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Progress on Bionic Textured Cutting Tools:A Review and Prospects

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Journal of Bionic Engineering 2024年第1期21卷 19-55页

作者： Hong Wei Guangjun chen zhuang chen Zhiwei Yu Jiashuai Huang Tianjin Key Laboratory of High Speed Cutting and Precision Processing Tianjin 300222China School of Mechanical Engineering Tianjin University of Technology and EducationTianjin 300222China

Cutting tools are known as the“productivity”of the manufacturing industry,which affects the production efficiency and quality of the workpiece,and has become the focus of research and attention in academia and ***,traditional cutting tools often suffer from adhesion or wear during the cutting process,which considerably reduces the cutting efficiency and service life of the tools,and makes it difficult to meet current production *** solve the above problems,scholars have introduced bionics into the tool’s design,applying the microscopic structure of the biological surface to the tool surface to alleviate the tool’s *** paper mainly summarizes the research progress of bionic textured cutting ***,categorize whether the bionic texture design is inspired by a single organism or multiple ***,it is discussed that the non-smooth surface of the biological surface has five characteristics:hydrophilic lubricity,wear resistance,drag reduction and hydrophobicity,anti-adhesion,and arrangement,and the non-smooth structure of these different characteristics are applied to the surface of the tool is designed with bionic ***,the cutting performance of bionic textured cutting tools is *** anti-friction and wear-resisting mechanism of bionic textured cutting tools is ***,some pending problems and perspectives have been proposed to provide new inspirations for the design of bionic textured cutting tools.

关键词： Bionic textured cutting tools Biological microstructure characteristics Cutting performance Anti-friction and wear-resisting mechanism

Engineered extracellular vesicles: A new approach for targeted therapy of tumors and overcoming drug resistance

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Cancer Communications 2024年第2期44卷 205-225页

作者： chen Ming-Kun chen Zi-Xian Cai Mao-Ping chen Hong chen zhuang-Fei Zhao Shan-Chao Department of Urology The Third Affiliated Hospital of Southern Medical UniversityGuangzhouGuangdongP.R.China The Third Clinical College Southern Medical UniversityGuangzhouGuangdongP.R.China Luoyang Key Laboratory of Organic Functional Molecules College of Food and DrugLuoyang Normal UniversityLuoyangHenanP.R.China Department of Urology Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdongP.R.China

Targeted delivery of anti-tumor drugs and overcoming drug resistance in malig-nant tumor cells remain significant clinical ***,there are only few effective methods to address these *** vesicles(EVs),actively secreted by cells,play a crucial role in intercellular information transmis-sion and cargo *** studies have demonstrated that engineered EVs can serve as drug delivery carriers and showed promising application ***,there is an urgent need for further improvements in the isolation and purification of EVs,surface modification techniques,drug assem-bly processes,and precise recognition of tumor cells for targeted drug delivery *** this review,we summarize the applications of engineered EVs in cancer treatment and overcoming drug resistance,and current challenges asso-ciated with engineered EVs are also *** review aims to provide new insights and potential directions for utilizing engineered EVs as targeted delivery systems for anti-tumor drugs and overcoming drug resistance in the near future.

关键词： drug delivery drug resistance extracellular vesicles nanoparticles

Enhancing Offensive Language Detection with Data Augmentation and Knowledge Distillation

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Research 2024年第2期6卷 29-40页

作者： Jiawen Deng zhuang chen Hao Sun Zhexin Zhang Jincenzi Wu Satoshi Nakagawa Fuji Ren Minlie Huang The CoAl group DCSTInstitute for Artificial InteligenceState Key Lab of Intelligent Technology and SystemsBeijing National Research Center for Information Science and TechnologyTsinghua UniversityBeijing 100084China Graduate School of Information Science&Technology The University of Tokyo.Tokyo 1138654Japan School of Computer Science and Engineering University of Electronic Science and Technology of ChinaChengduSichuan611731China

Offensive language detection has received important attention and plays a crucial role in promoting healthy communication on social platforms,as well as promoting the safe deployment of large language *** data is the basis for developing detectors;however,the available offense-related dataset in Chinese is severely limited in terms of data scale and coverage when compared to English *** significantly affects the accuracy of Chinese offensive language detectors in practical applications,especially when dealing with hard cases or out-of-domain *** alleviate the limitations posed by available datasets,we introduce AugCOLD(Augmented Chinese Offensive Language Dataset),a large-scale unsupervised dataset containing 1 million samples gathered by data crawling and model ***,we employ a multiteacher distillation framework to enhance detection performance with unsupervised *** is,we build multiple teachers with publicly accessible datasets and use them to assign soft labels to *** soft labels serve as a bridge for knowledge to be distilled from both AugCOLD and multiteacher to the student network,i.e.,the final offensive *** conduct experiments on multiple public test sets and our well-designed hard tests,demonstrating that our proposal can effectively improve the generalization and robustness of the offensive language detector.

关键词： COLD dealing limitations

Effects of extracellular vesicle-derived noncoding RNAs on pre-metastatic niche and tumor progression

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Genes & Diseases 2024年第1期11卷 176-188页

作者： zhuang chen Qiming Wang Jinbo Liu Wenkang Wang Weitang Yuan Yang Liu Zhenqiang Sun chengzeng Wang Department of Colorectal Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450052China Academy of Medical Sciences of Zhengzhou University ZhengzhouHenan 450001China Department of Internal Medicine Affiliated Cancer Hospital of Zhengzhou UniversityHenan Cancer HospitalZhengzhouHenan 450008China Department of Breast Surgery The First Affliated Hospital of Zhengzhou UniversityZhengzhouHenan 450052China Department of Radiotherapy Affiliated Cancer Hospital of Zhengzhou UniversityHenan Cancer HospitalZhengzhouHenan 450008China The First Affiliated Hospital of Zhengzhou University ZhengzhouHenan 450052China

A pre-metastatic niche(PMN)is a protective microenvironment that facilitates the colonization of disseminating tumor cells in future metastatic *** vesicles(EVs)play a role in intercellular communication by delivering cargoes,such as noncoding RNAs(ncRNAs).The pivotal role of extracellular vesicle-derived noncoding RNAs(EV-ncRNAs)in the PMN has attracted increasing *** this review,we summarized the effects of EV-ncRNAs on the PMN in terms of immunosuppression,vascular permeability and angiogenesis,inflammation,metabolic reprogramming,and fibroblast *** particular,we provided a comprehensive overview of the effects of EV-ncRNAs on the PMN in different ***,we discussed the promising clinical applications of EV-ncRNAs,including their potential as diagnostic and prognostic markers and therapeutic targets.

关键词： Biomarker Extracellular vesicles Noncoding RNAs

三维线接触微动界面疲劳寿命预测及断裂行为研究

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机械工程学报 2024年第8期60卷 107-120页

作者：董庆兵陈壮罗振涛张杰魏静重庆大学机械传动国家重点实验室重庆400044 重庆大学机械与运载工程学院重庆400044 西南石油大学机电工程学院成都610500

工程机械中常用的连接结构由两个或多个零件紧密配合而成,在运行过程中接触的零件相互挤压的同时伴随有小幅相对滑动,易发生微动疲劳。微动疲劳主要分为疲劳裂纹萌生、疲劳裂纹扩展和快速断裂三个阶段,连接结构中的零件断裂可引起严重... 详细信息

工程机械中常用的连接结构由两个或多个零件紧密配合而成,在运行过程中接触的零件相互挤压的同时伴随有小幅相对滑动,易发生微动疲劳。微动疲劳主要分为疲劳裂纹萌生、疲劳裂纹扩展和快速断裂三个阶段,连接结构中的零件断裂可引起严重事故。现有的研究主要基于经过简化的二维平面应变模型,为了更清楚地了解微动疲劳的断裂机制,首先建立了微动条件下的三维线接触有限元模型,然后基于临界平面法分析了裂纹萌生寿命、位置和角度,最后基于线弹性断裂力学模拟了三维疲劳裂纹扩展过程。结果表明:在微动载荷的作用下,裂纹以一定倾斜角度在接触区域边缘处萌生,先沿着萌生方向逐渐扩展,当疲劳裂纹扩展至一定深度时,在循环体应力作用下,其方向逐渐变为垂直于接触表面,最终使试件断裂。裂纹萌生阶段的寿命远大于扩展阶段的寿命,占微动疲劳寿命的70%~80%。计算得到的疲劳寿命与文献中微动试验的寿命结果在2倍的分散带内,验证了该方法的有效性。该仿真分析方法可为连接结构的抗微动疲劳设计提供理论基础。

关键词：微动接触部分滑移多轴疲劳临界平面法疲劳断裂

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螺杆灌注桩在某高层项目中的应用

福建建设科技 2024年第1期 126-128,133页

作者：庄晨福州市建筑设计院有限责任公司福建福州350109

建筑桩基大多采用预应力管桩和灌注桩,前者出现的质量问题较多,后者造价较高,寻找新的桩基类型成为具有实际意义的一个工程问题。本文对一种较为新型的桩型——螺杆灌注桩的受力原理、设计、施工重点及在某高层项目中应用的情况做了详... 详细信息

建筑桩基大多采用预应力管桩和灌注桩,前者出现的质量问题较多,后者造价较高,寻找新的桩基类型成为具有实际意义的一个工程问题。本文对一种较为新型的桩型——螺杆灌注桩的受力原理、设计、施工重点及在某高层项目中应用的情况做了详细介绍,供工程设计人员参考。

关键词：螺杆灌注桩受力原理设计施工高层建筑

显微共聚焦激光拉曼光谱结合PCA-HCA-LDA对便签纸的识别分类

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应用激光 2024年第2期44卷 94-103页

作者：陈壮贾成贺姜红甘肃政法大学司法警察学院(公安分院) 甘肃兰州730070 中国政法大学证据科学研究院北京100080 新疆维吾尔自治区公安厅科技信息化总队新疆乌鲁木齐830000 甘肃警察职业学院刑事侦查系甘肃兰州730046

建立便签纸物证快速、准确的识别分类模型,为基层公安获取线索提供数据和理论依据。利用显微共聚焦激光拉曼光谱法(LCM-Raman)检验44个便签纸样品,结合主成分分析(PCA)、系统聚类(HCA)和线性判别分析(LDA)实现便签纸样品识别分类。依据... 详细信息

建立便签纸物证快速、准确的识别分类模型,为基层公安获取线索提供数据和理论依据。利用显微共聚焦激光拉曼光谱法(LCM-Raman)检验44个便签纸样品,结合主成分分析(PCA)、系统聚类(HCA)和线性判别分析(LDA)实现便签纸样品识别分类。依据样品中无机填料的拉曼光谱特征峰的不同,对样品进行定性分析并初步分为19类。为了更加科学准确地对样品进行分类,利用主成分分析对样品拉曼光谱数据降维,并利用系统聚类结合线性判别分析确定样品最佳分类为4类。结果表明,LCM-Raman结合PCA-HCA-LDA分类模型可区分便签纸样品,分类结果科学准确。

关键词：光谱学显微共聚焦激光拉曼光谱法主成分分析系统聚类线性判别分析便签纸

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革命文化融入高校思想政治教育的多维考察

淮北职业技术学院学报 2024年第3期23卷 21-25页

作者：陈庄温州大学马克思主义学院浙江温州325035

习近平新时代中国特色社会主义思想是革命文化融入高校思想政治教育的重要理论依据。革命文化融入高校思想政治教育不仅有着厚植学生爱国主义情怀和提高革命历史认知的基本价值,还具有回应思想政治教育主要原则和丰富教学形式与内容的... 详细信息

习近平新时代中国特色社会主义思想是革命文化融入高校思想政治教育的重要理论依据。革命文化融入高校思想政治教育不仅有着厚植学生爱国主义情怀和提高革命历史认知的基本价值,还具有回应思想政治教育主要原则和丰富教学形式与内容的逻辑理路。将革命文化融入高校思想政治教育管理及教学全过程,融入高校思想政治育人工作与网络载体的各环节之中,有助于更好地发挥高校思想政治教育实效。

关键词：革命文化高校思想政治教育育人价值教学方法

他者、杂糅与翻译:后现代视域下英汉融合双关语翻译研究

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上海理工大学学报（社会科学版） 2024年第2期46卷 89-98页

作者：祝朝伟陈壮四川外国语大学翻译学院四川重庆400031 巴伊兰大学英语文学与语言学系拉马甘529002 湖北经济学院外国语学院湖北武汉430205

后现代思潮对异质性、互文性的强调在翻译研究中掀起了一场全方位的认知革命。解构主义、后殖民主义、女权主义翻译观使翻译研究者开始关注传统翻译互动中两种类型的“他者”:传统二元等级结构中作为弱势群体的“他者”和在二元临界地... 详细信息

后现代思潮对异质性、互文性的强调在翻译研究中掀起了一场全方位的认知革命。解构主义、后殖民主义、女权主义翻译观使翻译研究者开始关注传统翻译互动中两种类型的“他者”:传统二元等级结构中作为弱势群体的“他者”和在二元临界地带流浪的游离性“他者”。长期以来,翻译学界对第一类“他者”给予了充分的关注,但对处于二元临界地带流浪的游离性“他者”并未引起足够的重视。作为游离性“他者”在文本层面的典型体现,英汉融合双关语这一新型杂糅文本逐渐兴起并已进入中国大众的日常生活,却并未在学界得到应有的关注。该类文本不可通约的“他者性”和“创造性”特质有利于人们重新思考翻译的定义、可译性和翻译伦理问题,为后现代翻译研究提供新的视角。

关键词：互文性差异性后现代杂糅文本英汉融合双关语翻译研究