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Diagnosis,treatment and prevention of severe acute respiratory syndrome coronavirus 2 infection in children:experts'consensus statement updatedforthe Omicron variant

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World Journal of Pediatrics 2024年第3期20卷 272-286页

作者： Rong-Meng Jiang Zheng-De Xie Yi Jiang Xiao-Xia Lu Run-Ming Jin Yue-Jie Zheng Yun-Xiao Shang Bao-Ping Xu Zhi-Sheng Liu Gen Lu Ji-Kui Deng Guang-Hua Liu Xiao-Chuan Wang Jian-She Wang Lu-Zhao Feng wei Liu Yi Zheng Sai-Nan Shu Min Lu Wan-Jun Luo Miao Liu Yu-Xia Cui Le-Ping Ye A-Dong Shen Gang Liu Li-wei Gao Li-Juan Xiong Yan Bai Li-Kai Lin zhuang wei Feng-Xia Xue Tian-You Wang Dong-Chi Zhao Jian-Bo Shao Daniel Kwok-keung Ng Gary Wing-kin Wong Zheng-Yan Zhao Xing-Wang Li Yong-Hong Yang Kun-Ling Shen Diagnosis and Treatment Center of Infectious Diseases Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Beijing Key Laboratory of Pediatric Respiratory Infection Diseases Key Laboratory of Major Diseases in ChildrenMinistry of EducationNational Clinical Research Center for Respiratory DiseasesResearch Unit of Critical Infection in ChildrenChinese Academy of Medical Sciences2019RU016Laboratory of Infection and VirologyBeijing Pediatric Research InstituteBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China Department of Pediatrics Renmin Hospital of Wuhan UniversityWuhan 430060China Department of Respiratory Wuhan Children's HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430016China Department of Pediatrics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Respiratory Shenzhen Children's HospitalShenzhen 518038China Department of Pediatric Respiratory Shengjing Hospital Affiliated to China Medical UniversityShenyang 110004China Department of Respiratory Beijing Children's HospitalCapital Medical UniversityNational Clinical Research Center for Respiratory DiseasesNational Center for Children's HealthBeijing 100045China Department of Neurology Wuhan Children's HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430016China Department of Respiratory Guangzhou Women and Children's Medical CenterGuangzhou 510623China Department of Infectious Diseases Shenzhen Children's HospitalShenzhen 518038China Department of Pediatrics Fujian Branch of Shanghai Children's Medical CenterFujian Children's HospitalFuzhou350005China Department of Clinical Immunology and Allergy Children's Hospital of Fudan UniversityNational Center for Children's HealthShanghai 201102China Department of Infectious Diseases Children's Hospital of Fudan UniversityNational Center for Children's Health.Shanghai

It has been more than 3 years since the novel coronavirus(SARS-CoV-2)pandemic raged globally.The coronavirus disease 2019(COVID-19)has greatly influenced human society.According to data from the World Health Organization(WHO),there were over 656 million confirmed cases of COVID-19 in the world as of January 1,2023,including over 6.6 million deaths[1].

关键词： prevention infection statement

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Differences in spring precipitation over southern China associated with multiyear La Ni?a events

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Acta Oceanologica Sinica 2024年第2期43卷 1-10页

作者： Guangliang Li Licheng Feng wei zhuang Fei Liu Ronghua Zhang Cuijuan Sui National Marine Environmental Forecasting Center Ministry of Natural ResourcesBeijing 100081China State Key Laboratory of Marine Environmental Science College of Ocean and Earth SciencesXiamen UniversityXiamen 361102China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519082China Key Laboratory of Tropical Atmosphere-Ocean System of Ministry of Education/School of Atmospheric Sciences Sun Yat-Sen UniversityZhuhai 519082China School of Marine Sciences Nanjing University of Information Science and TechnologyNanjing 210044China

Composite analyses were performed in this study to reveal the difference in spring precipitation over southern China during multiyear La Ni?a events during 1901 to 2015. It was found that there is significantly below-normal precipitation during the first boreal spring, but above-normal precipitation during the second year. The difference in spring precipitation over southern China is correlative to the variation in western North Pacific anomalous cyclone(WNPC), which can in turn be attributed to the different sea surface temperature anomaly(SSTA) over the Tropical Pacific. The remote forcing of negative SSTA in the equatorial central and eastern Pacific and the local air-sea interaction in the western North Pacific are the usual causes of WNPC formation and maintenance.SSTA in the first spring is stronger than those in the second spring. As a result, the intensity of WNPC in the first year is stronger, which is more likely to reduce the moisture in southern China by changing the moisture transport, leading to prolonged precipitation deficits over southern China. However, the tropical SSTA signals in the second year are too weak to induce the formation and maintenance of WNPC and the below-normal precipitation over southern China. Thus, the variation in tropical SSTA signals between two consecutive springs during multiyear La Ni?a events leads to obvious differences in the spatial pattern of precipitation anomaly in southern China by causing the different WNPC response.

关键词： multiyear La Nina precipitation anomaly anomalous western North Pacific cyclone southern China

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An Improved YOLOv7 tiny Algorithm for Vehicle and Pedestrian Detection with Occlusion in Autonomous Driving

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Chinese Journal of Electronics 2024年

作者： Jian SU Fang WANG wei zhuang Nanjing University of Information Science and Technology

Future transportation is advancing in the direction of intelligent transportation systems, where an essential part is vehicle and pedestrian detection. Due to the complex urban traffic environment, vehicles and pedestrians in road monitoring have different forms of occlusion problems, resulting in the missed detection of objects. We design an improved you only look once version 7(YOLOv7) tiny algorithm for vehicle and pedestrian detection under occlusion, with the following four main improvements. In order to locate the object more accurately, 1 × 1 convolution and identity connection are added to the 3 × 3 convolution, and convolution reparameterization is used to enhance the inference speed of the network model. In view of the complex road background and more interference, the coordinate attention was added to the connection part of backbone and neck to enhance the network's capacity to detect the object and lessen interference from other targets. At the same time, before being sent to the detection head, global attention mechanism is added to improve the accuracy of model detection by capturing three-dimensional features. Considering the issue of imbalanced training samples, we propose focal complete intersection over union(CIOU) loss instead of CIOU loss to become the bounding box regression loss, so that the regression process attention to high-quality anchor boxes. Experiments show that the improved YOLOv7 tiny algorithm achieves 82.2%map@0.5 in Pattern Analysis, Statistical Modelling and Computational Learning Visual Object Classes(PASCAL VOC) dataset, which is 2.8% higher than before the improvement. The performance of map@0.5:0.95 is 5.2% better than the previous improvement. The proposed improved algorithm can availably to detect partial occlusion objects.

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AOYOLO Algorithm Oriented Vehicle and Pedestrian Detection in Foggy Weather

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Chinese Journal of Electronics 2024年

作者： Jian SU Shiang MAO wei zhuang Nanjing University of Information Science and Technology

In the context of complex foggy environments, the acquired images often suffer from low visibility,high noise, and loss of detailed information. The direct application of general object detection methods fails to achieve satisfactory results. To address these issues, this paper proposes a foggy object detection method based on YOLOv8n,named AOYOLO. The all-in-one dehazing network(AOD-Net), a lightweight defogging network, is employed for data augmentation. Additionally, the ResCNet module is introduced in the backbone to better extract features from low-illumination images. The GACSP module is proposed in the neck to capture multi-scale features and effectively utilize them, thereby generating discriminative features with different scales. The detection head is improved using WiseI oU, which enhances the accuracy of object localization. Experimental evaluations are conducted on the publicly available datasets annotated realworld task-driven testing set(RTTS) and synthetic foggy KITTI dataset. The results demonstrate that the proposed AOYOLO algorithm outperforms the original YOLOv8n algorithm with an average mean average precision improvement of 3.3% and 4.6% on the RTTS and KITTI datasets, respectively. The AOYOLO method effectively enhances the performance of object detection in foggy scenes. Due to its improved performance and stronger robustness, this experimental model provides a new perspective for foggy object detection.

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Determinants of infant behavior and growth in breastfed late preterm and early term infants:a secondary data analysis

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World Journal of Pediatrics 2023年第10期19卷 983-991页

作者： Xinzhuo Zhang Jinyue Yu zhuang wei Mary Fewtrell Division of Medicine University College LondonLondonUK Population Policy and Practice Research and Teaching DepartmentUCL Great Ormond Street Institute of Child HealthUniversity College LondonLondonUK Department of Child Healthcare Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijingChina

Background Late preterm and early term infants are at increased risk of poor growth,behavioral problems,and developmental delays.This study aimed to investigate the impact of maternal and infant characteristics,feeding practices,and breastmilk composition on infant behavior following late preterm and early term delivery,and to evaluate the association between infant behavior and growth.Methods Data from 52 Chinese mothers and their late preterm/early term infants participating in the Breastfeed a Better Youngster study were used.Maternal and infant characteristics were collected using questionnaires at 1 week postpartum.Breastmilk macronutrient content was measured using a human milk analyzer,and infant behavior was assessed using a 3-day infant behavior diary at 8 weeks postpartum.Feeding practices were collected at both time points using questionnaires.Multivariate models were used to assess associations between potential predictors and infant behavior and between infant behavior and growth.Results Exclusive breastfeeding was associated with greater sleep duration(P=0.02)and shorter crying duration(P=0.01).Mothers with a vocational education reported greater distress duration(P=0.006).Greater colic duration was associated with higher maternal annual income(P=0.004).There was no significant association between infant behavior and growth(all P>0.05).Conclusions Exclusive breastfeeding might promote more favorable infant behaviors in late preterm/early term infants,while the development of infant distress behaviors was associated with some maternal characteristics(maternal education and annual income).However,due to the limitations of diary methods,determinants of infant behavior should ideally be assessed using more objective measures in larger samples.

关键词： Breastfeeding Growth and development Infant behavior Premature infant

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On the longitudinal shifts of the Agulhas retroflection point

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Acta Oceanologica Sinica 2024年第5期43卷 16-29页

作者： weiwei Zhang Xiaoyi Yang wei zhuang Xiaohai Yan State Key Laboratory of Marine Environmental Science College of Ocean and Earth SciencesXiamen UniversityXiamen 361002China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519082China Center for Remote Sensing College of EarthOcean and EnvironmentUniversity of DelawareNewarkDE 19716USA Joint Center for Remote Sensing University of Delaware-Xiamen UniversityNewarkDE 19716USA and Xiamen 361002China

The Agulhas system is the strongest western boundary current system in the Southern Hemisphere and plays an important role in modulating the Indian-to-Atlantic Ocean water exchange by the Agulhas leakage.It is difficult to measure in situ transport of the Agulhas leakage as well as the Agulhas retroflection position due to their intermittent nature.In this study,an innovative kinematic algorithm was designed and applied to the gridded altimeter observational data,to ascertain the longitudinal position of Agulhas retroflection,the stability of Agulhas jet stream,as well as its strength.The results show that the east-west shift of retroflection is related neither to the strength of Agulhas current nor to its stability.Further analysis uncovers the connection between the westward extension of Agulhas jet stream and an anomalous cyclonic circulation at its northern side,which is likely attributed to the local wind stress curl anomaly.To confirm the effect of local wind forcing on the east-west shift of retroflection,numerical sensitivity experiments were conducted.The results show that the local wind stress can induce a similar longitudinal shift of the retroflection as altimetry observations.Further statistical and case study indicates that whether an Agulhas ring can continuously migrate westward to the Atlantic Ocean or re-merge into the main flow depends on the retroflection position.Therefore,the westward retroflection may contribute to a stronger Agulhas leakage than the eastward retroflection.

关键词： Agulhas system Agulhas leakage retroflection position local wind stress curl

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Optimization of optical convolution kernel of optoelectronic hybrid convolution neural network

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Optoelectronics Letters 2022年第3期18卷 181-186页

作者： XU Xiaofeng ZHU Lianqing zhuang wei ZHANG Dongliang LU Lidan YUAN Pei School of Electro-Optical Engineering Changchun University of Science and TechnologyJilin 130022China Key Laboratory of the Ministry of Education for Optoelectronic Measurement Technology and Instrument Beijing Information Science and Technology UniversityBeijing 100192China Beijing Laboratory of Optical Fiber Sensing and System Beijing Information Science and Technology UniversityBeijing 100016China

To enhance the optical computation’s utilization efficiency, we develop an optimization method for optical convolution kernel in the optoelectronic hybrid convolution neural network(OHCNN). To comply with the actual calculation process, the convolution kernel is expanded from single-channel to two-channel, containing positive and negative weights. The Fashion-MNIST dataset is used to test the network architecture’s accuracy, and the accuracy is improved by 7.5% with the optimized optical convolution kernel. The energy efficiency ratio(EER) of two-channel network is 46.7% higher than that of the single-channel network, and it is 2.53 times of that of traditional electronic products.

关键词： convolution kernel weights

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Synergistic effects of three traditional herbs green tea,mulberry leaf and corn silk on glucose uptake level of L6 myoblasts and the hypoglycemic mechanism

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Traditional Medicine Research 2024年第7期9卷 1-12页

作者： Jing-Na Zhou Ming-Yue Li Ting-Ting Zhang Jing-Yang Lu Min Zhang Peng-wei zhuang Hai-Xia Chen Tianjin Key Laboratory for Modern Drug Delivery&High-Efficiency School of Pharmaceutical Science and TechnologyTianjin UniversityTianjin 300072China. School of Food Science and Bioengineering Tianjin Agricultural UniversityTianjin 300384China. State Key Laboratory of Nutrition and Safety Tianjin University of Science&TechnologyTianjin 300457China. Haihe Laboratory of Modern Chinese Medicine Chinese Materia Medica CollegeTianjin University of Traditional Chinese MedicineTianjin 301617China.

Background:Green tea,mulberry leaf and corn silk are traditional herbs used in the prevention and treatment of diabetes in China for a long time,but their synergistic hypoglycemic effects and mechanisms remain unclear.Methods:The effective components of green tea,mulberry leaf and corn silk were extracted and enriched.Mixture design of experiments was used to study the influences of different combinations on the cell viability and glucose uptake level of L6 myoblasts,so as to determine the optimal synergistic hypoglycemic combination.The possible hypoglycemic mechanism of the optimal synergistic combination was explored by cytotoxicity assay,glucose uptake assay,and western blot.Results:Three polyphenol enrichment fractions of the herbs,30%ethanol elution fraction of green tea(GT),50%ethanol elution fraction of mulberry leaf(ML)and 60%ethanol elution fraction of corn silk(CS)were obtained.The antioxidant activities of GT-30%,ML-50%and CS-60%were superior to those of crude extracts,and showed strong potential inα-amylase andα-glucosidase inhibition activities.The optimal synergistic combination of crude extracts G7(crude extract of green tea:crude extract of mulberry leaf:crude extract of corn silk=1:5:3),polyphenol enrichment fractions R3(GT-30%:ML-50%:CS-60%=1:7:1)and monomers X2(epigallocatechin gallate:morusin:formononetin=3:1:2)were selected,respectively.G7,R3,and X2 showed promoting effects on the cell viability and glucose uptake of L6 myoblasts within the detected concentration range.In addition,G7,R3,and X2 could increase the expression levels of p-PI3K/PI3K and p-Akt/Akt in L6 myoblasts,and promote the translocation of Glut4,but G7 and R3 showed more significant effects.Conclusion:The synergistic hypoglycemic effects of green tea,mulberry leaf and corn silk had the characteristics of multiple-components and multiple-targets with p-PI3K/PI3K,p-Akt/Akt and the translocation of Glut4 signal pathways involved.The three traditional herbs might have the potential to be combined used for the prevention and trea

关键词： green tea mulberry leaf corn silk synergistic effect type 2 diabetes mellitus mechanism

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一种基于5G应用的圆极化微带相控阵天线

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微波学报 2024年第1期40卷 13-17页

作者：李冯庄伟南京师范大学计算机与电子信息学院/人工智能学院南京210023 南京师范大学物理科学与技术学院南京210023

本文提出一款应用于5G频段,可实现方位面±40°波束扫描的圆极化微带相控阵天线。该相控阵天线单元是由矩形贴片、上下介质板、缝隙耦合馈电结构、金属反射板构成。利用切比雪夫综合法的一分八不等分功分器实现相控阵天线的馈电形式。... 详细信息

本文提出一款应用于5G频段,可实现方位面±40°波束扫描的圆极化微带相控阵天线。该相控阵天线单元是由矩形贴片、上下介质板、缝隙耦合馈电结构、金属反射板构成。利用切比雪夫综合法的一分八不等分功分器实现相控阵天线的馈电形式。测试结果表明,阵列天线的驻波比带宽为3.25 GHz~3.69 GHz,端口隔离度大于25 dB,扫描过程中增益最大为21 dB,增益衰落小于3 dB,最大扫描角处轴比为2.89 dB。该天线具有低剖面、高隔离度、高增益以及良好的波束扫描性能等优点。

关键词： 5G 微带相控阵低剖面波束扫描

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温度和湿度对P-CNT自感知混凝土压敏性的影响

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河海大学学报（自然科学版） 2024年第3期52卷 72-78页

作者：孙敏朱浩然庄伟苏州科技大学土木工程学院江苏苏州215009 中国建筑第五工程局一公司湖南长沙410004

为研究温度与湿度对自感知混凝土(SSC)感知性能的影响,通过低温等离子体改性处理技术对碳纳米管(CNT)进行官能团嫁接,使其在水性体系下获得较好的分散性,并将改性后的CNT(P-CNT)加入混凝土中制备P-CNT/SSC传感器,通过改变含水率与温度... 详细信息

为研究温度与湿度对自感知混凝土(SSC)感知性能的影响,通过低温等离子体改性处理技术对碳纳米管(CNT)进行官能团嫁接,使其在水性体系下获得较好的分散性,并将改性后的CNT(P-CNT)加入混凝土中制备P-CNT/SSC传感器,通过改变含水率与温度条件研究P-CNT/SSC传感器的极化效应与循环加载下的自感知性能。试验结果表明:过高或过低的含水率均不利于SSC的感知性能,其中变化最为明显的是饱水状态下的P-CNT/SSC传感器,其应力敏感系数下降89.8%,并且压敏曲线极不稳定;在变温试验中,P-CNT/SSC传感器的电阻率与温度之间呈现负相关性,高温和低温下的应力敏感系数相较于常温组试件,分别下降了约35.66%和44.53%,并且压敏曲线整体出现了上移或下滑的趋势;P-CNT/SSC传感器在工程应用中的最佳测试环境为常温、自然含水率。

关键词：自感知混凝土碳纳米管压敏性低温等离子体改性极化效应循环加载

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