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Use of Controlled Release Fertilizer for Increasing N Efficiency of Direct Seeding Rice

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Pedosphere 2001年第4期11卷 333-339页

作者： FU JIANRONG, zhu YUANHONG and JIANG lina Institute of Soil and Fertilizer, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021 (China) 浙江省农业科学院土壤与肥料所浙江杭州 310021

Field trials on a silt-loamy paddy soil derived from shallow-sea deposit in direct seeding rice fields were conducted in Zhejiang, China, in 1996 to compare N efficiency of controlled release fertilizers (LP fertilizers) with the conventional urea. Six treatments including CK (no N fertilizer), conventional urea and different types of LP fertilizers at different rates were designed for two succeeding crops of early and late rice. A blend of different types of LP fertilizers as a single preplant "co-situs" application released N in a rate and amount synchronizing with uptake pattern of direct seeding rice. A single preplant application of the LP fertilizers could meet the N requirement of rice for the whole growth period without need of topdressing. Using LP fertilizer blends, equivalent grain yields could be maintained even if the N fertilization rates were reduced by 25%～50% compared with the conventional urea. Agronomic efficiency of the LP fertilizers was 13.6%～ 86.4% higher than that of the conventional urea in early rice and 100%～164.1% in late rice, depending on the amounts of the LP fertilizers applied. N fertilizer recovery rate increased from 27.4% for the conventional application of urea to 41.7%～54.l% for the single preplant "co-situs" application of the LP fertilizers. Use of the LP fertilizers was promising if the increase in production costs due to the high LP fertilizer prices could be compensated by increase in yield and N efficiency, reduction in labor costs and improvement in environment.

关键词： controlled release fertilizer direct seeding rice N efficiency

Epilepsy control during an epidemic:emerging approaches and a new management framework

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Acta Epileptologica 2020年第1期2卷 39-47页

作者： Deng Chen lina zhu Xin Lin Zhen Hong Shichuo Li Ling Liu Dong Zhou Department of Neurology West China HospitalSichuan UniversityChengdu 610041China. Department of Neurology Shanghai Huashan HospitalFudan UniversityShanghai 200040China. China Association Against Epilepsy(CAAE) Beijing 10044China.

Epidemics are a big threat to world *** ongoing pandemic of corona virus disease 2019(COVID-19)has caused a series of challenges to public *** such challenge is the management of chronic diseases such as epilepsy during an epidemic *** on this topic are rather limited and the related medical practice is full of *** we review recent development of potential approaches for epilepsy control during an epidemic and propose a new three-level management framework to address these challenges.

关键词： Epidemic Epilepsy Disease control

基于微流控技术的蛋白质结晶及其筛选方法的研究进展

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高等学校化学学报 2014年第1期35卷 1-11页

作者：朱丽娜祝莹方群浙江大学化学系微分析系统研究所杭州310058

微流控技术以其高通量、低消耗和集成化等优点成为蛋白质结晶微型化研究的重要手段.本文综述了基于微流控技术的蛋白质结晶技术和方法,主要包括微泵微阀、液滴(Droplet)、滑动芯片(SlipChip)以及液滴实验室(DropLab)等技术.此外,还针对... 详细信息

微流控技术以其高通量、低消耗和集成化等优点成为蛋白质结晶微型化研究的重要手段.本文综述了基于微流控技术的蛋白质结晶技术和方法,主要包括微泵微阀、液滴(Droplet)、滑动芯片(SlipChip)以及液滴实验室(DropLab)等技术.此外,还针对当前膜蛋白在结构生物学研究中的重要地位,综述了应用于膜蛋白结晶的微流控技术的研究进展.

关键词：微流控学蛋白质结晶基于PDMS的微泵微阀液滴膜蛋白

The H2BG53D oncohistone directly upregulates ANXA3 transcription and enhances cell migration in pancreatic ductal adenocarcinoma

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Signal Transduction and Targeted Therapy 2020年第1期5卷 1482-1485页

作者： Yi Ching Esther Wan Jiaxian Liu lina zhu Tze Zhen Evangeline Kang Xiaoxuan zhu John Lis Toyotaka Ishibashi Charles G.Danko Xin Wang Kui Ming Chan Department of Biomedical Sciences City University of Hong KongHong KongChina Key Laboratory of Biochip Technology Biotech and Health CentreShenzhen Research Institute of City University of Hong KongShenzhenChina Department of Molecular Biology and Genetics Cornell UniversityNew YorkNYUSA Division of Life Science Hong Kong University of Science and TechnologyHong KongChina USA James A Baker Institute for animal health Cornell UniversityNew YorkNYUSA

Dear Editor,Histones are essential proteins in compacting genomic DNA and regulating gene *** studies on histone H3 oncohistones in pediatric brain cancers1,2 and chondroblastoma3,documented the transcriptomic reprogramming through the alterations of histone *** recently reported the identification of a novel cancer associated mutation,the H2BG53-to-D in pancreatic ductal adenocarcinoma(PDAC)*** showed that the H2BG53D mutation weakens the interaction between nucleosomal DNA and histone octamer,subsequently enhances transcription in *** further showed that cells expressing the G53D mutant H2B acquired oncogenic phenotypes in our CRISPRCas9 knock-in ***,the mechanism by which H2BG53D mutation promotes PDAC remains unknown.

关键词： H2B expression adenocarcinoma

Multifunctional dual-anion compensation of amphoteric glycine hydrochloride enabled highly stable perovskite solar cells with prolonged carrier lifetime

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Nano Research 2024年第6期17卷 5131-5137页

作者： lina Qin Mengfei zhu Yuren Xia Xingkai Ma Daocheng Hong Yuxi Tian Zuoxiu Tie Zhong Jin State Key Laboratory of Coordination Chemistry MOE Key Laboratory of Mesoscopic ChemistryMOE Key Laboratory of High Performance Polymer Materials and TechnologyJiangsu Key Laboratory of Advanced Organic MaterialsSchool of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China Nanjing Tieming Energy Technology Co.Ltd. Nanjing 210093China Suzhou Tierui New Energy Technology Co.Ltd. Suzhou 215228China

Throughout years,the two-step spin-coating process is the most common method to prepare organic lead halide perovskite ***,the short reaction time of dropping the solution at the second step means that PbI2 cannot be completely transformed into perovskite *** solve this problem,we report the introduction of glycine hydrochloride(GlyHCl)into the second step of the two-step spin-coating process to prepare a FA_(0.9)MA_(0.1)PbI_(3-x)%-GlyHCl perovskite material(namely FAMA-x%-GlyHCl,where FA=formamidinium,MA=methylammonium,and x%stands for the molar ratio of GlyHCl added in FA iodide/MA iodide(FAI/MAI)precursor solution).The Cl−ion in GlyHCl assists the formation ofα-phase perovskite,and the-COO−group coordinates with Pb2+cation in a bridging way,making up for the anion vacancy in perovskite lattice and resulting in high absorption *** perovskite solar cells(PSCs)based on FAMA-9%-GlyHCl achieve a long carrier lifetime(527.0 ns),a photoelectric conversion efficiency(PCE)of 19.40%and good thermal stability,maintaining 85.8%of the initial PCE after being continuously heated at 60℃for 500 *** study helps to solve the problem of incomplete reaction in the two-step spin-coating process and puts forward a new solution for preparing high coverage perovskite films with large grain size.

关键词： dual-anion compensation glycine hydrochloride perovskite solar cells carrier lifetime thermal and moisture stability

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尿沉渣评分对急性肾损伤诊断的临床应用研究

中华检验医学杂志 2024年第5期47卷 548-553页

作者：张慧续薇曲林琳赵春贺单洪丽张勤高洪臣孙文瑞朱丽娜张月闫欣杨笑权王婉宁张东付尧赵旭何亮吉林大学第一医院检验科长春130021 北华大学医学技术学院吉林132013 吉林大学第一医院肾病内科长春130021 吉林大学第一医院重症医学科长春130021 吉林大学第一医院肝胆胰内科长春130021 吉林大学第一医院普通外科中心胃结直肠外科长春130021

目的:评估尿沉渣评分(USS)在急性肾损伤(AKI)的早期诊断、病因鉴别、分期及预后判断中的临床应用,探讨独立的USS及其联合血尿素氮(Bun)、血清肌酐(sCr)和尿酸(UA)对AKI的诊断效能。方法:收集2023年8月23日至9月28日期间吉林大学第一医... 详细信息

目的:评估尿沉渣评分(USS)在急性肾损伤(AKI)的早期诊断、病因鉴别、分期及预后判断中的临床应用,探讨独立的USS及其联合血尿素氮(Bun)、血清肌酐(sCr)和尿酸(UA)对AKI的诊断效能。方法:收集2023年8月23日至9月28日期间吉林大学第一医院住院患者9020份晨尿标本,经Sysmex UF5000检测,筛出小而圆形上皮细胞(SRC)>1/μl和/或管型(CAST)>1/μl 3226份进行尿沉渣镜检,选取肾小管上皮细胞和/或CAST阳性的404例入组,其中男218例,女186例,年龄59.5(49.0,71.0)岁。404例分组方法:依据镜检结果的USS分为USS AKI组(345例)和USS非AKI组(59例);依据改善全球肾脏病预后组织(KDIGO)标准,分为KDIGO标准AKI组(63例)和KDIGO标准非AKI组(341例);依据病历记载的临床诊断,分为临床诊断AKI组(29例)和临床诊断非AKI组(375例);通过查阅病历,对KDIGO标准AKI组按病因分为肾性AKI组(33例)和非肾性AKI组(30例)。采用χ^(2)检验或Fisher精确检验比较不同AKI病因、分期的USS。采用Logistic回归法计算发生肾性AKI及3期AKI的优势比。应用受试者工作特征曲线下面积评价USS、sCr、UA、Bun单独及联合诊断AKI的敏感度、特异度并计算诊断AKI的最佳截断值、敏感度与特异度。结果:以USS对KDIGO标准AKI组进行病因鉴别,肾性与非肾性AKI的USS比较差异有统计学意义(χ^(2)=11.070,P<0.001)。与USS=1相比,当USS≥2分时肾性AKI的优势比为8.125(95%CI 2.208~29.901)。以USS进行AKI分期研究,各期USS的组间比较差异有统计学意义(χ^(2)=15.724,P<0.05)。与USS=1分相比,当USS≥2分时发生3期AKI优势比为9.714(95%CI 1.145~82.390)。独立的USS诊断AKI的AUC为0.687(95%CI 0.618~0.757,P<0.001),特异度65.7%,敏感度61.9%;USS联合Bun、sCr、UA诊断AKI的AUC为0.794(95%CI 0.608~0.980,P<0.05),特异度82.4%,敏感度88.9%。结论:USS≥2分提示发生肾性AKI或3期AKI的可能性增加,USS联合Bun、sCr、UA可提高AKI诊断效能。

关键词：尿尿沉渣评分急性肾损伤尿沉渣镜检检验临床应用

Antimony doped CsPbI_(2)Br for high-stability all-inorganic perovskite solar cells

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Nano Research 2024年第3期17卷 1508-1515页

作者： Mengfei zhu lina Qin Yuren Xia Junchuan Liang Yaoda Wang Daocheng Hong Yuxi Tian Zuoxiu Tie Zhong Jin State Key Laboratory of Coordination Chemistry Ministry of Education(MOE)Key Laboratory of Mesoscopic ChemistryMOE Key Laboratory of High Performance Polymer Materials and TechnologyJiangsu Key Laboratory of Advanced Organic MaterialsSchool of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China Nanjing Tieming Energy Technology Co. Ltd.Nanjing 210093China Suzhou Tierui New Energy Technology Co. Ltd.Suzhou 215228China

All-inorganic perovskites,adopting cesium(Cs+)cation to completely replace the organic component of A-sites of hybrid organic–inorganic halide perovskites,have attracted much attention owing to the excellent thermal ***,all-inorganic iodine-based perovskites generally exhibit poor phase stability in ambient ***,we propose an efficient strategy to introduce antimony(Sb^(3+))into the crystalline lattices of CsPbI_(2)Br perovskite,which can effectively regulate the growth of perovskite crystals to obtain a more stable perovskite *** to the much smaller ionic radius and lower electronegativity of trivalent Sb^(3+)than those of Pb^(2+),the Sb^(3+)doping can decrease surface defects and suppress charge recombination,resulting in longer carrier lifetime and negligible *** a result,the all-inorganic perovskite solar cells(PSCs)based on 0.25%Sb^(3+)doped CsPbI_(2)Br light absorber and screen-printable nanocarbon counter electrode achieved a power conversion efficiency of 11.06%,which is 16%higher than that of the control devices without Sb^(3+)***,the Sb^(3+)doped all-inorganic PSCs also exhibited greatly improved endurance against heat and *** to the use of low-cost and easy-to-process nanocarbon counter electrodes,the manufacturing process of the all-inorganic PSCs is very convenient and highly repeatable,and the manufacturing cost can be greatly *** work offers a promising approach to constructing high-stability all-inorganic PSCs by introducing appropriate lattice doping.

关键词： all-inorganic perovskite solar cells Sb doped cesium lead halide perovskites foreign B-site ions hole-conductor-free phase stability improvement

应用功能磁共振成像判断急性肾损伤患者肾脏慢性病变及预测肾功能转归

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肾脏病与透析肾移植杂志 2024年第3期33卷 201-206页

作者：余雅真张薇周涵徐峰朱丽娜张龙江刘志红张炯南方医科大学第一临床医学院(东部战区总医院)国家肾脏疾病临床医学研究中心南京210016 南方医科大学第一临床医学院(东部战区总医院)放射诊断科

目的:探索功能磁共振(fMRI)在评估急性肾损伤(AKI)患者是否存在慢性基础肾脏病变及肾功能预后转归中的价值。方法:回顾性分析国家肾脏疾病临床医学研究中心诊断为AKI并同时行fMRI检查及肾活检的13例患者资料。收集患者常规病理数据(包... 详细信息

目的:探索功能磁共振(fMRI)在评估急性肾损伤(AKI)患者是否存在慢性基础肾脏病变及肾功能预后转归中的价值。方法:回顾性分析国家肾脏疾病临床医学研究中心诊断为AKI并同时行fMRI检查及肾活检的13例患者资料。收集患者常规病理数据(包括免疫荧光、光镜、电镜)以及病理诊断,统计患者fMRI中体素内不相干运动成像的标准表观弥散系数参数值(IVIM Standard-ADC)和磁共振弹性成像(MRE)的弹性参数值,估算的肾小球滤过率(eGFR)在基线和12月内的随访数据,分析IVIM Standard-ADC和弹性参数值与随访期间eGFR变化斜率之间的关系。结果:13例AKI患者中男性8例、女性5例,中位年龄33(21~44)岁。平均基线eGFR为31(16.5~43.5)mL/(min·1.73 m^(2)),随访中平均年eGFR变化斜率为12.29(4.42~25.66)。经肾活检病理证实,7例存在基础慢性病变,6例为单纯AKI。12月随访中eGFR变化斜率与IVIM Standard-ADC及45 Hz条件下的弹性值均无明显相关关系,但与60 Hz条件下的弹性值呈显著正相关(rs=0.709,P=0.022),进一步将两者作回归分析可得出60 Hz条件下的弹性值可作为随访12月eGFR变化斜率的预测因素(r^(2)=0.456,P=0.032)。45 Hz条件下的弹性值也得到同样类似的结果,可作为随访12月eGFR变化斜率的预测因素(r^(2)=0.440,P=0.036)。即MRE可相对区分肾脏损伤程度及不同的eGFR恢复斜率。结论:MRE可作为一种新的方法预测AKI患者肾功能预后情况。相比于单纯AKI患者,AKI合并CKD患者的肾功能难以完全恢复正常,二者基线弹性值有显著差别。

关键词：功能磁共振急性肾损伤肾功能预后肾小球滤过率

基于ERAS理念的妇科日间手术围术期管理最佳证据总结

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中国计划生育和妇产科 2024年第4期16卷 87-93页

作者：童慧朱丽娜刘丽丽马晶晶王大玉孟贝贝崔笑敏南京大学医学院附属鼓楼医院妇科江苏南京210008

目的系统检索、提取、汇总和分析基于ERAS理念的妇科日间手术围术期管理的最佳证据。方法计算机检索BMJ Best Practice、Up-To-Date、Cochrane Library、美国国立实践指南库(AHRQ)、国际指南协作网(G-I-N)、加拿大医学实践指南库(CMA)... 详细信息

目的系统检索、提取、汇总和分析基于ERAS理念的妇科日间手术围术期管理的最佳证据。方法计算机检索BMJ Best Practice、Up-To-Date、Cochrane Library、美国国立实践指南库(AHRQ)、国际指南协作网(G-I-N)、加拿大医学实践指南库(CMA)、苏格兰校际指南网(SIGN)、新西兰指南研究组(NZGG)、英国国家临床优化研究所(NICE)、加拿大安大略注册护士协会(RANO)、美国妇科腔镜协会(AAGL)、加拿大妇产科医师协会(SOGC)、Ovid、CINAHL、Web-of-Science、EMbase、PubMed、CNKI、万方数据库等检索平台中关于日间手术围术期管理的所有信息,包括临床实践、证据总结、临床意见、专家共识、系统评价等,同时整合证据,检索时间为建库至2023年2月。结果最终纳入文献11篇,分别为指南3篇、临床决策2篇、专家共识6篇,总结归纳出5个维度29条证据,包括全面的术前宣教、术前评估及管理策略、术中管理策略、术后管理策略、出院宣教及术后随访。结论本研究总结出基于ERAS理念的妇科日间手术围术期管理的29条证据,为临床护理提供循证实践依据,提高临床护理质量。

关键词：日间手术妇科快速康复循证护理证据总结