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Spatiotemporal heterogeneity of schistosomiasis in China's Mainland:Evidence from a multi-stage continuous downscaling sentinel monitoring

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Asian Pacific Journal of Tropical Medicine 2022年第1期15卷 26-34页

作者： Yanfeng Gong Jiaxin Feng zhuowei luo Jingbo Xue Zhaoyu Guo Lijuan Zhang Shang Xia Shan Lv Jing Xu Shizhu Li National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionShanghai 200025China Chinese Center for Tropical Diseases Research Shanghai 200025China NHC Key Laboratory of Parasite and Vector Biology Shanghai 200025China WHO Collaborating Centre for Tropical Diseases Shanghai 200025China National Center for International Research on Tropical Diseases Shanghai 200025China School of Global Health Chinese Center for Tropical Diseases ResearchShanghai Jiao Tong University School of MedicineShanghai 200025China

Objective:To determine the spatiotemporal distribution of Schistosoma(S.)japonicum infections in humans,livestock,and Oncomelania(O.)hupensis across the endemic foci of ***:Based on multi-stage continuous downscaling of sentinel monitoring,county-based schistosomiasis surveillance data were captured from the national schistosomiasis surveillance sites of China from 2005 to *** data included *** infections in humans,livestock,and *** spatiotemporal trends for schistosomiasis were detected using a Joinpoint regression model,with a standard deviational ellipse(SDE)tool,which determined the central tendency and dispersion in the spatial distribution of ***,more spatiotemporal clusters of *** infections in humans,livestock,and *** were evaluated by the Poisson ***:The prevalence of *** human infections decreased from 2.06%to zero based on data of the national schistosomiasis surveillance sites of China from 2005 to 2019,with a reduction from 9.42%to zero for the prevalence of *** infections in livestock,and from 0.26%to zero for the prevalence of *** infections in *** using an SDE tool showed that schistosomiasis-affected regions were reduced yearly from 2005 to 2014 in the endemic provinces of Hunan,Hubei,Jiangxi,and Anhui,as well as in the Poyang and Dongting Lake *** model revealed 11 clusters of *** human infections,six clusters of *** infections in livestock,and nine clusters of *** infections in *** clusters of human infection were highly consistent with clusters of *** infections in livestock and *** were in the 5 provinces of Hunan,Hubei,Jiangxi,Anhui,and Jiangsu,as well as along the middle and lower reaches of the Yangtze ***,livestock,and *** infections with *** were mainly concentrated in the north of the Hunan Province,south of the Hubei Province,north

关键词： Schistosomiasis Sentinel surveillance Spatiotemporal heterogeneity China

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Impacts and Utilization of Electric Vehicles Integration Into Power Systems

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中国电机工程学报 2012年第4期32卷 I0001-I0026页

作者： HUZechun SONG Yonghua XU Zhiwei luo zhuowei ZHAN Kaiqiao JIA Long Tsinghua University

未来电动汽车(plug-in electric vehicle,PEV)的大规模接入,将给电力系统规划和运行带来不可忽视的影响。从电动汽车充电负荷建模与仿真计算、电动汽车接入对电力系统的影响、电动汽车的充放电控制与利用3大方面,讨论电动汽车接入电网... 详细信息

未来电动汽车(plug-in electric vehicle,PEV)的大规模接入,将给电力系统规划和运行带来不可忽视的影响。从电动汽车充电负荷建模与仿真计算、电动汽车接入对电力系统的影响、电动汽车的充放电控制与利用3大方面,讨论电动汽车接入电网的研究现状。指出电动汽车充电负荷分析应考虑的主要因素;总结电动汽车接入对电源发展、电网运行、充电设施与配电网规划方面的影响,并分析电动汽车有序充电及与电网互动(vehicle to grid,V2G)的研究现状和应用难点。最后,对今后的研究方向进行讨论。

关键词：电力系统规划电动汽车集成电动车辆储能装置 EVS 普及率

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Establishment of an indicator framework for the transmission risk of the mountain-type zoonotic visceral leishmaniasis based on the Delphi-entropy weight method

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Infectious Diseases of Poverty 2022年第6期11卷 27-37页

作者： zhuowei luo Zhengbin Zhou Yuwan Hao Jiaxin Feng Yanfeng Gong Yuanyuan Li Yun Huang Yi Zhang Shizhu Li National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research)NHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Centre for Tropical DiseasesNational Center for International Research On Tropical DiseasesShanghai 200025China

Background: Visceral leishmaniasis (VL) is one of the most important neglected tropical diseases. Although VL was controlled in several regions of China during the last century, the mountain-type zoonotic visceral leishmaniasis (MT-ZVL) has reemerged in the hilly areas of China in recent decades. The purpose of this study was to construct an indicator framework for assessing the risk of the MT-ZVL in China, and to provide guidance for preventing ***: Based on a literature review and expert interview, a 3-level indicator framework was initially established in November 2021, and 28 experts were selected to perform two rounds of consultation using the Delphi method. The comprehensive weight of the tertiary indicators was determined by the Delphi and the entropy weight ***: Two rounds of Delphi consultation were conducted. Four primary indicators, 11 secondary indicators, and 35 tertiary indicators were identified. The Delphi-entropy weight method was performed to calculate the comprehensive weight of the tertiary indicators. The normalized weights of the primary indicators were 0.268, 0.261, 0.242, and 0.229, respectively, for biological factors, interventions, environmental factors, and social factors. The normalized weights of the top four secondary indicators were 0.122, 0.120, 0.098, and 0.096, respectively, for climatic features, geographical features, sandflies, and dogs. Among the tertiary indicators, the top four normalized comprehensive weights were the population density of sandflies (0.076), topography (0.057), the population density of dogs, including tethering (0.056), and use of bed nets or other protective measures (0.056).Conclusions: An indicator framework of transmission risk assessment for MT-ZVL was established using the Delphientropy weight method. The framework provides a practical tool to evaluate transmission risk in endemic areas.

关键词： Mountain-type zoonotic visceral leishmaniasis Transmission risk Indicator framework Delphi Entropy weight China

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Epidemiological Features and Spatial-Temporal Clustering of Visceral Leishmaniasis—China,2011–2022

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China CDC weekly 2024年第46期6卷 1201-1205页

作者： Zhengbin Zhou zhuowei luo Gaiqin Pan Yuanyuan Li Zhongqiu Li Qin Liu Yuwan Hao Limin Yang Zelin Zhu Qiang Wang Yi Zhang Shizhu Li National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases National Institute of Parasitic Diseases at Chinese Center for Disease Control and PreventionChinese Center for Tropical Diseases ResearchNHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Center for Tropical DiseasesNational Center for International Research on Tropical DiseasesMinistry of Science and TechnologyChina Beijing Center for Disease Control and Prevention BeijingChina Liaocheng People’s Hospital Liaocheng CityShandong ProvinceChina School of Global Health Chinese Center for Tropical Diseases Research-Shanghai Jiao Tong University School of MedicineShanghaiChina.

What is already known about this topic?Visceral leishmaniasis(VL),transmitted by sandflies,is a zoonotic disease of public health importance in central and western *** is added by this report?A number of VL hotspots were identified in the border areas of Shanxi-Hebei,Shanxi-Shaanxi,Gansu-Sichuan,as well as the southern Xinjiang provinciallevel administrative division(PLAD).Mountain zoonotic visceral leishmaniasis(MT-ZVL)expanded rapidly in the mountainous regions of Shaanxi,Shanxi,Henan,Hebei,Beijing,and Gansu PLADs from 2011 to 2022.A notable resurgence of MT-ZVL has occurred,with 671 cases in 66 historically endemic *** are the implications for public health practice?Actions are recommended to restrain the rapid expansion of MT-ZVL:Firstly,implement One Health approaches,such as timely diagnosis and treatment of patients,promoting insecticide-impregnated dog collars,and restraining the number of dogs in endemic ***,surveillance-response systems for sandflies and infective dogs in potential risk areas should be strengthened.

关键词： restrain expanded Spatial

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AC/DC/AC调频式谐振高压试验电源控制策略

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电力自动化设备 2010年第2期30卷 67-71页

作者：徐先勇罗安方璐刘定国罗卓伟湖南大学电气与信息工程学院湖南长沙410082

传统的调频式谐振高压试验电源采用模拟器件产生幅值、频率可调的正弦信号,由大功率三极管组成的多级放大电路得到大功率正弦信号,电路复杂、不易维护。提出以大功率开关器件IGBT产生局部放电试验或交流耐压试验所需的正弦信号。新型调... 详细信息

传统的调频式谐振高压试验电源采用模拟器件产生幅值、频率可调的正弦信号,由大功率三极管组成的多级放大电路得到大功率正弦信号,电路复杂、不易维护。提出以大功率开关器件IGBT产生局部放电试验或交流耐压试验所需的正弦信号。新型调频式谐振高压试验电源的系统主要由三相PWM整流电路、H桥逆变电路、输出滤波器、检测单元、DSP控制器及人机接口(键盘、液晶)组成。针对电压调节提出应用自适应PI的以电网电流为内环、直流电容电压为外环的双闭环控制策略,对于电压调节由三相PWM整流电路实现;针对频率调节提出应用比例积分锁相自动调频控制策略,频率调节由H桥逆变电路实现。采用Matlab/Simulink仿真工具搭建了系统的仿真模型,仿真及试验结果表明,所提出的控制方案动、静态性能良好,鲁棒性强。

关键词：自适应PI PI锁相控制 PWM整流电路调频式谐振试验电源电源控制策略

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Long noncoding RNA GACAT3 regulates fatty acid metabolism and promotes proliferation by acting as a competing endogenous RNA in gastric cancer

Long noncoding RNA GACAT3 regulates fatty acid metabolism an...

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中国生物化学与分子生物学会第十二届全国会员代表大会暨2018年全国学术会议

作者： Zhen Jiang Daogang Chen Hui Chen Xiaohan Mei Linyu Wang Wenqian Chen zhuowei luo Yaoyao Lu Department of Biochemistry School of Preclinical MedicineNorth Sichuan Medical College

It is widely demonstrated that aberrantly expressed lncRNAs are associated with various cancers,but it is still uncertain how they may become coordinated during the gastric ***,we report that a novel lncRNA GACAT3 regulates the expression of fatty acid synthesis enzyme(FASN) through increasing the expression of miR-497 in gastric *** found that the GACAT3 expression was positively correlated with the TNM staging and lymph node ***,the expression of GACAT3 and FASN were both negatively regulated by ***3 elevates the levels of FASN mRNA by acting as a competing endogenous *** overexpression of GACAT3 promotes cancer cell growth by promoting the G0/G1 to S phase *** summary,the current study highlights some evidence regarding the potential role of GACAT3 in gastric cancer and suggests that GACAT3 can be identified as the candidate target to suppress the carcinogenesis of gastric cancer.

关键词： GACAT3 competing endogenous RNA gastric cancer

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换电模式下电动汽车电池充电负荷建模与有序充电研究

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中国电机工程学报 2012年第31期32卷 1-10,212页

作者：罗卓伟胡泽春宋永华徐智威贾龙电力系统及发电设备控制和仿真国家重点实验室(清华大学电机系) 北京市海淀区100084

为了建立换电模式下电动汽车电池充电负荷及优化模型,对2种电动汽车换电模式即充换电模式和集中充电统一配送模式的结构、运营流程进行了分析。在满足用户换电需求的约束下,基于分时电价机制,提出考虑2种换电方式的以总充电费用最小为... 详细信息

为了建立换电模式下电动汽车电池充电负荷及优化模型,对2种电动汽车换电模式即充换电模式和集中充电统一配送模式的结构、运营流程进行了分析。在满足用户换电需求的约束下,基于分时电价机制,提出考虑2种换电方式的以总充电费用最小为目标的第1阶段优化模型。第2阶段优化以第1阶段求取的最小充电费用为总充电费用的上限,以日负荷曲线波动最小为目标。以中国2020年充电负荷为例进行计算,对不同类型电动汽车采用不同的换电方式,并将换电模式与充电模式的充电负荷进行比较。计算结果表明,换电模式下无序充电情景峰荷较充电模式时增加较小,有序充电情景电网峰荷将不会增加,所提出的换电模式下有序充电模型能够有效减少充电费用及日负荷曲线波动。

关键词：电动汽车电池换电模式电池配送库存管理有序充电

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Study on Charging Load Modeling and Coordinated Charging of Electric Vehicles Under Battery Swapping Modes

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Electricity 2013年第1期24卷 54-54页

作者： luo zhuowei Hu Zechun Song Yonghua Xu Zhiwei Jia Long Tsinghua University

Both State Grid Corporation of China and China Southern Power Grid Corporation have both announced that they were going to promote battery swapping modes to refuel electric vehicles (EVs) in 2011. Building the calculation and optimization model of EV charging load under the battery swap modes is of great significance to study the influence of charging load on power grids. In the paper 'Study on Charging Load Modeling and Coordinated Charging of

关键词：充电电池电动汽车负荷建模中国南方电网公司国家电网公司电网负荷优化模型交换模式

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基于全健康理念的犬源型内脏利什曼病综合治理能力评估指标体系的构建

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中国血吸虫病防治杂志 2023年第6期35卷 545-556页

作者：刘婧姝周正斌张晓溪黄璐璐罗卓韦陈胜林张仪李石柱上海交通大学医学院-国家热带病研究中心全球健康学院上海200025 上海交通大学-爱丁堡大学全健康研究中心上海200025 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心)、国家卫生健康委员会寄生虫病原与媒介生物学重点实验室、WHO热带病合作中心、国家级热带病国际联合研究中心上海200025 北京市疾病预防控制中心

目的基于全健康理念构建犬源型内脏利什曼病(mountain⁃type zoonotic visceral leishmaniasis,MT⁃ZVL)综合治理能力评估指标体系,从全健康的整体视角探索遏制该病疫情回升的切入点,以促进其控制与消除。方法在文献分析基础上,结合课题... 详细信息

目的基于全健康理念构建犬源型内脏利什曼病(mountain⁃type zoonotic visceral leishmaniasis,MT⁃ZVL)综合治理能力评估指标体系,从全健康的整体视角探索遏制该病疫情回升的切入点,以促进其控制与消除。方法在文献分析基础上,结合课题组讨论、现场调查等初步构建指标体系。在北京、河北、山西、河南、四川、陕西、甘肃7个MT⁃ZVL流行省(直辖市)的省级疾病预防控制中心,选择33名专家开展两轮专家咨询,对指标进行筛选,并计算专家积极系数、专家意见集中程度、专家意见协调程度、专家权威程度,采用层次分析法计算各指标归一化权重。结果两轮专家咨询法问卷回收率均为100.00%(33/33),专家权威系数分别为0.86和0.88,指标合理性、重要性、可操作性的专家意见协调系数分别为0.392、0.437、0.258和0.364、0.335、0.263(P均<0.05)。经过筛选,最终形成的指标体系包括3个一级指标、17个二级指标、50个三级指标。“外部环境”、“内部支持”、“综合治理”3个一级指标归一化权重分别为16.98%、38.73%、44.29%;“外部环境”的二级指标中“,自然环境”权重最高(66.67%);“内部支持”的二级指标中,“内脏利什曼病防治科学研究”权重最低(8.26%),其他指标权重在12.42%~13.38%;“综合治理”的二级指标中,各指标权重均为16.67%。结论构建了基于全健康理念的MT⁃ZVL综合治理能力评估指标体系。该指标体系在兼顾传统MT⁃ZVL防治效果评估的同时,综合考虑了顶层设计、组织管理和防治措施落实的重要性,纳入了多部门协作相关指标。

关键词：犬源型内脏利什曼病全健康综合治理能力评估指标体系专家咨询法层次分析法

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Effects of a multi-enzyme complex on growth performance,nutrient utilization and bone mineralization of meat duck

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Journal of Animal Science and Biotechnology 2015年第4期6卷 402-409页

作者： Qiufeng Zeng Xueqin Huang Yuheng luo Xuemei Ding Shiping Bai Jianping Wang Yue Xuan zhuowei Su Yonggang Liu Keying Zhang Institute of Animal Nutrition Key Laboratory for Animal Disease-Resistance Nutrition of China Ministry of EducationSichuan Agricultural University Adisseo Asia Pacific Pte Ltd

Background： Previous studies with broiler have shown dietary supplementation with multi-enzyme complex containing non-starch polysaccharides （NSP） degrading enzymes and phytase is efficient in releasing phosphorus （P）, calcium （Ca）, energy and amino acids from corn-soybean meal diets or corn-sorghum diets, hence compensating considerable levels of nutrients in formulation. Notwithstanding, such potentials have not been well defined in duck nutrition. Giving China being the largest duck producing country, we conducted this study to establish adequate specifications of major nutrients along with multi-enzyme complex to meat duck from day-old to slaughter, focusing on performance, utilization of nutrients and bone mineralization. Five dietary treatments were： Positive control （PC,T1）： the nutrients concentration of diet for 1 to 14 d of age were apparent metabolizable energy（AME） 2,800 kcal/kg, crude protein （CP）1 9.39%, Ca 0.85%, available phosphorus （avP） 0.42%; for 15 to 35 d of age these parameters were AME 2,900 kcal/kg, CP 16.47%,Ca 0.76%,avP 0.38%; Negative control 1（NC1,7-2）, the AME and digestible amino acids （DAA） were reduced by 70 kcal/kg and 2.0%, avP and Ca by 1.0 g/kg from PC diet; Negative control 2（NC2,T4）, the down- spec from PC diet was AME 100 kcal/kg, DAA 2.5%, avP 1.5 g/kg and Ca 1.2 g/kg; The enzyme complex was added at the same dosage （200 mL/1,000 kg） on NC1 （T3） and NC2 （T5） diets. Results： Comparing with the ducks fed on T1, T3 and T5 diets, the birds fed on NC2 diet showed the lowest （P 〈 0.05） body weight （ d 14 and 35）, feed intake （d 35）, tibia ash, Ca and P contents （d 14 and 35）, and the utilization of nutrients （P 〈 0.05）. The supplementation with the enzyme complex to the NC diets restored growth rate, utilization of nutrients and bone mineralization to the level of the PC diet, and increased AME by 60 kcal/kg and 117 kcal/kg, respectively for the NC1 and NC2 diets. Conclusion： These results suggest that down-spec AME by 100 kcal/kg,

关键词： Formulation specification Growth Phytase Meat duck Non-starch polysaccharides enzyme

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