检索结果-南通市图书馆

Maternal smoking status during pregnancy and low birth weight in offspring:systematic review and meta-analysis of 55 cohort studies published from 1986 to 2020

在线全文

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2022年第3期18卷 176-185页

作者： Hong-Kun Di Yong Gan Kai Lu Chao Wang Yi zhu Xin meng Wen-Qi Xia Min-Zhi Xu Jing Feng Qing-Feng Tian Yan He Zhi-Qiang Nie Jun-An Liu Fu-Jian Song Zu-Xun Lu Department of Social Medicine and Health Management School of Public HealthTongji Medical CollegeHuazhong University of Science and TechnologyNo.13 Hangkong RoadWuhan 430030HubeiChina Tongji Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubeiChina School of Public Health Zhengzhou UniversityZhengzhouHenanChina Norwich Medical School Faculty of Medicine and Health ScienceUniversity of East AngliaNorwich NR47TJUK

Background Maternal smoking during pregnancy may be associated with low birth weight(LBW)in offspring and global risk estimates have not been summarized *** aimed to systematically explore evidence regarding maternal smoking and the LBW risk in offspring globally and examine possible causes of heterogeneity across relevant *** Comprehensive search of PubMed,Ovid Embase,Ovid Medline(R),and Web of science from inception until October 2021 was carried out.A random-effects meta-analysis was used to estimate the pooled odds ratio(OR)and corresponding 95%confidence interval(CI).Restricted cubic spline analysis with three knots was used to further examine the dose-response *** Literature searches yielded 4940 articles,of which 53 met inclusion criteria(comprising 55 independent studies).Maternal smoking during pregnancy was significantly associated with the risk of LBW in offspring(OR=1.89,95%CI=1.80-1.98).Furthermore,an obvious dose-response relationship between the amount of cigarettes daily smoked in pregnancy and the risk of LBW in offspring was *** results of subgroup analyses indicated that the risk of maternal smoking on LBW was larger in more recently conducted studies(P=0.020)and longer period of active smoking during pregnancy(P=0.002).No evidence of publication bias was *** In summary,maternal smoking in pregnancy was significantly associated with a higher risk of LBW in offspring on a global *** risk of maternal smoking on infant LBW seems to be increasing over time,and was higher with longer smoking duration throughout pregnancy and more cigarettes smoked daily.

关键词： Low birth weight Maternal smoking Meta-analysis Pregnancy

Carbon-based nanomaterials cause toxicity by oxidative stress to the liver and brain in Sprague-Dawley rats

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第6期35卷 54-64页

作者： Ying-Ying Xu Chan Jin meng Wu Jian-Ye Zhou Hui-Ling Wei Department of Gastroenterology China-Japan Friendship HospitalBeijing 100029China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China Institute of Particle and Nuclear Physics College of PhysicsHenan Normal UniversityXinxiang 453007China

Carbon-based nanomaterials have important research significance in various disciplines,such as composite materials,nanoelectronic devices,biosensors,biological imaging,and drug ***,the human and ecological risks associated with carbon-based nanomaterials have received increasing ***,the biological safety of carbon based nanomaterials has not been systematically *** this study,we used different types of carbon materials,namely,graphene oxide(GO),single-walled carbon nanotubes(SWCNTs),and multiwalled carbon nanotubes(MWCNTs),as models to observe their distribution and oxidative damage in *** results of Histopathological and ultrastructural examinations indicated that the liver and lungs were the main accumulation targets of these ***-μ-XRF analysis revealed that SWCNTs and MWCNTs might be present in the *** shows that the three types of carbon-based nanomaterials could cross the gas-blood barrier and eventually reach the liver *** addition,SWCNTs and MWCNTs could cross the blood-brain barrier and accumulate in the cerebral *** increase in ROS and MDA levels and the decrease in GSH,SOD,and CAT levels indicated that the three types of nanomaterials might cause oxidative stress in the *** suggests that direct instillation of these carbon-based nanomaterials into rats could induce ROS *** addition,iron(Fe)contaminants in these nanomaterials were a definite source of free ***,these nanomaterials did not cause obvious damage to the rat brain *** deposition of selenoprotein in the rat brain was found to be related to oxidative stress and Fe *** information may support the development of secure and reasonable applications of the studied carbon-based nanomaterials.

关键词： Carbon-based nanomaterials Oxidative stress Trace element distribution TEM SR-μ-XRF

在线全文

学校读者我要写书评

暂无评论

连铸结晶器非正弦振动波形构造及参数研究

中国机械工程 2007年第15期18卷 1779-1782页

作者：孟祥宁朱苗勇东北大学沈阳110004

基于最佳振动模式特点构造出连铸结晶器非正弦振动波形,分析了波形动力学特性,给出振动过程参数表达式,讨论了振动基本参数选取原则和确定方法,确定了1.8m/min拉速下振动基本参数值。研究表明,振动波形函数易于工程实现,波形动力学性能... 详细信息

基于最佳振动模式特点构造出连铸结晶器非正弦振动波形,分析了波形动力学特性,给出振动过程参数表达式,讨论了振动基本参数选取原则和确定方法,确定了1.8m/min拉速下振动基本参数值。研究表明,振动波形函数易于工程实现,波形动力学性能良好,振动波形和过程参数解析式为基本参数优化和提高控制精度创造了条件,振动基本参数的选取和确定为最大限度地发挥连铸机潜能提供了指导。

关键词：连铸结晶器非正弦振动振动波形振动参数

A proactive secret sharing scheme based on Chinese remainder theorem

在线全文

学校读者我要写书评

暂无评论

Frontiers of Computer Science 2021年第2期15卷 133-142页

作者： Keju meng Fuyou MIAO Yu NING Wenchao HUANG Yan XIONG Chin-Chen CHANG School of Computer Science and Technology University of Science and Technology of ChinaHefei230026China Department of Information Engineering and Computer Science Feng Chia UniversityTaichung40724China School of Computer Science and Technology Hangzhou Dianzi UniversityHangzhou310018China

If an adversary tries to obtain a secret s in a(t,n)threshold secret sharing(SS)scheme,it has to capture no less than t shares instead of the secret s ***,if a shareholder keeps a fixed share for a long time,an adversary may have chances to filch some shareholders’*** a proactive secret sharing(PSS)scheme,shareholders are supposed to refresh shares at fixed period without changing the *** this way,an adversary can recover the secret if and only if it captures at least t shares during a period rather than any time,and thus PSS provides enhanced protection to long-lived *** existing PSS schemes are almost based on linear SS but no Chinese Remainder Theorem(CRT)-based PSS scheme was *** paper proposes a PSS scheme based on CRT for integer ring to analyze the reason why traditional CRT-based SS is not suitable to design PSS ***,an ideal PSS scheme based on CRT for polynomial ring is also *** scheme utilizes isomorphism of CRT to implement efficient share refreshing.

关键词： proactive secret sharing Chinese remainder theorem polynomial ring integer ring isomorphism

Potential targeted therapy and diagnosis based on novel insight into growth factors,receptors,and downstream effectors in acute kidney injury and acute kidney injury-chronic kidney disease progression

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2020年第1期5卷 2373-2383页

作者： Li Gao Xiang Zhong Juan Jin Jun Li Xiao-ming meng The Key Laboratory of Major Autoimmune Diseases Anhui Institute of Innovative DrugsSchool of PharmacyAnhui Medical University230032 HefeiChina Department of Nephrology Sichuan Academy of Medical Sciences&Sichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of China610072 ChengduSichuanChina Department of Pharmacology Key Laboratory of Anti-inflammatory and ImmunopharmacologyMinistry of EducationAnhui Medical University230032 HefeiChina

Acute kidney injury(AKI)is defined as a rapid decline in renal function and is characterized by excessive renal inflammation and programmed death of resident *** shows high morbidity and mortality,and severe or repeated AKI can transition to chronic kidney disease(CKD)or even end-stage renal disease(ESRD);however,very few effective and specific therapies are available,except for supportive *** factors,such as epidermal growth factor(EGF),insulin-like growth factor(IGF),and transforming growth factor-β(TGF-β),are significantly altered in AKI models and have been suggested to play critical roles in the repair process of AKI because of their roles in cell regeneration and renal *** recent years,a series of studies have shown evidence that growth factors,receptors,and downstream effectors may be highly involved in the mechanism of AKI and may function in the early stage of AKI in response to stimuli by regulating inflammation and programmed cell ***,certain growth factors or correlated proteins act as biomarkers for AKI due to their sensitivity and ***,growth factors originating from mesenchymal stem cells(MSCs)via paracrine signaling or extracellular vesicles recruit leukocytes or repair intrinsic cells and may participate in AKI repair or the AKI-CKD *** addition,growth factor-modified MSCs show superior therapeutic potential compared to that of unmodified *** this review,we summarized the current therapeutic and diagnostic strategies targeting growth factors to treat AKI in clinical *** also evaluated the possibilities of other growth factorcorrelated molecules as therapeutic targets in the treatment of AKI and the AKI-CKD transition.

关键词： kidney diagnosis inflammation

Association of Genotyping of Bacillus cereus with Clinical Features of Post-Traumatic Endophthalmitis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Association of Genotyping of Bacillus cereus with Clinical F...

甘油施加比例对加热卷烟水分、烟碱和甘油分布的影响

第十二届全国免疫学学术大会

作者： zhu Gejing Hong meng Lou Yongliang Zheng Meiqin The Eye Hospital of Wenzhou Medical University China Ministry of Education Key Lab of Laboratory Medicine Wenzhou Medical University

Bacillus cereus is the second most frequent cause of post-traumatic bacterial *** genotyping of *** associated with gastrointestinal infections has been reported,little is known about the *** clinical isolates associated with post-traumatic *** is largely due to the limited number of clinical strains available isolated from infected tissues of patients with post-traumatic *** this study,we report successful isolation of twenty-four *** strains from individual patients with different disease severity of post-traumatic *** analysis showed that all strains could be categorized into three genotypes(GTⅠ,GTⅡ and GTⅢ) and the clinical score showed significant differences among these *** then further performed genotyping using the vrrA gene,etablished a vitro model of bateroidal endophthalmitis to investigate the toxic effects of different *** clinical isolates on muller cells and evaluated possible correlation of genotype,virulence phenotype and the clinical features of ***-caused post-traumatic *** found that the disease of onset,final vision acuity and virulence phenotype were significantly different among the three *** results suggested that the vrrA gene may play a significant role in the pathogenesis of endophthalmitis,and genotyping of *** has the potential for predicting clinical manifestation and prognosis of *** the best of our knowledge,this is the first report of isolation of large numbers of clinical isolates of *** from patients with *** work sets the foundation for future investigation of the pathogenesis endophthalmitis caused by *** infection.

关键词： B. cereus Post-Traumatic Endophthalmitis

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

食品与机械 2022年第10期38卷 43-49页

作者：朱龙杰张媛曹毅秦艳华刘梦梦朱怀远江苏中烟工业有限责任公司技术中心江苏南京210019

目的:优化加热卷烟烟草薄片的工艺参数。方法:制备了甘油添加比例为5%~30%的12个梯度等级的加热卷烟烟草薄片,制成加热卷烟烟支。使用GC-TCD方法检测加热卷烟烟气、滤嘴冷凝段和烟芯段中水分、烟碱和甘油质量,分析主要成分的质量分布特... 详细信息

目的:优化加热卷烟烟草薄片的工艺参数。方法:制备了甘油添加比例为5%~30%的12个梯度等级的加热卷烟烟草薄片,制成加热卷烟烟支。使用GC-TCD方法检测加热卷烟烟气、滤嘴冷凝段和烟芯段中水分、烟碱和甘油质量,分析主要成分的质量分布特点,以及释放率、截留率和转移率。结果:加热卷烟烟草薄片在5%~30%甘油添加比例下,水分释放率较高为88.6%~92.3%,主要分布在烟气和滤嘴冷凝段;烟碱释放率次之,为25.5%~34.2%,主要分布在滤嘴冷凝段和烟芯段;甘油释放率最低,为13.9%~21.3%,主要分布在烟芯段。结论:当烟草薄片选择10%~18%的甘油添加比例时,加热卷烟的烟碱和甘油具有较高的转移率和较低的截留率。

关键词：加热卷烟烟草薄片甘油施加比例质量分布释放率截留率转移率

维普期刊数据库博看期刊

A New Taxoid from Microbial Transformation

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 1997年第12期8卷 0-0页

作者： Hong XU Ke Di CHENG Wei Shuo FANG Ping zhu Chao meng(Key Laboratory of Biosynthesis of Natural Products, Ministry of Public Health)(Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050) Chinese Acad Med Sci Inst Mat Med Minist Publ Hlth Key Lab Biosynth Nat Prod Beijing 100050 Peoples R China Peking Union Med Coll Beijing 100050 Peoples R China

A new taxoid taxa-4(20), 11-diene-2α, 5β, 10β, 14β-tetraol-2α, 14β-diacetate (sinenxan H) (1) was obtained by biotransformation of taxa-4(20), 11-diene-2α, 5α, 10β, 14β-tetraol-2α, 5α, 10β, 14β-tetraacet... 详细信息

关键词： ppm A New Taxoid from Microbial Transformation

Understanding the mechanism of capacity increase during early cycling of commercial NMC/graphite lithium-ion batteries

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2022年第11期31卷 34-44,I0003页

作者： Jia Guo Yaqi Li Jinhao meng Kjeld Pedersen Leonid Gurevich Daniel-Ioan Stroe AAU Energy Aalborg UniversityAalborg9220Denmark Department of Materials and Production Aalborg UniversityAalborg 9220Denmark College of Electrical Engineering Sichuan UniversityChengdu 610065SichuanChina

A capacity increase is often observed in the early stage of Li-ion battery *** study explores the phenomena involved in the capacity increase from the full cell,electrodes,and materials perspective through a combination of non-destructive diagnostic methods in a full cell and post-mortem analysis in a coin *** results show an increase of 1%initial capacity for the battery aged at 100%depth of discharge(DOD)and 45℃.Furthermore,large DODs or high temperatures accelerate the capacity *** the incremental capacity and differential voltage(IC-DV)analysis,we concluded that the increased capacity in a full cell originates from the graphite ***,graphite/Li coin cells show an increased capacity for larger DODs and a decreased capacity for lower DODs,thus in agreement with the full cell ***-mortem analysis results show that a larger DOD enlarges the graphite dspace and separates the graphite layer structure,facilitating the Li+diffusion,hence increasing the battery capacity.

关键词： Capacity increasing Lithium-ion battery Full cell Coin cell Graphite anode