feature information of jamming targets,generating feature maps with strong semantics and precise location *** test results on the self-built cotton leaf disease dataset show that the parameter quantity of the SSD_MobileNetV2 model with backbone network of MobileNetV2 was 50.9%of the SSD_VGG model taking VGG as the *** with SSD_VGG model,the P,R,F1 values,and mAP of the MobileNetV2 model increased by 4.37%,3.3%,3.8%,and 8.79%respectively,while FPS increased by 22.5 frames/*** SE,ECA,and CBAM attention mechanisms were introduced into the SSD_VGG model and SSD_MobileNetV2 *** gradient weighted class activation mapping algorithm to explain the model detection process and visually compare the detection results of each *** results indicate that the P,R,F1 values,mAP and FPS of the SSD_MobileNetV2+ECA model were higher than other models that introduced the attention ***,this model has less parameter with faster running speed,and is more suitable for detecting cotton diseases in complex environments,showing the best detection ***,the improved SSD_MobileNetV2+ECA model significantly enhanced the semantic information of the shallow feature map of the model,and has a goo

关键词： cotton disease detection SSD MobileNetV2 attention mechanism

Network Pharmacology Based Elucidation of Molecular Mechanisms of Laoke Formula for Treatment of Advanced Non-Small Cell Lung Cancer

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Chinese Journal of Integrative Medicine 2024年第11期30卷 984-992页

作者： feng Yu-yu LIU Jin-feng XUE Yang LIU Dan WU Xiong-zhi Department of Nursing Tangshan Vocational and Technical College School of Chinese Materia Medica Tianjin University of Traditional Chinese Medicine Department of Oncology Tianjin Medical University General Hospital Tianjin Medical University Cancer Institute and Hospital National Clinical Research Center for Cancer Key Laboratory of Cancer Prevention and Therapy Tianjin's Clinical Research Center for China Tianjin Nankai Hospital Tianjin Medical University

Objective: To explore the specific pharmacological molecular mechanisms of Laoke Formula(LK)on treating advanced non-small cell lung cancer(NSCLC) based on clinical application, network pharmacology and experimental validation. Methods: Kaplan-Meier method and Cox regression analysis were used to evaluate the survival benefit of Chinese medicine(CM) treatment in 296 patients with NSCLC in Tianjin Medical University Cancer Institute and Hospital from January 2011 to December 2015. The compounds of LK were screened using the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform, and the corresponding targets were performed from Swiss Target Prediction. NSCLC-related targets were obtained from Therapeutic Target Database and Comparative Toxicogenomics Database. Key compounds and targets were identified from the compound-target-disease network and protein-protein interaction(PPI) network analysis, respectively. Kyoto Encyclopedia of Genes and Genomes(KEGG) and Gene Ontology(GO) enrichment analysis were used to predict the potential signaling pathways involved in the treatment of advanced NSCLC with LK. The binding affinities between key ingredients and targets were further verified using molecular docking. Finally, A549 cell proliferation and migration assay were used to evaluate the antitumor activity of LK. Western blot was used to further verify the expression of key target proteins related to the predicted pathways. Results: Kaplan-Meier survival analysis showed that the overall survival of the CM group was longer than that of the non-CM group(36 months vs.26 months), and COX regression analysis showed that LK treatment was an independent favorable prognostic factor(P=0.027). Next, 97 components and 86 potential targets were included in the network pharmacology, KEGG and GO analyses, and the results indicated that LK was associated with proliferation and apoptosis. Moreover,molecular docking revealed a good binding affinity between the key

关键词： Chinese medicine LaoKe Formula anti-tumor network pharmacology non-small cell lung cancer

Covariate-Assisted Matrix Completion with Multiple Structural Breaks

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Journal of Systems Science & Complexity 2024年第2期37卷 692-728页

作者： MENG Jing feng Long ZOU Changliang WANG Zhaojun School of Statistics and Data Science KLMDASRLEBPSand LPMCNankai UniversityTianjin 300071China

In matrix completion,additional covariates often provide valuable information for completing the unobserved entries of a high-dimensional low-rank matrix *** this paper,the authors consider the matrix recovery problem when there are multiple structural breaks in the coefficient matrix β under the column-space-decomposition model A=Xβ+B.A cumulative sum(CUSUM)statistic is constructed based on the penalized estimation of β.Then the CUSUM is incorporated into the Wild Binary Segmentation(WBS)algorithm to consistently estimate the location of ***,a nearly-optimal recovery of A is *** findings are further corroborated via numerical experiments and a real-data application.

关键词： Additional covariates matrix completion multiple structural breaks wild Binary Segmentation

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Galectin 2 regulates JAK/STAT3 signaling activity to modulate oral squamous cell carcinoma proliferation and migration in vitro

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BIOCELL 2024年第5期48卷 793-801页

作者： XINRU feng LI XIAO Medical School University of Electronic Science and Technology of ChinaChengdu610072China Department of Stomatology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu610072China

Background:Galectin 2(LGALS2)is a protein previously reported to serve as a mediator of disease progression in a range of *** function of LGALS2 in oral squamous cell carcinoma(OSCC),however,has yet to be explored,prompting the present study to address this literature ***:Overall,144 paired malignant tumor tissues and paracancerous OSCC patient samples were harvested and the LGALS2 expression levels were examined through qPCR and western *** LGALS2 coding sequence was introduced into the pcDNA3.0 vector,to enable the overexpression of this gene,while an LGALS2-specific shRNA and corresponding controls were also *** functionality of LGALS2 as a regulator of the ability of OSCC cells to grow and undergo apoptotic death in vitro was assessed through EdU uptake and CCK-8 assays,and flow cytometer,whereas a Transwell system was used to assess migratory activity and *** agonist of the Janus Kinase 2(JAK2)/Signal Transducer and Activator of Transcription 3(STAT3)pathway was also used to assess the role of this pathway in the context of LGALS2 ***:Here,we found that lower LGALS2 protein and mRNA expression were evident in OSCC tumor tissue samples,and these expression levels were associated with clinicopathological characteristics and patient survival *** LGALS2 enhanced proliferation in OSCC cells while rendering these cells better able to resist *** opposite was instead observed after LGALS2 was ***,the ability of LGALS2 to suppress the progression of OSCC was related to its ability to activate the JAK/STAT3 signaling ***:Those results suggest a role for LGALS2 as a suppressor of OSCC progression through its ability to modulate JAK/STAT3 signaling,supporting the potential utility of LGALS2 as a target for efforts aimed at treating OSCC patients.

关键词： LGALS2 Oral squamous cell carcinoma(OSCC) Janus Kinase 2/Signal Transducer and Activator of Transcription 3(JAK2-STAT3) Progression

Monocyte to High-density Lipoprotein Cholesterol Ratio as a Predictor of Nonalcoholic Fatty Liver Disease in Childhood Obesity

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Current Medical Science 2024年第4期44卷 692-697页

作者： Jun-feng ZHANG feng-qing CAI Xiu-cai ZHANG Qing YE Department of Laboratory Medicine Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhou310052China

Objective Inflammation is involved in the development and progression of nonalcoholic fatty liver disease(NAFLD).The monocyte to high-density lipoprotein cholesterol ratio(MHR)has emerged as a marker for various inflammation-related *** aim of the present study was to investigate the association between the MHR and NAFLD in a population with childhood *** Based on hepatic ultrasound,a total of 504 children with obesity(357 with NAFLD and 147 without NAFLD)were included in the *** correlation between the MHR and NAFLD risk factors was assessed by Pearson’s and Spearman’s *** stepwise logistic regression analyses were conducted to explore the association between the MHR and the risk of *** The MHR in patients with NAFLD was significantly greater than that in patients without NAFLD[0.52(0.44-0.67)versus 0.44(0.34-0.57),P<0.001].Multivariate stepwise logistic regression analysis demonstrated that the MHR[odds ratio(OR):1.033,95%confidence interval(CI):1.015-1.051;P<0.001]was an independent predictor of NAFLD in childhood obesity patients,as were age(OR:1.205,95%CI:1.059-1.371;P=0.005],waist circumference[OR:1.037,95%CI:1.008-1.067;P=0.012],and alanine transaminase[OR:1.067,95%CI:1.045-1.089;P<0.001].Additionally,MHR quartiles showed a significant positive association with the incidence of NAFLD after adjusting for potential confounding *** The present study showed that the MHR may serve as an available and useful indicator of NAFLD in individuals with childhood obesity.

关键词： nonalcoholic fatty liver disease obesity monocyte-to-high-density lipoprotein ratio marker