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基于炮制前后质量一致性的清半夏炮制新工艺评价

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天然产物研究与开发 2024年第3期36卷 485-498页

作者：颜雨豪殷莉丽黎智蒋孟莲杨转珍万子玉赖月月李敏成都中医药大学药学院/现代中药产业学院省部共建西南特色中药资源国家重点实验室成都611137

为研究半夏与清半夏的质量传递关系,并评价新工艺蒸法所得炮制品与清半夏的质量一致性,本研究检测了生半夏及3种炮制品的浸出物、有机酸、多糖、核苷、蛋白质含量,使用主成分分析等方法比较3种炮制品的差异。结果表明,与生半夏相比,浸... 详细信息

为研究半夏与清半夏的质量传递关系,并评价新工艺蒸法所得炮制品与清半夏的质量一致性,本研究检测了生半夏及3种炮制品的浸出物、有机酸、多糖、核苷、蛋白质含量,使用主成分分析等方法比较3种炮制品的差异。结果表明,与生半夏相比,浸、煮制清半夏的浸出物减少,而蒸制品浸出物增加了264.76%;总酸、多糖含量均显著增加,其中蒸制品的增幅最大;核苷、蛋白质含量均大幅降低;综合分析方法均表明蒸制品与传统方法所得清半夏存在较大的质量差异。由此可知,浸、煮制清半夏质量一致性较好,而蒸法炮制品仍需对其加工工艺、药效做进一步研究。

关键词：半夏清半夏炮制工艺质量传递主成分分析一致性

锥齿轮综合检验机主轴相交度误差检测与补偿方法研究

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机电产品开发与创新 2024年第3期37卷 187-190页

作者：史鉴李金峰张敬彩韩瑞麒杨转玲雁栖湖基础制造技术研究院有限公司北京100044 中机生产力促进中心有限公司北京100044

随着航空等传动领域对锥齿轮传动振动性能及寿命可靠性需求的不断提升,对锥齿轮综合检验机的精度和功能要求进一步提高。轴线相交度是锥齿轮综合检验机的一项重要的精度指标,但现有的测量方法只能测量特定设备中轴线的相交度,不具有广... 详细信息

随着航空等传动领域对锥齿轮传动振动性能及寿命可靠性需求的不断提升,对锥齿轮综合检验机的精度和功能要求进一步提高。轴线相交度是锥齿轮综合检验机的一项重要的精度指标,但现有的测量方法只能测量特定设备中轴线的相交度,不具有广泛适用性。本文研究提出了一种新的检测方法,用于评估检验机主轴相交度误差。该方法利用高精度检棒延伸轴线在空间相交,简化了测量过程。结合检验机的结构特点,计算出相交度误差的补偿方法,根据不同锥齿轮副轴交角计算对应的补偿量。这种补偿方法提高了检验机的测量准确性。补偿完成后,通过球头检棒验证补偿结果,进一步确保测量的可靠性。

关键词：锥齿轮综合检验机相交度误差检测误差补偿

同方期刊数据库博看期刊评论

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超浅层顶管施工引起路基地层移动数值模拟

重庆建筑大学学报 2008年第5期30卷 58-62页

作者：杨转运重庆大学土木工程学院重庆400045 四川建筑职业技术学院四川德阳618000

覆盖土层薄的超浅层顶管穿越路基施工引起管道周围土体移动会对路面结构造成破坏。结合实际工程,运用有限元模拟超浅层顶管穿越路基引起的地层移动和现场地表变形监测,研究了管道摩擦力、注浆率、顶推力、路面交通荷载等因素对覆盖土层... 详细信息

覆盖土层薄的超浅层顶管穿越路基施工引起管道周围土体移动会对路面结构造成破坏。结合实际工程,运用有限元模拟超浅层顶管穿越路基引起的地层移动和现场地表变形监测,研究了管道摩擦力、注浆率、顶推力、路面交通荷载等因素对覆盖土层变形的影响。研究表明:地层移动是先隆起后沉降,覆盖土层下部的移动速度比表层的大;地表变形的有限元计算结果和现场实测数据基本吻合;超浅层顶管施工对浅埋覆盖路基土层移动,横断面地表沉降变形在工具管纵向通过2倍顶管外径后基本趋于稳定,横向地表沉降沿侧向分布近似为正态分布,主要影响范围在顶管轴线左右两侧各1.5倍顶管外径的范围内;变形要求严格的地面下进行超浅层顶管施工,可以通过有限元分析对周围环境影响程度的评价。

关键词：超浅层顶管地层移动三维有限元模拟

On entire solutions of some Fermat type differential-difference equations

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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 69-88页

作者： LONG Jian-ren QIN Da-zhuan School of Mathematical Sciences Guizhou Normal UniversityGuiyang 550025China

On one hand,we study the existence of transcendental entire solutions with finite order of the Fermat type difference *** the other hand,we also investigate the existence and growth of solutions of nonlinear different... 详细信息

关键词： entire solutions differential-difference equations existence finite order

基于HSI颜色模型的杂草与土壤背景分割方法研究

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河北农业大学学报 2011年第4期34卷 124-127页

作者：杨转廊坊市广播电视大学河北廊坊065000

针对杂草识别中如何将杂草与土壤背景分离问题,提出了利用HSI颜色模型中的H分量分割杂草和土壤背景的方法:该方法首先把RGB彩色空间转换到HSI彩色空间,然后根据色度分量(H)确定阈值将灰度图像转化为二值图像,并在此基础上进行适当腐蚀... 详细信息

针对杂草识别中如何将杂草与土壤背景分离问题,提出了利用HSI颜色模型中的H分量分割杂草和土壤背景的方法:该方法首先把RGB彩色空间转换到HSI彩色空间,然后根据色度分量(H)确定阈值将灰度图像转化为二值图像,并在此基础上进行适当腐蚀、膨胀,实现了杂草和土壤背景的准确分割。实验结果表明,该方法的准确率达到90%,验证了该方法的有效性。

关键词：杂草识别 HSI颜色空间图像分割

PC-SAFT理论对CO_2-甲醇体系相平衡的研究

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化工自动化及仪表 2010年第12期37卷 80-82页

作者：杨传宁夏电力科学研究院银川750002

主要结合统计缔合流体理论(PC-SAFT),采用已有的CO2与甲醇纯流体分子参数,同时利用CO2与甲醇纯流体分子参数回归二元交叉作用参数。以CO2、甲醇的纯流体分子参数及回归所得的二元交叉作用参数作为输入,来关联和预测CO2-甲醇二元体系相... 详细信息

主要结合统计缔合流体理论(PC-SAFT),采用已有的CO2与甲醇纯流体分子参数,同时利用CO2与甲醇纯流体分子参数回归二元交叉作用参数。以CO2、甲醇的纯流体分子参数及回归所得的二元交叉作用参数作为输入,来关联和预测CO2-甲醇二元体系相平衡性质。本文不仅对CO2-甲醇二元体系p-x和p-ρ相图的预测结果与实验数据进行了比较,而且分析了温度、压力和两相密度等因素对CO2-甲醇二元体系界面性质的影响。

关键词： PC-SAFT 二氧化碳甲醇相平衡

Lactobacillus plantarum AR113 attenuates liver injury in D-galactose-induced aging mice via the inhibition of oxidative stress and endoplasmic reticulum stress

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Food Science and Human Wellness 2024年第2期13卷 885-897页

作者： Yongjun Xia Yujie Gong Xiangna Lin Yijin yang Xin Song Guangqiang Wang Zhiqiang Xiong yangyang Qian zhuan Liao Hui Zhang Lianzhong Ai School of Health Science and Engineering Shanghai Engineering Research Center of Food MicrobiologyUniversity of Shanghai for Science and TechnologyShanghai 200093China College of Life Sciences Linyi UniversityLinyi 276000China Department of Gastroenterol. Digestive Endoscopy CenterChanghai HospitalShanghai 200082China

Probiotics could effectively eliminate excess reactive oxygen species(ROS)generated during aging or lipid metabolism disorders,but their mechanism is *** major purpose of this study was to investigate the mechanism of Lactiplantibacillus plantarun AR113 alleviating oxidative stress injury in the D-galactose induced aging *** result showed that pretreatment with *** AR113 significantly relieving H_(2)O_(2)induced cytotoxicity in HepG2 cells by maintain cell membrane integrity and increasing antioxidant enzyme *** D-galactose induced aging mice,*** AR113 could significantly attenuate liver damage and inflammatory infiltration by promoting endogenous glutathione(GSH)synthesis and activating the Nrf2/Keap1 signaling pathway in mice,and increasing the expression of regulated phaseⅡdetoxification enzymes and antioxidant *** analysis shown that gavage of *** AR113 could significantly reduce the expression of G protein-coupled receptor 78(GPR78)and C/EBP homologous protein(CHOP)proteins,and promote the restoration of endoplasmic reticulum(ER)homeostasis,thereby activating cell anti-apoptotic *** results were also confirmed in H_(2)O_(2)-treated HepG2 *** indicated that *** AR113 could inhibit D-galactose-induced liver injury through dual inhibition of ER stress and oxidative *** AR113 have good application potential in anti-aging and alleviating metabolic disorders.

关键词： Lactiplantibacillus plantarun AR113 HepG2 D-galactose Oxidative stress ER stress

Growth Factors and Supporting Cells of Nerve Conduits for Peripheral Nerve Regeneration

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Chinese Journal of Plastic and Reconstructive Surgery 2019年第4期1卷 46-54页

作者： yang XIANG Zhi-Wu CHEN Jun-Shui ZHENG zhuan yang Guang-Hao LIN Peng WEI Department of Plastic and reconstructive surgery Ningbo First HospitalNingbo CityZhejiang Province315010China Ningbo university Ningbo CityZhejiang Province315010China

Peripheral nerve injury is a common disease that endangers human *** is a variety of methods to repair peripheral nerve injury,the current"gold standard"approach is autograft,however it still faces many disadvantages.A new choice is the use of artificial nerve conduits,which are tubular structures and are designed to bridge nerve *** order to bridge longer nerve gaps and gain ideal nerve regeneration effects,multiple technologies have been developed to the design of nerve conduits,such as selecting sutible materials,supplementing growth factors,transplanting supporting cells and so *** review mainly introduce current progess in growth factors supplementation and supporting cells transplantation technology of nerve conduits.

关键词： peripheral nerve injury nerve conduits growth factors supporting cells

Correlation between postoperative chemotherapy regimen and survival in patients with resectable gastric adenocarcinoma accompanied with vascular cancer thrombus

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1618-1628页

作者： Ze-Feng yang zhuan-Xia Dong Chen-Jie Dai Li-Zheng Fu Hong-Mei Yu Yu-Sheng Wang Department of Health Statistics School of Public HealthShanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Shanxi Medical University Taiyuan 030001Shanxi ProvinceChina Shanxi Provincial Key Laboratory of Major Diseases Risk Assessment Taiyuan 030001Shanxi ProvinceChina MOE Key Laboratory of Coal Environmental Pathogenicity and Prevention Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Department of Oncology Digestive The First Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Department of Digestive Oncology Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer HospitalChinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina

BACKGROUND Patients with resectable gastric adenocarcinoma accompanied by vascular cancer thrombus(RGAVCT)have a poor prognosis,with a 5-year survival rate ranging from 18.42%-53.57%.These patients need a reasonable postoperative treatment plan to improve their *** To determine the most effective postoperative chemotherapy regimen for patients with *** We retrospectively collected the clinicopathological data of 530 patients who un-derwent radical resection for gastric cancer between January 2017 and January 2022 and who were pathologically diagnosed with gastric adenocarcinoma with a choroidal cancer ***-thermore,we identified the high-risk variables that can influence the prognosis of patients with RGAVCT by asse-ssing the clinical and pathological features of the patients who met the inclusion *** also assessed the significance of survival outcomes using Mantel-Cox univariate and multivariate *** subgroups of pa-tients with stages Ⅰ,Ⅱ,and Ⅲ disease who received single-,dual-,or triple-drug regimens following surgery were analyzed using SPSS 25.0 and the ggplot2 package in R *** In all,530 eligible individuals with RGAVCT were enrolled in this *** median overall survival(OS)of patients with RGAVCT was 24 months,and the survival rates were 80.2%,62.5%,and 42.3%at 12,24,and 59 months,*** complications,tumor size,T stage,and postoperative chemotherapy were identified as independent factors that influenced OS in patients with RGAVCT according to the Cox multivariate analysis model.A Kaplan-Meier analysis revealed that chemotherapy had no effect on OS of patients with stage Ⅰ or Ⅱ RGAVCT;however,chemotherapy did have an effect on OS of stage Ⅲ *** Ⅲ patients who were treated with chemotherapy consisting of dual-or triple-agent regimens had better survival than those treated with single-agent regimens,and no significant difference was observed in the survival of patients treat

关键词： Vascular cancer embolism Postoperative chemotherapy regimen Gastric adenocarcinoma Risk factors Survival