检索结果-南通市图书馆

Highly-Sensitive Multiplexed in vivo Imaging Using PEGylated Upconversion Nanoparticles

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2010年第10期3卷 722-732页

作者： liang Cheng Kai Yang Shuai Zhang Mingwang Shao Shuittong Lee zhuang Liu Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices Institute of Functional Nano and Soft MaterialsSoochow UniversitySuzhouJiangsu 215123China Center of Super-Diamond and Advanced Films(COSDAF)and Department of Physics and Materials Science City University of Hong KongHong KongChina

Lanthanide-based upconversion nanoparticles(UCNPs)have been widely explored in various fields,including optical imaging,in recent *** earlier work has shown that UCNPs with different lanthanide(Ln3+)dopants exhibit various colors,multicolor-especially in vivo multiplexed biomedical imaging-using UCNPs has rarely been *** this work,we synthesize a series of UCNPs with different emission colors and functionalize them with an amphiphilic polymer to confer water *** in vivo upconversion luminescence(UCL)imaging is demonstrated by imaging subcutaneously injected UCNPs and applied in multiplexed in vivo lymph node *** also use UCNPs for multicolor cancer cell labeling and realize in vivo cell tracking by UCL ***,for the first time we compare the in vivo imaging sensitivity of quantum dot(QD)-based fluorescence imaging and UCNP-based UCL imaging side by side,and find the in vivo detection limit of UCNPs to be at least one order of magnitude lower than that of QDs in our current non-optimized imaging *** data suggest that,by virtue of their unique optical properties,UCNPs have great potential for use in highly-sensitive multiplexed biomedical imaging.

关键词： Upconversion nanoparticles multicolor imaging lymphatic mapping cell tracking sensitive imaging

Assessment of Spinal Tumor Treatment Using Implanted 3D-Printed Vertebral Bodies with Robotic Stereotactic Radiotherapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Innovation 2020年第2期1卷 8-12,7页

作者： Hongqing zhuang Feng Wei liang Jiang Yuxia Wang Zhongjun Liu Department of Radiation Oncology Peking University Third Hospital49 North Garden RoadHaidian DistrictBeijing 100191P.R.China Orthopedic Department Peking University Third Hospital49 North Garden RoadHaidian DistrictBeijing 100191P.R.China These authors contributed equally

To investigate the feasibility and early efficacy of 3D-printed vertebral body implantation combined with robotic radiosurgery in the treatment of spinal *** study included 14 patients with spinal tumors from December 2017 to June *** surgery,all patients were subjected to CT scan and 3D data of the corresponding vertebral segments were *** alloy formed 3D-printed vertebral body implantation and robotic stereotactic radiotherapy were performed because of the risk of postoperative residual,high risk of recovery,or recurrence after *** main outcomes included the remission of symptoms,vertebral body stability,robotic stereotactic surgical precision,and local tumor *** patients received complete and successful combination therapy,and all healed primarily without complica*** error of the coverage accuracy for robotic radiosurgery was less than 0.5 mm,and the error of the rotation angle was less than 0.5.The therapeutic toxicity was limited(mainly in grades 1–2),and adverse events were *** evaluation of vertebral body stability and histocompatibility for all patients met the postoperative clinical *** patients with post spinal injury,the pain symptoms were reduced or disappeared(93%),and nerve function was improved or even recovered after treatment(100%).During our follow-up period,most tumors were locally well controlled(93%).3D-printed vertebral body implantation combined with robotic radiosurgery may offer a new treatment of spinal *** clinical trial registry:ChiCTR-ONN-17013946.

关键词： 3D-PRINTED TECHNOLOGY SPINAL TUMOR VERTEBRAL BODY IMPLANTATION ROBOTIC STEREOTACTIC RADIOTHERAPY

基于机器学习与红外光谱技术的变压器油老化行为研究

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

光谱学与光谱分析 2025年第2期45卷 434-442页

作者：肖忠良袁荣耀付壮刘成尹碧露肖敏之赵亭亭匡尹杰宋刘斌长沙理工大学化学化工学院湖南长沙410114

为解决现阶段油品老化分析工作复杂、误差大等问题,提出一种红外光谱与机器学习(ML)相融合的技术。借助傅里叶变换中红外(FT-MIR)光谱仪采集三种变压器油在不同老化时间的样本光谱,运用多种预处理方法对样本光谱进行预处理,以自动寻峰... 详细信息

为解决现阶段油品老化分析工作复杂、误差大等问题,提出一种红外光谱与机器学习(ML)相融合的技术。借助傅里叶变换中红外(FT-MIR)光谱仪采集三种变压器油在不同老化时间的样本光谱,运用多种预处理方法对样本光谱进行预处理,以自动寻峰并求得特征峰面积之和。采用偏最小二乘回归(PLSR)和粒子群优化-支持向量机回归(PSO-SVR)算法建立了变压器油老化程度定量分析模型,研究并分析了多种光谱数据预处理方法对红外光谱降噪、基线校正等处理效果以及对两种模型定量分析效果的影响。结果表明,油品光谱预处理效果最好的是平滑法,其中SG+SVR和SG+PLSR模型拟合优度(R^(2))分别为0.9814、0.9913,平均绝对误差(MAE)为0.3124、0.2880,均方根误差(RMSE)仅有0.0977、0.3790。在合适的预处理条件下,两种机器学习算法鲁棒性和可靠性均较强,模型预测值与实际值间差异极小。

关键词：机器学习傅里叶变换中红外光谱变压器油老化程度粒子群优化-支持向量机回归(PSO-SVR) 偏最小二乘回归(PLSR)

维普期刊数据库

Modification of the CuO electronic structure for enhanced selective electrochemical CO_(2) reduction to ethylene

在线全文

学校读者我要写书评

暂无评论

Nano Research 2024年第8期17卷 7194-7202页

作者： Xin Wu zhuang Tong Yunliang Liu Yaxi Li Yuanyuan Cheng Jingwen Yu Peng Cao Chunqiang zhuang Qiuzhong Shi Naiyun Liu Xiang Liu Hongyu liang Haitao Li Institute for Energy Research School of Energy and Power EngineeringJiangsu UniversityZhenjiang 212013China Faculty of Materials and Manufacturing Beijing University of TechnologyBeijing 100124China Institute of Medicine&Chemical Engineering Zhenjiang CollegeZhenjiang 212013China Institute of Advanced Manufacturing and Modern Equipment Technology School of Mechanical EngineeringJiangsu UniversityZhenjiang 212013China

Electrochemical carbon dioxide reduction reaction(CO_(2)RR)can produce value-added hydrocarbons from renewable electricity,providing a sustainable and promising approach to meet dual-carbon targets and alleviate the energy ***,it is still challenging to improve the selectivity and stability of the products,especially the C^(2+) *** we propose to modulate the electronic structure of copper oxide(CuO)through lattice strain construction by zinc(Zn)doping to improve the selectivity of the catalyst to *** performance and in situ characterization analyses show that the compressive strain generated within the CuO lattice and the electronic structure modulation by Zn doping enhances the adsorption of the key intermediate*CO,thereby increasing the intrinsic activity of CO_(2)RR and inhibiting the hydrogen precipitation *** the best catalysts had significantly improved ethylene selectivity of 60.5%and partial current density of 500 mA·cm^(–2),and the highest C^(2+) Faraday efficiency of 71.47%.This paper provides a simple idea to study the modulation of CO_(2)RR properties by heteroatom doped and lattice strain.

关键词： CO_(2) reduction heteroatom-doped lattice strain ethylene selectivity

Design, Synthesis and Antifungal Activity of Benzofuran and Its Analogues

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2019年第12期37卷 1245-1250页

作者： Hang Xu zhuang Hou Zhen liang Meng-Bi Guo Xin Su Chun Guo School of Pharmaceutical Engineering Shenyang Pharmaceutical UniversityShenyangLiaoning 110016China School of life sciences and biological pharmacy Shenyang Pharmaceutical UniversityShenyangLiaoning 110016China

Summary of main observation and conclusion Benzofuran has antifungal activity as the inhibitor of ***-nine novel benzofuran-semicarbazide hybrids were designed and synthesized by principle of drug *** this basis,the benzofuran ring was simplified to a resorcinol structure,and sixteen novel 1,3-dialkoxybenzene-semicarbazide hybrids were designed and *** structures of the target compounds were characterized by HRMS and *** in vitro antifungal activity of target compounds was evaluated using the microdilution broth method against eight strains of pathogenic fungi with fluconazole as positive *** to the results of the target compounds,structure-activity relationship(SAR)is *** inhibitory activity against the tested strains of simplified compounds(K01-K16)has different levels improvement compared with compounds Z01-Z29.K01-K16 showed significant antifungal activities against ***,***,and sensitive *** ***,compounds Z20,Z22,K10,K11 and K16 also displayed different activities against two fluconazole-resistance strains that were isolated from AIDS *** minimal inhibitory concentration(MIC)values against fluconazole-resistant strains were in the range of 2-8μg/mL and 4-32μg/mL,***,molecular docking was performed to investigate the binding affinities and interaction modes between the target compound and N-myristoyltransferase.

关键词： simplified furan azide

A flexible multi-16QAM transmitter based on cascaded dual-parallel Mach-Zehnder modulator and phase modulator

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Technological Sciences 2013年第3期56卷 598-602页

作者： ZHANG liang HU XiaoFeng CAO Pan zhuang ZhiMing JIANG XinHong SU YiKai State Key Laboratory of Advanced Optical Communication Systems and Networks Department of Electronic EngineeringShanghai Jiao Tong University

In this paper,we propose a novel and flexible 16-quadrature amplitude modulation(16QAM) transmitter based on cascaded dual-parallel Mach-Zehnder modulator(DPMZM) and phase modulator(PM).The proposed transmitter is able to generate three types of 16QAM signals:square 16QAM,star 16QAM and four-amplitude-four-phase-16-QAM(FAFP-16QAM).The feasibility of the transmitter is verified through experiment,20-Gb/s eye diagrams of the 16QAM signals are *** order to evaluate the performances of the 16QAM signals,simulations are also conducted using VPI Transmission Maker,clear constellations of 40-Gb/s 16QAM signals are achieved by coherent detection.

关键词： 16QAM optical communication Mach-Zehnder modulator(MZM) phase modulator(PM) multi-level format

Theoretical insights into nitrogen oxide activation on halogen defect-rich{001}facets of bismuth oxyhalide

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2021年第18期77卷 217-222页

作者： Kang Xu liang Wang Haifeng Feng Zhongfei Xu Jincheng zhuang Yi Du Feng Pan Weichang Hao BUAA-UOW Joint Centre School of PhysicsBeihang UniversityHaidian DistrictBeijing100191China Institute for Superconducting and Electronic Materials(ISEM) Australian Institute for Innovative Materials(AIIM)University of WollongongWollongongNSW2525Australia Research Institute for Frontier Science of Beihang University Haidian DistrictBeijing100191China Beijing Computational Science Research Center Beijing100193China

Surface vacancies,serving as the activation centers for surface-adsorbed species,have been widely applied in catalysts to improve their activity and *** the case of ternary compound semiconductors,there is some controversy about exposed atoms and surface ***-dimensional layered BiOCl is an important photocatalyst,which has had numerous studies focused on its oxygen vacancy(O_V)and bismuth vacancy(Bi_V).It has been realized that its(001)surface can consist of exposed halogen atoms rather than oxygen atoms,which thus needs a new explanation for its surface defect engineering *** first-principles calculations,the activation behavior of NO_X(NO_(2),NO,N_(2)O)at a chlorine vacancy(Cl_V)on the BiOCl(001)surface is systematically *** is found that after introducing Cl_V on BiOCl(001)surfaces,NO_X molecules all show excellent activities with longer chemical bonds by capturing electrons from the *** work furnishes fundamental insight into the activation of small molecules on defect-rich surfaces of ternary compound catalysts.

关键词： BiOCl Surface chlorine vacancy NO_X(NO_(2)NON_(2)O)molecules Selective reduction

维普期刊数据库

Signal acquisition of Luojia-1A low earth orbit navigation augmentation system with software defined receiver

在线全文

学校读者我要写书评

暂无评论

Geo-Spatial Information Science 2022年第1期25卷 47-62页

作者： liang Chen Xiangchen Lu Nan Shen Lei Wang Yuan zhuang Ye Su Deren Li Ruizhi Chen State Key Laboratory Of Information Engineering In Surveying Mapping And Remote SensingWuhan UniversityWuhanChina

Low Earth Orbit(LEO)satellite navigation signal can be used as an opportunity signal in the case of a Global Navigation Satellite System(GNSS)outage,or as an enhancement by means of traditional GNSS positioning *** matter which service mode is used,signal acquisition is a prerequisite for providing enhanced LEO navigation *** with the medium orbit satellite,the transit time of the LEO satellite is ***,it is of great significance to expand the successful acquisition time range of the LEO *** studies on LEO signal acquisition are based on simulation ***,signal acquisition research based on real data is *** this work,the signal characteristics of LEO satellites:power space density in free space and the Doppler shift of LEO satellites are individually *** unified symbolic definitions of several integration algorithms based on the parallel search signal acquisition algorithm are *** verify these algorithms for LEO signal acquisition,a Software Defined Receiver(SDR)is *** performance of these integration algorithms on expanding the successful acquisition time range is verified by the real data collected from the Luojia-1A *** experimental results show that the integration strategy can expand the successful acquisition time range,and it will not expand indefinitely with the integration *** performance of the coherent integration and differential integration algorithms is better than the other two integration algorithms,so the two algorithms are recommended for LEO signal acquisition and a 20 ms integration duration is *** detection threshold of 2.5 is not suitable for all integration algorithms and various integration durations,especially for the Maximum-to-Mean Ratio indicator.

关键词： Coherent integration differential coherent integration Low Earth Orbit(LEO) non-coherent integration navigation augmentation signal acquisition

CuZnAl-MMO复合纳米抗菌薄膜对樱桃保鲜效果的影响

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

食品科学技术学报 2025年第1期43卷 126-136页

作者：庄良王平飞陈立石孟童罗倩何杉张桂菊徐宝财北京工商大学轻工科学技术学院北京100048

樱桃采后易腐烂且易被微生物感染,而传统保鲜方法具有潜在毒性和化学残留等缺点。为了解决这一问题,采取有机无机杂化策略,构建由CuZnAl复合金属氧化物(CuZnAl-MMO)纳米粒子增强的壳聚糖(CS)和聚乙烯醇(PVA)的复合纳米薄膜。通过分析纳... 详细信息

樱桃采后易腐烂且易被微生物感染,而传统保鲜方法具有潜在毒性和化学残留等缺点。为了解决这一问题,采取有机无机杂化策略,构建由CuZnAl复合金属氧化物(CuZnAl-MMO)纳米粒子增强的壳聚糖(CS)和聚乙烯醇(PVA)的复合纳米薄膜。通过分析纳米薄膜的形态结构、力学性能、疏水性能和阻隔性能,证明了CuZnAl-MMO与CS/PVA发生了自组装,增强了纳米薄膜的力学性能和疏水性。相较于CS/PVA-0%MMO纳米薄膜,CS/PVA-6%MMO纳米薄膜的拉伸强度增加了35%,接触角从43.4°上升到了67.9°。此外,CS/PVA-6%MMO纳米薄膜的水蒸气透过率和氧气透过率比CS/PVA-0%MMO纳米薄膜分别下降了43.2%和80.3%。这是由于自组装过程导致了薄膜内碳链通道的重组,从而提高了阻隔性能。这种重组促进了有利于樱桃储存的微环境的形成,既提高了纳米薄膜的防潮性,又促进了气体改良气氛的形成。研究发现,随着CuZnAl-MMO在纳米薄膜中含量的逐渐增加,纳米薄膜对革兰氏阴性菌大肠杆菌、革兰氏阳性菌金黄色葡萄球菌和灰霉菌的抗菌性能逐渐增强。樱桃保鲜实验结果显示,纳米薄膜能够显著降低坏果率、失重率以及樱桃表面的总菌落数,同时延缓了硬度的下降。纳米薄膜还改善了樱桃的呼吸频率,使得包装袋内的CO_(2)体积分数升高至16.1%。在纳米薄膜内成功促进气体改良气氛形成对樱桃的保存非常有利。CuZnAl-MMO复合纳米薄膜对微生物的抑制效果和对樱桃保鲜性能的提升表明,这种新型保鲜方法具有一定的应用前景。研究旨在为CuZnAl-MMO复合纳米薄膜在果蔬保鲜领域的应用提供一定的理论基础。

关键词：水滑石纳米薄膜自组装多元抗菌中心樱桃保鲜

维普期刊数据库