检索结果-南通市图书馆

Practice and understanding of developing new technologies and equipment for green and low-carbon production of oilfields

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Engineering Management 2019年第4期6卷 517-523页

作者： He LIU Jianwen YAN Siwei meng Qinghai YANG Zixiu YAO Shijia zhu Research Institute of Petroleum Exploration&Development Beijing 100083China

The core of China’s low-carbon development includes optimization of industrial structure,clean energy technologies,emission reduction technologies,and innovation of relevant systems and *** National Petroleum Corporation(CNPC)has always been a proactive participant in developing low-carbon economy,shouldering the responsibilities of safeguarding oil and gas supply,conserving energy,and reducing ***,CNPC fulfills those responsibilities as a substantial part of its overall *** by low carbon and driven by innovation,petroleum corporations have taken constant innovation of low-carbon technologies,especially the development of green and low-carbon petroleum engineering technologies and equipment,as major measures for energy conservation and emission ***-scale development mode o f unconventional resource anhydrous fracturing should be *** supercritical C 02 should be used to replace water for fracturing operation,in order to achieve multiple objectives of C 02 burying,conserve water resource,improve single well production and ultimate recovery,realizing reduced emission and efficient utilization o f C 02 *** lifting energy-saving and efficiencyincreasing technologies and injection-production technology in the same well should also be *** consumption of high water-cut wells is reduced to support the new low-carbon operation mode of high water-cut oilfields and realize energy saving and efficiency improvement during oil production by developing the operation efficiency of the lifting system and reducing the ineffective lifting of formation *** technologies have been widely recognized by local and international experts and have greatly enhanced CNPC's international *** study expounds the key technologies and equipment with regard to the development of green and low-carbon petroleum engineering and provide relevant suggestions.

关键词： low carbon energy conservation and emission reduction petroleum engineering technology petroleum equipment

Beyond ribosomal function:RPS6 deficiency suppresses cholangiocarcinoma cell growth by disrupting alternative splicing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2024年第9期14卷 3931-3948页

作者： Wenkang Fu Yanyan Lin Mingzhen Bai Jia Yao Chongfei Huang long Gao Ningning Mi Haidong Ma Liang Tian Ping Yue Yong Zhang Jinduo zhang Yanxian Ren Liyun Ding Lunzhi Dai Joseph WLeung Jinqiu Yuan Wenhua Zhang Wenbo meng The First School of Clinical Medicne Lanzhou UniversityLanzhou 730030China Department of General Surgery the First Hospital of Lanzhou UniversityLanzhou 730030China Key Laboratory of Biotherapy and Regenerative Medicine of Gansu Province the First Hospital of Lanzhou UniversityLanzhou 730000China School of Physical Science and Technology Lanzhou UniversityLanzhou 730000China National Clinical Research Center for Geriatrics and Department of General Practice State Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengdu 610041China Division of Gastroenterology UC Davis Medical Center and Sacramento VA Medical CenterSacramentoCA 95817USA Clinical Research Center Big Data Centerthe Seventh Affiliated HospitalSun Yat-sen UniversityShenzhen 518107China School of Life Sciences Lanzhou UniversityLanzhou 730000China

Cholangiocarcinoma(CCA)is a bile duct malignancy with a dismal *** study systematically investigated the role of the ribosomal protein S6(RPS6)gene,which is dependent in *** found that RPS6 upregulation in CCA tissues was correlated with a poor *** investigations have shown that alterations in RPS6 expression,both gain-and loss-of function could affect the proliferation of CCA *** xenograft tumor models,RPS6 overexpression enhances tumorigenicity,whereas RPS6 silencing reduces *** analysis using RNA-seq and proteomics elucidated downstream signaling pathways of RPS6 depletion by affecting the cell cycle,especially DNA *** followed by mass spectrometry has identified numerous spliceosome complex proteins associated with *** profiling revealed that RPS6 affects numerous alternative splicing(AS)events,and combined with RNA immunoprecipitation sequencing,revealed that minichromosome maintenance complex component 7(MCM7)binds to RPS6,which regulates its AS and increases oncogenic activity in *** RPS6 with vivo phosphorodiamidate morpholino oligomer(V-PMO)significantly inhibited the growth of CCA cells,patient-derived organoids,and subcutaneous xenograft *** together,the data demonstrate that RPS6 is an oncogenic regulator in CCA and that RPS6-V-PMO could be repositioned as a promising strategy for treating CCA.

关键词： Cholangiocarcinoma Ribosomal protein S6 Alternative splicing p53 Minichromosome maintenance complex component 7 Vivo morpholino Patient-derived organoids

Practical Internet Voting Protocol without Strong Physical Assumption

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Wuhan University Journal of Natural Sciences 2007年第1期12卷 177-180页

作者： meng Bo ZHANG Huanguo School of Computer South-Central University for Nation-alities Wuhan 430074 Hubei China School of Computer Wuhan University Wuhan 430072Hubei China

Internet voting protocols is the base of the Internet voting systems. In this paper a new practical Internet voting protocol is introduced. The proposed Internet voting protocol does not apply the strong physical assumptions and has the properties of privacy, completeness, soundness, fairness, invariableness, and universal verifiability, receipt-free and coercion-resistant. At the same time it solves some problems in other internet voting protocols and the verification progress of universal verifiability is simple and efficient.

关键词： information security voting protocol protocol security

我国互联网企业“数据协助”义务的困境与出路

在线全文

学校读者我要写书评

暂无评论

求是学刊 2022年第6期49卷 129-144页

作者：朱梦云华东交通大学高铁与区域发展研究院南昌330013 华东交通大学人文社会科学学院南昌330013

基于推动数据治理、促进数字正义和保障数据安全的需要,互联网企业在行政部门履行公共职能过程中应当负有必要的“数据协助”义务。然而,由于该义务在客观上涉及个人利益、企业利益和社会公共利益等不同法益,在理论上存在权利与义务、... 详细信息

基于推动数据治理、促进数字正义和保障数据安全的需要,互联网企业在行政部门履行公共职能过程中应当负有必要的“数据协助”义务。然而,由于该义务在客观上涉及个人利益、企业利益和社会公共利益等不同法益,在理论上存在权利与义务、自由与限制等价值理念冲突,在实践中存在履行义务主体不明、义务指向数据范畴不清、义务履行法律后果规定不一等问题,其尚存在一些实施困境与技术难题。因此,应在充分考量个人、企业和国家等不同主体的合法权益,确保我国互联网企业能够有效参与数字治理生态体系互动的前提下,从主体类型化、客体明晰化、程序规范化和体系设计逻辑化等角度,对企业“数据协助”义务的内容与路径予以廓清厘定,进而为打造多元数字治理格局、形成良性数字治理秩序提供理论支撑和实践依据。

关键词：执法监管数据协助数字治理法治理念

社会网络理论下“大众生产”组织的网络治理研究

在线全文

学校读者我要写书评

暂无评论

经济管理 2014年第5期40卷 70-79页

作者：孟韬孔令柱东北财经大学辽宁大连116025

大众生产是在web2.0信息技术环境下,在知识产品的生产领域中出现的一种新型的组织模式。大众生产的兴起正在重塑着经济生产主体与生产方式、企业创新模式与组织模式。在没有经济激励、正式组织的情况下,大众生产何以高效地创造出Linux... 详细信息

大众生产是在web2.0信息技术环境下,在知识产品的生产领域中出现的一种新型的组织模式。大众生产的兴起正在重塑着经济生产主体与生产方式、企业创新模式与组织模式。在没有经济激励、正式组织的情况下,大众生产何以高效地创造出Linux系统、维基百科、百度百科等复杂的知识产品?本文以社会网络理论为基础,通过对大众生产社区参与者进行问卷调查获得数据,对大众生产组织的网络治理机制进行了实证研究。研究论证了大众生产网络的结构、关系、认知维度作用于组织行为进而影响组织绩效的治理机制。因此,大众生产的项目管理者应当鼓励成员间加强交流合作,提高其对社区的认知水平,改善参与者的参与行为,进而提高大众生产的组织绩效,以此推动知识与技术创新。

关键词：大众生产网络嵌入网络治理社会网络

Ideal Cardiovascular Health is Inversely Associated with Subclinical Atherosclerosis: A Prospective Analysis

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2019年第4期32卷 260-271页

作者： WANG long NIU Jing Ya ZHAO Zhi Yun LI Mian XU Min LU Jie Li WANG Tian Ge CHEN Yu Hong WANG Shuang Yuan DAI meng LI Lin LIU Shan Shan WANG Wei Qing XU Yu BI Yu Fang National Clinical Research Center for Metabolic Diseases Shanghai Institute of Endocrine and Metabolic Diseasesand Department of Endocrine and Metabolic DiseasesRui-Jin HospitalShanghai Jiao Tong University School of Medicine

Objective Ideal cardiovascular health(CVH) could predict a lower risk of developing cardiovascular diseases. This study was conducted to investigate the association between ideal CVH and subclinical atherosclerosis in a population cohort of Chinese adults aged ≥ 40 years. Methods This study was designed as a cross-sectional analysis of 8,395 participants who had complete data at baseline and a prospective analysis of 4,879 participants who had complete data at 4.3 years of follow-up. Ideal CVH metrics were defined according to the American Heart Association. Subclinical atherosclerosis was evaluated by plaques in carotid arteries, carotid intima-media thickness(CIMT), brachial-ankle pulse wave velocity(baPWV), and urinary albumin-to-creatinine ratio(UACR). Results Both the prevalence and incidence of atherosclerosis measures were found to be decreased with increasing numbers of ideal CVH metrics at baseline(all P values for trend < 0.01). The levels of CIMT and UACR at follow-up showed an inverse and significant association with the numbers of ideal CVH metrics at baseline(both P values for trend < 0.05) but a borderline significant association with baPWV(P for trend = 0.0505). Taking participants with 0-1 ideal metric as reference, we found that participants with 5-6 ideal metrics had significantly lower risks of developing carotid plaques(odds ratio, OR = 0.46; 95% confidence interval, CI 0.27-0.79), increased CIMT(OR = 0.60; 95% CI 0.42-0.84), and increased baPWV(OR = 0.57; 95% CI 0.34-0.97) after full adjustments. A significant interactive effect of age and CVH was detected on CIMT and baPWV progression(both P values for interaction < 0.05). Conclusion The numbers of ideal CVH metrics showed a significant and inverse association with the risk of developing subclinical atherosclerosis in middle-aged and elderly Chinese adults, whereas its dose-response effect was attenuated in individuals aged ≥ 60 years and partially weakened in male participants.

关键词： Cardiovascular health Subclinical atherosclerosis Cohort

Electrochemically activated nickel-cobalt double hydroxide for aqueous ammonium-zinc hybrid battery

在线全文

学校读者我要写书评

暂无评论

Nano Research 2023年第2期16卷 2495-2501页

作者： Qing Pan Peng Hei Yu Song Jianming meng Chang Liu Xiao-Xia Liu Department of Chemistry Northeastern UniversityShenyang 110819China National Frontiers Science Center for Industrial Intelligence and Systems Optimization Northeastern UniversityShenyang 110819China Key Laboratory of Data Analytics and Optimization for Smart Industry(Northeastern University) Ministry of EducationShenyang 110819China

Aqueous rechargeable ammonium-ion(NH^(4+))batteries(AAIBs)with ammonium ions as charge carriers possess many advantages,yet the relatively low discharge capacities(e.g.,<200 mAh·g^(−1))of the reported NH_(4)^(+)host materials hinder the development of ***,we study the NH_(4)^(+)storage properties of an electrochemically activated NiCo double hydroxide(A-NiCo-DH)in neutral ammonium acetate electrolyte for the first *** activation process extracts the interlayer anions(NO3from the host material,providing additional cation accommodation sites for charge *** introduced H vacancies in A-−)NiCo-DH could activate the O sites,leading to the enhanced cation adsorption capability for the ***,A-NiCo-DH exhibits a high discharge capacity of 280.6 mAh·g^(−1)at 0.72 A·g^(−1)with good rate *** studies suggest A-NiCo-DH experiences a NH4+/H+coinsertion mechanism.A NH4+-Zn hybrid cell is assembled using A-NiCo-DH as the cathode and Zn foil as the anode,*** device delivers an energy density of 306 Wh·kg^(−1)at the power density of 745.8 W·kg^(−1)(based on the active mass of A-NiCo-DH).This work provides a new NH_(4)^(+)storage material and would push forward the development of aqueous NH4+-based batteries.

关键词： Ni-Co double hydroxide electrochemical activation charge storage mechanism high capacity ammonium-ion battery

Leakage Current Simulation of Insulating Thin Film Irradiated by a Nonpenetrating Electron Beam

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics Letters 2012年第4期29卷 221-224页

作者： ZHANG Hai-Bo LI Wei-Qin CAO meng Key Laboratory for Physical Electronics and Devices of MOE Department of Electronic Science and TechnologyXi’an Jiaotong UniversityXi’an 710049 School of Automation and Information Engineering Xi’an University of TechnologyXi’an 710048

We perform numerical simulations of the leakage current characteristics of an insulating thin film of SiO2 negatively charged by a low-energy nonpenetrating focused electron *** the formation of leakage current,electrons are demonstrated to turn from diffusion to drift after clearing the minimum potential barrier due to electron-hole *** the equilibrium state,the leakage current increases approximately linearly with the increasing primary beam current and *** also increases with the increasing film thickness and trap density,and with the decreasing electron mobility,in which the film thickness has a greater *** by some existing experiments,the simulation results provide a new perspective for the negative charging effects of insulating samples due to the low-energy focused electron beam.

关键词： film Electron linearly

Cryptosporidium parvum thrombospondin type 1 domain-containing protein 4(CpTSP4):Discovery and determination of a heparin-binding site(HBS) and contribution of HBS to the adhesion of sporozoites onto host cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cryptosporidium parvum thrombospondin type 1 domain-containi...