检索结果-南通市图书馆

Discovery of bauxite-type helium source rock in Jinzhong basin, central North China and its resource potential evaluation

第36届中国控制会议

作者： Weirong Chen Youxian Liu zhuo niu Xuexia Zhang School of Electrical Engineering Southwest Jiaotong University

ISBN: (纸本)9781538629185

Optimization of operating parameters on PEMFC to obtain maximum power has a significant role to reduce the costs of this emerging *** this study,the operation parameters of PEMFC are optimized by the orthogonal experiment method and Central composite second order Response Surface Methodology(RSM).Three significant parameters including cathode stoichiometry,anode stoichiometry and control voltage of hydrogen tail gas valve are studied to obtain an optimal cell *** two tests reveal that the effect of air stoichiometric ratio on PEMFC performance is the largest under the high current in the selected range,while the effect of control voltage of hydrogen tail gas valve is the *** the comparison of orthogonal experiment method and RSM,the optimum results show that RSM can be more accurate to predict the maximum power and the optimal values of the operating parameters.

关键词： PEMFC performance optimization orthogonal test RSM

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

China Geology 2023年第4期6卷 753-755页

作者： Qiao Zhang Jun-lin Zhou Yu-hong Li Ya-zhuo niu Wang Guo Shang-wei Ma Yun-peng Zhang Shao-hua Hu Yu Ding Key Laboratory for the Study of Focused Magmatism and Giant Ore Deposits Xi’an CenterChina Geological Survey(Geoscience Innovation Center of Northwest China)Xi’an 710119China Shanxi provincial third institute of geological engineering investigation Jinzhong 030620China

1. Objective Among globally known industrial helium-enriched natural gas reservoirs, associated helium is dominantly crust-derived helium(4He), which is generated by the radioactive decay of uranium(U) and thorium(Th) in crustal rocks. These rocks with old ages are also defined as helium source *** accumulation models for helium have revealed that granite is the main and effective helium source rock in the crust(Li YH et al., 2018).

关键词： globally decay source

Solvent free synthesis of trifluoromethyl tertiary alcohols by cross Aldol reaction

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2015年第8期26卷 1046-1049页

作者： Rui Tao Xue-Jiao Yin Ke-Hu Wang Yu-zhuo niu Ya-Lin Wang Dan-Feng Huang Ying-Peng Su Jin-Xian Wang Yu-Lai Hu Ying Fu Zheng-Yin Du College of Chemistry and Chemical Engineering Northwest Normal University

Exceedingly fast preparation of trifluoromethyl tertiary alcohols has been accomplished from methyl ketones and trifluoromethyl ketones under solvent free conditions by cross Aldol reaction. The reaction was achieved in the presence of common inorganic base by grinding method at ambient temperature to give b-trifluoromethyl-b-hydroxyl ketones in high yields（up to 95%）.

关键词： alcohols tertiary ambient hydroxyl inorganic smoothly accomplished silica heterocyclic reagent

在线全文

学校读者我要写书评

暂无评论

空间直角坐标计算大地纬度的椭球参数变换法

测绘通报 2000年第3期 12-13页

作者：牛卓立中国有色金属工业西安勘察院陕西西安710054

:将地面点或空间点视为在某一辅助椭球面上 ,由该点的空间直角坐标求出其在辅助椭球上的大地纬度和辅助椭球参数 ,再将辅助椭球的大地纬度转换到标准椭球上。

关键词：空间直角坐标大地纬度椭球参数变换法 GPS

Molecular Docking of 3-Methylindole-containing Drugs Binding into CYP3A4

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2012年第1期28卷 137-141页

作者： MENG Xuan-yu, LI zhuo, niu Rui-juan, ZHANG Hong-xing and ZHENG Qing-chuan State Key Laboratory of Theoretical and Computational Chemistry, Institute of Theoretical Chemistry, Jilin University, Changchun 130021, P. R. China Institute of Theoretical Chemistry Jilin University State Key Laboratory of Theoretical and Computational Chemistry Changchun 130021

Drugs SPD-304（6,7-dimethyl-3-{[methyl-（2-{methyl-[1-（3-trifluoromethyl-phenyl）-1H-indol-3-ylme thyl]-amino}-ethyl）-amino]-methyl}-chromen-4-one） and zafirlukast contain a common structural element of 3-substituted indole moiety which closely relates to a dehydrogenated reaction catalyzed by cytochrome P450s（CYPs）. It was reported that the dehydrogenation can produce a reactive electrophilic intermediate which cause toxicities and inactivate CYPs. Drug L-745,870（3-{[4-（4-chlorophenyl）piperazin-1-yl]-methyl}-1H-pyrrolo 2,3-β-pyridine） might have similar effect since it contains the same structural element. We used molecular docking approach combined with molecular dynamics（MD） simulation to model three-dimensional（3D） complex structures of SPD-304, zafirlukast and L-745,870 into CYP3A4, respectively. The results show that these three drugs can stably bind into the active site and the 3-methylene carbons of the drugs keep a reasonable reactive distance from the heme iron. The complex structure of SPD-304-CYP3A4 is in agreement with experimental data. For zafirlukast, the calcu lation results indicate that 3-methylene carbon might be the dehydrogenation reaction site. Docking model of L-745,870-CYP3A4 shows a potential possibility of L-745,870 dehydrogenated by CYP3A4 at 3-methylene carbon which is in agreement with experiment in vivo. In addition, residues in the phenylalanine cluster as well as S119 and R212 play a critical role in the ligands binding based on our calculations. The docking models could provide some clues to understand the metabolic mechanism of the drugs by CYP3A4.

关键词： CYP3A4 Molecular docking Molecular dynamics(MD) simulation

护理干预对急性闭角型青光眼伴焦虑抑郁患者眼压及焦虑抑郁评分的影响

在线全文

学校读者我要写书评

暂无评论

中国初级卫生保健 2017年第11期31卷 76-77页

作者：牛卓娅南阳医学高等专科学校第一附属医院眼科河南南阳473000

目的探讨护理干预对急性闭角型青光眼患者围手术期的护理效果。方法选取146例急性闭角型青光眼患者随机分为观察组和对照组,每组各73例。对照组施以常规护理,观察组在对照组的基础上进行优化护理干预。结果观察组患者的眼压、护理满意... 详细信息

目的探讨护理干预对急性闭角型青光眼患者围手术期的护理效果。方法选取146例急性闭角型青光眼患者随机分为观察组和对照组,每组各73例。对照组施以常规护理,观察组在对照组的基础上进行优化护理干预。结果观察组患者的眼压、护理满意度均明显优于对照组,差异有统计学意义(P<0.05)治疗后两组HAMA及HAMD评分均明显下降,且观察组HAMA及HAMD评分明显低于对照组(P<0.05)。结论对闭角型青光眼患者给予的优化护理干预措施,可以有效改善的临床症状,减轻患者病痛,改善患者的焦虑及抑郁状态,提高患者的护理满意度,使患者尽快恢复,从身心双重角度回归社会,值得临床借鉴。

关键词：急性闭角型青光眼围手术期优化护理干预

在线全文

学校读者我要写书评

暂无评论

元代书院藏书述略

河北青年管理干部学院学报 2007年第2期19卷 64-66页

作者：牛卓丽河北青年管理干部学院河北石家庄050031

由于统治者对文化教育事业的日益重视,元代官办、民办书院均得到较快发展,书院藏书随之呈现新气象;书院藏书源于继承、自行刻印、购置与私人捐赠;书院藏书发展中出现了一些特有现象,如书院官学化造成的影响、联合刊刻大型图书等;其发展... 详细信息

由于统治者对文化教育事业的日益重视,元代官办、民办书院均得到较快发展,书院藏书随之呈现新气象;书院藏书源于继承、自行刻印、购置与私人捐赠;书院藏书发展中出现了一些特有现象,如书院官学化造成的影响、联合刊刻大型图书等;其发展得益于一系列开明政策与客观条件。

关键词：元代书院藏书

在线全文

学校读者我要写书评

暂无评论

简述隋代佛经目录的发展

河北青年管理干部学院学报 2008年第4期20卷 57-59页

作者：牛卓丽河北青年管理干部学院河北石家庄050031

由于隋朝的统一、社会经济的发展、统治者的重视、魏晋南北朝时期佛经目录学的进步等多种因素,隋代的佛经文献数量巨增,译经、写经、印经事业均取得较大进步,对佛经的整理成为当务之急,出现一批质量较高的佛经目录,其类型、体例趋于完善... 详细信息

由于隋朝的统一、社会经济的发展、统治者的重视、魏晋南北朝时期佛经目录学的进步等多种因素,隋代的佛经文献数量巨增,译经、写经、印经事业均取得较大进步,对佛经的整理成为当务之急,出现一批质量较高的佛经目录,其类型、体例趋于完善,在中国佛经目录学史上起到了承前启后的作用,具有重要的历史地位。

关键词：隋代佛经目录发展

在线全文

学校读者我要写书评

暂无评论

浅议高校图书馆学生借阅权利的最大化

河北青年管理干部学院学报 2006年第3期18卷 111-112,F0003页

作者：牛卓丽河北青年管理干部学院河北石家庄050031

高校图书馆要实现学生借阅权利最大化,应考虑以下因素:真正贯彻平等原则,保证学生使用馆藏资源的平等地位;以对学生提供最佳服务为第一要务,努力研究并满足学生借阅需求;从“以书为本”向“以人为本”转变,实现馆藏文献的最大程度开放;... 详细信息

高校图书馆要实现学生借阅权利最大化,应考虑以下因素:真正贯彻平等原则,保证学生使用馆藏资源的平等地位;以对学生提供最佳服务为第一要务,努力研究并满足学生借阅需求;从“以书为本”向“以人为本”转变,实现馆藏文献的最大程度开放;实行人性化管理,以“强调权利性”规章制度取代原来的“强调义务性”制度,以充分体现人文关怀。

关键词：高校图书馆学生借阅权利最大化