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基于进化HMM模型的动态Agent系统建模方法

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控制与决策 2006年第2期21卷 189-192页

作者：唐健朱纪红孙增圻清华大学计算机科学与技术系北京100084 清华大学智能技术与系统国家重点实验室北京100084

提出一种基于隐式M arkov模型(HMM)的进化建模方法.使用进化算法随机搜索HMM的模型空间,自动选择HMM的结构和参数,完成对动态智能体系统行为的建模,学习智能体对周围环境的分割和反映方式.实验结果表明,该方法可以很好地搜索HMM的模型空... 详细信息

提出一种基于隐式M arkov模型(HMM)的进化建模方法.使用进化算法随机搜索HMM的模型空间,自动选择HMM的结构和参数,完成对动态智能体系统行为的建模,学习智能体对周围环境的分割和反映方式.实验结果表明,该方法可以很好地搜索HMM的模型空间,并且避免了人工确定HMM模型结构的困难和手工设计模型所需的多次反复.

关键词：隐式Markov模型进化算法智能体建模

Association of TRMT2B gene variants with juvenile amyotrophic lateral sclerosis

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Frontiers of Medicine 2024年第1期18卷 68-80页

作者： Yanling Liu Xi He Yanchun Yuan Bin Li Zhen Liu Wanzhen Li Kaixuan Li Shuo Tan Quan zhu Zhengyan Tang Feng Han Ziqiang Wu Lu Shen Hong jiang Beisha Tang jian Qiu Zhengmao Hu Junling Wang Department of Neurology Xiangya HospitalCentral South UniversityJiangxiNational Regional Center for Neurological DiseasesNanchang330038China Provincial Laboratory for Diagnosis and Treatment of Genitourinary System Disease Department of UrologyXiangya HospitalCentral South UniversityChangsha410078China Department of Orthopedics The First Affiliated HospitalZhejiang University School of MedicineHangzhou310002China Department of Neurology Xiangya HospitalCentral South UniversityChangsha410078China National Clinical Research Center for Geriatric Diseases Xiangya HospitalCentral South UniversityChangsha410008China Key Laboratory of Hunan Province in Neurodegenerative Disorders Central South UniversityChangsha410008China Center for Medical Genetics School of Life SciencesCentral South UniversityChangsha410008China Engineering Research Center of Hunan Province in Cognitive Impairment Disorders Central South UniversityChangsha410078China Hunan International Scientific and Technological Cooperation Base of Neurodegenerative and Neurogenetic Diseases Changsha410078China Hunan Key Laboratory of Molecular Precision Medicine Xiangya HospitalCentral South UniversityChangsha410078China

Amyotrophic lateral sclerosis(ALS)is a fatal neurodegenerative disease characterized by progressive degeneration of motor neurons,and it demonstrates high clinical heterogeneity and complex genetic architecture.A variation within TRMT2B(c.1356G>T;p.K452N)was identified to be associated with ALS in a family comprising two patients with juvenile ALS(JALS).Two missense variations and one splicing variation were identified in 10 patients with ALS in a cohort with 910 patients with ALS,and three more variants were identified in a public ALS database including 3317 patients with ALS.A decreased number of mitochondria,swollen mitochondria,lower expression of ND1,decreased mitochondrial complex I activities,lower mitochondrial aerobic respiration,and a high level of ROS were observed functionally in patient-originated lymphoblastoid cell lines and TRMT2B interfering HEK293 ***,TRMT2B variations overexpression cells also displayed decreased *** conclusion,a novel JALS-associated gene called TRMT2B was identified,thus broadening the clinical and genetic spectrum of ALS.

关键词： TRMT2B amyotrophic lateral sclerosis mitochondrial complex I tRNA methylation reactive oxygen species

聚甲基丙烯酸甲酯在固体燃料冲压发动机中的燃面退移速率影响因素研究

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兵工学报 2015年第9期36卷 1632-1639页

作者：陈雄朱国强郑健南京理工大学机械工程学院江苏南京210094 南京晨光集团有限责任公司江苏南京210006

采用数值计算与实验研究相结合的方法,对聚甲基丙烯酸甲脂(PMMA)在固体燃料冲压发动机中的燃速影响因素开展了研究。重点分析了来流空气质量通量和固体燃料装药内径对PMMA燃料平均燃速和局部燃速的影响。研究表明:固体燃料表面的温度、... 详细信息

采用数值计算与实验研究相结合的方法,对聚甲基丙烯酸甲脂(PMMA)在固体燃料冲压发动机中的燃速影响因素开展了研究。重点分析了来流空气质量通量和固体燃料装药内径对PMMA燃料平均燃速和局部燃速的影响。研究表明:固体燃料表面的温度、热流密度和局部燃面退移速率沿轴线方向均呈现先逐渐增大后逐渐减小的趋势,极值出现在回流区末端的再附着点附近;固体燃料表面的局部燃面退移速率随装药内径增大而减小,但随空气质量通量的增大而增大;燃料平均燃速与来流空气质量通量呈幂函数递增关系,与固体燃料装药内径呈幂函数递减关系;数值计算和实验得到的影响变化规律吻合较好,但计算值比实验值稍微偏高,最大误差不超过10%.研究结果对固体燃料冲压发动机燃烧室的优化设计具有重要的参考价值。

关键词：兵器科学与技术固体燃料冲压发动机聚甲基丙烯酸甲脂燃面退移速率

The Contribution of Extreme Precipitation to the Total Precipitation in China

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Atmospheric and Oceanic Science Letters 2012年第6期5卷 499-503页

作者： SUN jian-Qi Nansen-zhu International Research Centre Institute of Atmospheric Physics Chinese Academy of Sciences Beijing 100029 China

Using daily precipitation data from weather stations in China, the variations in the contribution of extreme precipitation to the total precipitation are analyzed. It is found that extreme precipitation accounts for approximately one third of the total precipitation based on the overall mean for China. Over the past half century, extreme precipitation has played a dominant role in the year-to-year variability of the total precipitation. On the decadal time scale, the extreme precipitation makes different contributions to the wetting and drying regions of China. The wetting trends of particular regions are mainly attributed to increases in extreme precipitation; in contrast, the drying trends of other regions are mainly due to decreases in non-extreme precipitation.

关键词： precipitation extreme precipitation decadal variability

Prediction of PM2.5 Concentration Based on Bayesian Optimization Random Forest

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Prediction of PM2.5 Concentration Based on Bayesian Optimiza...

Tripodal Tris（porphyrin-urea） as a Receptor for Fullerene

第43届中国控制会议

作者： Yingji deng Pengfei Zhi Wanlu zhu Taize Sang Yuanjiang Li jiangsu University of Science and Technology jiangsu Daqo Cubicle-Type Substation Technology Co. Ltd.

Nowadays, people pay more and more attention to air quality, and smog as a serious air pollution phenomenon has received greater attention. As the main culprit of haze phenomenon and an important indicator of air quality, it is of great significance to forecast PM2.5. Aiming at the prediction of PM2.5 concentration, this paper proposes a method of using random forest algorithm to build a regression prediction model and then predict PM2.5 concentration. This method mainly uses meteorological factors related to PM2.5(such as dew point, temperature, humidity, etc.) and historical data of PM2.5 concentration in the past three hours as input to build the model. Forecast future hourly PM2.5 concentrations. In this paper, the random forest model is successfully constructed, and the Bayesian algorithm is used to optimize the random forest model, and the PM2.5 concentration is well predicted. At the same time, this paper also constructs the decision tree, support vector machine, intelligent gray Wolf algorithm optimized random forest model and Bayes algorithm optimized random forest model to compare. The superiority of Bayesian algorithm in optimizing stochastic forest model is proved.

关键词： Integrated learning Random forest PM2.5 concentration prediction Bayesian optimization algorithm

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Tripodal Tris（porphyrin-urea） as a Receptor for Fullerene

基于非分样ridgelet标架的图像滤噪恢复新算法的研究

全国第十六届大环化学暨第八届超分子化学学术讨论会

作者： Xiang Fang Yi-Zhou zhu jian-Yu Zheng State Key Laboratory and Institute of Elemento-Organic Chemistry Nankai University

＜正＞Trapping fullerenes byπ-electronic hosts is of great importance because of their potential applications such as extraction,solubilization and chemical modification of *** which get largeπ-conjugated system have been attracted as an ideal candidate for the design of host *** or acyclic porphyrin arrays have been ***,we report a tripodal tris（porphyrin-urea） as a

关键词： porphyrin C60 tripodal structure

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光学技术 2006年第1期32卷 34-38页

作者：张建贵邓胜前陈凌剑刘蓉南方医科大学生物医学工程系图像教研室广州510515 湖南商学院物流研究所长沙410205 长沙理工大学长沙410083

提出了一种基于非分样ridgelet标架的图像噪声滤除(UDRIFDA)的新算法。ridgelet标架的特点是:基函数不可分离变量且具有很强的方向性,能够实现对沿直线奇性的有效描述。离散非分样ridgelet标架是通过离散Radon变换切片上的一维非分样小... 详细信息

提出了一种基于非分样ridgelet标架的图像噪声滤除(UDRIFDA)的新算法。ridgelet标架的特点是:基函数不可分离变量且具有很强的方向性,能够实现对沿直线奇性的有效描述。离散非分样ridgelet标架是通过离散Radon变换切片上的一维非分样小波变换标架来实现的。由于非分样小波变换具有位移不变性,能够很好地刻画多尺度下一维信号的局部特征,基于一维非分样小波变换的软阈值去噪算法能够有效地降低一维信号急剧变化处所产生的震荡现象,故基于非分样ridgelet标架的图像滤噪算法能够大大降低恢复图像上的伪影,有效的克服了文献[1]中分样ridgelet标架滤噪算法(DRITDA)的缺陷。数值实验表明新算法较DRITDA和2D-DWT算法更能提高恢复图像的信噪比和视觉质量。

关键词： ridgelet标架图像滤噪非分样小波变换离散Radon变换

Are polymorphisms of N-acetyltransferase genes susceptible to primary liver cancer in Luoyang, China?

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World Journal of Gastroenterology 2005年第10期11卷 1457-1462页

作者： Xiu-FengZhang jian-ChaoBian Xiao-YanZhang zhu-MeiZhang Fengjiang Qi-MinWang Qi-JunWang Yan-YanCao Bo-MingTang DepartmentofEpidemiology SchoolofPublicHealthFudanUniversityShanghai200032China Departmentof.Epidemiology LuoyangCenterforDiseaseControlandPreventionLuoyang471000HenanProvinceChina

AIM: To identify whether the polymorphisms of the Nacetyltransferase (NAT) genes are susceptible to primary liver cancer (PLC) in Luoyang, a PLC low-incidence area of ***: The NAT1 and NAT2 genotypes of 96 PLC cases and 173 controls were determined by *** interaction between NAT1 or NAT2 and environmental risk factors were analyzed based on case control ***: Compared to the control group, the frequencies of alleles NAT1*3, NAT1*4, NAT1*10, NAT1*14B and alleles NAT2*4, NAT2*6, NAT2*7 in PLC group showed no statistically significant difference (x2 = 2.61 and 4.16,respectively, both P＞0.05). The frequencies of NAT1 genotypes NAT1*3/*3, NAT1*3/*4, NAT1*3/*10,NAT1*3/*14B, NAT1*4/*4, NAT1*4/*10, NAT1*4/*14B,NAT1*10/*10, NAT1*10/*14B, and NAT2 genotypes NAT2*4/*4, NAT2*4/*6, NAT2*4/*7, NAT2*6/*6,NAT2*6/*7 and NAT2*7/*7 also had no statistically significant difference between the two groups (x2 = 11.86 and 2.94respectively both, P＞0.05). Neither the frequencies of rapid and slow NAT1 acetylators nor the frequencies of rapid and slow NAT2 acetylators were significantly different between the two groups (x2 = 0.598 and 0.44,respectively, both P＞0.05). The interaction betweenNAT1*10 and occupational exposures was found significant with an odds ratio of 3.40 (x2 = 8.42, P = 0.004,OR 95%CI:1.03-11.22). But no interaction was found between NAT2 and any environmental risk ***: The polymorphisms of NAT1 and NAT2are not susceptible to PLC in Luoyang. Allele NAT1*10interacts with occupational exposures.

关键词： Polymorphisms N-acetyltransferase genes Primary liver cancer

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外国语 2007年第1期30卷 59-66页

作者：朱健平湖南大学外国语学院长沙410082

本文运用伊塞尔的“隐含读者”概念探讨了目的语文本与源语文本的关系,指出两种文本之间有着不可否定的历史渊源关系。任何目的语文本都是脱胎于某个源语文本的文本。在整个翻译过程中,源语文本既起着触发器的作用,又起着控制器的作用... 详细信息

本文运用伊塞尔的“隐含读者”概念探讨了目的语文本与源语文本的关系,指出两种文本之间有着不可否定的历史渊源关系。任何目的语文本都是脱胎于某个源语文本的文本。在整个翻译过程中,源语文本既起着触发器的作用,又起着控制器的作用。但同时,任何目的语文本都是作为现实读者的译者对源语文本进行解释的结果。作为这种结果,每一个目的语文本都只是其源语文本所预构的诸多目的语文本之一,只是实现了源语文本可能被实现的诸多实现方式之一,而非源语文本的全部。

关键词：翻译隐含读者目的语文本源语文本关系