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Expert consensus on irrigation and intracanal medication in root canal therapy

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International Journal of Oral Science 2024年第1期16卷 26-35页

作者： Xiaoying Zou Xin Zheng Yuhong Liang Chengfei Zhang Bing Fan Jingping Liang Junqi Ling zhuan bian Qing Yu Benxiang Hou Zhi Chen Xi Wei Lihong Qiu Wenxia Chen Wenxi He Xin Xu Liuyan Meng Chen Zhang Liming Chen Shuli Deng Yayan Lei Xiaoli Xie Xiaoyan Wang Jinhua Yu Jin Zhao Song Shen Xuedong Zhou Lin Yue Department of Cariology and Endodontology Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental MaterialsBeijingChina Center of Stomatology Peking University HospitalBeijingChina State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&West China Hospital of Stomatology Sichuan UniversityChengduChina Department of Emergency Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental MaterialsBeijingChina Restorative Dental Sciences EndodonticsFaculty of DentistryThe University of Hong KongPok Fu LamHong Kong SARChina State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration Key Laboratory of Oral Biomedicine Ministry of EducationHubei Key Laboratory of StomatologySchool&Hospital of StomatologyWuhan UniversityWuhanChina Department of Endodontics Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineCollege of StomatologyShanghai Jiao Tong UniversityNational Clinical Research Center for Oral DiseasesNational Center for StomatologyShanghai Key Laboratory of StomatologyShanghaiChina Department of Operative Dentistry and Endodontics Hospital of StomatologyGuanghua School of StomatologySun Yat-Sen University&Guangdong Provincial Key Laboratory of StomatologyGuangzhouChina State Key Laboratory of Oral&Maxillofacial Reconstruction and R

Chemical cleaning and disinfection are crucial steps for eliminating infection in root canal treatment. However, irrigant selection or irrigation procedures are far from clear. The vapor lock effect in the apical region has yet to be solved, impeding irrigation efficacy and resulting in residual infections and compromised treatment outcomes.

关键词： treatment irrigation Expert

Expert consensus on difficulty assessment of endodontic therapy

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International Journal of Oral Science 2024年第1期16卷 15-25页

作者： Dingming Huang Xiaoyan Wang Jingping Liang Junqi Ling zhuan bian Qing Yu Benxiang Hou Xinmei Chen Jiyao Li Ling Ye Lei Cheng Xin Xu Tao Hu Hongkun Wu Bin Guo Qin Su Zhi Chen Lihong Qiu Wenxia Chen Xi Wei Zhengwei Huang Jinhua Yu Zhengmei Lin Qi Zhang Deqin Yang Jin Zhao Shuang Pan Jian Yang Jiayuan Wu Yihuai Pan Xiaoli Xie Shuli Deng Xiaojing Huang Lan Zhang Lin Yue Xuedong Zhou State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Operative Dentistry and Endodontics West China Hospital of StomatologySichuan UniversityChengduChina Department of Cariology and Endodontology Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental MaterialsBeijingChina Department of Endodontics Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineCollege of StomatologyShanghai Jiao Tong UniversityNational Clinical Research Center for Oral DiseasesNational Center for StomatologyShanghai Key Laboratory of StomatologyShanghaiChina Department of Operative Dentistry and Endodontics Hospital of StomatologyGuanghuaSchool of StomatologySun Yat-Sen University&Guangdong Provincial Key Laboratory of StomatologyGuangzhouChina The State Key Laboratory Breeding Base of Basic Science of Stomatology(Hubei-MOST)&Key Laboratory of Oral Biomedicine Ministry of Education School and Hospital of StomatologyWuhan UniversityWuhanChina Department of Operative Dentistry&Endodontics School of StomatologyThe Fourth Military Medical UniversityXi’anChina Department of Endodontics Beijing Stomatological HospitalSchool of StomatologyCapital Medical UniversityBeijingChina State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Preventive Dentistry West China Hospital of StomatologySichuan UniversityChengduChina State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Geriatric dentistry West China Hospital of Stomatology

Endodontic diseases are a kind of chronic infectious oral disease. Common endodontic treatment concepts are based on the removal of inflamed or necrotic pulp tissue and the replacement by gutta-percha. However, it is very essential for endodontic treatment to debride the root canal system and prevent the root canal system from bacterial reinfection after root canal therapy(RCT). Recent research, encompassing bacterial etiology and advanced imaging techniques, contributes to our understanding of the root canal system’s anatomy intricacies and the technique sensitivity of RCT. Success in RCT hinges on factors like patients, infection severity, root canal anatomy, and treatment techniques. Therefore, improving disease management is a key issue to combat endodontic diseases and cure periapical lesions. The clinical difficulty assessment system of RCT is established based on patient conditions, tooth conditions, root canal configuration, and root canal needing retreatment, and emphasizes pre-treatment risk assessment for optimal outcomes. The findings suggest that the presence of risk factors may correlate with the challenge of achieving the high standard required for RCT. These insights contribute not only to improve education but also aid practitioners in treatment planning and referral decision-making within the field of endodontics.

关键词： anatomy difficulty treatment

Incremental cost analysis model of distribution network based on economic dispatch of distributed new-energy storage system

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CLEAN ENERGY 2024年第2期8卷 89-103页

作者： Zhou, zhuan bian, Jiayu Yu, Zhiyong State Grid Xinjiang Elect Power Co Ltd Urumqi Xinjiang Peoples R China

With the implementation of China's carbon-peaking and carbon-neutrality strategy, new energy will achieve leapfrog growth. Due to the good economics of distributed new-energy generation, it can not only save users' own investment, but also help to achieve local consumption of new energy. However, it will also bring about a series of incremental costs to the power grid. This paper first enumerates the concept, development status and scheduling mode of a distributed new-energy storage system. Based on the above, it establishes a new-energy power generation model and an energy storage system charging and discharging model, and proposes a global optimization scheduling model for a distributed new-energy storage system, considering the time-of-use electricity price and taking the lowest total operating cost of the distributed new-energy power generation system as the objective function. Finally, it proposes a distribution network incremental cost analysis model based on the penetration of distributed new energy. The calculation results show that the incremental cost of grid-connected distributed new energy is 1.0849, 1.2585 and 1.3473 yuan/kWh, respectively, which indicates that the global dispatching model can optimize the power consumption structure of a distributed power generation system, and has the function of peak shaving and valley filling, but the incremental cost of the distribution network will also increase. A new-energy power generation model and an energy storage system charging and discharging model use a global optimization scheduling method, considering the time-of-use electricity price and taking the lowest total operating cost as the objective function. The results show the incremental cost of grid-connected distributed new energy. Graphical Abstract

关键词： distributed new energy electrochemical energy storage economic dispatch distribution network cost time-sharing price

口腔规培生的口腔美学修复临床实践能力现状调查及影响因素分析

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口腔颌面修复学杂志 2024年第2期25卷 131-135页

作者：夏彦琳石洪黔肖薇薇赵熠黄翠边专梁珊珊口颌系统重建与再生全国重点实验室口腔生物医学教育部重点实验室口腔医学湖北省重点实验室武汉大学口腔医(学)院武汉430079

目的:研究口腔规培生的口腔美学修复临床实践能力现状并探索其相关影响因素。方法:选取2020年1月于武汉大学口腔医院口腔住院医师规范化培训基地在培的263名规培生为研究对象,采用问卷星对其基本特征及口腔美学修复临床实践能力进行调... 详细信息

目的:研究口腔规培生的口腔美学修复临床实践能力现状并探索其相关影响因素。方法:选取2020年1月于武汉大学口腔医院口腔住院医师规范化培训基地在培的263名规培生为研究对象,采用问卷星对其基本特征及口腔美学修复临床实践能力进行调研。采用χ2检验和多因素logistic回归模型进行数据分析。结果:30%以上的规培生已具备良好的口腔美学修复临床实践能力。超过57%的规培生已具备以下能力:使用数码设备记录影像资料、制作研究模型与诊断蜡型、进行医患沟通和制作临时修复体;具备数字化美学分析与设计等能力的规培生比例相对较低(<50%)。2017级(规培三年级)规培生更具备医技沟通、使用辅助方法监测牙体预备、制作临时修复体、采用牙周手术改善软组织美学、定期跟踪随访修复体使用情况以及患者口腔健康情况等口腔美学修复实践能力。口腔修复专业规培生更具备数字化分析与设计、制作研究模型与诊断蜡型、医患沟通、医技沟通、使用辅助方法监测牙体预备、采用牙周手术改善软组织美学、关注修复体对发音的影响、定期跟踪随访修复体使用情况以及患者口腔健康情况的能力。结论:大部分口腔规培生已具备一定的口腔美学修复临床实践能力,规培生的年级和专业是影响其口腔美学修复临床实践能力的相关因素。

关键词：住院医师规范化培训口腔美学修复临床实践

Immunolocalization of secretion complex in Streptococcus mutans

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Journal of Microbiology and Immunology 2007年第1期5卷 13-16页

作者： PING HU zhuan bian MING WEN FAN MIN NIE Key Laboratory for Oral Biomedical Engineering of Ministry of Education School and Hospital of Stomatology Wuhan University P. R. China

Each secretion （See） machinery minimally consists of three integral inner membrane pro- teins SecYEG. In order to know the distribution pattern of the Sec complex in Streptococcus mutans, we explored the subcellular localization of SecY. The anti-secY antibody was examined on Western blots to evaluate specificity. An indirect post-embedding immunogold method was used to determine the subcellular localization of the SecY in the cytoplasmic membrane of the Streptococcus mutans GS-5. lmmunoblotting experiments showed that the anti-seeY antibody specifically recognized a single band of about 47.8 kDa. Immunogold electron microscopy image of section with anti-secY antibody revealed a single intense focus of gold particles at a discrete location on the cytoplasmic membrane of the Streptococcus mutans GS-5. SecY clustered to an asymmetric microdomain, which indicated for the first time that See complex presented a unisite on the cytoplasmic membrane of Streptococcus mutans.

关键词： Streptococcus mutans Secretion complex SecY

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生物节律在牙体硬组织发育中的作用

中华口腔医学杂志 2023年第1期58卷 11-16页

作者：宋亚玲边专武汉大学口腔医学院特诊科武汉430079 武汉大学口腔医学院牙体牙髓科武汉430079

生物节律受生物钟调控, 是机体通过内源性生物钟对外界循环刺激产生反应而形成。生物节律紊乱与多种疾病的发生风险密切相关, 对口腔健康的影响也不容忽视。探究生物节律与牙体硬组织发育的关系及其分子机制, 有助于深刻理解牙体硬组织... 详细信息

生物节律受生物钟调控, 是机体通过内源性生物钟对外界循环刺激产生反应而形成。生物节律紊乱与多种疾病的发生风险密切相关, 对口腔健康的影响也不容忽视。探究生物节律与牙体硬组织发育的关系及其分子机制, 有助于深刻理解牙体硬组织发育缺陷性疾病的病因, 为牙体硬组织发育异常相关疾病的防治提供理论依据。本文在总结当前研究进展的基础上, 重点阐述生物节律参与牙体硬组织发育和形成的过程, 节律紊乱可影响牙釉质、牙本质形成, 并分析生物节律通过生物钟基因调控牙体硬组织发育的相关机制, 以期为牙发育异常疾病防治提供指导。

关键词：生物钟生物节律生物钟基因牙釉质发育牙本质发育

Incidence and Related Factors Associated with Postpreparation Pain after Intracanal Procedures in a Dental Teaching Hospital

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口腔医学研究 2008年第2期24卷 221-223页

作者： Yue Cheng Gary Shun - Pan Cheung zhuan bian Bin Peng School of Stomatology Wuhan University Wuhan 430079 Faculty of Dentistry The University of Hong Kong HKSAR China

目的:了解根管预备后疼痛发生率,并对一些可能与疼痛发生有关的因素进行分析。方法:选取2001年7月至2002年2月间武汉大学口腔医院牙体牙髓科完成的非一次法根管治疗纪录表,将相关信息输入计算机后作Chi-square test和logistic回归分析... 详细信息

目的:了解根管预备后疼痛发生率,并对一些可能与疼痛发生有关的因素进行分析。方法:选取2001年7月至2002年2月间武汉大学口腔医院牙体牙髓科完成的非一次法根管治疗纪录表,将相关信息输入计算机后作Chi-square test和logistic回归分析。结果:根管预备后疼痛发生率为11.5%。单因素分析和logistic回归发现身体状况、年龄、牙位于上颌或下颌、术前有无叩痛及牙髓活力为影响疼痛发生率的主要因素。结论:根管预备术后疼痛发生率较低;根管预备术后疼痛发生率受多种因素影响。

关键词：根管治疗疼痛

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基因突变与牙体硬组织发育异常

中华口腔医学杂志 2020年第5期55卷 316-322页

作者：宋亚玲边专武汉大学口腔医学院特诊科 430079 武汉大学口腔医学院牙体牙髓科 430079

牙体硬组织发育异常是非龋性疾病的重要内容,主要包括釉质发育不全和牙本质发育异常。这些疾病如果得不到及时有效的干预和治疗,往往会造成牙体组织敏感、缺损,甚至牙缺失,影响咀嚼功能和面部美观。目前很多口腔医师对此类疾病认识不足... 详细信息

牙体硬组织发育异常是非龋性疾病的重要内容,主要包括釉质发育不全和牙本质发育异常。这些疾病如果得不到及时有效的干预和治疗,往往会造成牙体组织敏感、缺损,甚至牙缺失,影响咀嚼功能和面部美观。目前很多口腔医师对此类疾病认识不足,亟需全面关注和重视此类疾病和患病人群。本文在总结目前研究进展的基础上,重点对此类疾病的临床分类、疾病表型及突变基因和致病机制等进行阐述和分析,以期为广大口腔医师和患病人群提供帮助。

关键词：牙釉质发育不全牙本质发育不全牙本质发育不良基因突变

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认识Ⅱ型牙本质发育不良

中华口腔医学杂志 2023年第8期58卷 766-771页

作者：宋亚玲边专武汉大学口腔医(学)院、口颌系统重建与再生全国重点实验室、口腔生物医学教育部重点实验室、口腔医学湖北省重点实验室武汉430079

Ⅱ型牙本质发育不良是遗传性牙本质发育异常的一个亚型,致病基因为牙本质涎磷蛋白基因,其突变导致牙齿正常发育过程受到影响。病变可累及乳牙列和恒牙列,主要表现为牙齿变色、磨耗,甚至继发咬合关系异常,如未及时治疗将显著影响患者的... 详细信息

Ⅱ型牙本质发育不良是遗传性牙本质发育异常的一个亚型,致病基因为牙本质涎磷蛋白基因,其突变导致牙齿正常发育过程受到影响。病变可累及乳牙列和恒牙列,主要表现为牙齿变色、磨耗,甚至继发咬合关系异常,如未及时治疗将显著影响患者的身心健康。该疾病在人群中患病率低,表型隐匿,临床诊断困难。本文主要对Ⅱ型牙本质发育不良的临床和影像学特征、诊断、鉴别诊断及治疗等方面进行阐述,以期提高临床医师对Ⅱ型牙本质发育不良的全面认识。

关键词：牙本质发育不全牙本质发育不良牙列,乳牙列,恒牙列,混合临床表型