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Fluid property identification of the Lower Cretaceous reservoirs with complex oil-water contacts in Deseo Basin,Chad

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Energy Geoscience 2024年第1期5卷 89-98页

作者： Xinxin Zhang lianfeng zhu Tianjiao Wang Xiaokang Shi Bo Han Jian shen Hailei Gao Mud logging company Great Wall Drilling Company Ltd.CNPCLiaoningPanjin124010China CNPC Latin America Ltd. Beijing100034China CNPC Andes(Ecuador)Ltd. Beijing100034China

Recently,exploration breakthroughs have been made in the Lower Cretaceous sandstone reservoirs in the Doseo Basin,but the identification of reservoir fluid property is difficult due to variable reservoir lithology,complex oil-water contact within and faint responses of the oil zone,which causes the lower accuracy of reservoir fluid property identification with conventional mudlogging and wirelogging *** the geochemical logging,fluorescent logging,mud logging and cutting logging technology,in combination with formation test data,this paper distinguishes the crude oil types,analyzes the logging response characteristics of oil zone after water washing,and establishes the interpretation charts and parameter standards for reservoir fluid *** crude oil can be divided into two types,namely viscous-heavy and thin-light,based on total hydrocarbon content and component concentration tested by mud logging,features of pyrolysis gas chromatogram and fluorescence *** general characteristics of oil layers experienced water washing include the decrease of total hydrocarbon content and component concentration from mud logging,the decrease of S1 and PS values from geochemical logging,the decrease of hydrocarbon abundance and absence of some light components in pyrolysis gas chromatogram,and the decrease of fluorescence area and intensity from fluorescence *** to crude oil types,the cross plots of S1 versus peak-baseline ratio,and the cross plots of rock wettability versus fluorescence area ratio are drawn and used to interpret reservoir fluid ***,the standards of reservoir fluid parameter are established combining with the parameters of PS and the parameters in above charts,and comprehensive multiparameter correlation in both vertical and horizontal ways is also performed to interpret reservoir fluid *** application in the Doseo Basin achieved great success,improving interpretation ability of fluid property

关键词： Doseo Basin Reservoir interpretation Oil-water contact Fluid property Crude oil type

Physiological and Proteomic Analyses Reveal Effects of Putrescine-Alleviated Aluminum Toxicity in Rice Roots

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Rice science 2021年第6期28卷 579-593,I0040-I0048页

作者： zhu Chunquan HU Wenjun CAO Xiaochuang zhu lianfeng KONG Yali JIN Qianyu shen Guoxin WANG Weipeng ZHANG Hui ZHANG Junhua State Key Laboratory of Rice Biology China National Rice Research InstituteHangzhou 310006China State Key Laboratory far Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products Zhejiang Academy of Agricultural SciencesHangzhou 310021China Agricultural Resources and Environment Institute Jiangsu Academy of Agricultural SciencesNanjing 210014China College of Environmental and Resource Science Shanxi UniversityTaiyuan 030006China

The effects of putrescine on improving rice growth under aluminum(Al)toxicity conditions have been previously demonstrated,however,the underlying mechanism remains *** this study,treatment with 50 pmol/L Al significantly decreased rice root growth and whole rice dry weight,inhibited Ca2+uptake,decreased ATP syn thesis,and in creased Al,H2O2 and malon dialdehyde(MDA)con tents,whereas the application of putrescine mitigated these negative *** increased root growth and total dry weight of rice,reduced total Al content,decreased H2O2 and MDA contents by increasing antioxidant enzyme(superoxide dismutase,peroxidase,catalase and glutathione S・transferase)activities,increased Ca2+uptake and energy product!oru Proteomic analyses using data-independent acquisition successfully identified 7934 proteins,and 59 representative proteins exhibiting fold-change values higher than 1.5 were randomly *** the results of the proteomic and biochemical analyses,we found that putrescine significantly inhibited ethylene biosynthesis and phosphorus uptake in rice roots,increased pectin methylation,decreased pectin content and apoplastic Al deposit!on in rice *** also alleviated Al toxicity by repairing damaged DNA and increasing the proteins involved in maintaining plasma membra ne integrity and normal cell *** fin dings improve our understanding of how putrescine affects the rice response to Al toxicity,which will facilitate further studies on environmental protection,crop safety,in novations in rice performance and real-world producti on.

关键词： aluminum toxicity antioxidant enzyme data-independent analysis putrescine proteomics rice

RBF-based cluster-head selection for wireless sensor networks

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Journal of Southeast University(English Edition) 2006年第4期22卷 451-455页

作者：朱晓荣沈连丰东南大学移动通信国家重点实验室南京210096

The radial basis function （RBF）, a kind of neural networks algorithm, is adopted to select clusterheads. It has many advantages such as simple parallel distributed computation, distributed storage, and fast learning. Four factors related to a node becoming a cluster-head are drawn by analysis, which are energy （ energy available in each node）, number （the number of neighboring nodes）, centrality （ a value to classify the nodes based on the proximity how central the node is to the cluster）, and location （the distance between the base station and the node）. The factors are as input variables of neural networks and the output variable is suitability that is the degree of a node becoming a cluster head. A group of cluster-heads are selected according to the size of network. Then the base station broadcasts a message containing the list of cluster-heads＇ IDs to all nodes. After that, each cluster-head announces its new status to all its neighbors and sets up a new cluster. If a node around it receives the message, it registers itself to be a member of the cluster. After identifying all the members, the cluster-head manages them and carries out data aggregation in each cluster. Thus data flowing in the network decreases and energy consumption of nodes decreases accordingly. Experimental results show that, compared with other algorithms, the proposed algorithm can significantly increase the lifetime of the sensor network.

关键词： sensor networks radial basis function cluster-head selection

A Plant Immune Receptor Adopts a Two-Step Recognition Mechanism to Enhance Viral Effector Perception

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Molecular Plant 2019年第2期12卷 248-262页

作者： Jia Li Haining Huang Min zhu shen Huang Wenhua Zhang Savithramma P. Dinesh-Kumar xiaorong Tao Department of Plant Pathology Nanjing Agricultural University Nanjing 210095 P. R. China College of Life Science Nanjing Agricultural University Nanjing 210095 P. R. China Department of Plant Biology and The Genome Center College of Biological Sciences University of California Davis CA USA

Plant intracellular nucleotide binding leucine-rich repeat (NLR) immune receptors play critical roles in pathoge n surveillance. Most plant NLRs characterized so far were found to use a single domain/sensor to recognize pathogen effectors. Here we report that the Sw-5b NLR immune receptor uses two distinct domains to detect the viral movement protein NSm encoded by tospovirus. In addition to its leucine-rich repeat (LRR) domain that has been previously reported, the N-terminal Solanaceae domain (SD) of Sw- 5b also interacts with NSm and a conserved 21-amino-acid region of NSm (NSm^21). The specific interaction between Sw-5b SD and NSm is required for releasing the inhibitory effect of coiled-coil domain on the NBARC- LRR region. Furthermore, we found that the binding of NSm affects the nucleotide binding activity of the NB-ARC-LRR in vitro, while Sw-5b NB-ARC-LRR is activated only when NSm and NSm^21 levels are high. Interestingly, Sw-5b SD could significantly enhanee the ability of the NB-ARC-LRR to detect low levels of NSm effector and facilitate its activation and induction of defense response. An Sw-5b SD mutant that is disrupted in NSm recognition failed to enhance the ability of the NB-ARC-LRR to sense low levels of NSm and NSm^21 . Taken together, our results suggest that Sw-5b SD functions as an extra sensor and the NB-ARC-LRR as an activator, and that Sw-5b NLR adopts a two-step recog nition mechanism to enhance viral effector perception.

关键词： plant innate immunity nucleotide binding leucine-rich repeat (NLR) immune receptors Solanaceae domain (SD) pathogen perception two-step recognition defense response

Optimal design of the link lengths for a planar parallel manipulator

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Computer Aided Drafting,Design and Manufacturing 2012年第4期22卷 74-80页

作者： zhu xiaorong shen Huiping School of Mechanical and Energy Engineering Changzhou University

This paper addresses geometry design of a new kind of 2-DOF parallel manipulator actuated horizontally by linear actua- tors. The first step of the optimum design involves developing a non-dimensional structure of the planar 2-DOF parallel manipulator. The global conditioning index, global velocity index, global stiffness index and global payload index of the 2-DOF parallel manipu- lators are investigated, and the geometrical parameters without dimension are determined with respect to the specification on per- formances. Finally, based on the optimum non-dimensional result, the optimum dimensional parameters are achieved which is suit- able for the desired workspace. The optimum methodology of this paper is convenient and can be extended to other parallel mecha-

关键词： parallel manipulator kinematics design space performance index optimum design

A tactical nanomissile mobilizing antitumor immunity enables neoadjuvant chemo-immunotherapy to minimize postsurgical tumor metastasis and recurrence

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Acta Pharmaceutica Sinica B 2023年第2期13卷 804-818页

作者： Tao He Mingxing Hu Shunyao zhu Meiling shen xiaorong Kou Xiuqi Liang Lu Li Xinchao Li Miaomiao Zhang Qinjie Wu Changyang Gong State Key Laboratory of Biotherapy and Cancer Center West China HospitalSichuan UniversityChengdu 610041China

Neoadjuvant chemotherapy has become an indispensable weapon against high-risk resectable cancers,which benefits from tumor ***,the utility of chemotherapeutics alone as a neoadjuvant agent is incapable of generating durable therapeutic benefits to prevent postsurgical tumor metastasis and ***,a tactical nanomissile(TALE),equipped with a guidance system(PD-L1 monoclonal antibody),ammunition(mitoxantrone,Mit),and projectile bodies(tertiary amines modified azobenzene derivatives),is designed as a neoadjuvant chemo-immunotherapy setting,which aims at targeting tumor cells,and fast-releasing Mit owing to the intracellular azoreductase,thereby inducing immunogenic tumor cells death,and forming an in situ tumor vaccine containing damage-associated molecular patterns and multiple tumor antigen epitopes to mobilize the immune *** formed in situ tumor vaccine can recruit and activate antigen-presenting cells,and ultimately increase the infiltration of CD8^(+)T cells while reversing the immunosuppression ***,this approach provokes a robust systemic immune response and immunological memory,as evidenced by preventing 83.3%of mice from postsurgical metastasis or recurrence in the B16-F10 tumor mouse ***,our results highlight the potential of TALE as a neoadjuvant chemo-immunotherapy paradigm that can not only debulk tumors but generate a long-term immunosurveillance to maximize the durable benefits of neoadjuvant chemotherapy.

关键词： Neoadjuvant Chemotherapy Immunotherapy Mitoxantrone Vaccine Azobenzene derivatives Reduction responsive Melanoma

基于数据挖掘的RPMA低功耗广域网网络规划方法

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通信学报 2019年第3期40卷 28-35页

作者：朱晓荣沈瑶南京邮电大学江苏省无线通信重点实验室江苏南京210003

针对RPMA低功耗广域网基站密度大、业务分布不均匀等特点,提出了一种基于数据挖掘的网络规划方法。首先,利用提升回归树算法建立了信号质量预测模型,用于提取网络的覆盖分布空间模式;然后,针对覆盖分布空间模式,采用加权k-centroids分... 详细信息

针对RPMA低功耗广域网基站密度大、业务分布不均匀等特点,提出了一种基于数据挖掘的网络规划方法。首先,利用提升回归树算法建立了信号质量预测模型,用于提取网络的覆盖分布空间模式;然后,针对覆盖分布空间模式,采用加权k-centroids分簇算法得到适应当前模式的最优基站部署;最后,根据总目标函数判定得到最终的基站拓扑。通过真实数据集的仿真实验结果表明,与传统的网络规划方法相比,所提的方法很好地提升低功耗广域网网络的覆盖质量。

关键词：低功耗广域网提升回归树加权k-centroids 基站部署

3T1R解耦并联机构动力学与惯量耦合特性分析

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农业机械学报 2023年第9期54卷 448-458页

作者：朱小蓉赵磊沈惠平常州大学机械工程学院常州213164

对一种3T1R解耦并联机构的动力学性能及其惯量耦合强度进行了分析。对机构进行运动学分析,给出了机构的位置正反解方程,得到动平台的雅可比矩阵,推导了机构各构件的速度、加速度;基于牛顿-欧拉法,考虑构件重力以及外负载,建立了机构逆... 详细信息

对一种3T1R解耦并联机构的动力学性能及其惯量耦合强度进行了分析。对机构进行运动学分析,给出了机构的位置正反解方程,得到动平台的雅可比矩阵,推导了机构各构件的速度、加速度;基于牛顿-欧拉法,考虑构件重力以及外负载,建立了机构逆向动力学模型,并用ADAMS软件进行了仿真验证;基于所建的逆向动力学模型,分析了加速度和动平台姿态角对支链驱动力的影响;基于关节空间的惯量矩阵,建立了惯量耦合强度评价指标,分析了其在工作空间内的分布规律,并与降耦前Quadrupteron机构的惯量耦合强度进行了对比分析。结果表明,结构降耦不仅降低了支链间的耦合强度,而且整个工作空间内惯量耦合强度的分布更为一致,提升了机构动态性能的各向同性。

关键词：并联机构牛顿-欧拉法逆向动力学模型惯量耦合强度

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基于虚关节法的3T1R混联机构静刚度特性分析

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农业机械学报 2021年第9期52卷 400-409页

作者：朱小蓉吴俣沈惠平常州大学机械工程学院常州213164

基于虚关节法和构件有限元分析建立了考虑驱动副、滚珠丝杆副、线性导轨和运动杆件弹性变形的3T1R混联机构静刚度矩阵模型。通过在构件末端添加多自由度虚拟关节的方式来等效构件的弹性,将支链等效为一系列刚性构件,通过主动副、被动副... 详细信息

基于虚关节法和构件有限元分析建立了考虑驱动副、滚珠丝杆副、线性导轨和运动杆件弹性变形的3T1R混联机构静刚度矩阵模型。通过在构件末端添加多自由度虚拟关节的方式来等效构件的弹性,将支链等效为一系列刚性构件,通过主动副、被动副以及虚拟关节连接的形式,给出了运动关节和虚拟关节变量对机构末端位姿的映射,应用虚功原理得到机构静平衡方程,推导了机构在一定外载下的刚度矩阵模型,采用无量纲变换法定义了局部线刚度和角刚度评价指标与全局线刚度和角刚度评价指标,据此分析了混联机构在典型位姿和工作空间域内的静刚度性能,并利用有限元仿真验证了刚度模型的准确性。结果表明,所建半解析刚度模型具有较高的精度;机构z向线刚度在工作空间内关于x=y轴线对称分布;机构x向、y向的线刚度沿x轴、y轴方向不变,具有解耦性;机构线刚度远大于角刚度。

关键词：混联机构静刚度虚关节法有限元分析