检索结果-南通市图书馆

Meta-analysis of capsule endoscopy in patients diagnosed or suspected with esophageal varices

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第10期15卷 1254-1258页

作者： Yi Lu Rui Gao zhuan liao Liang-Hao Hu Zhao-Shen Li Department of Gastroenterology Changhai Hospital SecondMilitary Medical University 168 Changhai Road Shanghai200433 China

AIM:To review the literature on capsule endoscopy(CE) for detecting esophageal varices using conventional esophagogas troduodenoscopy(EGD)as the standard. METHODS:A strict literature search of studies comparing the yield of CE and EGD in patients diagnosed or suspected as having esophageal varices was conducted by both computer search and manual *** were extracted to estimate the pooled diagnostic sensitivity and specificity. RESULTS:There were seven studies appropriate for meta-analysis in our study,involving 446 patients. The pooled sensitivity and specificity of CE for detecting esophageal varices were 85.8%and 80.5%, *** subgroup analysis,the pooled sensitivity and specificity were 82.7%and 54.8%in screened patients,and 87.3%and 84.7%in the screened/ patients under surveillance,respectively. CONCLUSION:CE appears to have acceptable sensitivity and specificity in detecting esophageal ***,data are insufficient to determine the accurate diagnostic value of CE in the screen/ surveillance of patients alone.

关键词： Meta-analysis Esophageal varices Esophageal capsule endoscopy Sensitivity Specificity

Fields of applications,diagnostic yields and findings of OMOM capsule endoscopy in 2400 Chinese patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2010年第21期16卷 2669-2676页

作者： liao, zhuan Gao, Rui Li, Feng Xu, Can Zhou, Yi Wang, Jin-Shan Li, Zhao-Shen Second Mil Med Univ Changhai Hosp Dept Gastroenterol Capsule Endoscopy Study Grp Shanghai 200433 Peoples R China Jianshan Sci & Technol Grp Co Ltd Chongqing 401120 Peoples R China

AIM:To retrospectively analyze the fields of application,diagnostic yields and findings of OMOM capsule endoscopy in Chinese ***:A database including 2400 Chinese patients who received OMOM capsule endoscopy in 27 endoscopy centers in China was retrieved from the Jianshan Science and Technology *** capsule endoscopy *** patient's age,gender,fields of application,the potentially relevant findings,pyloric transit time(PTT),small bowel transit time(SBTT),and complete small-bowel examination rate(CSER) were recorded and ***:Two thousand four hundred patients aged 9-91 years(mean,49 years),of whom 1510 were males(62.9%),underwent 2400 OMOM capsule endoscopy *** thousand two hundred and thirty two(51.3%) were referred with obscure gastrointestinal bleeding(OGIB),642(26.8%) with abdominal pain,and 223(9.3%) with chronic *** overall diagnostic yield was 47.7%(1144/2400).The diagnostic yield of OMOM capsule endoscopy in OGIB subgroup was much higher than in the non-OGIB subgroup(62.4% vs 32.1%,P<0.001).The most common findings of the small bowel in Chinese patients with OGIB were arteriovenous malformation(28.1%) and tumors(18.9%).There was no significant difference in the diagnostic yield between the male and female patients with ***,the diagnostic yield in patients aged more than 60 was higher than in patients aged less than 60(69.8% vs 58.9%,P<0.001).The median PTT was 41 min(range:1-544 min) and the mean SBTT was 247.2 ± 88.9 *** overall CSER was 86.8%.CONCLUSION:The OMOM capsule endoscopy is a valuable tool for small bowel evaluation with good overall diagnostic yield and CSER.

关键词： OMOM capsule endoscopy Obscure gastrointestinal bleeding Small bowel

Lactobacillus plantarum AR495 improves stress-induced irritable bowel syndrome in rats by targeting gut microbiota and Mast cell-PAR2-TRPV1 signaling pathway

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年第2期13卷 698-708页

作者： Hongyun Zhang Guangqiang Wang Zhiqiang Xiong zhuan liao Yangyan Qian Xin Song Li Sui Lianzhong Ai Yongjun Xia Shanghai Engineering Research Center of Food Microbiology School of Health Science and EngineeringUniversity of Shanghai for Science and TechnologyShanghai 200093China Department of Gastroenterol Digestive Endoscopy CenterShanghai HospitalShanghai 200093China

Probiotics have great potential in regulating intestinal *** this study,the effects of Lactobacillus plantarum AR495 on the visceral sensitivity and gut microbiota of irritable bowel syndrome(IBS)rats were *** results showed that tryptase released after mast cell activation and degranulation plays a key role in visceral pain,and *** AR495 reduced the stimulation of colonic mast cells and the expression of protease-activated receptor 2(PAR2)and TRPV1 in dorsal root *** further showed that supplementation with *** AR495 increased the level of short-chain fatty acids(SCFAs)and enhanced the barrier function of the *** addition,the microbiota analysis of the colon indicated that *** AR495 promoted the proliferation of Bifidobacterium and inhibited the proliferation of Lachnospiraceae,which alleviated the imbalance of the intestinal microbiota caused by IBS to a certain *** total,*** AR495 might reduce visceral sensitivity through the Mast cell-PAR2-TRPV1 signaling pathway by maintaining the homeostasis of the intestinal barrier.

关键词： Lactobacillus plantarum Irritable bowel syndrome Visceral sensitivity Dorsal root ganglia Tryptase Microbiota

Wireless esophageal pH capsule for patients with gastroesophageal reflux disease: A multicenter clinical study

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第40期20卷 14865-14874页

作者： Xiao-Jun Yang Tian Gan Lei Wang zhuan liao Xiao-Hong Tao Wei Shen Xiao-Yan Zhao Department of Gastroenterology Xinqiao Hospital Third Military Medical University Department of Gastroenterology Changhai Hospital Second Military Medical University Departmentof Gastroenterology First Affiliated Hospital of Chongqing Medical University Department of Gastroenterology Second Affiliated Hospital of Chongqing Medical University

AIM: To investigate the feasibility and safety of pH capsule to monitor pH in patients with gastroesophageal reflux disease (GERD).

关键词： Wireless pH capsule Feasibility Safety Conventional catheter Gastroesophageal reflux disease

Lactobacillus plantarum AR113 attenuates liver injury in D-galactose-induced aging mice via the inhibition of oxidative stress and endoplasmic reticulum stress

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年第2期13卷 885-897页

作者： Yongjun Xia Yujie Gong Xiangna Lin Yijin Yang Xin Song Guangqiang Wang Zhiqiang Xiong Yangyang Qian zhuan liao Hui Zhang Lianzhong Ai School of Health Science and Engineering Shanghai Engineering Research Center of Food MicrobiologyUniversity of Shanghai for Science and TechnologyShanghai 200093China College of Life Sciences Linyi UniversityLinyi 276000China Department of Gastroenterol. Digestive Endoscopy CenterChanghai HospitalShanghai 200082China

Probiotics could effectively eliminate excess reactive oxygen species(ROS)generated during aging or lipid metabolism disorders,but their mechanism is *** major purpose of this study was to investigate the mechanism of Lactiplantibacillus plantarun AR113 alleviating oxidative stress injury in the D-galactose induced aging *** result showed that pretreatment with *** AR113 significantly relieving H_(2)O_(2)induced cytotoxicity in HepG2 cells by maintain cell membrane integrity and increasing antioxidant enzyme *** D-galactose induced aging mice,*** AR113 could significantly attenuate liver damage and inflammatory infiltration by promoting endogenous glutathione(GSH)synthesis and activating the Nrf2/Keap1 signaling pathway in mice,and increasing the expression of regulated phaseⅡdetoxification enzymes and antioxidant *** analysis shown that gavage of *** AR113 could significantly reduce the expression of G protein-coupled receptor 78(GPR78)and C/EBP homologous protein(CHOP)proteins,and promote the restoration of endoplasmic reticulum(ER)homeostasis,thereby activating cell anti-apoptotic *** results were also confirmed in H_(2)O_(2)-treated HepG2 *** indicated that *** AR113 could inhibit D-galactose-induced liver injury through dual inhibition of ER stress and oxidative *** AR113 have good application potential in anti-aging and alleviating metabolic disorders.

关键词： Lactiplantibacillus plantarun AR113 HepG2 D-galactose Oxidative stress ER stress

Study on chronic pancreatitis and pancreatic cancer using MRS and pancreatic juice samples

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2011年第16期17卷 2126-2130页

作者： Jian Wang Chao Ma zhuan liao Bing Tian Jian-Ping Lu Department of Radiology Changhai Hospital The Second Military Medical University Shanghai 200433 China Department of Gastroenterology Changhai HospitalThe Second Military Medical University Shanghai 200433 China

AIM:To investigate the markers of pancreatic diseases and provide basic data and experimental methods for the diagnosis of pancreatic ***:There were 15 patients in the present study,among whom 10 had pancreatic cancer and 5,chronic *** all patients,pancreatic cancer or chronic pancreatitis was located on the head of the ***-thology da-ta-of a-ll p-a-tients wa-s confirmed by biopsy and *** the 10 patients with pancreatic cancer,3 people had a medical history of longterm alcohol *** 5 patients with chronic pancreatitis,4 men suffered from alcoholic chronic *** juice samples were obtained from patients by endoscopic retrograde *** resonance spectroscopyn was performed on an 11.7-T scanner (Bruker DRX-500) using Call-Purcell-Meiboom-Gill pulse *** parameters were as follows:spectral width,15 KHz;time domain,64 K;number of scans,512;and acquisition time,2.128 ***:The main component of pancreatic juice included leucine,iso-leucine,valine,lactate,alanine,acetate,aspartate,lysine,glycine,threonine,tyrosine,histidine,tryptophan,and *** performing 1D 1H and 2D total correlation spectroscopy,we found a triplet peak at the chemical shift of 1.19 ppm,which only appeared in the spectra of pancreatic juice obtained from patients with alcoholic chronic *** triplet peak was considered the resonance of the methyl of ethoxy group,which may be associated with the metabolism of alcohol in the ***:The triplet peak,at the chemical shift of 1.19 ppm is likely to be the characteristic metabolite of alcoholic chronic pancreatitis.

关键词： Pancreatic juice Pancreatic cancer Chronic pancreatitis Magnetic resonance spectroscopy Magnetic resonance imaging

Capsule endoscopy in portal hypertension and varices

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Portal Hypertension & Cirrhosis 2024年第3期3卷 171-172页

作者： Jun Pan Zhaoshen Li zhuan liao Department of Gastroenterology National Clinical Research Center for Digestive DiseasesNational Key Laboratory of Immunity and InflammationShanghai Key Laboratory of Nautical Medicine and Translation of Drugs and Medical DevicesChanghai HospitalNaval Medical UniversityShanghaiChina

1|CAPSULE ENDOSCOPY VERSUS ESOPHAGOGASTRODUODENOSCOPY(EGD)FOR DIAGNOSING GASTROESOPHAGEAL VARICES(GEVs):CENTERS *** is the gold standard for diagnosing GEVs in patients with portal hypertension,but its invasiveness limits patients'*** the nature of noninvasiveness and direct visualization,capsule endoscopy has the potential to be an alternative to EGD for diagnosing varices.

关键词： endoscopy hypertension capsule

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

胶囊内镜廿年之发展:弱冠之年,而立之心

中华内科杂志 2020年第2期59卷 89-94页

作者：廖专李兆申海军军医大学长海医院消化内科国家消化系统疾病临床医学研究中心上海200433

自1999年人类第1次吞下胶囊内镜开始,胶囊内镜已走过了临床应用的20个年头。20年来,从问世到成为小肠疾病一线检查方式,从技术进步到适应证拓展,从小肠到全消化道,从诊断到治疗初探,从技术应用到并发症预防,胶囊内镜为小肠疾病乃至全消... 详细信息

自1999年人类第1次吞下胶囊内镜开始,胶囊内镜已走过了临床应用的20个年头。20年来,从问世到成为小肠疾病一线检查方式,从技术进步到适应证拓展,从小肠到全消化道,从诊断到治疗初探,从技术应用到并发症预防,胶囊内镜为小肠疾病乃至全消化道疾病的诊疗模式带来了革命性变化。谨以此文回顾过去20年胶囊内镜的发展,并展望其将对消化系统疾病诊治带来的巨大影响。

关键词：胶囊内镜 20年发展

A comprehensive review of recent advances in chronic pancreatitis

在线全文

学校读者我要写书评

暂无评论

Journal of Pancreatology 2024年第1期7卷 45-52页

作者： Sheng-Han Mao Wen-Bin Zou Xiao-Tong Mao Zhao-Shen Li zhuan liao Department of Gastroenterology Changhai HospitalThe Naval Medical UniversityShanghaiChina Shanghai Institute of Pancreatic Diseases ShanghaiChina

Chronic pancreatitis(CP)is a multifaceted disorder influenced by environmental and genetic factors,with smoking and alcohol consumption being major *** developments encompass the advent of innovative transgenic models and the identification of susceptibility genes,shedding light on the genetic aspect of *** pathogenesis of this disease involves a complex interplay of pancreatic acinar cell dysfunction,inflammatory reactions,and *** research delves into understanding these molecular ***,a pivotal symptom of CP,has been increasingly studied to develop effective therapeutic *** advancements,including endoscopic ultrasound,radiomics,and blood-based markers,have shown potential in enhancing early CP ***,recent clinical trials have optimized treatment approaches,such as pancreatic stone fragmentation,stent placement,and decision-making between endoscopic and surgical *** therapies,including chemical pancreatectomy and gene therapy,present promising opportunities for improved CP management.

关键词： Chronic pancreatitis Diagnosis Endoscopy Etiology Mechanism Surgery