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A reduced combustion mechanism of ammonia/diesel optimized with multi-objective genetic algorithm

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Defence Technology（防务技术） 2024年第4期34卷 187-200页

作者： Wanchen Sun Shaodian lin Hao Zhang Liang Guo Wenpeng Zeng Genan zhu Mengqi Jiang State Key Laboratory of Automotive Simulation and Control Jilin UniversityChangchun 130025China

For the deep understanding on combustion of ammonia/diesel,this study develops a reduced mechanism of ammonia/diesel with 227 species and 937 *** sub-mechanism on ammonia/interactions of N-based and C-based species(N—C)/NOx is optimized using the Non-dominated Sorting Genetic Algorithm II(NSGA-II)with 200 *** optimized mechanism(named as 937b)is validated against combustion characteristics of ammonia/methane(which is used to examine the accuracy of N—C interactions)and ammonia/diesel *** ignition delay times(IDTs),the laminar flame speeds and most of key intermediate species during the combustion of ammonia/methane blends can be accurately simulated by 937b under a wide range of *** for ammonia/diesel blends with various diesel energy fractions,reasonable predictions on the IDTs under pressures from 1.0 MPa to5.0 MPa as well as the laminar flame speeds are also achieved by *** particular,with regard to the IDT simulations of ammonia/diesel blends,937b makes progress in both aspects of overall accuracy and computational efficiency,compared to a detailed ammonia/diesel *** kinetic analysis reveals that the reaction pathway of ammonia during the combustion of ammonia/diesel blend mainly differs in the tendencies of oxygen additions to NH_2 and NH with different equivalence ratios.

关键词： Ammonia Diesel Combustion Kinetic mechanism Multi-objective optimization

Tipping Point Detection Using Reservoir Computing

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Research 2024年第1期2023卷 779-790页

作者： Xin Li Qunxi zhu Chengli Zhao Xuzhe Qian Xue Zhang Xiaojun Duan Wei lin College of Science National University of Defense TechnologyChangshaHunan 410073China Research Institute of Intelligent Complex Systems and MOE Frontiers Center for Brain Science Fudan UniversityShanghai 200433China Shanghai Artificial Intelligence Laboratory Shanghai 200232China School of Mathematical Sciences SCMSSCAMand CCSBFudan UniversityShanghai 200433China

Detection in high fidelity of tipping points,the emergence of which is often induced by invisible changes in internal structures or/and external interferences,is paramountly beneficial to understanding and predicting complex dynamical systems(CDSs).Detection approaches,which have been fruitfully developed from several perspectives(e.g.,statistics,dynamics,and machine learning),have their own advantages but still encounter difficulties in the face of high-dimensional,fluctuating ***,using the reservoir computing(RC),a recently notable,resource-conserving machine learning method for reconstructing and predicting CDSs,we articulate a model-free framework to accomplish the detection only using the time series observationally recorded from the underlying unknown CDSs.

关键词： computing record ping

Delineation of urban growth boundary based on FLUS model under the perspective of land use evaluation in hilly mountainous areas

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Journal of Mountain Science 2024年第5期21卷 1647-1662页

作者： ZHANG Yunping lin Jianping HUANG Yimin CHEN Zebin zhu Chenhui YUAN Hao School of Geography and Environmental Engineering Gannan Normal UniversityGanzhou 341000China Key Laboratory of Low Carbon Recycling Technology for Municipal Solid Waste in Jiangxi Province Ganzhou 341000China

With rapid economic development,the size of urban land in China is expanding *** Urban Growth Boundary(UGB)is an expandable spatial boundary for urban construction in a certain period in order to control the urban *** delineation of UGB can inhibit the disorderly spread of urban space and guide the normal development of the *** is of practical significance for the construction of green urban *** study utilizes GIS technology to establish a land construction suitability evaluation system for Nankang city,which is experiencing rapid urban expansion,and outlines the preliminary UGB under the future land use simulation(FLUS)*** the same time,considering the coupled coordination of"Production-Living-Ecological Space",and based on the suitability evaluation,we revised the preliminary UGB by combining the advantages of the patch-generating land use simulation(PLUS)model and the convex hull model to delineate the final *** results show that:1)the comprehensive score of the evaluation of the suitability of the construction of land from high to low shows the distribution of the center of the city to the surrounding circle type spread,the center of the city has the highest suitability *** results of convex hull model show that the urban expansion type of Nankang is *** the future,the urban expansion will mainly occur in the northern part of the *** PLUS model predicts an increase of 3359.97 hm^(2)of construction land in Nankang by 2035,of which 2022.97 hm^(2)is urban construction land.2)The FLUS model has a prediction accuracy of 86.3%and delineates a preliminary UGB area of 9215.07 hm^(2).3)We used the results of the construction suitability evaluation,PLUS model simulation results,and convex hull model predictions to revise the originally delineated *** final delineated UGB area is 8895.67 hm^(2)and it is capable of meeting the future development of the study *** results of the delineation can promote

关键词： Urban sprawl FLUS model Spatial correction Urban growth boundary Sustainable development

Polysaccharide of Alocasia cucullata Exerts Antitumor Effect by Regulating Bcl-2, Caspase-3 and ERK1/2 Expressions during Long-Time Administration

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Chinese Journal of Integrative Medicine 2024年第1期30卷 52-61页

作者： ZHOU Qi-chun XIAO Shi-lin lin Ru-kun LI chan CHEN Zhi-jie CHEN Yi-fei LUO Chao-hua MO Zhi-xian lin Ying-bo School of Traditional Chinese Medicine Southern Medical UniversityGuangzhou(510515)China Clinical and Basic Research Team of TCM Prevention and Treatment of Non-Small Cell Lung Cancer the Second Clinical College of Guangzhou University of Chinese MedicineGuangzhou(510120)China Department of Chinese Medicine Zhujiang Hospital Affiliated to Southern Medical UniversityGuangzhou(510282)China Department of Pharmacy Jiangmen Central HospitalJiangmen(529000)China

Objective: To study the in vitro and in vivo antitumor effects of the polysaccharide of Alocasia cucullata(PAC) and the underlying mechanism. Methods: B16F10 and 4T1 cells were cultured with PAC of 40 μg/m L, and PAC was withdrawn after 40 days of administration. The cell viability was detected by cell counting kit-8. The expression of Bcl-2 and Caspase-3 proteins were detected by Western blot and the expressions of ERK1/2 mRNA were detected by quantitative real-time polymerase chain reaction(qRT-PCR). A mouse melanoma model was established to study the effect of PAC during long-time administration. Mice were divided into 3 treatment groups: control group treated with normal saline, positive control group(LNT group) treated with lentinan at 100 mg/(kg·d), and PAC group treated with PAC at 120 mg/(kg·d). The pathological changes of tumor tissues were observed by hematoxylin-eosin staining. The cell apoptosis of tumor tissues was detected by TUNEL staining. Bcl-2 and Caspase-3 protein expressions were detected by immunohistochemistry, and the expressions of ERK1/2, JNK1 and p38 mRNA were detected by qRT-PCR. Results: In vitro, no strong inhibitory effects of PAC were found in various tumor cells after 48 or 72 h of administration. Interestingly however, after 40 days of cultivation under PAC, an inhibitory effect on B16F10 cells was found. Correspondingly, the long-time administration of PAC led to downregulation of Bcl-2 protein(P <0.05), up-regulation of Caspase-3 protein(P<0.05) and ERK1 mRNA(P<0.05) in B16F10 cells. The above results were verified by in vivo experiments. In addition, viability of B16F10 cells under long-time administration culture in vitro decreased after drug withdrawal, and similar results were also observed in 4T1 cells. Conclusions: Long-time administration of PAC can significantly inhibit viability and promote apoptosis of tumor cells, and had obvious antitumor effect in tumor-bearing mice.

关键词： polysaccharide of Alocasia cucullata tumor cells Bcl-2 Caspase-3 ERK1/2 Chinese medicine

Telomere-to-telomere genome assemblies of two Chinese Baijiu-brewing sorghum landraces

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Plant Communications 2024年第6期5卷 9-12页

作者： Jiandong Bao Heng Zhang Fulin Wang lin Li Xueming zhu Junfeng Xu Yao Wang Zhijian Liu Guowei Zhai Heng Xu Fucheng lin Ying zhu State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products Zhejiang Academy of Agricultural SciencesHangzhou 310021ZhejiangChina Institute of Plant Protection and Microbiology Zhejiang Academy of Agricultural SciencesHangzhou 310021China Institute of Virology and Biotechnology Zhejiang Academy of Agricultural SciencesHangzhou 310021China College of Advances Agricultural Science Zhejiang A&F UniversityHangzhou 311300ZhejiangChin

Dear Editor,Sorghum(Sorghum bicolor[L.]Moench)(2n=20),a C4 droughttolerant cereal crop,is widely cultivated for food,feed,and biofuel,resulting in varieties with distinct morphological *** Sanger-sequencing-based sorghum reference genome of the inbred variety BTx623(grain sorghum)was initially released in 2009(base error<1 per 10 kb)(Paterson et al.,2009),and the most widely used version 3 assembly(base error<1 per 100 kb),consisting of 4773 contigs with 2679 unresolved gaps(~28 Mb)in 10 chromosomes,was improved by next-generation sequencing in 2017(McCormick et al.,2018).

关键词： Sorghum cultivated cereal

Regulating photothermal properties of near-infrared croconaine dyes by supramolecular assembly

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Nano Research 2024年第9期17卷 8560-8570页

作者： Yangge Ren Yue Lu Juanjuan Gao Yi Ding Bo zhu Xinyu Hou lin Jia Department of Polymer Materials School of Materials Science and EngineeringShanghai UniversityShanghai 200444China Department of Electronic Information Materials School of Materials Science and EngineeringShanghai UniversityShanghai 200444China

The photochemical and photophysical properties of near-infrared(NIR)dyes are significantly influenced by their aggregation state and mesoscopic ***,beyond chemical synthesis,the regulation mechanisms for the properties of NIR dyes,particularly with respect to photothermal properties of the aggregates,are not yet fully ***,we investigate the photothermal behaviors of croconaine-based(CroA)NIR dyes containing dipeptide or amino acids *** introduction of hydrogen bonding promotesπ-πstacking of croconaine center,which can efficiently regulate aggregation states and assembly structures in *** laser irradiation,CroA aggregates undergo aggregation-dissociation transition,the in-situ monomer generation process regulates two parameters of photothermal performance:heating rates and plateau photothermal *** study reveals the regulation effect of non-covalent bonding interactions on CroA aggregates,highlighting supramolecular assembly strategy not only facilitates to construct of photothermal nanomaterials with well-defined structures,but also provides an alternative and effective method for regulating photothermal performance of NIR dyes.

关键词： croconaine dye hydrogen bonding photothermal performance supramolecular assembly chirality

A Deep Neural Collaborative Filtering Based Service Recommendation Method with Multi-Source Data for Smart Cloud-Edge Collaboration Applications

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Tsinghua Science and Technology 2024年第3期29卷 897-910页

作者： Wenmin lin Min zhu Xinyi Zhou Ruowei Zhang Xiaoran Zhao Shigen Shen Lu Sun Alibaba Business School Hangzhou Normal UniversityHangzhou 311121China Blockchain Laboratory of Agricultural Vegetables Weifang University of Science and TechnologyShouguang 262700China School of Computer Science Qufu Normal UniversityRizhao 276827China School of Information Engineering Huzhou UniversityHuzhou 313000China

Service recommendation provides an effective solution to extract valuable information from the huge and ever-increasing volume of big data generated by the large cardinality of user ***,the distributed and rich multi-source big data resources raise challenges to the centralized cloud-based data storage and value mining approaches in terms of economic cost and effective service recommendation *** view of these challenges,we propose a deep neural collaborative filtering based service recommendation method with multi-source data(i.e.,NCF-MS)in this paper,which adopts the cloud-edge collaboration computing paradigm to build recommendation *** specifically,the Stacked Denoising Auto Encoder(SDAE)module is adopted to extract user/service features from auxiliary user profiles and service *** Multiple Layer Perceptron(MLP)module is adopted to integrate the auxiliary user/service features to train the recommendation ***,we evaluate the effectiveness of the NCF-MS method on three public *** experimental results show that our proposed method achieves better performance than existing methods.

关键词： deep neural collaborative filtering multi-source data cloud-edge collaboration application stackeddenoising auto encoder multiple layer perceptron

Experimental models for preclinical research in kidney disease

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Zoological Research 2024年第5期45卷 1161-1174页

作者： Jin Miao Huanhuan zhu Junni Wang Jianghua Chen Fei Han Weiqiang lin Kidney Disease Center First Affiliated HospitalZhejiang University School of MedicineInstitute of NephrologyZhejiang UniversityKey Laboratory of Kidney Disease Prevention and Control TechnologyZhejiang ProvinceZhejiang Clinical Research Center of Kidney and Urinary System DiseaseHangzhouZhejiang 310003China Department of Nephrology Center for Regeneration and Aging MedicineFourth Affiliated Hospital of School of Medicineand International School of MedicineInternational Institutes of MedicineZhejiang UniversityYiwuZhejiang 322000China

Acute kidney injury(AKI)and chronic kidney disease(CKD)are significant public health issues associated with a long-term increase in mortality risk,resulting from various etiologies including renal ischemia,sepsis,drug toxicity,and diabetes *** preclinical models have been developed to deepen our understanding of the pathophysiological mechanisms and therapeutic approaches for kidney *** these,rodent models have proven to be powerful tools in the discovery of novel therapeutics,while the development of kidney organoids has emerged as a promising advancement in the *** review provides a comprehensive analysis of the construction methodologies,underlying biological mechanisms,and recent therapeutic developments across different AKI and CKD ***,this review summarizes the advantages,limitations,and challenges inherent in these preclinical models,thereby contributing robust evidence to support the development of effective therapeutic strategies.

关键词： Acute kidney injury Chronic kidney disease Mouse models

Efficient piezo-catalytic dye degradation using piezoelectric 6H-SiC under harsh conditions

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Rare Metals 2024年第7期43卷 3173-3184页

作者： lin-lin Zhou Tao Yang Kang Wang Lai-Pan zhu En-Hui Wang Kuo-Chih Chou Hai-Long Wang Xin-Mei Hou Institute for Carbon Neutrality University of Science and Technology BeijingBeijing 100083China Institute of Steel Sustainable Technology Liaoning Academy of MaterialsShenyang 110000China Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of SciencesBeijing 101400China School of Materials Science Engineering Zhengzhou UniversityZhengzhou 450001China Beijing Advanced Innovation Center for Materials Genome Engineering Beijing University of Science and TechnologyBeijing 100083China

The development of novel piezoelectric catalysts against harsh conditions is indeed crucial for improving the piezo-catalytic degradation efficiency of colored organic dyes in *** this work,6H-SiC nanoparticles(NPs)are utilized to piezo-catalytic degrade rhodamine B(RhB)and methylene blue(MB)under ultrasonic vibration for the first *** degradation efficiency of RhB and MB reaches 98.8%and 98.7%within 80 *** piezoelectricity of 6H-SiC is comprehensively analyzed by the piezoresponse force microscope(PFM)and finite element method(FEM).The strong oxidizing active free radicals generated by the continuous piezoelectric polarized electric field of 6H-SiC,i.e.,·O_(2)^(-)and·OH,induce the decomposition reactions of colored organic dyes in *** the dyes are proven to degrade to harmless or less-harmful products gradually during the piezo-catalysis process by high-performance liquid chromatography tandem mass spectrometry(HPLC-MS).Moreover,RhB is also decomposed efficiently by 6HSiC NPs under acidic and alkaline *** results prove the feasibility of 6H-SiC for decomposing common water pollutants under harsh conditions and provide a new perspective for water purification.

关键词： Piezo-catalytic degradation 6H-SiC Rhodamine B(RhB) Methylene blue(MB) Harsh conditions